scholarly journals Maternal Vitamin D Levels during Late Pregnancy and Risk of Allergic Diseases and Sensitization during the First Year of Life—A Birth Cohort Study

Nutrients ◽  
2020 ◽  
Vol 12 (8) ◽  
pp. 2418
Author(s):  
Fui Chee Woon ◽  
Yit Siew Chin ◽  
Intan Hakimah Ismail ◽  
Amir Hamzah Abdul Latiff ◽  
Marijka Batterham ◽  
...  
Keyword(s):  
Vitamin D ◽  
Cohort Study ◽  
Pregnant Women ◽  
Late Pregnancy ◽  
Allergic Diseases ◽  
Birth Cohort Study ◽  
First Year ◽  
Maternal Vitamin ◽  
Vitamin D Levels ◽  
First Year Of Life

Allergic diseases are the most common chronic illness in childhood. Findings from developed countries have reported associations between Vitamin D levels during pregnancy and offspring allergy risk. This prospective cohort study aimed to determine the associations between maternal Vitamin D levels during late pregnancy and allergic diseases in Malaysian infants during the first year of life. Serum 25(OH)D concentrations of 380 pregnant women in the third trimester were measured using a chemiluminescent immunoassay. Children’s allergic outcomes were assessed at 3, 6, and 12 months based on parental reports. Specific IgE antibodies against food and inhalant allergens were measured in infants at 12 months of age. A total of 43.2% pregnant women were Vitamin D deficient (<30 nmol/L) and 56.8% were nondeficient (≥30 nmol/L). A total of 27.6% of the infants had eczema, 6.1% had wheeze, 27.4% had food sensitization, 10.8% had inhalant allergen sensitization, and 3.8% had IgE-mediated food allergy during the first year of life. Compared with the nondeficient group, maternal Vitamin D deficiency in late pregnancy was not associated with any allergic outcomes after adjustment for potential confounding factors. In conclusion, the present study does not support an association between maternal Vitamin D levels in late pregnancy and allergic outcomes during the first year of life.

Vitamin D supplementation during the first year of life and risk of schizophrenia: a Finnish birth cohort study

2004 ◽  
Vol 67 (2-3) ◽  
pp. 237-245 ◽  
Author(s):  
John McGrath ◽  
Kaisa Saari ◽  
Helinä Hakko ◽  
Jari Jokelainen ◽  
Peter Jones ◽  
...  
Keyword(s):  
Vitamin D ◽  
Cohort Study ◽  
Birth Cohort ◽  
Vitamin D Supplementation ◽  
Birth Cohort Study ◽  
First Year ◽  
First Year Of Life

scholarly journals Impact of Maternal Vitamin D Status on the Formation of Atopic Dermatitis in Young Children

2021 ◽  
Vol 8 ◽  
pp. 2333794X2110229
Author(s):  
Mariam Petriashvili
Keyword(s):  
Vitamin D ◽  
Atopic Dermatitis ◽  
Young Children ◽  
Pregnant Women ◽  
Allergic Diseases ◽  
Maternal Vitamin ◽  
Low Concentrations ◽  
Vitamin D Levels ◽  
Relationship Of ◽  
The Impact

Recent studies have highlighted relationship of allergic diseases with vitamin D deficiency. The aim of the study was to evaluate the impact of maternal vitamin D levels in pregnancy on the formation of atopic dermatitis in early life. A total of 186 pregnant women and their infants who developed atopic dermatitis before the age of 2 years were involved in the prospective study. Most pregnant women (57.5%) were diagnosed with 25(OH)D deficiency (3.6 ± 4.4 ng/ml) ( P = .000). Maternal 25(OH)D deficiency was directly related to atopic family anamnesis and relatively high IgE levels. In these cases, children developed atopic dermatitis before the age of 6 months (70.8%) with prevalence of moderate-severity (55%) and persistent course (68.3%) of the disease. The above mentioned supported the idea that the peculiarities of the formation of atopic dermatitis in young children are associated with low concentrations of vitamin D in mothers during pregnancy.

scholarly journals Anthropometry at birth and at age of routine vaccination to predict mortality in the first year of life: A birth cohort study in BukinaFaso

PLoS ONE ◽  
2019 ◽  
Vol 14 (3) ◽  
pp. e0213523 ◽  
Author(s):  
Martha Mwangome ◽  
Moses Ngari ◽  
Paluku Bwahere ◽  
Patrick Kabore ◽  
Marie McGrath ◽  
...  
Keyword(s):  
Cohort Study ◽  
Birth Cohort ◽  
Routine Vaccination ◽  
Birth Cohort Study ◽  
First Year ◽  
First Year Of Life

scholarly journals Breastfeeding and Infant Eczema in the First Year of Life in the KOALA Birth Cohort Study: A Risk Period-Specific Analysis

PEDIATRICS ◽  
2007 ◽  
Vol 119 (1) ◽  
pp. e137-e141 ◽  
Author(s):  
B. E. P. Snijders ◽  
C. Thijs ◽  
I. Kummeling ◽  
J. Penders ◽  
P. A. van den Brandt
Keyword(s):  
Cohort Study ◽  
Birth Cohort ◽  
Birth Cohort Study ◽  
First Year ◽  
Specific Analysis ◽  
Risk Period ◽  
First Year Of Life ◽  
Infant Eczema

scholarly journals The role of parathyroid hormone during pregnancy on the relationship between maternal vitamin D deficiency and fetal growth restriction: a prospective birth cohort study

