scholarly journals DeltaF508 CFTR Hetero- and Homozygous Paediatric Patients with Cystic Fibrosis Do Not Differ with Regard to Nutritional Status

Nutrients ◽  
2021 ◽  
Vol 13 (5) ◽  
pp. 1402
Author(s):  
Aleksandra Mędza ◽  
Katarzyna Kaźmierska ◽  
Bartosz Wielgomas ◽  
Lucyna Konieczna ◽  
Ilona Olędzka ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Nutritional Status ◽  
Serum Levels ◽  
The Body ◽  
Erythrocyte Membranes ◽  
Paediatric Patients ◽  
Patient Groups ◽  
The Mean ◽  
Body Mass Indexes ◽  
Homozygous Patient

The purpose of this study was to compare the nutritional status between deltaF508 CFTR hetero- and homozygous paediatric patients with cystic fibrosis. We assessed the percentage profiles of fatty acids measured in erythrocyte membranes and the serum levels of vitamins A, D3, E and K1 in the studied groups. We also measured the weights and heights and calculated the body mass indexes (BMIs). The studied groups consisted of 34 heterozygous and 30 homozygous patients. No statistically significant differences were found in the serum vitamins or erythrocyte membrane fatty acid profiles between the hetero- and homozygous patient groups, except for heptadecanoic acid (p = 0.038). The mean percentiles of height, weight and BMI did not differ significantly between the two groups. The homozygous and heterozygous paediatric patients with cystic fibrosis were similar in terms of their nutritional statuses.

scholarly journals PREVALENCE OF HEPATIC STEATOSIS AMONG CHILDREN AND ADOLESCENTS WITH CYSTIC FIBROSIS AND ITS ASSOCIATION WITH NUTRITIONAL STATUS

2019 ◽  
Vol 37 (4) ◽  
pp. 435-441
Author(s):  
Amanda Oliva Gobato ◽  
Ana Carolina Junqueira Vasques ◽  
Antonio Fernando Ribeiro ◽  
Roberto Massao Yamada ◽  
Gabriel Hessel
Keyword(s):  
Cystic Fibrosis ◽  
Nutritional Status ◽  
Children And Adolescents ◽  
Hepatic Steatosis ◽  
Statistical Tests ◽  
The Body ◽  
Significant Difference ◽  
Group A ◽  
The Mean ◽  
Group B

ABSTRACT Objective: To determine the prevalence of hepatic steatosis (HS) in children and adolescents with cystic fibrosis (CF) and associate it with nutritional status. Methods: Cross-sectional study with children and adolescents with CF diagnosis. Weight and height were used to calculate the body mass index (BMI) and subsequent classification of the nutritional status. The midarm circumference (MAC), triceps skinfold thickness (TSF) and midarm muscle circumference (MAMC) were used to evaluate body composition. Abdominal ultrasonography was performed for diagnosis of HS. The statistical tests used were Student’s t test, Mann-Whitney test and chi-square test with significance level of 5%. Results: 50 patients with CF were evaluated, 18 (36%) were diagnosed with HS (Group A) and 32 (64%) without HS (Group B). The mean age of Group A was 13,2±4,9 years old and Group B 11,7±4,9; for BMI, the value for Group A was 18,0±4,1 and Group B was 15,7±3,8; the TSF of Group A was 8,4±3,5 mm and Group B was 7,0±2,5 mm. For these variables, there was no significant difference between the groups. The mean of MAC and MAMC differed significantly between the groups, being higher in the HS group, with p values of 0,047 and 0,043. Conclusions: The frequency of HS in patients with CF is high and it is not related to malnutrition, according to the parameters of BMI, TSF and MAMC. The values of MAC and MAMC indicated a greater reserve of muscle mass in patients with HS.

scholarly journals Assessment of the Nutritional Status of Hospitalized Type 2 Diabetic Patients

