scholarly journals Failure to Thrive in the Outpatient Clinic: A New Insight

Nutrients ◽  
2020 ◽  
Vol 12 (8) ◽  
pp. 2202
Author(s):  
Antonella Lezo ◽  
Letizia Baldini ◽  
Monica Asteggiano
Keyword(s):  
Failure To Thrive ◽  
Outpatient Setting ◽  
Micronutrient Deficiencies ◽  
Poor Growth ◽  
Abnormal Growth ◽  
The World ◽  
Micronutrient Malnutrition ◽  
Macro And Micronutrients ◽  
Regular Increase ◽  
Inadequate Nutrition

Failure to thrive (FTT) is an abnormal growth pattern determined by inadequate nutrition. It is a common problem in children, representing 5% to 10% of patients seen in an outpatient setting. Many definitions have been proposed based on anthropometric deterioration; however, they show poor concordance. No single definition is sufficiently sensitive in identifying faltering growth whilst a combination of multiple criteria seems more accurate. In light of the recent redefinition of pediatric malnutrition as a disequilibrium between requirements and intakes of energy, and macro- and micronutrients, a wider conception of FTT as an unsatisfactory nutritional status related to poor growth and health is useful. Although the most severe problems of micronutrient malnutrition are found in developing countries, people of all regions of the world can be affected by micronutrient deficiencies (MNDs), a form of undernutrition with relevant effects on growth and health. Changes in diets and lifestyle, elimination diets, food insecurity, and food intake disorders create the conditions at risk of faltering growth and MNDs. This new insight integrates the “classical” anthropometric criteria for definition and treatment, in the aim of warranting both a regular increase in size and an overall adequate development and health status.

scholarly journals Gas-filled urachal abscess with a pinging sound in a heifer calf

2019 ◽  
Vol 64 (No. 8) ◽  
pp. 362-366 ◽  
Author(s):  
R Sato ◽  
K Yamada ◽  
Y Shinozuka ◽  
H Ochiai ◽  
K Onda
Keyword(s):  
Fistulous Tract ◽  
Failure To Thrive ◽  
Abdominal Distension ◽  
Intravenous Urography ◽  
University Hospital ◽  
Growth Depression ◽  
Poor Growth ◽  
History Of ◽  
Heifer Calf ◽  
Urachal Abscess

A 6-month-old crossbred of a Holstein and Japanese Black heifer calf weighing 95 kg presented with a history of intermittent abdominal distension and failure to thrive. The physical examination identified a pinging sound over the dorsal left flank. The abdominal radiography showed a huge gas-filled mass. The intravenous urography revealed no communication between the mass and the urinary bladder. Although the visual examination and palpation of the umbilicus did not reveal visible abnormalities, an umbilical disease was suspected because the animal exhibited poor growth, depression, and a hunched back posture. When the eschar adhering to the centre of the umbilicus was removed, the presence of a fistulous tract was revealed. The umbilical ultrasound examination revealed an intra-abdominal abscess and the fistulography demonstrated that the abscess communicated with the umbilicus. The abscess, compressing into the rumen, was observed by computed tomography. From these images, it was diagnosed as an umbilical cord remnant abscess and a definitive diagnosis of a urachal abscess was obtained by open abdominal surgery and the subsequent removal of the mass. The calf was discharged from the university hospital on day 14 after the operation. This case shows that a urachal abscess should be considered when a pinging sound is present, even if the animal exhibits no swelling or pain of the umbilicus.

scholarly journals Are Countries of the Eastern Mediterranean Region on Track towards Meeting the World Health Assembly Target for Anemia? A Review of Evidence

2021 ◽  
Vol 18 (5) ◽  
pp. 2449
Author(s):  
Ayoub Al-Jawaldeh ◽  
Mandy Taktouk ◽  
Radhouene Doggui ◽  
Zahra Abdollahi ◽  
Baseer Achakzai ◽  
...  
Keyword(s):  
Iron Deficiency ◽  
Mediterranean Region ◽  
Eastern Mediterranean ◽  
Eastern Mediterranean Region ◽  
Reproductive Age ◽  
World Health ◽  
Deficiency Anemia ◽  
Micronutrient Deficiencies ◽  
World Health Assembly ◽  
The World

