scholarly journals The Dietary Inflammatory Index and Chronic Lymphocytic Leukaemia in the MCC Spain Study

Nutrients ◽  
2019 ◽  
Vol 12 (1) ◽  
pp. 48
Author(s):  
José Carlos Flores ◽  
Esther Gracia-Lavedan ◽  
Yolanda Benavente ◽  
Pilar Amiano ◽  
Dora Romaguera ◽  
...  
Keyword(s):  
Chronic Lymphocytic Leukaemia ◽  
Chronic Inflammation ◽  
Lymphocytic Leukaemia ◽  
Positive Association ◽  
Future Research ◽  
P Value ◽  
Dietary Inflammatory Index ◽  
Significant Positive Association ◽  
Logistic Regression Models ◽  
Inflammatory Index

Chronic inflammation plays a role in the development of chronic lymphocytic leukaemia (CLL), and diet might modulate chronic inflammation. This study aims to evaluate the association between the dietary inflammatory index (DII®) and CLL. A total of 366 CLL cases and 1643 controls of the Spanish multicase-control (MCC) Spain study were included. The inflammatory potential of the diet was assessed using the energy-adjusted dietary inflammatory index (E-DII) based on 30 items from a validated semi-quantitative food frequency questionnaire. Odds ratios (OR) and 95% confidence intervals (CI) were estimated using logistic regression models controlling for potential confounders. Overall, a modest, non-statistically significant, positive association was observed between CLL and E-DII scores (OR for a one-unit increase in E-DII: 1.05 (CI 95%: 0.99, 1.12), p-value = 0.09 and by tertiles: ORT2vsT1: 1.20 (CI 95%: 0.90, 1.59); OR T3vsT1: 1.21 (CI 95%: 0.90, 1.62), p trend = 0.21). These results were independent from disease severity (p-het: 0.70), time from diagnosis (p-het: 0.67) and CLL treatment received (p-het: 0.56). No interactions were detected. In conclusion, the consumption of a diet with high pro-inflammatory components was not significantly associated with CLL. Changes towards a more pro-inflammatory dietary pattern in younger generations not included here warrant future research.

scholarly journals The association between dietary inflammatory index and gastric cancer: A case control study

2020 ◽  
Author(s):  
Ahmad Mujtaba Barekzai ◽  
Azadeh Aminianfar ◽  
Seyed Mohammad Mousavi ◽  
Ahmad Esmaillzadeh
Keyword(s):  
Gastric Cancer ◽  
Case Control Study ◽  
Dietary Assessment ◽  
Positive Association ◽  
Case Control ◽  
Dietary Inflammatory Index ◽  
Significant Positive Association ◽  
Inflammatory Index ◽  
Gastric Cancer Patients ◽  
Control Study

Abstract Background No report is available about diet-disease associations in the understudied region of Afghanistan. Although inflammatory potential of diet has been linked with several cancers, information about gastric cancer is scarce. This study aimed to investigate the relationship between dietary inflammatory index (DII) and odds of gastric cancer in Afghanistan. Methods In this hospital-based case-control study, we enrolled 90 newly-diagnosed cases of gastric cancer and 180 age (± 5) and sex-matched controls. All cases were pathologically confirmed gastric cancer patients, with no history of any type of other pathologically confirmed cancers. Controls were healthy individuals and relatives of patients in the hospital. Dietary assessment was done by a pre-tested food frequency questionnaire. DII was calculated based on energy-adjusted amounts of several foods and nutrients with inflammatory or anti-inflammatory potential, as introduced by earlier studies. Results Mean age of study participants was 54 years, of them 73% were males. After adjustment for age and sex, individuals in the highest tertile of DII were 2.47 times (95% CI: 1.31–4.66) more likely to have gastric cancer compared with those in the lowest tertile. Further adjustment for other potential confounders did not substantially affect the association; such that participants with the greatest DII had approximately 3.59 times (95% CI: 1.16, 11.02) increased odds of gastric cancer than those with the lowest adherence. Additional adjustment for BMI strengthened the association (OR: 3.75; 95% CI: 1.14–12.30). Conclusion We found a significant positive association between inflammatory potential of diet and risk of gastric cancer. Further studies with prospective nature are required to confirm this association.

scholarly journals Association of Dietary Inflammatory Index (DII) With the Risk of Poly Cystic Ovary Syndrome: a Case-control Study

2021 ◽  
Author(s):  
Parivash Kavei ◽  
Esmaeil Yousefi Rad ◽  
Soheila Akbari ◽  
Ebrahim Falahi ◽  
Mahnaz Mardani ◽  
...  
Keyword(s):  
Energy Intake ◽  
Case Control Study ◽  
Positive Association ◽  
Case Control ◽  
Control Group ◽  
P Value ◽  
Dietary Inflammatory Index ◽  
Inflammatory Index ◽  
Increased Risk ◽  
Control Study

