scholarly journals Intrauterine Transfer of Polyunsaturated Fatty Acids in Mother–Infant Dyads as Analyzed at Time of Delivery

Nutrients ◽  
2021 ◽  
Vol 13 (3) ◽  
pp. 996
Author(s):  
Vanessa Woodard ◽  
Melissa Thoene ◽  
Matthew Van Ormer ◽  
Maranda Thompson ◽  
Corrine Hanson ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Fatty Acid ◽  
Polyunsaturated Fatty Acids ◽  
Cord Blood ◽  
Acid Level ◽  
Plasma Concentrations ◽  
P Value ◽  
Nutrient Transfer ◽  
Fatty Acid Level ◽  
Tissue Samples

Polyunsaturated fatty acids (PUFAs) are essential for fetal development, and intrauterine transfer is the only supply of PUFAs to the fetus. The prevailing theory of gestational nutrient transfer is that certain nutrients (including PUFAs) may have prioritized transport across the placenta. Numerous studies have identified correlations between maternal and infant fatty acid concentrations; however, little is known about what role maternal PUFA status may play in differential intrauterine nutrient transfer. Twenty mother–infant dyads were enrolled at delivery for collection of maternal and umbilical cord blood, and placental tissue samples. Plasma concentrations of PUFAs were assessed using gas chromatography (GC-FID). Intrauterine transfer percentages for each fatty acid were calculated as follows: ((cord blood fatty acid level/maternal blood fatty acid level) x 100). Kruskal–Wallis tests were used to compare transfer percentages between maternal fatty acid tertile groups. A p-value < 0.05 was considered significant. There were statistically significant differences in intrauterine transfer percentages of arachidonic acid (AA) (64% vs. 65% vs. 45%, p = 0.02), eicosapentaenoic acid (EPA) (41% vs. 19% vs. 17%, p = 0.03), and total fatty acids (TFA) (27% vs. 26% vs. 20%, p = 0.05) between maternal plasma fatty acid tertiles. Intrauterine transfer percentages of AA, EPA, and TFA were highest in the lowest tertile of respective maternal fatty acid concentration. These findings may indicate that fatty acid transfer to the fetus is prioritized during gestation even during periods of maternal nutritional inadequacy.

Free fatty acid level in rat liver after ingestion of polyunsaturated fatty acids

Lipids ◽  
1969 ◽  
Vol 4 (1) ◽  
pp. 77-79 ◽  
Author(s):  
Akira Yamamoto ◽  
Masahiro Isozaki ◽  
Takeshi Ishibe ◽  
Mitsuo Nishikawa
Keyword(s):  
Fatty Acids ◽  
Fatty Acid ◽  
Free Fatty Acid ◽  
Polyunsaturated Fatty Acids ◽  
Rat Liver ◽  
Acid Level ◽  
Free Fatty Acid Level ◽  
Fatty Acid Level

Plasma glycerophospholipid profile, erythrocyte n–3 PUFAs, and metabolic syndrome incidence: a prospective study in Chinese men and women

2021 ◽  
Author(s):  
Shuangshuang Chen ◽  
Qingqing Wu ◽  
Li Zhu ◽  
Geng Zong ◽  
Huaixing Li ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Fatty Acids ◽  
Polyunsaturated Fatty Acids ◽  
Animal Studies ◽  
Plasma Concentrations ◽  
Positive Association ◽  
Community Dwelling ◽  
P Value ◽  
Total N ◽  
Long Chain

ABSTRACT Background Animal studies have highlighted critical roles of glycerophospholipid (GP) metabolism in various metabolic syndrome (MetS)-related features such as dyslipidemia, obesity, and insulin resistance. However, human prospective studies of associations between circulating GPs and risks of MetS are scarce. Objectives We aimed to investigate whether GPs are associated with incidence of MetS in a well-established cohort. Methods A total of 1243 community-dwelling Chinese aged 50–70 y without MetS at baseline and followed up for 6 y were included in current analyses. A total of 145 plasma GPs were quantified by high-throughput targeted lipidomics. MetS was defined using the updated National Cholesterol Education Program Adult Treatment Panel III criteria for Asian Americans. Results After 6 y, 429 participants developed MetS. Eleven GPs, especially those with long-chain polyunsaturated fatty acids (LCPUFAs) or very-long-chain polyunsaturated fatty acids (VLCPUFAs) at the sn-2 position, including 1 phosphatidylcholine (PC) [PC(18:0/22:6)], 9 phosphatidylethanolamines (PEs) [PE(16:0/22:6), PE(18:0/14:0), PE(18:0/18:1), PE(18:0/18:2), PE(18:0/20:3), PE(18:0/22:5), PE(18:0/22:6), PE(18:1/22:6), and PE(18:2/22:6)], and 1 phosphatidylserine (PS) [PS(18:0/18:0)], were positively associated with incident MetS (RRs: 1.16–1.30 per SD change; Bonferroni-corrected P &lt; 0.05). In network analysis, the strongest positive association for MetS incidence was evidenced in a module mainly composed of PEs containing C22:6 and PSs [RR: 1.21; 95% CI: 1.12, 1.31 per SD change; Bonferroni-corrected P &lt; 0.05]. This association was more pronounced in participants with lower erythrocyte total n–3 PUFA concentrations [Bonferroni-corrected Pinter(P value for the interaction)&lt; 0.05]. Conclusions Elevated plasma concentrations of GPs, especially PEs with LCPUFAs or VLCPUFAs at the sn-2 position, are associated with higher risk of incident MetS. Future studies are merited to confirm our findings.