Anemia is a multifactorial condition, with a complex etiology that involves nutritional and non-nutritional factors. The misconception that iron deficiency is equivalent to anemia may mask the need to address other potential causative factors. This review paper aims to (1) assess the burden of anemia vs. iron deficiency anemia (IDA) amongst women of reproductive age (WRA), pregnant women (PW), and children under five years old (underfive children, U5C) in the Eastern Mediterranean region (EMR); (2) evaluate trends in anemia prevalence and whether countries are on track towards meeting the World Health Assembly (WHA) target for 2025; and (3) characterize anemia reduction efforts and provide a road map for future programs. A search of pertinent literature and databases was conducted. Anemia prevalence in the EMR ranged between 22.6% and 63% amongst PW, 27% and 69.6% amongst WRA, and 23.8% and 83.5% amongst U5C. Data showed that the EMR is not on course towards meeting the WHA target. The contribution of IDA to anemia was found to be less than half. Other potential contributors to anemia in the region were identified, including micronutrient deficiencies, parasitic infestations, and poor sanitation. A framework of action was proposed as a roadmap to meet the targets set by the WHA.

Review of the Micronutrient Situation in Rwanda

2021 ◽  
Vol 42 (1) ◽  
pp. 133-154
Author(s):  
Joanne E. Arsenault ◽  
Deanna K. Olney
Keyword(s):  
Life Cycle ◽  
Young Children ◽  
Vitamin A ◽  
Vitamin A Deficiency ◽  
Grey Literature ◽  
Age Groups ◽  
Reproductive Age ◽  
Micronutrient Deficiencies ◽  
Micronutrient Malnutrition ◽  
Context Specific

Background: Rwanda’s commitment to reducing malnutrition is evident in their multisectoral nutrition policy and wide array of nutrition partners. However, the prevalence of micronutrient deficiencies and the suitability of current strategies to address existing deficiencies is unclear. Objective: To review the available evidence related to the prevalence of micronutrient deficiencies across the life cycle and strategies in place to address them. Methods: We reviewed scientific and grey literature on nutritional problems in Rwanda, emphasizing micronutrient deficiencies and anemia, and current strategies to address micronutrient malnutrition. Results: Overall, there is scant evidence related to the types and prevalence of micronutrient deficiencies among populations across the life cycle in Rwanda. Existing evidence is primarily limited to outdated or small regional surveys focusing on iron or vitamin A among women and young children. Surveys have assessed the prevalence of anemia and indicate that anemia is very high among young children and moderately high among other age-groups. However, there are limited data on the context-specific causes of anemia in Rwanda across population groups. Current nutrition strategies mainly target women and young children and are primarily designed to reduce vitamin A deficiency and/or anemia caused by micronutrient deficiencies. Conclusions: Rwanda has many nutrition programs in place that address micronutrient deficiencies in young children and a few for women of reproductive age. However, gaps exist in knowledge of the extent of different types of micronutrient deficiencies among all populations across the life cycle and whether the delivery of nutrients through current programs is meeting actual needs.

scholarly journals Benefits and Limitations of Non-Transgenic Micronutrient Biofortification Approaches

Agronomy ◽  
2021 ◽  
Vol 11 (3) ◽  
pp. 464
Author(s):  
Edward Marques ◽  
Heather M. Darby ◽  
Jana Kraft
Keyword(s):  
Current Literature ◽  
The State ◽  
World Health ◽  
Micronutrient Deficiencies ◽  
Conventional Breeding ◽  
The World ◽  
Primary Focus

Increasing the amount of micronutrients in diets across the world is crucial to improving world health. Numerous methods can accomplish this such as the biofortification of food through biotechnology, conventional breeding, and agronomic approaches. Of these, biofortification methods, conventional breeding, and agronomic approaches are currently globally accepted and, therefore, should be the primary focus of research efforts. This review synthesizes the current literature regarding the state of biofortified foods through conventional breeding and agronomic approaches for crops. Additionally, the benefits and limitations for all described approaches are discussed, allowing us to identify key areas of research that are still required to increase the efficacy of these methods. The information provided here should provide a basal knowledge for global efforts that are combating micronutrient deficiencies.