2021 ◽  
Vol 5 (Supplement_2) ◽  
pp. 841-841
Author(s):  
Nadia Ben Amor ◽  
Faten Mahjoub ◽  
Olfa Berriche ◽  
Henda Jamoussi
Keyword(s):  
Weight Loss ◽  
Nutritional Status ◽  
The Body ◽  
Prise En Charge ◽  
Elderly Subjects ◽  
Diabetic Patients ◽  
Type 2 Diabetic Patients ◽  
The Mean ◽  
Type 2 Diabetic

Abstract Objectives The aim of our work was to assess the nutritional status and to determine the prevalence of undernutrition in type 2 diabetic patients hospitalized in a center specializing in Nutrition, Diabetology and Metabolic Diseases. Methods This is a descriptive cross-sectional prospective study, which involved 40 type 2 diabetic patients, aged 18 and over, hospitalized in department A of the National Institute of Nutrition and Food Technology. The assessment of nutritional status was carried out using clinical means (kinetics of weight loss, a dietary survey, anthropometric measurements, impedancemetry, Nutritional Risk Score 2002 for those under 70 years old and the Mini Nutritional Assessment from 70 years old) and biological (albuminemia). The positive diagnosis of malnutrition was selected according to the criteria of the High Authority of Health of 2019 for adults under 70 years, and of 2007 for elderly subjects. Results The mean age was 59.6 ± 11.59 years old. The average duration of diabetes was 10.83 ± 8.03 years. The mean level of glycated hemoglobin was 11.03 ± 1.97% and the Body Mass Index was 28.88 kg/m² with extremes ranging from 14.6 to 40.9 kg/m². Weight loss was noted in 48% of patients. Calorie intake was low in 30% of the patients. Protein and mono-unsaturated fatty acid low intake was noted in respectively 28% and 70% of patients. More than half of patients had deficiency in vitamin C, D, B12 and B9 as well as in zinc, calcium, magnesium and cooper. Iron and vitamin B12 low intake was more prevalent in patients with malnutrition (p = 0.043 and p = 0.003 respectively). The mean serum albumin was 37.58 ± 2.93 g/l with ranges ranging from 27.2 to 43.8 g/l. Malnutrition was diagnosed in 25% of patients and in half of the cases, it was severe. Conclusions Patients with type 2 diabetes mellitus are at high risk of malnutrition with a high prevalence of dietary intakes deficiencies. Funding Sources 1. HAS. Diagnostic de la dénutrition de l'enfant et l'adulte. Service de bonnes pratiques professionnelles, 2019. 2. HAS. Stratégie de prise en charge en cas de dénutrition protéino-énergétique chez la personne âgée. Service des recommandations professionnelles. Avril 2007. 3. Anses. Actualisation des repères du PNNS: élaboration des références nutritionnelles. Saisie n° 2012-SA-0186. Avis de l'Anses. Rapport d'expertise collective. Décembre 2016.

scholarly journals Body composition of women with and without dynapenia defined by different cut-off points

2021 ◽  
Vol 34 ◽  
Author(s):  
Lucas dos SANTOS ◽  
Camille Giehl Martins MIRANDA ◽  
Tasso Carvalho Barberino de SOUZA ◽  
Thais Alves BRITO ◽  
Marcos Henrique FERNANDES ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Body Composition ◽  
Nutritional Status ◽  
Postmenopausal Women ◽  
Muscle Mass ◽  
Handgrip Strength ◽  
The Body ◽  
Electrical Bioimpedance ◽  
Central Fat ◽  
The Mean

ABSTRACT Objective To compare body composition of postmenopausal women with and without dynapenia, defined by different cut-off points. Methods Body composition was assessed by electrical bioimpedance and the nutritional status by the body mass index. Dynapenia was diagnosed according to handgrip strength, using the following cut-off points: handgrip strength <16kgf and <20 kgf. Results A total of 171 women (50 to 92 years of age) participated in the investigation. The mean age of non-dynapenic and dynapenic women (handgrip strength <20kgf) was 69.4±8.2 and 74.5±8.2 years, respectively. The mean age of women with dynapenia (handgrip strength <16kgf) was 75.0±10.1 years and non-dynapenic women, 71.1±8.2 years. It was found that dynapenic women, with handgrip strength <20 and <16kgf, had an average of 2.38 and 2.47kg less muscle mass respectively, when compared to non-dynapenic women (p<0.05). However, there was no difference in muscle mass between the different dynapenic groups. Non-dynapenic women (handgrip strength ≥20kgf) had more total (3.55kg) and central fat (1.47kg) (p<0.05). Conclusion Dynapenic women, diagnosed considering both cutoff points, had less total and segmental muscle mass compared to non-dynapenic women. In addition, dynapenic women with handgrip strength <20kgf had lower total and trunk adiposity.