scholarly journals The determination of volatile fatty acids in the caecum of the conscious rabbit

1976 ◽  
Vol 35 (3) ◽  
pp. 365-371 ◽  
Author(s):  
D. S. Parker ◽  
R. T. Mcmillan
Keyword(s):  
Fatty Acids ◽  
Fatty Acid ◽  
Volatile Fatty Acid ◽  
Acid Level ◽  
Volatile Fatty Acids ◽  
Fatty Acid Content ◽  
Diurnal Fluctuation ◽  
Fatty Acid Level ◽  
Conscious Rabbit

1. A method of obtaining dialysed samples from the caecum of the conscious rabbit is described.2. Values for total volatile fatty acid content and for molar proportions of individual volatile fatty acids in dialysate samples were in good agreement with those obtained from caecal material.3. The volatile fatty acid level in the caecum throughout the day was determined using two groups of animals, one group fed ad lib. and the other group on a restricted food intake. These results indicated a marked diurnal fluctuation in volatile fatty acid level in the caecum of rabbits fed once/d which was not evident in those fed ad lib.

scholarly journals Trans Fatty Acids in Human Milk in Latvia: Association with Dietary Habits during the Lactation Period

Nutrients ◽  
2021 ◽  
Vol 13 (9) ◽  
pp. 2967
Author(s):  
Līva Aumeistere ◽  
Alīna Beluško ◽  
Inga Ciproviča ◽  
Dace Zavadska
Keyword(s):  
Fatty Acids ◽  
Fatty Acid ◽  
Human Milk ◽  
Trans Fatty Acid ◽  
Trans Fatty Acids ◽  
Acid Level ◽  
Dietary Habits ◽  
Vaccenic Acid ◽  
Fatty Acid Level ◽  
Lactating Women

The human milk fatty acid, including trans fatty acid, composition is predominantly affected by the maternal diet. The aim of this research was to determine the trans fatty acid level in human milk among lactating women in Latvia, and to evaluate how maternal dietary habits affect the trans fatty acid composition of human milk. In total, 70 lactating women participated in this cross-sectional study. A 72-hour food diary and food frequency questionnaire were used to evaluate maternal dietary habits. Different trans fatty acids in human milk samples were determined using gas chromatography (Agilent 6890N, Agilent Technologies Incorporated, the United States). Overall, the dietary intake of trans fatty acids among the participants was 0.54 ± 0.79 g per day. The total trans fatty acid level in the human milk samples was 2.30% ± 0.60%. The composition of trans fatty acids found in human milk was associated with maternal dietary habits. Higher elaidic acid, vaccenic acid and total trans fatty acid levels in human milk were found among participants with a higher milk and dairy product intake. Meat and meat product intake were associated with a higher vaccenic acid and total trans fatty acid levels in human milk. A moderate association was also established between maternal trans fatty acid intake and the total trans fatty acid level in human milk. The obtained correlations indicate that maternal dietary habits during lactation can impact the composition of trans fatty acids found in human milk.

scholarly journals Blood hematology profile at postpartum in Ettawa grade does fed with different fatty acid flushing diets during the late gestation period and different litter sizes

2020 ◽  
Vol 151 ◽  
pp. 01002
Author(s):  
Prasetyo Nugroho ◽  
Komang G. Wiryawan ◽  
Wasmen Manalu ◽  
Dewi A. Astuti
Keyword(s):  
Fatty Acids ◽  
Fatty Acid ◽  
Immune System ◽  
Linolenic Acid ◽  
Acid Level ◽  
Physiological Stress ◽  
Late Gestation ◽  
Gestation Period ◽  
Normal Range ◽  
Fatty Acid Level

