scholarly journals Development of Dietary Supplement Label Database in Italy: Focus of FoodEx2 Coding

Nutrients ◽  
2019 ◽  
Vol 12 (1) ◽  
pp. 89 ◽  
Author(s):  
Alessandra Durazzo ◽  
Emanuela Camilli ◽  
Laura D’Addezio ◽  
Raffaela Piccinelli ◽  
Angelika Mantur-Vierendeel ◽  
...  
Keyword(s):  
Dietary Supplements ◽  
Dietary Supplement ◽  
Marketing Strategies ◽  
Food Supplements ◽  
Context Information ◽  
Dietary Survey ◽  
New Production ◽  
Drug Companies ◽  
Italian Market ◽  
Production Technologies

The sector of food supplements is certainly varied and growing: an ever wider offer of new products is launched on the market every year. This is reflected in new reorganization of drug companies and new marketing strategies, in the adoption of new production technologies with resulting changes in dietary supplements regulation. In this context, information on composition reported in labels of selected dietary supplements was collected and updated for the development of a Dietary Supplement Label Database according to products’ availability on the Italian market and also including items consumed in the last Italian Dietary Survey. For each item, a code was assigned following the food classification and description system FoodEx2, revision 2. A total of 558 products have been entered into the database at present, trying to give a uniform image and representation of the major classes of food supplements, and 82 descriptors have been compiled. Various suggestions on how the number of FoodEx2 system descriptors could be expanded were noted during the compilation of the database and the coding procedure, which are presented in this article. Limits encountered in compiling the database are represented by the changes in the formulation of products on the market and therefore by the need for a constant database update. The database here presented can be a useful tool in clinical trials, dietary plans, and pharmacological programs.

scholarly journals Vitamin Dietary Supplement: Changes and Challenges with the New ANVISA Regulations

2021 ◽  
Author(s):  
Lucile Tiemi Abe-Matsumoto ◽  
Viviane de Paula Acosta Iglesia ◽  
Regina Sorrentino Minazzi-Rodrigues
Keyword(s):  
Vitamin D ◽  
Dietary Supplements ◽  
Dietary Supplement ◽  
Daily Intake ◽  
Fold Increase ◽  
Health Surveillance ◽  
Food Supplements ◽  
Extensive Discussion ◽  
The Impact ◽  
The Ideal

AbstractIn July 2018, the Brazilian National Health Surveillance Agency (Agência Nacional de Vigilância Sanitária, ANVISA, in Portuguese) published new regulations for food supplements, leading to changes both in the sales denomination and labeling statements, and in the composition of these products. Among dietary supplements, those containing vitamins are the most consumed by the population. The objective of the present work is to discuss the changes in the parameters established for the products containing vitamins, mainly in relation to the required and allowed concentrations of micronutrients, and to verify the impact of these changes for the population since the publication of the new standards. Until July 2018, vitamin-based products containing between 15% and 100% of the recommended daily intake (RDI) of these micronutrients were classified as vitamin supplements; above this dosage, they were considered medicines. The new legislation changed the minimum and maximum limits allowed for vitamin food supplements. Taking into account the maximum vitamin limits established for adults, the most relevant differences were the increase in these limits in a proportion of 100, 76 and 43 times in regarding vitamins E, B6 and C respectively, when compared to those previously established. For the required minimum limits, the major difference was observed for vitamin D, with a four-fold increase in its concentration. In conclusion, changes in legislation can influence the health of the population, so the ideal amounts of vitamin in supplements and the recommendation to consume these products require extensive discussion and reflection.

scholarly journals Dietary supplement use in elementary school children: a Japanese web-based survey

2021 ◽  
Vol 26 (1) ◽  
Author(s):  
Kazue Ishitsuka ◽  
Satoshi Sasaki ◽  
Hidetoshi Mezawa ◽  
Mizuho Konishi ◽  
Maki Igarashi ◽  
...  
Keyword(s):  
Dietary Supplements ◽  
Dietary Supplement ◽  
Sports Participation ◽  
Web Based ◽  
Mineral Supplements ◽  
Supplement Use ◽  
Health Related Behaviors ◽  
Health Related ◽  
Dietary Supplement Use ◽  
Frequency Of Sports Participation