Abstract Objective: The aim of this case-control study was to investigate the association between Dietary Inflammatory Index (DII) and PCOS risk in the 120 newly-diagnosed cases of PCOS and 120 healthy controls aged between 18-45 years in Khorramabad of Iran. Results: Energy intake was significantly more in PCOS patients (p=0.01) and these people were less active than control women (p=0.001). The mean ± SD of DII in PCOS patients was 0.4±2.09 while it was 0.45±1.92 in control group (p=0.001). There was a positive association between increasing DII score and the risk of PCOS with the OR of 2.41(1.15, 5.02) in the crude model when we compared the fourth quartile with the lowest one. This association was still significant in several models after adjusting for age and energy intake in the model 1 (P- value for trend=0.001), in the second model and after adjusting for the level of activity, education, and family history of PCOS along with the first model (P- value for trend 0.003), and finally after additional adjustment for BMI in model 3 (P- value for trend 0.003). Results of present study showed that consuming more pro-inflammatory diets with higher DII scores are associated with increased risk of PCOS.

scholarly journals "Association Between Dietary Inflammatory Index (DII) and Risk of Irritable Bowel Syndrome: A Case-Control Study"

2021 ◽  
Author(s):  
Elham Eslampour ◽  
Koroush Ghanadi ◽  
Vahideh Aghamohammadi ◽  
Alireza Moayed Kazemi ◽  
Rasool Mohammadi ◽  
...  
Keyword(s):  
Positive Association ◽  
Continuous Variable ◽  
Dietary Factors ◽  
Inflammatory Factors ◽  
Healthy Controls ◽  
Dietary Inflammatory Index ◽  
Logistic Regression Models ◽  
Inflammatory Index ◽  
Irritable Bowel ◽  
Age And Sex

Abstract BackgroundPathophysiology of IBS is not well recognized; however, several studies have shown the possible relationship between diet and risk of IBS. We assessed the ability of the dietary inflammatory index (DII) to predict the risk of IBS.MethodsThe subjects were 155 IBS cases and 310 age- and sex-matched healthy controls. IBS was recognized using the Rome IV criteria. DII score was computed based on dietary intake using a 168-item FFQ. The FFQ was analyzed using Nutritionist ІV. The DII score was calculated based on energy-adjusted amounts of nutrients using residual method. Logistic regression models were used to estimate multivariable odds ratios (ORs).ResultsThe mean DII score was significantly higher among IBS patients in comparison to healthy controls (0.78 ± 2.22 vs. -0.39 ± 2.27). In crude model, increase in DII as continuous variable was associated with a significant increase in the risk of IBS (OR (95% CI): 1.26 (1.1-15.38)). Furthermore, the association remained significant even after adjusting for age and sex (OR (95% CI): 1.28 (1.1-17.41)) and after multivariate adjustment (OR (95% CI): 1.38 (1.2-1.56)). In crude, age and sex adjusted and multivariate-adjusted models subjects in fourth quartile of DII had higher OR in comparison to subjects in first quartile. ConclusionsThe results of this study showed a possible positive association between a pro-inflammatory diet and the risk of IBS. Thus, encouraging intake of more anti-inflammatory dietary factors and reducing intake of pro-inflammatory factors may be a strategy for reducing risk of IBS.

scholarly journals “Association between dietary inflammatory index (DII) and risk of irritable bowel syndrome: a case-control study”

2021 ◽  
Vol 20 (1) ◽  
Author(s):  
Elham Eslampour ◽  
Koroush Ghanadi ◽  
Vahideh Aghamohammadi ◽  
Alireza Moayed Kazemi ◽  
Rasool Mohammadi ◽  
...  
Keyword(s):  
Positive Association ◽  
Continuous Variable ◽  
Dietary Factors ◽  
Inflammatory Factors ◽  
Healthy Controls ◽  
Dietary Inflammatory Index ◽  
Logistic Regression Models ◽  
Inflammatory Index ◽  
Irritable Bowel ◽  
Age And Sex

Abstract Background Pathophysiology of IBS is not well recognized; however, several studies have shown the possible relationship between diet and risk of IBS. We assessed the ability of the dietary inflammatory index (DII) to predict the risk of IBS. Methods The subjects were 155 IBS cases and 310 age- and sex-matched healthy controls (aged ≥18 years). The participants were recruited from June, 2019 to March, 2020. IBS was recognized using the Rome IV criteria. DII score was computed based on dietary intake using a 168-item FFQ. The DII score was calculated based on energy-adjusted amounts of nutrients using residual method. Logistic regression models were used to estimate multivariable odds ratios (ORs). Results The mean DII score was significantly higher among IBS patients in comparison to healthy controls (0.78 ± 2.22 vs. − 0.39 ± 2.27). In crude model, increase in DII as continuous variable was associated with a significant increase in the risk of IBS (OR (95% CI): 1.26 (1.1–15.38)). Furthermore, the association remained significant even after adjusting for age and sex (OR (95% CI): 1.28 (1.1–17.41)) and after multivariate adjustment (OR (95% CI): 1.38 (1.2–1.56)). In crude, age and sex adjusted and multivariate-adjusted models subjects in fourth quartile of DII had higher OR in comparison to subjects in first quartile. Conclusions This study showed a possible positive association between a pro-inflammatory diet and the risk of IBS. Thus, encouraging intake of more anti-inflammatory dietary factors and reducing intake of pro-inflammatory factors may be a strategy for reducing risk of IBS.