Physiological stress occurs in does immediately after parturition. This study evaluated the blood hematology profile at postpartum in Ettawa grade does fed with different fatty acid flushing diets during the late gestation period and different litter sizes (LS). A total of 15 Ettawa grade does with a gestational age of 4 months were used in this study during the flushing period. The flushing ration was supplemented with a 2.8% fatty acid level in lauric acid (T1), α-linolenic acid (T2) and α-linolenic acid (T3). A factorial randomized complete design 3 x 2 in which the first factor was fatty acids and the second factor was litter sizes (LS1 and LS2) was used to measure blood hematology. Leukocyte level was higher in LS2 compared to LS1 (P<0.05), but it was not affected by fatty acids. Even though the lymphocyte level was highest in T3 and LS2 (P<0.05), it was still in the normal range. Monocyte and neutrophil were lower in T3 compared to T1 (P<0.05), but it was similar to T2. In conclusion, the results suggest that flushing in the late gestation period with supplementation of 2.8% α-linolenic acid improved the immune system at postpartum on the does giving birth to twins 2.

scholarly journals Maternal and Cord Blood Saturated Fatty Acid Level and Infant Adiposity

2021 ◽  
Vol 16 (2) ◽  
pp. 119-128
Author(s):  
Yustiyani Yustiyani ◽  
Faisal Anwar ◽  
Mira Dewi
Keyword(s):  
Fatty Acid ◽  
Cord Blood ◽  
Saturated Fatty Acid ◽  
Acid Level ◽  
Fatty Acid Level

scholarly journals Fatty acid profiles of muscle, liver, heart and kidney of Australian prime lambs fed different polyunsaturated fatty acids enriched pellets in a feedlot system

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Hung Van Le ◽  
Don Viet Nguyen ◽  
Quang Vu Nguyen ◽  
Bunmi Sherifat Malau-Aduli ◽  
Peter David Nichols ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Fatty Acid ◽  
Polyunsaturated Fatty Acids ◽  
Fatty Acid Profiles

Growth and carcass characteristics of three lamb genotypes finished on the same level of feeding

2000 ◽  
Vol 70 (1) ◽  
pp. 51-61 ◽  
Author(s):  
L. O. W. McClintont ◽  
A. F. Carson
Keyword(s):  
Fatty Acids ◽  
Body Weight ◽  
Fatty Acid ◽  
Weight Gain ◽  
Polyunsaturated Fatty Acids ◽  
Body Weight Gain ◽  
Saturated Fatty Acids ◽  
Carcass Characteristics ◽  
Live Weight ◽  
Ash Content

AbstractThis study investigated the efficiency of growth and the carcass characteristics of 24 Greyface (Border Leicester × Scottish Blackface), 24 Texel (12 purebred and 12 Texel × Texel-Greyface) and 24 Rouge (12 purebred and 12 Rouge × Rouge-Greyface) lambs finished on the same level of feeding. The efficiency of live-weight gain (kg/MJ) was higher in Greyface compared with Texel lambs (P< 0·01). The efficiency of empty body-weight gain (kg/MJ) was higher in Greyface (P< 0·01) and Rouge (P< 0·05) compared with Texel lambs. The efficiency of carcass gains (kg/MJ) tended to be higher in Greyface and Rouge compared with Texel lambs (P= 0·07). The efficiency of non-carcass component gains (kg/MJ) was also higher in Greyface compared with Texel lambs (P0·05). Carcass water, protein, lipid and ash gains did not vary significantly between the genotypes, however carcass energy gain tended to be higher in Greyface and Rouge compared with Texel lambs (P= 0·08). The relative proportions of water, protein, lipid and ash in carcass gains did not vary significantly between the genotypes. At the end of the experiment carcass water content was higher in Texel compared with Greyface lambs (P< 0·05) and carcass ash content was lower in Texel compared with Greyface (P< 0·01) and Rouge (P< 0·05) lambs. The concentration of saturated fatty acids was higher in Greyface compared with Rouge lambs (P< 0·001) and higher in Rouge compared with Texel lambs (P< 0·05). Monounsaturated fatty acid concentrations were higher in Rouge compared with Greyface lambs (P< 0·05) and higher in Texel compared with Rouge lambs (P< 0·001). Polyunsaturated fatty acid concentrations were higher in Rouge and Texel compared with Greyface lambs (P< 0·01). The ratio of n-6:n-3 fatty acids was lower in Rouge compared with Greyface lambs (P< 0·05).The efficiency of empty body gain was higher in male compared with female lambs (P< 0·05). Carcass water (P< 0·01) and protein (P< 0·05) gains were higher in male lambs. At the end of the experiment male carcasses contained a higher content of water (P< 0·05), protein (P< 0·01) and ash (P= 0·07), and a lower lipid (P< 0·05) and energy (P< 0·001) content. Carcass lipids from male lambs contained a higher concentration of polyunsaturated fatty acids (P< 0·001) and tended to contain a lower concentration of saturated fatty acids (P = 0·06).

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