scholarly journals Relação dos Parâmetros Derivados da Bioimpedância Elétrica com o Estado Nutricional de Pacientes em Hemodiálise

2017 ◽  
Vol 21 (2) ◽  
pp. 98
Author(s):  
Marilia Firmino De Castro Ribeiro ◽  
Juliana Megumi Nisio dos Reis ◽  
Ana Paula Bazanelli
Keyword(s):  
Nutritional Status ◽  
Phase Angle ◽  
Negative Correlation ◽  
Cell Mass ◽  
Bioelectrical Impedance ◽  
Hemodialysis Patients ◽  
The Body ◽  
Body Cell Mass ◽  
Body Cell ◽  
The Mean

Os parâmetros não tradicionais derivados da bioimpedância elétrica (BIA) como reatância, ângulo de fase e massa celular estão cada vez sendo mais utilizados na prática clínica para auxiliar no diagnóstico nutricional dos pacientes com doença renal crônica e, consequentemente, no prognóstico clínico dessa população. O presente estudo teve por objetivo avaliar a relação dos parâmetros derivados da BIA com o estado nutricional de pacientes em hemodiálise. Estudo transversal, realizado com trinta pacientes adultos de uma clínica de Nefrologia localizada na região metropolitana de São Paulo. Foi utilizada a BIA para avaliar esses parâmetros, assim como para avaliar a composição corporal. A amostra foi constituída por homens e mulheres com média de idade de aproximadamente 56 anos. O ângulo de fase dos pacientes foi de 5,9±1,6 graus e apresentou uma correlação negativa com idade (r= -0,69, p< 0,001) e água corporal extracelular (r= -0,93 p< 0,001). A média de reatância foi de 50,9±16,08 ohms e apresentou correlação negativa com a água extracelular (r= -0,82, p<0,001) e positiva com a massa celular (r=0,51, p<0,004). Em relação ao percentual de massa celular, a média foi de 36,8± 6,1%, sendo que a mesma apresentou uma correlação negativa com a idade (r= -0,66, p< 0,001), gordura corporal (r= -0,73, p< 0,001), água corporal extracelular (r= -0,82, p<0,001).Conclui-se que os parâmetros não tradicionais derivados da BIA apresentaram boa associação com o estado nutricional dos pacientes, podendo dessa forma, serem aliados importantes para obtenção do melhor diagnóstico nutricional e, consequentemente, do prognóstico dos mesmos durante o tratamento dialítico.Palavras-chave: Bioimpedância Elétrica. Estado Nutricional. Diálise.AbstractNon-traditional parameters derived from bioelectrical impedance analysis (BIA) as reactance, phase angle and cell mass are increasingly being used in clinical practice to improve the nutritionalstatus of chronic kidney disease patients andthe clinical outcomes in this population. The present study aimed to evaluate the relationship of parameters derived from the BIA with nutritional status of hemodialysis patients. It was a cross-sectional study with 30 adultspatients of a nephrology clinic in the metropolitan region of São Paulo. BIA was used to evaluate as well as to assess the body composition. The mean age of the patients was approximately 56 years. The phase angle of the patients was 5.9 ± 1.6 degrees and it was negatively correlated with age (r = -0.69, p <0.001) andwith extracellular body water (r = -0.93 p <0.001). The mean reactance was 50.9 ± 16.08 ohms and it showed a negative correlation with the extracellular water (r = -0.82, p <0.001) and positively with the body cell mass (r = 0.51, p <0.004). Regarding to the percentage of body cell mass, the mean was 36.8 ± 6.1%, and it presented a negative correlation with age (r = -0.66, p <0.001), body fat (r = -0.73, p <0.001) and with body water extracellular (r = -0.82, p <0.001). The present study concluded that non-traditional parameters derived from BIA showed a good association with the nutritional status of hemodialysis patients. It is important for getting the best nutritional diagnosis and consequently the prognosis of these patientsduring the dialysis treatment.Keywords: Bioelectrical Impedance. Nutritional Status. Dialysis.

