scholarly journals The Effects of Bariatric Surgery on Vitamin B Status and Mental Health

Nutrients ◽  
2021 ◽  
Vol 13 (4) ◽  
pp. 1383
Author(s):  
Amna Al Mansoori ◽  
Hira Shakoor ◽  
Habiba I. Ali ◽  
Jack Feehan ◽  
Ayesha S. Al Dhaheri ◽  
...  

Diet is a modifiable factor that ensures optimal growth, biochemical performance, improved mood and mental functioning. Lack of nutrients, notably vitamin B, has an impact on human health and wellbeing. The United Arab Emirates is facing a serious problem of micronutrient deficiencies because of the growing trend for bariatric surgery, including Roux-en-Y gastric bypass and sleeve gastrectomy. People undergoing bariatric surgery are at high risk of developing neurological, cognitive, and mental disabilities and cardiovascular disease due to deficiency in vitamin B. Vitamin B is involved in neurotransmitter synthesis, including γ-aminobutyric acid, serotonin, dopamine, and noradrenaline. Deficiency of vitamin B increases the risk of depression, anxiety, dementia and Alzheimer’s disease. In addition, vitamin B deficiency can disrupt the methylation of homocysteine, leading to hyperhomocysteinemia. Elevated homocysteine levels are detrimental to human health. Vitamin B deficiency also suppresses immune function, increases the production of pro-inflammatory cytokines and upregulates NF-κB. Considering the important functions of vitamin B and the severe consequences associated with its deficiency following bariatric surgery, proper dietary intervention and administration of adequate supplements should be considered to prevent negative clinical outcomes.

2016 ◽  
Vol 12 (7) ◽  
pp. S107
Author(s):  
Suriya Punchai ◽  
Zubaidah Nor Hanipah ◽  
Gautam Sharma ◽  
emre bucak ◽  
Dvir Froylich ◽  
...  

2017 ◽  
Vol 27 (8) ◽  
pp. 2079-2082 ◽  
Author(s):  
Suriya Punchai ◽  
Zubaidah Nor Hanipah ◽  
Katherine M Meister ◽  
Philip R Schauer ◽  
Stacy A Brethauer ◽  
...  

2011 ◽  
Vol 81 (4) ◽  
pp. 238-239 ◽  
Author(s):  
Manfred Eggersdorfer ◽  
Paul Walter

Nutrition is important for human health in all stages of life - from conception to old age. Today we know much more about the molecular basis of nutrition. Most importantly, we have learnt that micronutrients, among other factors, interact with genes, and new science is increasingly providing more tools to clarify this interrelation between health and nutrition. Sufficient intake of vitamins is essential to achieve maximum health benefit. It is well established that in developing countries, millions of people still suffer from micronutrient deficiencies. However, it is far less recognized that we face micronutrient insufficiencies also in developed countries.


Proceedings ◽  
2019 ◽  
Vol 8 (1) ◽  
pp. 19
Author(s):  
Nicola Gillies ◽  
Amber M. Milan ◽  
Pankaja Sharma ◽  
Brenan Durainayagam ◽  
Sarah M. Mitchell ◽  
...  

Background: Maintaining optimal status of folate and metabolically [...]


1937 ◽  
Vol 24 (2) ◽  
pp. 263-267 ◽  
Author(s):  
Karl S. Bernhardt ◽  
Ruth Herbert

Author(s):  
Aviva Fattal-Valevski

Thiamine (vitamin B1) was the first B vitamin to have been identified. It serves as a cofactor for several enzymes involved in energy metabolism. The thiamine-dependent enzymes are important for the biosynthesis of neurotransmitters and for the production of reducing substances used in oxidant stress defenses, as well as for the synthesis of pentoses used as nucleic acid precursors. Thiamine plays a central role in cerebral metabolism. Its deficiency results in dry beriberi, a peripheral neuropathy, wet beriberi, a cardiomyopathy with edema and lactic acidosis, and Wernicke—Korsakoff syndrome, whose manifestations consist of nystagmus, ophthalmoplegia, and ataxia evolving into confusion, retrograde amnesia, cognitive impairment, and confabulation. Patients on a strict thiamine-deficient diet display a state of severe depletion within 18 days. The most common cause of thiamine deficiency in affluent countries is either alcoholism or malnutrition in nonalcoholic patients. Treatment by thiamine supplementation is beneficial for diagnostic and therapeutic purposes.


A number of investigators have observed atrophy and degenerative changes in the testes of animals fed on diets deficient in the factor termed Vitamin B. Funk and Douglas (5) reported that the testicles of pigeons showing symptoms of avian polyneuritis were greatly atrophied, and that the tubules were diminished in size and contained no spermatozoa. Drummond (3) observed a similar condition in the testes of adult rats deprived of vitamin B, whilst McCarrison (8) found the atrophy of the male gonads to be very much more severe in pigeons with beri-beri than in monkeys with that disease. Allen examined the testes of rats which had been fed on Osborne and Mendels’ diet deficient in vitamin B, and found considerable derangements, to which further reference will be made in the section on Histology.


1929 ◽  
Vol 177 (2) ◽  
pp. 307-308
Author(s):  
W. B. ROSE ◽  
C. J. STUCKY ◽  
G. R. COWGILL.

2018 ◽  
Vol 121 (7) ◽  
pp. 756-762
Author(s):  
M. Dinu ◽  
G. Pagliai ◽  
F. Cesari ◽  
B. Giusti ◽  
A. M. Gori ◽  
...  

AbstractPrevious studies have suggested that vegetarianism can result in a reduction of vitamin B12 circulating levels. The aim of the present study was to investigate the effects of a 3-month dietary intervention with a lacto-ovo-vegetarian diet (VD) on the levels of circulating vitamin B12 in a group of omnivores. We analysed fifty-four omnivorous subjects who followed a VD as a first dietary intervention within the CARDIVEG (Cardiovascular Prevention with Vegetarian Diet) study, a dietary intervention study. VD resulted in a significant reduction (P<0·001) of 51·2 % of vitamin B12 intake and in a significant reduction (P=0·005) of 6·2 % of the circulating levels of vitamin B12 (–24·5 pg/ml). Changes in vitamin B12 intake were significantly correlated with changes in circulating levels of vitamin B12 (R 0·61, P<0·001). Subgroup analyses showed that reduction in circulating vitamin B12 levels was more evident in participants who were younger, overweight, non-smokers and had hypercholesterolaemia. A logistic regression analysis showed that a reduction in vitamin B12 intake greater than the first quartile of the delta changes obtained in the study population (–28·5 %) conferred a significantly higher risk of experiencing a decrease in circulating vitamin B12 levels (OR 10·1; 95 % CI 1·3, 76·1). In conclusion, a 3-month VD period determined a significant reduction in circulating levels of vitamin B12, being significantly correlated with the reduction in vitamin B12 intake. Although a well-planned VD can provide adequate nutrition across all life stages, special care must be taken to ensure adequate vitamin B12 intake and to help prevent deficiency.


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