scholarly journals Vitamin C in Human Health and Disease

Nutrients ◽  
2021 ◽  
Vol 13 (5) ◽  
pp. 1595
Author(s):  
Dariusz Nowak
Keyword(s):  
Eighteenth Century ◽  
Vitamin C ◽  
Human Health ◽  
Citrus Fruit ◽  
Ancient Egypt ◽  
Vitamin Supplement ◽  
Vitamin C Deficiency ◽  
Health And Disease

Although the symptoms related to vitamin C deficiency were known in ancient Egypt and eighteenth century Scottish surgeon James Lind found that scurvy (a disease resulting from insufficient dietary ingestion of vitamin C) could be effectively treated with citrus fruit, this vitamin was discovered only in the year 1912 and then after 21 years it was chemically synthetized and introduced to the market as the first vitamin supplement [...]

scholarly journals Vitamin C in human health and disease

2021 ◽  
Vol 12 ◽  
pp. 142
Author(s):  
Seyed Ali Khonsary
Keyword(s):  
Vitamin C ◽  
Human Health ◽  
Health And Disease

Molecular Evidence of Bacteremia by Gastrointestinal Pathogenic Bacteria in an Infant Mummy From Ancient Egypt

2000 ◽  
Vol 124 (11) ◽  
pp. 1614-1618
Author(s):  
Albert Zink ◽  
Udo Reischl ◽  
Hans Wolf ◽  
Andreas G. Nerlich
Keyword(s):  
Vitamin C ◽  
Pathogenic Bacteria ◽  
Polymerase Chain Reaction Amplification ◽  
Ancient Egypt ◽  
Molecular Evidence ◽  
Chronic Anemia ◽  
Vitamin C Deficiency ◽  
Ancient Egyptian ◽  
First Case ◽  
Systemic Spread

Abstract In this study, we describe an infant mummy from ancient Egypt that showed macromorphologic signs of chronic anemia and vitamin C deficiency. From this infant, we have obtained a sterile sample from a metatarsal bone to extract ancient bacterial DNA. Following polymerase chain reaction amplification and subcloning of the amplicons, the sequence of the 16S ribosomal DNA was determined in several resulting clones. The presence of pathogenic and apathogenic bacteria, such as Escherichia coli, are indicated by our result, providing evidence of bacteremia, which probably contributed to death due to septicemia. These findings suggest that the infant, who already had chronic anemia and vitamin C deficiency, acquired a gastrointestinal infection, which finally led to a systemic spread. To our knowledge, this is the first case identifying potentially septicemic bacterial dissemination in an ancient Egyptian mummy. Using our approach, we hope to investigate distinct paleomicrobiological aspects of ancient populations, which will potentially enlighten our understanding of the development and evolution of pathogenic bacteria.

scholarly journals Plant-Derived Extracellular Vesicles: Current Findings,Challenges, and Future Applications

Membranes ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. 411
Author(s):  
Nader Kameli ◽  
Anya Dragojlovic-Kerkache ◽  
Paul Savelkoul ◽  
Frank R. Stassen
Keyword(s):  
Human Health ◽  
Extracellular Vesicles ◽  
Preliminary Results ◽  
In Vivo Experiments ◽  
Health And Disease ◽  
Conducting Research ◽  
Protocol Standardization ◽  
Insight Into

In recent years, plant-derived extracellular vesicles (PDEVs) have gained the interest of many experts in fields such as microbiology and immunology, and research in this field has exponentially increased. These nano-sized particles have provided researchers with a number of interesting findings, making their application in human health and disease very promising. Both in vitro and in vivo experiments have shown that PDEVs can exhibit a multitude of effects, suggesting that these vesicles may have many potential future applications, including therapeutics and nano-delivery of compounds. While the preliminary results are promising, there are still some challenges to face, such as a lack of protocol standardization, as well as knowledge gaps that need to be filled. This review aims to discuss various aspects of PDEV knowledge, including their preliminary findings, challenges, and future uses, giving insight into the complexity of conducting research in this field.

Sign in / Sign up

Export Citation Format

Share Document