Malnutrition and related factors in Filipino patients with Parkinson’s disease: results from a pilot study

2021 ◽  
Author(s):  
Nikolai Gil D Reyes ◽  
Roland Dominic G Jamora ◽  
Marianne Rae M Baltazar ◽  
Alfand Marl F Dy Closas
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Nutritional Status ◽  
Associated Factors ◽  
The Body ◽  
Related Factors ◽  
Bidirectional Relationship ◽  
Daily Dose ◽  
The Mean ◽  
Levodopa Equivalent Daily Dose

Aim: Emerging evidence demonstrates a bidirectional relationship between nutritional status and Parkinson’s disease (PD). Our aim was to determine the local prevalence of malnutrition and associated factors among Filipino PD patients. Materials & methods: We assessed the nutritional status of 95 PD patients using the body mass index (BMI) and Subjective Global Assessment (SGA) and identified malnutrition-associated factors. Results & conclusion: In our sample, the mean BMI was 24.5 ± 4.2 kg/m2. Consistent with published estimates, five (5.3%) patients were classified as underweight and 57 (60%) patients were classified as overweight/obese. A total of 30 (31.6%) patients had abnormal nutritional status based on SGA. Weight-adjusted levodopa equivalent daily dose was a significant factor (p = 0.032) for BMI, while dysphagia and higher weight-adjusted levodopa equivalent daily dose were found to be predictive of abnormal nutritional status using SGA (adjusted odds ratio of 8.85 [95% CI: 1.59–49.17; p = 0.015] and 1.10 [95% CI: 1.02–1.20; p = 0.021], respectively).

Nocturnal hyperalimentation via a gastrostomy tube in children with cystic fibrosis

2021 ◽  
Vol 16 (2) ◽  
pp. 22-34
Author(s):  
I. Sokolov ◽  
◽  
E.A. Roslavtseva ◽  
V.P. Chernevich ◽  
N.I. Burkina ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Lung Function ◽  
Nutritional Status ◽  
Body Weight Gain ◽  
Forced Expiratory Volume ◽  
Gastrostomy Tube ◽  
Percutaneous Endoscopic Gastrostomy Tube ◽  
Endoscopic Control ◽  
Low Profile ◽  
The Mean

Objective. To assess the efficacy of nocturnal hyperalimentation via a low-profile gastrostomy tube for in the improvement of nutritional status and lung function in children with severe cystic fibrosis (CF). Patients and methods. We used nocturnal hyperalimentation with a nutrient solution via a low-profile gastrostomy tube installed under endoscopic control to improve nutritional status of 16 CF children with severe protein-calorie malnutrition aged between 5.5 and 17.5 years. The mean duration of nocturnal hyperalimentation was 1.3 years (range: 7 months–54 months). The nutritional status was evaluated using the WHOAntho Plus software; pulmonary function was evaluated by assessing forced expiratory volume in 1 minute (FEV1) and the number of bronchopulmonary exacerbations per year. Results. All children demonstrated an improvement in their weight and height. After the first 12 months, the mean body weight gain was 5 kg; during the second and third years, children gained 4 kg and nearly 2 kg, respectively. The mean increase in height was 7 cm in the first year, 10 cm in the second year, and 4 cm in the third year. All patients except one had an increase in FEV1 and fewer exacerbations. Complications after gastrostomy were rare and easily addressed. Conclusion. Nocturnal hyperalimentation via a percutaneous endoscopic gastrostomy tube is an effective and safe method of improving nutritional status in children with CF, which delays the progression of bronchopulmonary lesions and lung function reduction, improves the prognosis and quality of life. Key words: cystic fibrosis, children, nutritional status, lung function, enteral nutrition, low-profile gastrostomy tube, nocturnal hyperalimentation

scholarly journals Physical Growth and Nutritional Status among Ao Naga Children of Nagaland, Northeast India

