scholarly journals Association between Geriatric Nutrition Risk Index and Skeletal Muscle Mass Index with Bone Mineral Density in Post-Menopausal Women Who Have Undergone Total Thyroidectomy

Nutrients ◽  
2020 ◽  
Vol 12 (6) ◽  
pp. 1683
Author(s):  
Tai-Hua Chiu ◽  
Szu-Chia Chen ◽  
Hui-Chen Yu ◽  
Jui-Sheng Hsu ◽  
Ming-Chen Shih ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Total Thyroidectomy ◽  
Postmenopausal Women ◽  
Muscle Mass ◽  
Skeletal Muscle Mass ◽  
Mineral Density ◽  
Total Hip ◽  
T Score ◽  
Hip Bmd ◽  
Skeletal Muscle Mass Index

Background: Osteoporosis is highly prevalent in postmenopausal women and may result in fractures and disabilities. Total thyroidectomy has also been associated with loss of bone mass. The aim of this cross-sectional study was to evaluate associations among nutritional status, skeletal muscle index and markers of bone turnover to bone mineral density in postmenopausal women who had undergone total thyroidectomy. Methods: Fifty postmenopausal women who had undergone total thyroidectomy were included. Body composition was measured using dual-energy X-ray absorptiometry (DXA). The Geriatric Nutritional Risk Index (GNRI) was calculated using baseline body weight and serum albumin level. Skeletal muscle mass index was calculated as the appendicular skeletal muscle mass (ASM) divided by the height squared and assessed using DXA. Results. Multivariate stepwise linear regression analysis showed that a low GNRI was significantly associated with low lumbar spine bone mineral density (BMD) and T-score, and that a low ASM/height2 was significantly associated with low femoral neck BMD and T-score. A low vitamin D level was significantly associated with low femoral neck BMD and T-score and low total hip BMD and T-score. A high bone alkaline phosphatase (ALP) level was significantly associated with low femoral neck T-score and low total hip BMD and T-score. A low insulin-like growth factor-1 (IGF-1) was significantly associated with low total hip BMD and T-score. Conclusion: In the postmenopausal women who had undergone total thyroidectomy in this study, BMD was positively associated with GNRI, skeletal muscle mass index, and levels of vitamin D and serum IGF-1, and inversely associated with bone ALP level. Nutritional status, skeletal muscle mass index and bone turnover biomarkers can be used to early identify patients with a high risk of osteoporosis in this high-risk group.

scholarly journals Appendicular Skeletal Muscle Mass Index and Physiological Performance in Post-Menopausal Women with Total Thyroidectomy

2021 ◽  
Vol 11 (16) ◽  
pp. 7555
Author(s):  
Wei-Lun Wen ◽  
Hsiu-Chu Lin ◽  
Hui-Chen Yu ◽  
Yi-Pen Chen ◽  
Ching-Chao Liang ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Total Thyroidectomy ◽  
Postmenopausal Women ◽  
Muscle Mass ◽  
Gait Speed ◽  
Skeletal Muscle Mass ◽  
Handgrip Strength ◽  
Appendicular Skeletal Muscle ◽  
Skeletal Muscle Mass Index ◽  
Appendicular Skeletal Muscle Mass

Sarcopenia is prevalent in postmenopausal women but is inconclusive in total thyroidectomy and under levothyroxine replacement. We aim to analyze the determinants of sarcopenia and investigate the early detection of sarcopenia in this group. Fifty postmenopausal women with total thyroidectomy were measured for body composition via Dual-energy X-ray Absorptiometry (DXA) and Appendicular Skeletal Muscle mass divided by the height square (ASM/ht2). Handgrip strength and gait speed and Geriatric Nutritional Risk Index (GNRI) were calculated. Eight determinants associated with sarcopenia include GNRI (β, 0.042; 95% confidence interval (CI), 0.021 to 0.064), femoral neck BMD (β, 0.989; 95% CI, 0.049 to 1.929), TSH (β, 0.192; 95% CI, 0.027 to 0.357), and thyroglobulin Ab (0.657; 95% CI, 0.210 to 1.103) for ASM/height2; menopausal years (β, −3.112; 95% CI, −5.661 to −0.563) and ASM/height2 (β, 2.669; 95% CI, 1.073 to 4.265) for handgrip strength; and GNRI (β, 0.062; 95% CI, 0.019 to 0.105), T3 (β, −3.541; 95% CI, −7.019 to −0.063), and age (β, 0.043; 95% CI, 0.003 to 0.084) for gait speed. Our study confirmed a high prevalence of low skeletal muscle mass index in postmenopausal women with total thyroidectomy and revealed a number of determinants that could help early diagnosis and management this disease in daily clinical practice.

scholarly journals Influence of the appendicular skeletal muscle mass index on the bone mineral density of postmenopausal women

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Geise Ferreira da Cruz ◽  
Tatiana Mion Lunz ◽  
Tatielle Rocha de Jesus ◽  
Mariana Braga Costa ◽  
Camila Vilarinho Vidigal ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Skeletal Muscle ◽  
Bone Mass ◽  
Postmenopausal Women ◽  
Muscle Mass ◽  
Skeletal Muscle Mass ◽  
Mineral Density ◽  
Appendicular Skeletal Muscle ◽  
Skeletal Muscle Mass Index ◽  
Appendicular Skeletal Muscle Mass

