scholarly journals Vitamin D Deficiency and Oral Health: A Comprehensive Review

Nutrients ◽  
2020 ◽  
Vol 12 (5) ◽  
pp. 1471 ◽  
Author(s):  
João Botelho ◽  
Vanessa Machado ◽  
Luís Proença ◽  
Ana Sintra Delgado ◽  
José João Mendes
Keyword(s):  
Vitamin D ◽  
Oral Health ◽  
Alveolar Bone ◽  
Oral Pathology ◽  
Osteonecrosis Of The Jaw ◽  
Oral Cancers ◽  
Tooth Mineralization ◽  
Oral Development ◽  
Preclinical And Clinical Studies ◽  
Oral Conditions

Vitamin D (VD) levels have been gaining growing attention in Oral Health. During growth and adulthood, VD deficiency (VDD) is associated with a wide variety of oral health disorders, and impaired VD synthesis may expedite some of these conditions. In children, severe VDD can induce defective tooth mineralization, resulting in dentin and enamel defects. As a consequence, these defects may increase the risk of the onset and progression of dental caries. Further, VDD has been associated with higher prevalence of periodontitis and gingival inflammation, and several recent preclinical and clinical studies have unveiled potential pathways through which Vitamin D may interact with the periodontium. VDD correction through supplementation may contribute to a successful treatment of periodontitis; however, alveolar bone regeneration procedures performed in baseline VDD patients seem more prone to failure. Vitamin D may also be linked with some oral pathology entities such as certain oral cancers and events of osteonecrosis of the jaw. This review aims to provide comprehensive evidence of how VD levels should be considered to promote good oral health, and to summarize how VDD may hamper oral development and its role in certain oral conditions.

scholarly journals The Impact of Oral Health on Systemic Health: Current Challenges and Future Prospective

2018 ◽  
Vol 2 (3) ◽  
Author(s):  
Bhanupriya Mahant
Keyword(s):  
Infectious Disease ◽  
Primary Care ◽  
Oral Health ◽  
Dental Caries ◽  
Oral Pathology ◽  
Point Of View ◽  
Common Infectious Disease ◽  
Systemic Health ◽  
Oral Conditions ◽  
The Impact

Oral pathology is a broad topic, but this article will focus on the oral conditions that have an established or accepted relationship with systemic health: caries and the periodontal disease-gingivitis and periodontitis. Dental caries is probably the most common infectious disease across humanity. Primary anticipation of disease is the best move toward but often difficult to achieve. From a primary care point of view, it is vital that physicians and dentists augment collaboration and share in sequence that can impact the patient’s health. Optimization of patients’ physical condition is the aim of both the medical and dental professions. Key Words: Oral Health, Systemic Health, Dental.

scholarly journals Clinical Implications of Vitamin D in Oral Diseases- A Review

2021 ◽  
pp. 103-110
Author(s):  
Deepa Jatti Patil
Keyword(s):  
Vitamin D ◽  
Oral Health ◽  
Nutritional Deficiencies ◽  
Positive Outcomes ◽  
Oral Diseases ◽  
Tooth Mineralization ◽  
High Prevalence ◽  
Mother And Child ◽  
Systemic Health

Oral health is a reflection of systemic health. The various nutritional deficiencies not only affect the systemic health but also have an impact on oral health. The prevalence of Vitamin D deficiency (VDD) is rampant globally. Vitamin D (VD) is not only essential for skeletal growth during childhood and adulthood but has a great impact on oral tissues and odontogenesis. VDD has several implications on oral health from childhood to adulthood. VD can negatively influence the oral health of the mother and child and VD supplementation brings positive outcomes during and after pregnancy. In children, severe VDD can impair tooth mineralization, resulting in defects of enamel and dentin and predispose patients to caries. A remarkably high prevalence of periodontitis is seen in VDD and has implications on systemic health as well. A high prevalence of VDD is seen in oropharyngeal cancers. This review aims to provide the biological role of VD and its receptor, its implication on oral health and future strategies for targeted therapies in oral pathologies.

scholarly journals Vitamin D Deficiency and its Effects on Tooth Structure and pulpal changes