2020 ◽  
Vol 124 (4) ◽  
pp. 432-439
Author(s):  
Deng-Hong Meng ◽  
Ying Zhang ◽  
Shuang-Shuang Ma ◽  
Hong-Lin Hu ◽  
Jing-Jing Li ◽  
...  
Keyword(s):  
Vitamin D ◽  
Cohort Study ◽  
Parathyroid Hormone ◽  
Birth Weight ◽  
Fetal Growth ◽  
Birth Cohort Study ◽  
Maternal Vitamin ◽  
The Relationship ◽  
Prospective Birth Cohort ◽  
Prospective Birth Cohort Study

AbstractPrevious studies have shown conflicting findings regarding the relationship between maternal vitamin D deficiency (VDD) and fetal growth restriction (FGR). We hypothesised that parathyroid hormone (PTH) may be an underlying factor relevant to this potential association. In a prospective birth cohort study, descriptive statistics were evaluated for the demographic characteristics of 3407 pregnancies in the second trimester from three antenatal clinics in Hefei, China. The association of the combined status of vitamin D and PTH with birth weight and the risk of small for gestational age (SGA) was assessed by a multivariate linear and binary logistic regression. We found that declined status of 25-hydroxyvitamin D is associated with lower birth weight (for moderate VDD: adjusted β = −49·4 g, 95 % CI −91·1, −7·8, P < 0·05; for severe VDD: adjusted β = −79·8 g, 95 % CI −127·2, −32·5, P < 0·01), as well as ascended levels of PTH (for elevated PTH: adjusted β = −44·5 g, 95 % CI −82·6, −6·4, P < 0·05). Compared with the non-VDD group with non-elevated PTH, pregnancies with severe VDD and elevated PTH had the lowest neonatal birth weight (adjusted β = −124·7 g, 95 % CI −194·6, −54·8, P < 0·001) and the highest risk of SGA (adjusted risk ratio (RR) = 3·36, 95 % CI 1·41, 8·03, P < 0·01). Notably, the highest risk of less Ca supplementation was founded in severe VDD group with elevated PTH (adjusted RR = 4·67, 95 % CI 2·78, 7·85, P < 0·001). In conclusion, elevated PTH induced by less Ca supplementation would further aggravate the risk of FGR in pregnancies with severe VDD through impaired maternal Ca metabolism homoeostasis.

scholarly journals Acid-suppressive medications in the first year of life and risk of childhood asthma: a population-based birth cohort study

2020 ◽  
Vol 56 (5) ◽  
pp. 2000197 ◽  
Author(s):  
Claudio Barbiellini Amidei ◽  
Rosanna Comoretto ◽  
Loris Zanier ◽  
Daniele Donà ◽  
Anna Cantarutti ◽  
...  
Keyword(s):  
Cohort Study ◽  
Birth Cohort ◽  
Childhood Asthma ◽  
Population Based ◽  
Birth Cohort Study ◽  
First Year ◽  
First Year Of Life

VITAMIN D PROVISION FOR CHILDREN AND ADULT POPULATION OF THE AMUR REGION

2016 ◽  
Vol 1 (60) ◽  
pp. 57-61 ◽  
Author(s):  
Романцова ◽  
Elena Romantsova ◽  
Борисенко ◽  
Elena Borisenko ◽  
Бабцева ◽  
...  
Keyword(s):  
Risk Factors ◽  
Vitamin D ◽  
Pregnant Women ◽  
Vitamin D Deficiency ◽  
Respiratory Infections ◽  
Adult Population ◽  
Amur Region ◽  
Preschool Age ◽  
First Year ◽  
First Year Of Life

The aim of the research is to study the availability of vitamin D among children of different age and pregnant women living in the Amur region. 339 residents of Blagoveshchensk (279 children of different age and 60 adults) were examined. Among them there were 129 toddlers, 90 children of preschool age of 3-6 years old, 60 adolescents of 15-17 years old and 60 adults (pregnant women) of 18-40 years old. In the blood serum the content of the metabolite of vitamin D [25(OH)D] was studied by high performance liquid chromatography. The assessment of risk factors for failure and deficiency of vitamin D was conducted by clinical and anamnestic data. The first results of the study have been presented. They indicate a high frequency of various vitamin D deficiency in the population of the Amur region. Among 339 residents of the Amur region 92 (27.1%) had an adequate availability of vitamin D, 144 (42.4%) had an insufficiency of 25(OH)D; at the same time vitamin D deficiency was identified in 90 (26.5%) with 1/3 of the child population and 1/4 of pregnant women. The level of 25(OH)D within normal limits found in 37.5% of children in the first year of life decreased till 3.6 % by 3 years old, with its deficit increasing from 29.1% to 50%, persisting at this level (45.5 percent) in 3-6 year-old children, declining till 23.3% in adolescents and till 23.3% in pregnant women. The average vitamin D in the studied age periods was the highest in the first year of life (36.14±4.3 ng/ml), and the lowest in 2-3 year-old children (19.31±14.68 ng/ml), with a gradual increase in 3-6 years old (21.77±0.96 ng/ml); in 15-17 years old (23.89±0.66 ng/ml) and in pregnant women it has reached a level of 27.75±0.18 ng/ml, remaining below normal values. Respiratory infections, digestion, bone and joint systems pathologies are the most important risk factors contributing to the low status of 25 (OH) D; their prevention, alongside with the correction of vitamin D deficiency can improve the health of the population of the Amur region.

Sign in / Sign up

Export Citation Format

Share Document