Abstract Background The appendicular skeletal muscle mass index (ASMI) is an important risk indicator for osteoporosis because of the anatomical proximity and metabolic connection between muscle and bone mass. The present study investigated the relationship between ASMI and the bone mineral density (BMD) categories of postmenopausal women. Methods In this cross-sectional study with a probabilistic sample, sociodemographic, lifestyle, menopause time, anthropometric, and physical activity variables were collected. ASMI and BMD were assessed by dual-energy X-ray absorptiometry (DXA). Participants were grouped according to BMD values into normal density, osteopenia, and osteoporosis. Multivariate logistic regression models were applied to verify the influence of ASMI on BMD. Data were analyzed using the SPSS statistical software, version 22. The significance level for all tests was set at 5%. Results Of the 114 women analyzed, most were between 60 and 69.9 years of age (62.3%), on menopause for ≤19.0 (51.8%), self-declared brown race/color (49.1%), had < 4 years of education (41.2%), never smoked (69.0%) or drank alcohol (62.8%). Of these, 52.6% were classified as sufficiently active and 52.2% had regular sun exposure. Women with osteoporosis were older (p = 0.035), on menopause for a longer time (p = 0.011), underweight (p = 0.004), had adequate waist circumference (p = 0.017), and low ASMI values (p = 0.002). There was an association between the 1st tertile of ASMI and osteoporosis. However, after adjustments for age, race/color, and body mass index, the strength of association between BMD and ASMI was not maintained. Conclusions ASMI was not associated with the BMD of the postmenopausal women evaluated. Total body and muscle mass, in addition to bone mass, should be monitored during menopause treatment. Longitudinal studies must be conducted to elucidate the mechanisms and gaps in this relationship.

scholarly journals Skeletal Muscle Mass Index Is Positively Associated With Bone Mineral Density in Hemodialysis Patients

2020 ◽  
Vol 7 ◽  
Author(s):  
Kiyonori Ito ◽  
Susumu Ookawara ◽  
Yutaka Hibino ◽  
Sojiro Imai ◽  
Mariko Fueki ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Skeletal Muscle ◽  
Muscle Mass ◽  
Bone Mineral ◽  
Skeletal Muscle Mass ◽  
Hemodialysis Patients ◽  
Mineral Density ◽  
Skeletal Muscle Mass Index

Skeletal muscle mass is strongly correlated with total Hip BMD in premenopausal women

2016 ◽  
Author(s):  
Sara Lee ◽  
Hyun Sik Youm ◽  
Hye-Kyung Song ◽  
Kyung-Ah Jeong ◽  
Joung Sook Kim ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Muscle Mass ◽  
Skeletal Muscle Mass ◽  
Premenopausal Women ◽  
Strongly Correlated ◽  
Total Hip ◽  
Hip Bmd

Relationships between changes in the skeletal muscle mass index and number of days needed for independent gait after cardiac surgery

Physiotherapy ◽  
2015 ◽  
Vol 101 ◽  
pp. e1069 ◽  
Author(s):  
M. Nakajima ◽  
M. Morishita ◽  
S. Yuguchi ◽  
K. Saito ◽  
T. Matsuo ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Cardiac Surgery ◽  
Muscle Mass ◽  
Skeletal Muscle Mass ◽  
Skeletal Muscle Mass Index

scholarly journals Combining Amino Acid and Vitamin D Supplementation with Exercise Training Increases Skeletal Muscle Mass and Prevent Bone Mineral Density Loss in Participants with Low Muscle Mass

2017 ◽  
Vol 10 (2) ◽  
pp. 28
Author(s):  
Ha Cao Thi Thu ◽  
Satoshi Kurose ◽  
Yaeko Fukushima ◽  
Nana Takao ◽  
Natsuko Nakamura ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Skeletal Muscle ◽  
Vitamin D ◽  
Body Composition ◽  
Amino Acid ◽  
Muscle Mass ◽  
Skeletal Muscle Mass ◽  
Vitamin D Supplementation ◽  
Mineral Density ◽  
Supplement Group

This study evaluated the impact of exercise training with amino acid and vitamin D supplementation on muscle and bone mass in participants with low muscle volume. Twenty-nine Japanese participants (56-84 years old) were enrolled and assigned into the supplement (n=15) and non-supplement (n=14) groups. All participants underwent a 6-month exercise program. Supplements and nutrition support were provided to the participants in the supplement group for 12 weeks. Body composition and whole bone mineral density (BMD) were measured using dual energy x-ray absorptiometry. The outcomes, including body composition, whole BMD, and skeletal muscle mass index (SMI), were evaluated twice: pre- and post-intervention. The SMI was 6.51(6.28; 7.14) and 5.58 (5.24; 6.05) (kg/m2) in men and women, respectively. The average SMI change was 0.13% (-0.05%; 0.31%) and 2.33% (-0.88%; 5.48%); [mean (lower; upper quartile)]. The average BMD loss in the non-supplement group was -2.78%, and the BMD increased in the supplement group by 4.34%; there was an absolute difference between the two groups (p<0.05). After the intervention, serum myostatin was changed (p=0.001, non-supplement>supplement), serum vitamin D was increased (p=0.03; supplement>non-supplement), and BMD was maintained (p=0.03, supplement>non-supplement). There was a significant difference in the serum myostatin level at baseline and at 6-month in the non-supplement group, with a mean difference of 483.78 ng/ml (p=0.01). There was no significant improvement in the total lean mass, and handgrip strength. Resistance exercise combined with an amino acid supplement affects muscle and bone mass in the short-term intervention.

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