2021 ◽  
Vol 9 (F) ◽  
pp. 81-87
Author(s):  
Lingam Amara Swapna ◽  
Rasheed Abdulsalam
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Alveolar Bone ◽  
Bone Mineralization ◽  
Oral Intake ◽  
Sun Exposure ◽  
Tooth Structure ◽  
Beneficial Effects ◽  
Tooth Mineralization ◽  
Dentin Formation

Vitamin D is a steroid hormone that produced primarily by sunlight exposure or obtained from dietary sources, including supplements. The persons who are normally at risk of Vitamin D deficiency are those with scarce of sun exposure and diminished intestinal absorption or limited oral intake. Teeth are nothing but mineralized structure which is enclosed by alveolar bone and are developed by 3 different hard tissues such as dentin, enamel, and cementum. Vitamin D plays a predominant vital part in the tooth and bone mineralization, and it can result in rachitic tooth when the levels get unregulated. Studies suggest that Vitamin D deficiency causes hypocalcified dentin and delayed tooth eruption; thus, representing that Vitamin D has a crucial role in dentin formation as well. The beneficial effects of vitamin D on oral health are not only limited to the direct effects on the tooth mineralization but are also applied through ability to stimulate the production of anti-microbial peptides. In this article, we will briefly discuss the influence on Vitamin D level on the oral and pulpal health.

scholarly journals Medication-Related Osteonecrosis of the Jaw (MRONJ): Are Antiresorptive Drugs the Main Culprits or Only Accomplices? The Triggering Role of Vitamin D Deficiency

Nutrients ◽  
2021 ◽  
Vol 13 (2) ◽  
pp. 561
Author(s):  
Luca Dalle Carbonare ◽  
Monica Mottes ◽  
Maria Teresa Valenti
Keyword(s):  
Vitamin D ◽  
Clinical Condition ◽  
Case Series ◽  
Osteonecrosis Of The Jaw ◽  
First Case ◽  
Vitamin D Levels ◽  
Exposed Bone ◽  
Antiresorptive Drugs ◽  
Almost All

Osteonecrosis of the jaw (ONJ) is a severe clinical condition characterized mostly but not exclusively by an area of exposed bone in the mandible and/or maxilla that typically does not heal over a period of 6–8 weeks. The diagnosis is first of all clinical, but an imaging feedback such as Magnetic Resonance is essential to confirm clinical suspicions. In the last few decades, medication-related osteonecrosis of the jaw (MRONJ) has been widely discussed. From the first case reported in 2003, many case series and reviews have appeared in the scientific literature. Almost all papers concerning this topic conclude that bisphosphonates (BPs) can induce this severe clinical condition, particularly in cancer patients. Nevertheless, the exact mechanism by which amino-BPs would be responsible for ONJ is still debatable. Recent findings suggest a possible alternative explanation for BPs role in this pattern. In the present work we discuss how a condition of osteomalacia and low vitamin D levels might be determinant factors.

Oral Health and Nutrition

2020 ◽  
Author(s):  
Carole. A. Palmer ◽  
Zhangmuge Cheng
Keyword(s):  
Oral Health ◽  
Dental Caries ◽  
Periodontal Diseases ◽  
Oral Disease ◽  
Oral Diseases ◽  
Oral Infections ◽  
Surgeon General ◽  
Optimal Health ◽  
Health And Disease ◽  
Oral Conditions

Oral diseases are among the most prevalent diseases affecting global health. In his report on the crisis in oral disease in America, the Surgeon General warned that one cannot be truly healthy without oral health. Oral health means freedom from all oral health problems; tooth decay (dental caries), periodontal diseases, tooth loss, oral-facial pain, oral cancer and the effects of its treatment, oral infections, craniofacial birth defects and more. The relationships between oral conditions and systemic health and disease are many and synergistic, and most involve dietary and/or systemic nutritional factors. Diet and nutrition can play important roles in the etiology, prevention, and/or management of oral conditions, as they do in overall health and disease. Today, all health professionals and educators need to be aware of and consider oral issues and their possible diet/nutritional implications as a component of optimal health care and education. This review article provides a brief overview of how diet and nutrition impact and are impacted by oral conditions, and offers general guidelines and resources for providing meaningful interventions throughout the life cycle. This review contains 3 figures, 3 tables, and 57 references Key Words: biofilm, cariogenic, dental caries, dental plaque, ECC-early childhood caries, lactobacillus, mucositis, non-cariogenic, periodontal disease, Streptococcus mutans

scholarly journals Evaluation of oral conditions in patients with neurodegenerative diseases treated in geriatric centers