2013 ◽  
Vol 2013 ◽  
pp. 1-6 ◽  
Author(s):  
Temsumongla Longkumer
Keyword(s):  
Body Mass Index ◽  
Nutritional Status ◽  
Body Mass ◽  
Northeast India ◽  
The Body ◽  
Physical Growth ◽  
The Mean

The present study was carried out on 571 Ao Naga children including 289 boys and 282 girls aged 8 to 15 years from Mokokchung town, Nagaland. This study tried to find out the physical growth according to the height and weight and nutritional status according to the body mass index (BMI) following the classification by Cole et al. Our study revealed that the girls were taller than boys till 13 years and the boys became taller thereafter. As for weight, the girls were heavier during 10 to 14 years. The mean height and weight increased as the age advanced in both boys and girls. The prevalence of underweight was 30.12% and the prevalence of overweight was 2.28% among the Ao Naga children, and the girls were found to have a higher prevalence of overweight and the boys had a higher prevalence of underweight. This revealed that both underweight and overweight coexisted among the Ao Naga children from Mokokchung town, although the prevalence of overweight was not high.

scholarly journals Evaluation of Serum Levels of LP-PLA2 and CA-242 in Adult Male Cigarette Smokers in Nnewi Metropolis

2019 ◽  
Vol 5 (1) ◽  
pp. 31-35
Author(s):  
P.O Manafa ◽  
◽  
N.B Nwankwo ◽  
Ekuma Okereke O ◽  
G.O Chukwuma ◽  
...  
Keyword(s):  
Developing Countries ◽  
Serum Level ◽  
Cigarette Smoking ◽  
Adult Male ◽  
Serum Levels ◽  
The Body ◽  
Cigarette Smokers ◽  
Ca 242 ◽  
Significant Difference ◽  
The Mean

Background: Cigarette smoking is a behavioural lifestyle in which a substance is burned and the resulting smoke breathed into the body system. Thus, cigarette smoking is a known public health challenge given the number of tobacco-related diseases like hypertension, lung cancer, cardiovascular diseases (CVD) etc. leading to increased mortality in developed and developing countries. Notwithstanding that the effects of smoking are well documented, individuals who practice cigarette smoking are still on the increase most especially in the developing countries. Study Design/Aim: This was a cross-sectional study designed to evaluate the serum levels of Cancer Antigen-242 (CA-242) and Lipoprotein-Associated Phospholipase A2 (Lp-PLA2) in adult male smokers in Nnewi Metropolis, as emerging inflammatory biomarkers. Materials and methods: A total of 135 subjects aged between 16-65 years were selected for this study. They were classified into 2 major groups (test and control); comprising of 85 cigarette smokers (55 and 30 as test subjects for the evaluation of CA-242 and Lp-PLA2) respectively and 50 non-cigarette smokers (35 and 15 as control subjects for CA-242 and Lp-PLA2 evaluations) respectively. A well-structured questionnaire was used for the collation of information from the participants. Results: the mean serum level of Lp-PLA2 was significantly elevated (P<0.05) in cigarette smokers (67.52±27.29) compared with the non-smokers (63.63±20.81). While the serum level of CA-242 among smokers (1.77±0.70) was of no significant difference (P=0.711) when compared with the non-smokers (1.81±0.20). More so, the mean serum levels of Lp-PLA2 correlated positively with the duration of smoking (r=0.297) and age (r=0.085) in male cigarette smokers. However, there were negative relationships when CA-242 were correlated with duration of smoking (r = -0.156) and age of smokers (r=-0.155). Conclusion: The increased level of Lp-PLA2 along with its positive correlation with other traditional markers like age and smoking duration suggests that Lp-PLA2 is a suitable biomarker to predict cardiac related diseases among cigarette smokers. This is because, Lp-PLA2 is a more specific cardiac predictor compared to the non-specific conventional biomarkers. We therefore suggest that Lp-PLA2 as an independent advanced predictor of cardiovascular disease be further evaluated using follow-up studies with better sample size in CVDs related cases

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