The Compute Infrastructures for Big Data Analytics

2014 ◽  
pp. 74-109 ◽  
Author(s):  
Pethuru Raj
Keyword(s):  
Big Data ◽  
Data Analytics ◽  
Big Data Analytics ◽  
Data Sources ◽  
Steady Increase ◽  
Data Generation ◽  
Abnormal Growth ◽  
The World ◽  
Tremendous Amount ◽  
And Storage

The implications of the digitization process among a bevy of trends are definitely many and memorable. One is the abnormal growth in data generation, gathering, and storage due to a steady increase in the number of data sources, structures, scopes, sizes, and speeds. In this chapter, the author shows some of the impactful developments brewing in the IT space, how the tremendous amount of data getting produced and processed all over the world impacts the IT and business domains, how next-generation IT infrastructures are accordingly getting refactored, remedied, and readied for the impending big data-induced challenges, how likely the move of the big data analytics discipline towards fulfilling the digital universe requirements of extracting and extrapolating actionable insights for the knowledge-parched is, and finally, the establishment and sustenance of the dreamt smarter planet.

scholarly journals Multiplying the efficiency and impact of biofortification through metabolic engineering

2020 ◽  
Vol 11 (1) ◽  
Author(s):  
Dominique Van Der Straeten ◽  
Navreet K. Bhullar ◽  
Hans De Steur ◽  
Wilhelm Gruissem ◽  
Donald MacKenzie ◽  
...  
Keyword(s):  
Metabolic Engineering ◽  
World Population ◽  
Micronutrient Deficiencies ◽  
Sustainable Development Goal ◽  
Policy Interventions ◽  
Hidden Hunger ◽  
The World ◽  
Rational Combination ◽  
Socio Economic Impact ◽  
Staple Crop

Abstract Ending all forms of hunger by 2030, as set forward in the UN-Sustainable Development Goal 2 (UN-SDG2), is a daunting but essential task, given the limited timeline ahead and the negative global health and socio-economic impact of hunger. Malnutrition or hidden hunger due to micronutrient deficiencies affects about one third of the world population and severely jeopardizes economic development. Staple crop biofortification through gene stacking, using a rational combination of conventional breeding and metabolic engineering strategies, should enable a leap forward within the coming decade. A number of specific actions and policy interventions are proposed to reach this goal.

scholarly journals A late diagnosis of Pseudohypoaldosteronism type I in an infant with hypoplastic left heart syndrome presenting with failure to thrive

2021 ◽  
pp. 1-3
Author(s):  
Deani H. McVadon ◽  
John M. Costello ◽  
Katherine E. Twombley ◽  
Sinai C. Zyblewski
Keyword(s):  
Hypoplastic Left Heart Syndrome ◽  
Case Reports ◽  
Peripheral Resistance ◽  
Failure To Thrive ◽  
Type I ◽  
Left Heart ◽  
Hypoplastic Left Heart ◽  
Poor Growth ◽  
Left Heart Syndrome ◽  
Pseudohypoaldosteronism Type

Abstract Pseudohypoaldosteronism type I is caused by a peripheral resistance to aldosterone and can present with electrolyte abnormalities, poor growth, or dehydration. Although a rare disease, several case reports have been published regarding Pseudohypoaldosteronism type I in neonates and infants. We report a case of failure to thrive and hyponatremia in an infant with hypoplastic left heart syndrome who was subsequently found to have Pseudohypoaldosteronism type I.

scholarly journals Role of Non Androgenic Factors in Hair loss and Hair Regrowth

2017 ◽  
Vol 2 (1) ◽  
Keyword(s):  
Hair Loss ◽  
Hair Growth ◽  
Nutritive Value ◽  
Transforming Growth Factor ◽  
Hair Follicles ◽  
The Body ◽  
Immune Recognition ◽  
Micronutrient Deficiencies ◽  
Poor Growth