Abstract Background A variety of dietary supplements are commercially available. However, the efficacy and safety of dietary supplement use in children are not well established. Understanding dietary supplement use is important for developing public health policy regarding dietary supplements. This study aimed to investigate the types of dietary supplements used and characteristics of dietary supplement users among Japanese elementary school children. Method We conducted a cross-sectional web-based questionnaire study. Dietary supplement use, socio-demographics, and health-related behaviors were assessed through mother-reported questionnaire. Types of dietary supplements were identified based on ingredient using product barcodes and brand names. Multivariate logistic regression analysis was conducted to investigate the socio-demographics and health-related behaviors associated with supplement use. Results Among 4933 children, 333 (6.8%) were identified as dietary supplement users. The most common supplement was amino acids or protein (1.4%), followed by n–3 fatty acids or fish oil (1.0%), probiotics (1.0%), multivitamins (0.9%), multivitamin-minerals (0.8%), and botanicals (0.8%). Overall, any dietary supplement use was significantly associated with the highest frequency of sports participation (odds ratio [OR], 2.58; 95% confidence interval [CI], 1.65–4.02), highest household income (OR, 1.87; 95% CI, 1.13–3.10), highest maternal educational level (OR, 1.82; 95% CI, 1.31–2.52), and male sex (OR, 1.38; 95% CI, 1.09–1.75). The highest frequency of sports participation was significantly associated with higher odds of use of amino acids or protein (OR, 6.06; 95% CI, 1.78–20.6) and multivitamins (OR, 3.56; 95% CI, 1.11–11.5), compared to the lowest frequency of sports participation. Conclusion This study showed that Japanese children primarily use non-vitamin, non-mineral supplements. Non-vitamin, non-mineral supplements should thus be included in future studies aimed at monitoring dietary supplement use. We also found that dietary supplement use in children was associated with sports participation. Guidelines for dietary supplement use for children, in particular sport participants, are needed.

Opportunities for digitalization of quality management systems

2021 ◽  
pp. 17-21
Author(s):  
S.V. Alexandrova ◽  
◽  
V.A. Vasiliev ◽  
M.N. Alexandrov ◽  
◽  
...  
Keyword(s):  
Quality Management ◽  
Digital Technologies ◽  
Iso 9001 ◽  
Management Systems ◽  
Design And Development ◽  
New Production ◽  
Quality Management Systems ◽  
Provision Of Services ◽  
Production Technologies ◽  
Monitoring And Measurement

In the context of digitalization, the functioning of the QMS necessitates the development and application of qualitatively new management technologies, as well as fundamentally new production technologies. Science is faced with the question of studying the main ways of developing the QMS, determining its place and role in modern conditions and realities, including the use of digital technologies. The article defines the sections of the QMS (GOST R ISO 9001-2015), in which digital technologies can and should be implemented: clause 8.3 Design and development of products and services, clause 8.4. Production of products and provision of services, p. 7.1.5 Resources for monitoring and measurement, p. 9.3. Management analysis.

scholarly journals Use of dietary supplements in pregnant women in relation to sociodemographic factors – a report from The Environmental Determinants of Diabetes in the Young (TEDDY) study

2013 ◽  
Vol 16 (8) ◽  
pp. 1390-1402 ◽  
Author(s):  
Carin Andrén Aronsson ◽  
Kendra Vehik ◽  
Jimin Yang ◽  
Ulla Uusitalo ◽  
Kristen Hay ◽  
...  
Keyword(s):  
Vitamin D ◽  
Pregnant Women ◽  
Dietary Supplements ◽  
Dietary Supplement ◽  
Maternal Age ◽  
Environmental Determinants ◽  
Supplement Use ◽  
The Usa ◽  
Dietary Supplement Use ◽  
Prospective Longitudinal

AbstractObjectivesThe aim of the present study was to examine the prevalence and associated factors of dietary supplement use, particularly supplements containing vitamin D and fatty acids, in pregnant women enrolled in a multi-national study.DesignThe Environmental Determinants of Diabetes in the Young (TEDDY) study is a prospective longitudinal cohort study. Maternal dietary supplement use was self-reported through questionnaires at month 3 to 4 postpartum.SettingSix clinical research centres; three in the USA (Colorado, Georgia/Florida and Washington) and three in Europe (Sweden, Finland and Germany).SubjectsMothers (n 7326) to infants screened for high-risk HLA-DQ genotypes of type 1 diabetes.ResultsNinety-two per cent of the 7326 women used one or more types of supplement during pregnancy. Vitamin D supplements were taken by 65 % of the women, with the highest proportion of users in the USA (80·5 %). Overall, 16 % of the women reported taking fatty acid supplements and a growing trend was seen in all countries between 2004 and 2010 (P < 0·0001). The use was more common in Germany (32 %) and the USA (24 %) compared with Finland (8·5 %) and Sweden (7·0 %). Being pregnant with the first child was a strong predictor for any supplement use in all countries. Low maternal age (<25 years), higher education, BMI ≥ 25·0 kg/m2 and smoking during pregnancy were factors associated with supplement use in some but not all countries.ConclusionsThe majority of the women used dietary supplements during pregnancy. The use was associated with sociodemographic and behavioural factors, such as parity, maternal age, education, BMI and maternal smoking.