2016 ◽  
Vol 64 (1) ◽  
pp. 17-23
Author(s):  
Bruna Marjorie Dias FROTA ◽  
Sarah Nascimento HOLANDA ◽  
Fabrício Bitú SOUSA ◽  
Ana Paula Negreiros Nunes ALVES
Keyword(s):  
Elderly Patients ◽  
Neurodegenerative Diseases ◽  
Oral Pathology ◽  
Control Group ◽  
Oral Manifestations ◽  
Denture Stomatitis ◽  
Exact Test ◽  
Clinical Conditions ◽  
Oral Conditions ◽  
And Control

ABSTRACT Objective: To compare the general clinical conditions and oral alterations, and also evaluate the prosthesis, in subjects diagnosed with Alzheimer's disease (AD) or Parkinson's disease (PD), attended at two geriatric centers in the city of Fortaleza - Ceará. Methods: 70 patients were analyzed (between 57 to 91 years) with AD and PD, through evaluation of neurological medical records and oral clinical examination. Variables as sex, age, race, comorbidities, oral manifestations and prosthetic conditions were observed. A total of 20 elderly patients without neurological disease consisted the control group (CG). Fisher's exact test and Kruskal-Wallis were used as statistical analysis. Results: In both groups, blood hypertension was the most frequent comorbidity. As for the oral examination in the group with AD, it was observed that 54.2% had periodontal disease, 34.2% caries. Similar results were found in PD patients (31.4%; 22.8% - respectively). However, no difference was observed between the groups, as the systemic and oral manifestations in both geriatric centers (p> 0.05). Was identified more than half of the subjects (57.7%) using dentures, and 86.5% of these had become maladaptive, with some kind of defect. There was statistical difference in the presence of associated oral pathology, denture stomatitis, between dementia and control group (p = 0.0213). Conclusion: Elderly patients with AD and PD have poor oral health, as well as those without neurodegenerative diseases. However, have more defects and disorders associated with the use of removable dentures.

scholarly journals The relationship between oral conditions, masticatory performance and oral health-related quality of life in children

2013 ◽  
Vol 58 (9) ◽  
pp. 1070-1077 ◽  
Author(s):  
Taís de Souza Barbosa ◽  
Maria Claudia de Morais Tureli ◽  
Marinês Nobre-dos-Santos ◽  
Regina Maria Puppin-Rontani ◽  
Maria Beatriz Duarte Gavião
Keyword(s):  
Quality Of Life ◽  
Oral Health ◽  
Health Related Quality ◽  
Masticatory Performance ◽  
Related Quality ◽  
Health Related ◽  
Oral Conditions ◽  
The Relationship

scholarly journals Effect of Vitamin D on Canine Distalization and Alveolar Bone Density Using Multi-slice Spiral CT: A Randomized Controlled Trial

2019 ◽  
Vol 20 (12) ◽  
pp. 1430-1435
Author(s):  
Venith J Pulikkottil ◽  
Lakshmi Lakshmanan ◽  
Sanju T Varughese ◽  
Pavithra U Shamanna ◽  
Neeraj Goyal ◽  
...  
Keyword(s):  
Vitamin D ◽  
Randomized Controlled Trial ◽  
Bone Density ◽  
Alveolar Bone ◽  
Controlled Trial ◽  
Spiral Ct ◽  
Randomized Controlled ◽  
Canine Distalization

scholarly journals The combination of miacalcic, calcium lactate, and vitamin C as postextracted alveolar bone resorption inhibitor

2010 ◽  
Vol 43 (3) ◽  
pp. 141
Author(s):  
Sri Kentjananingsih
Keyword(s):  
Vitamin D ◽  
Bone Density ◽  
Bone Resorption ◽  
Vitamin C ◽  
Group Treatment ◽  
Alveolar Bone ◽  
Vitamin D Supplementation ◽  
Calcium Lactate ◽  
Control Group ◽  
Significant Difference