Multiple nutritional, environmental and lifestyle factors can directly affect hair follicles, to weaken and make them sensitive to the action of androgens. Hair loss can be corrected and hair growth can be improved by addressing these non-androgenic factors. Patients having hair fall, thinning, loss of volume and poor growth can be precursors to androgenetic alopecia. Recent research has shown that androgens inhibit hair growth through release of Transforming Growth Factor (TGF) ß1. Further study of this mechanism reveals that generation of Reactive Oxygen Species (ROS) induced by androgens leads to release of TGF ß1 and use of ROS scavengers can block the release of TGF ß1, explaining beneficial role of antioxidants in hair growth. The binding of ROS to intracellular proteins also causes hair loss by altering the protein structure, changing their immune recognition and converting them to new antigens targeted by inflammatory and immune systems. Calorie restriction and individual micronutrient deficiencies lead to a new process of intracellular destruction or autophagy before cell apoptosis, which could explain cessation of hair growth. Telogen is not a resting phase but now defined as active conservation of follicles under unfavourable conditions. Thus any stress, trauma, metabolic change or insult causes telogen. Micronutrients zinc, copper, selenium maintains immunity, control inflammation and preserve antioxidant activity of the cells. Vitamins A, C, D have a role in phagocytosis and antibodies maintaining resistance. Vitamin D3 modulates the hair-inductive capacity of dermal papilla cells. Vitamin and micronutrient deficiencies are prevalent among all the population of the world. Nutritive value of the foods has reduced over the years by 30%. Endocrine Disrupting chemicals are creating further damage to the hormonal balance of the body. All these can be countered by use of antioxidants and a well-planned nutritional program which will ensure strengthening and regrowth of hair follicles, without the use of Finasteride.

Growth faltering (failure to thrive)

2011 ◽  
Author(s):  
R. Mark Beattie ◽  
Anil Dhawan ◽  
John W.L. Puntis
Keyword(s):  
Dynamic Process ◽  
Common Factors ◽  
Failure To Thrive ◽  
Well Being ◽  
Poor Growth ◽  
Factors Influencing ◽  
Growth Faltering ◽  
Underlying Illness ◽  
Specific Organ ◽  
Physical Findings

Factors influencing growth 51Pitfalls 51Management 51Growth faltering or failure to thrive (FTT) is a descriptive term implying failure not only of growth, but also impairment of other aspects of a child's well-being. It is a dynamic process involving a failure to meet expected potential, and there is no universally accepted definition. Weight crossing down two major centile lines is often taken as an indicator of need for referral to a paediatrician. In the absence both of symptoms suggesting specific organ dysfunction (e.g. vomiting, diarrhoea, breathlessness, etc.) and physical findings other than poor growth, an underlying illness is unlikely. It is important to bear in mind common factors influencing growth, such as parental size and ...

scholarly journals Pre-operative micronutrient deficiencies in patients with severe obesity candidates for bariatric surgery

2020 ◽  
Author(s):  
M. Pellegrini ◽  
F. Rahimi ◽  
S. Boschetti ◽  
A. Devecchi ◽  
A. De Francesco ◽  
...  
Keyword(s):  
Bariatric Surgery ◽  
Vitamin B12 ◽  
Severe Obesity ◽  
Vitamin B12 Deficiency ◽  
Micronutrient Deficiencies ◽  
Reactive Protein ◽  
Inflammatory Status ◽  
Before And After ◽  
Multiple Micronutrient ◽  
Micronutrient Malnutrition

Abstract Purpose In patients with obesity, micronutrient deficiencies have been reported both before and after bariatric surgery (BS). Obesity is a chronic pro-inflammatory status, and inflammation increases the risk of micronutrient malnutrition. Our objective was to assess in pre-BS patients the prevalence of micronutrient deficiencies and their correlation with blood values of C-reactive protein (CRP). Methods Anthropometric data, instrumental examinations, and blood variables were centrally measured in the first 200 patients undergoing a pre-BS evaluation at the “Città della Salute e della Scienza” Hospital of Torino, starting from January 2018. Results At least one micronutrient deficiency was present in 85.5% of pre-BS patients. Vitamin D deficiency was the most prevalent (74.5%), followed by folate (33.5%), iron (32%), calcium (13%), vitamin B12 (10%), and albumin (5.5%) deficiency. CRP values were high (> 5 mg/L) in 65% of the patients. These individuals showed increased rate of iron, folate, vitamin B12 deficiency, and a higher number of micronutrient deficiencies. In a multiple logistic regression model, increased CRP levels were significantly associated with deficiencies of vitamin B12 (OR = 5.84; 95% CI 1.25–27.2; p = 0.024), folate (OR = 4.02; 1.87–8.66; p < 0.001), and with the presence of ≥ 2 micronutrient deficiencies (OR = 2.31; 1.21–4.42; p = 0.01). Conclusions Micronutrient deficiencies are common in patients with severe obesity undergoing BS, especially when inflammation is present. In the presence of increased CRP values before surgery, it might be advisable to search for possible multiple micronutrient deficiencies.

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