scholarly journals Optimization of spectrophotometric method for determination nattokinase activity in dietary supplements

2020 ◽  
Vol 3 (2) ◽  
pp. 96-103
Author(s):  
Dieu Thu Nguyen Thi ◽  
Dung Hoang Viet ◽  
Hong Ngoc Nguyen Thi ◽  
Thanh An Vu Thi ◽  
Thanh Hoa Mac Thi ◽  
...  
Keyword(s):  
Quality Control ◽  
Reaction Time ◽  
Dietary Supplements ◽  
Dietary Supplement ◽  
Reaction Temperature ◽  
Spectrophotometric Method ◽  
Fibrinolytic Activity ◽  
Valuable Contribution ◽  
Label Product ◽  
Measured Activity

Nattokinase is an enzyme with a strong fibrinolytic activity that can be used for preventing thrombolytic diseases. The fibrinolytic activity of the Nattokinase in dietary supplements is determined by spectrophotometric method. In this study, the conditions of the assay were examined and finally optimized as pH: 8.5, reaction temperature: 40oC, and reaction time: 60 minutes. The proposed method was validated and successfully applied to determine the Nattokinase activity in 10 dietary supplements. The results showed that the proportion of measured activity compared to label product activity were within in the range 79.1 - 98.0%. The effect of herbal compounds and excipients on Nattokinase activity were also surveyed. From the evaluated results and application to commercial samples, this method will be a valuable contribution to quality control of dietary supplement products containing Nattokinase. &nbsp;

scholarly journals MATHEMATICAL DESCRIPTION OF THE DISTRIBUTION LOGISTICS PROCESSES OF CONSIGNMENT SELLER DIETARY SUPPLEMENT MANUFACTURING COMPANIES

2021 ◽  
Vol 24 (1) ◽  
pp. 39-42
Author(s):  
Szabolcs Szentesi ◽  
◽  
Béla Illés ◽  
Peter Tamas ◽  
◽  
...  
Keyword(s):  
Supply Chains ◽  
Shelf Life ◽  
Dietary Supplement ◽  
Mathematical Description ◽  
Food Supplements ◽  
Manufacturing Companies ◽  
Stock Level ◽  
Logistics Network ◽  
Distribution Logistics ◽  
Special Case

Consignment sales are a special case of supply chains, as the products are never the property of the seller, so the distribution logistics network and the logic of the structure of the products are radically different from those of normal supply chains. Another problem is that the products have a shelf life. The inventory mechanism (qmin; qmax) is most often used for the commissioned stocks of companies producing food supplements and when checking the central inventory, i.e. replenishment to the maximum stock level when a certain stock level is reached. There are several factors to consider when filling up commission stocks and reviewing them by period. With the mathematical correlations of these factors, it is possible to distribute the commissioned finished products optimally. The paper deals with this problem.

scholarly journals The Prevalence of Dietary Supplement Use Among Elementary, Junior High, and High School Students: A Nationwide Survey in Japan

Nutrients ◽  
2018 ◽  
Vol 10 (9) ◽  
pp. 1176 ◽  
Author(s):  
Etsuko Kobayashi ◽  
Chiharu Nishijima ◽  
Yoko Sato ◽  
Keizo Umegaki ◽  
Tsuyoshi Chiba
Keyword(s):  
High School ◽  
High School Students ◽  
Adverse Events ◽  
Dietary Supplements ◽  
Dietary Supplement ◽  
Parental Education ◽  
Junior High ◽  
The Internet ◽  
Supplement Use ◽  
Dietary Supplement Use

The prevalence of dietary supplement use, such as vitamins, minerals, or fish oil, has increased among children in Japan; however, whether children are using dietary supplements appropriately remains unclear. This study aimed to determine dietary supplement use among children. In August 2017, a nationwide internet preliminary survey of 265,629 mothers aged from 25 to 59 years old was undertaken. Of these, 19,041 mothers of children attending either elementary school, junior high school, or high school were selected. Among them, 16.4% were currently providing their children with dietary supplements and 5.2% had previously given dietary supplements to their children. The prevalence of dietary supplement use was higher in boys than in girls, and the prevalence increased according to their grade. A total of 2439 participants were eligible to undertake a targeted survey on dietary supplement use. Dietary supplements were being taken to maintain health, supplement nutrients, and enhance growth in both boys and girls, and many children (37.5%) were provided with vitamin and mineral supplements. Mothers mainly obtained information concerning dietary supplements via the internet, and supplements were purchased in drug stores or via the internet. The prevalence of dietary supplement use in mothers was 65.4% and may be associated with the prevalence rates in children. Some mothers reported adverse events (3.6%) in their children, such as stomachache, diarrhea, nausea and vomiting, and constipation. The cause-and-effect relationships for adverse events were not clear, but some children were given products for adults. Children are more influenced by dietary supplements compared to adults. To prevent adverse events due to inappropriate use, parental education concerning dietary supplements is essential.

