scholarly journals Gastric Cancer and the Daily Intake of the Major Dish Groups Contributing to Sodium Intake: A Case-Control Study in Korea

Nutrients ◽  
2021 ◽  
Vol 13 (4) ◽  
pp. 1365
Author(s):  
Jung-Hyun Kwak ◽  
Chang-Soo Eun ◽  
Dong-Soo Han ◽  
Yong-Sung Kim ◽  
Kyu-Sang Song ◽  
...  

Studies on the association between gastric cancer (GC) and the intake of soup-based dish groups (noodles and dumplings, soups, and stews), which are sodium-contributing foods, in Korea are insufficient, and the results of studies on the intake of pickled vegetables such as kimchi are inconsistent. This study aimed to determine the association between the incidence of GC and the daily intake of high-sodium dish groups (noodles and dumplings, soups, stews, and pickled vegetables) and whether these associations differ depending on behavioral risk factors for GC. In this case-control study, subjects aged 20–79 years were recruited from two hospitals between December 2002 and September 2006. A total of 440 cases and 485 controls were recruited, of which 307 pairs were matched and included for the analysis. In our results, a higher intake of noodles and dumplings was associated with a significantly increased incidence of GC. In the participants who consumed past or current alcohol, a higher intake of noodles and dumplings was associated with a significantly increased incidence of GC. Our results suggest that efforts to reduce the daily sodium intake from noodles and dumplings are needed to prevent and reduce the incidence of GC.

BMJ Open ◽  
2020 ◽  
Vol 10 (9) ◽  
pp. e042341
Author(s):  
Ping Yuan ◽  
Lan Lin ◽  
Kuicheng Zheng ◽  
Wen Wang ◽  
Sihan Wu ◽  
...  

ObjectiveTo explore the relationships between gastric cancer and serum pepsinogen I (PG I), PG II, PG I/II ratio, gastrin 17 (G-17) and Helicobacter pylori infection, and to investigate dietary and lifestyle risk factors for gastric cancer in Fujian Province, China.DesignA hospital-based, 1:1 matched case–control study.SettingPatients with newly diagnosed gastric cancer were recruited from the Fujian Provincial Hospital and the No. 900 Hospital of the Joint Support Force of the Chinese People’s Liberation Army between July 2014 and December 2016.ParticipantsA total of 180 pairs of patients with gastric cancer and control subjects were recruited in the study, including 134 (74.4%) male pairs and 46 (25.6%) female pairs.Investigation and analysis measuresSerological indicators were tested with ELISA kits. Dietary, lifestyle and psychological factors were investigated through face-to-face questionnaire. Relationships between gastric cancer and these influencing factors were examined by Χ2 test and conditional logistic regression.ResultsSerum PG II and G-17 levels and H. pylori infection rate were higher in patients with gastric cancer than in control subjects (p<0.05), while PG I/II ratio was lower in patients with gastric cancer (p<0.05). Serum G-17 levels were higher in patients with corpus gastric cancer than in patients with antral gastric cancer (p<0.05). Serum PG II levels were higher in patients with advanced gastric cancer than in patients with early-stage cancer (p<0.05), however, PG I/II ratio was lower in patients with advanced-stage gastric cancer than in patients with early-stage cancer (p<0.05). Eating hot food (OR=2.32), eating pickled vegetables (OR=4.05) and often feel troubled (OR=2.21) were found to significantly increase the risk of gastric cancer (all p<0.05), while consuming onion or garlic (OR=0.35), drinking tea (OR=0.26), eating fresh fruits (OR=0.55), and high serum PG I (OR=0.99) or PG I/II ratio (OR=0.73) were found to be protective against gastric cancer.ConclusionStudy results showed that serum PG, G-17 and H. pylori antibodies could be useful indicators for early diagnosis of gastric cancer. Increase in serum G-17 level might indicate the location of gastric cancer. Increase in serum PG II level and decrease in PG I/II ratio might imply the clinical stage. Eating hot food, eating pickled vegetables and often feel troubled may be risk factors for gastric cancer, while eating fresh fruits, eating onion or garlic, and drinking tea may be protective factors against the disease.


Author(s):  
Hirofumi Sugita ◽  
Shinichi Sakuramoto ◽  
Yoshiaki Mihara ◽  
Kazuaki Matsui ◽  
Keiji Nishibeppu ◽  
...  

2007 ◽  
Vol 102 (1) ◽  
pp. 40-45 ◽  
Author(s):  
Khean-Lee Goh ◽  
Phaik-Leng Cheah ◽  
Noorfaridah Md ◽  
Kia-Fatt Quek ◽  
Navaratnam Parasakthi

2018 ◽  
Vol 64 (7) ◽  
pp. 611-619 ◽  
Author(s):  
Marcus Fernando Kodama Pertille Ramos ◽  
Ulysses Ribeiro Júnior ◽  
Juliana Kodaira Yukari Viscondi ◽  
Bruno Zilberstein ◽  
Ivan Cecconello ◽  
...  

2000 ◽  
Vol 15 (5) ◽  
pp. 510 ◽  
Author(s):  
Young Sik Kim ◽  
Hyun Ah Park ◽  
Byung Sik Kim ◽  
Jeong Hwan Yook ◽  
Moo Song Lee

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