Background: Tooth extraction can cause alveolar resorption, and will reduce the denture retention. The process of bone resorption looks like the process of osteoporosis. Calcium and vitamin D supplementation is the rational therapy for minimizing bone loss. Miacalcic is the drug of choice for osteporotic patient. Purpose: This study is aimed to know whether the combination of miacalcic, calcium lactate, and vitamin C are effective in inhibiting post extracted alveolar resorption. Methods: Thirty three healthy postmenopausal women were chosen as samples and they were classified randomly into control group (without treatment), 1st experiment group (treatment was started 3 months post extraction), and 2nd experiment group (treatment was started at the 2nd day post extraction). The treatment was done by giving miacalcic nasal spray, calcium lactate 500 mg and vitamin C 100 mg tablets every morning in 10 days every month for 3 months. X-ray photo of the post extracted area were taken an hour, 3 months, and 6 months post-extraction. Results: After 6 month, there was significant difference in buccolingual thickness decreasing among three groups (p<0.05). The maximum mean difference of buccolingual thickness decreasing was 0.72 mm, between control and 2nd experiment groups. There was no significant difference about decreasing bone density among them (p>0.10). The maximum difference of the mean of density decreasing was 1,906 g/cm2/mm between control and 2nd experiment groups. The increasing density mostly occurred in the 2nd experiment group. Conclusion: The combination of miacalcic, calcium lactate, and vitamin C are effective for inhibiting alveolar resorption, although statistically there was no significant difference about bone density decreasing. The sooner this treatment is given the better result will be achieved.Latar belakang: Pencabutan gigi menyebabkan resorpsi tulang alveolaris, dan akan mengurangi retensi geligi tiruan. Proses resorpsi tulang alveol pada osteoporosis mirip dengan proses resorpsi tulang pada penyembuhan luka bekas pencabutan. Miacalcic adalah obat utama untuk penderita osteoporosis. Kalsium dan vitamin D merupakan terapi yang rasional untuk meminimalkan resorpsi tulang. tujuan: Membuktikan apakah kombinasi miacalcic, kalsium laktat, and vitamin C juga efektif menghambat resorpsi tulang alveol pasca pencabutan. Metode: Sampel 33 wanita postmenopause yang sehat, terbagi secara acak ke dalam kelompok kontrol (tanpa perlakuan), kelompok eksperimen 1 (perlakuan mulai 3 bulan pasca pencabutan) dan kelompok eksperimen 2 (perlakuan mulai hari kedua pasca pencabutan). Perlakuannya yaitu: pemberian miacalcic semprot hidung, tablet kalsium laktat 500 mg dan vitamin C 100 mg setiap pagi, 10 hari dalam sebulan, selama tiga bulan. Foto sinar-X dari regio pasca pencabutan dibuat satu jam, 3 bulan, dan 6 bulan pasca pencabutan. Hasil: 6 bulan pasca-cabut, ada beda bermakna perihal selisih tebal bukolingual tulang alveol antar ketiga kelompok (p<0,05). Rerata penurunan ketebalan ini maksimal sebanyak 0.72 mm, antara kelompok kontrol dan kelompok eksperimen 2. Penurunan kepadatan tulang antar ketiga kelompok tidak bermakna (p>0,10). Beda maksimum rerata kepadatan tulang antara kelompok kontrol dan kelompok eksperimen 2 sebesar 1,906 g/cm2/mm. Peningkatan kepadatan terbanyak dialami anggota kelompok eksperimen 2. Kesimpulan: Kombinasi miacalcic, kalsium laktat, vitamin C efektif menghambat resorpsi tulang alveolaris, walaupun secara statistik beda penurunan kepadatan tidak bermakna. Makin awal pemberian perlakuan, hasilnya akan lebih baik.

scholarly journals Task Force on Design and Analysis in Oral Health Research: Medication-Related Osteonecrosis of the Jaw

2018 ◽  
Vol 3 (3) ◽  
pp. 222-225 ◽  
Author(s):  
S. Ruggiero ◽  
D. Saxena ◽  
S. Tetradis ◽  
T. Aghaloo ◽  
E. Ioannidou
Keyword(s):  
Oral Health ◽  
Knowledge Transfer ◽  
Health Research ◽  
Patient Management ◽  
Task Force ◽  
Osteonecrosis Of The Jaw ◽  
Clinical Protocols

Knowledge Transfer Statement: This article discusses the proceedings of the conference organized by the Task Force on Design and Analysis in Oral Health Research on the understanding of the translational evidence on the etiology and pathogenesis of medication-related osteonecrosis of the jaw as well as the clinical protocols on patient management.

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