scholarly journals National Athletic Trainers' Association Position Statement: Evaluation of Dietary Supplements for Performance Nutrition

2013 ◽  
Vol 48 (1) ◽  
pp. 124-136 ◽  
Author(s):  
Jackie L. Buell ◽  
Rob Franks ◽  
Jack Ransone ◽  
Michael E. Powers ◽  
Kathleen M. Laquale ◽  
...  
Keyword(s):  
Dietary Supplements ◽  
Dietary Supplement ◽  
Sport Participation ◽  
Athletic Trainers ◽  
Position Statement ◽  
Educational Process ◽  
Athletic Trainer ◽  
Federal State ◽  
Safety And Efficacy ◽  
National Athletic Trainers Association

Objectives To help athletic trainers promote a “food-first” philosophy to support health and performance, understand federal and sport governing body rules and regulations regarding dietary supplements and banned substances, and become familiar with reliable resources for evaluating the safety, purity, and efficacy of dietary supplements. Background The dietary supplement industry is poorly regulated and takes in billions of dollars per year. Uneducated athletes need to gain a better understanding of the safety, eligibility, and efficacy concerns associated with choosing to take dietary supplements. The athletic trainer is a valuable athletic team member who can help in the educational process. In many cases, athletic trainers are asked to help evaluate the legality, safety, and efficacy of dietary supplements. For this position statement, our mission is to provide the athletic trainer with the necessary resources for these tasks. Recommendations Proper nutrition and changes in the athlete's habitual diet should be considered first when improved performance is the goal. Athletes need to understand the level of regulation (or lack thereof) governing the dietary supplement industry at the international, federal, state, and individual sport-participation levels. Athletes should not assume a product is safe simply because it is marketed over the counter. All products athletes are considering using should be evaluated for purity (ie, truth in labeling), safety, and efficacy.

THE SYSTEM OF SUBSTANTIATION OF THE CHOICE OF THE WELL OPERATION METHOD BASED ON THE MATRIX OF APPLICABILITY OF OIL PRODUCTION TECHNOLOGIES

2020 ◽  
pp. 82-86
Author(s):  
M.I. Kuzmin ◽  
A.N. Bublik ◽  
P.S. Muzichuk ◽  
L.B. Rudnik ◽  
A.V. Sushkov ◽  
...  
Keyword(s):  
Boundary Conditions ◽  
Economic Effect ◽  
Oil Production ◽  
New Production ◽  
Total Cost Of Ownership ◽  
Total Cost ◽  
Cost Of Ownership ◽  
The Matrix ◽  
Exploration And Production ◽  
Production Technologies

An information system is proposed that uses a new complex methodology for choosing a method for well operation based on applicability criteria and boundary conditions for the parameters of mechanized productivity technologies. A mechanism for selecting technologies is presented, which consists of filtering the general register of technologies according to the selected parameters for assessing the total cost of ownership at the Company’s fields. The process of forming and updating the technology base, criteria of applicability and their boundary conditions is considered. Graphic materials illustrate the prototype of this system. The developed methodology will speed up the process of introducing new production technologies, which in turn will lead to a positive economic effect – a decrease in the total cost of ownership of equipment for oil production at the Exploration and Production Block.

Development of biotechnology and assessment of antitumor properties of dietary supplements of tissue origin on cell cultures

2021 ◽  
pp. 33-34
Author(s):  
Наталья Александровна Кольберг ◽  
Сергей Леонидович Тихонов ◽  
Наталья Валерьевна Тихонова ◽  
Светлана Александровна Леонтьева
Keyword(s):  
Dietary Supplements ◽  
Tumor Cells ◽  
Dietary Supplement ◽  
Cell Cultures ◽  
Mammalian Cells ◽  
Broiler Chickens ◽  
Cytotoxic Effect ◽  
Antitumor Properties ◽  
Tissue Origin ◽  
Mcf 7

Разработана технология БАД из фабрициевой сумки цыплят-бройлеров. Доказано, что полученная БАД на нарушает жизнеспособность клеток млекопитающих и не проявляет цитотоксических свойств на метаболизм здоровых клеток, что свидетельствует о ее безопасности. Доказан выраженный цитотоксический эффект БАД на опухолевые клетки линии MCF-7. The technology of dietary supplements from the factory bag of broiler chickens has been developed. It was proved that the obtained dietary supplement does not violate the viability of mammalian cells and does not exhibit cytotoxic properties on the metabolism of healthy cells, which indicates its safety. A pronounced cytotoxic effect of dietary supplements on MCF-7 tumor cells has been proven.

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