scholarly journals Association between dietary inflammatory index and components of metabolic syndrome

2019 ◽  
Vol 12 (1) ◽  
pp. 27-34
Author(s):  
Sima Ghorabi ◽  
Alireza Esteghamati ◽  
Kamal Azam ◽  
Elnaz Daneshzad ◽  
Omid Sadeghi ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Density Lipoprotein ◽  
Positive Association ◽  
Cross Sectional Study ◽  
Dietary Intakes ◽  
Dietary Inflammatory Index ◽  
Significant Positive Association ◽  
Cross Sectional ◽  
Inflammatory Index ◽  
Study Participants

Introduction: Limited data are available on the association of Dietary Inflammatory Index (DII) with metabolic syndrome (MetS) and its components. The present study was conducted to investigate the association of DII with MetS and its components among Iranian adults. <br /> Methods: A total of 404 subjects, aged 18 years or older, were included in the current cross-sectional study. We used a validated and reliable 147-item food frequency questionnaire (FFQ) to assess dietary intakes. Fasting blood sample was obtained to quantify glycemic indicators and lipid profile. MetS was defined based on the guidelines of the National Cholesterol Education Program Adult Treatment Panel III (ATP III). <br /> Results: Mean age of study participants was 38.20 ± 9.55 years. No significant association was found between DII and odds of MetS (odds ratio [OR]: 0.92, 95% CI: 0.48-1.76). In terms of MetS components, a significant positive association was seen between DII scores and reduced levels of high-density lipoprotein cholesterol (HDL-C) (OR: 2.29, 95% CI: 1.32-3.97); such that after controlling for energy intake, demographic variables and BMI, participants in the highest category of DII had 2.71 times greater odds for having reduced levels of HDL-C (OR: 2.71, 95% CIs: 1.34, 5.47). There was no other significant association between other components of MetS and DII scores either before or after adjusting for confounding variables.<br /> Conclusion: We observed no significant association between DII and odds of MetS. However, higher score of DII was associated with lower levels of HDL.

Association between dietary inflammatory index and cardiometabolic risk factors among Brazilian adolescents: results from a national cross-sectional study

2021 ◽  
pp. 1-24
Author(s):  
Pâmela Ferreira Todendi ◽  
Rafaela Salla ◽  
Nitin Shivappa ◽  
James R. Hebert ◽  
Julianna Ritter ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiometabolic Risk ◽  
Positive Association ◽  
Dietary Factors ◽  
Cardiometabolic Risk Factors ◽  
Model Assessment ◽  
Dietary Inflammatory Index ◽  
Cardiovascular Risks ◽  
Cross Sectional ◽  
Inflammatory Index

Abstract Dietary factors play a role in modulating chronic inflammation and in the development of cardiovascular disease. We aimed to investigate the association between the dietary inflammatory index (DII) and cardiometabolic risk factors among adolescents.A total of 31,684 Brazilian adolescents (12–17 years), from the Study of Cardiovascular Risks in Adolescents (ERICA) were included. Dietary intake was assessed using a 24-hour dietary recall. The E-DII (energy-adjusted)score was calculated based on data for 25available nutrients. The anthropometric profile, blood pressure, lipid profile, glucose, Homeostatic Model Assessment for Insulin Resistance (HOMA-IR), and glycated hemoglobin were measured. Poisson regression models were used to examine the associations between sex-specific quartiles of the E-DII and cardiometabolic risk factors. In the energy-adjusted models, when comparing a high pro-inflammatory diet (quartile 4) withananti-inflammatory diet (quartile 1), there was a positive association with high HOMA-IR among boys(prevalence ratios (PR)Q4=1.37, 95%CI: 1.04–1.79); and with high fasting glucose (PRQ4 = 1.96, 95%CI: 1.02–3.78), high triglycerides (PRQ4 = 1.92, 95%CI: 1.06–3.46),low HDL-c (PRQ4 = 1.16, 95%CI: 1.02–1.32) and high LDL-c (PRQ4 = 1.93, 95%CI: 1.12–3.33) among girls. Additionally, a moderately pro-inflammatory diet was positively associated with high HOMA-IR (PRQ2 = 1.14, 95%CI: 1.02–1.29) among girls, and high total cholesterol (PRQ3 = 1.56, 95%CI: 1.20–2.01) among boys.In conclusion, this study provides new evidence on the association between inflammatory diets with cardiometabolic risk factors among adolescents.

scholarly journals Anthropometric indices are associated with LDL cholesterol in postmenopausal Javanese women

2014 ◽  
Vol 13 (2) ◽  
pp. 124-127
Author(s):  
Syaefudin Ali Akhmad
Keyword(s):  
Postmenopausal Women ◽  
Ldl Cholesterol ◽  
Total Cholesterol Level ◽  
Lipid Level ◽  
Medical Science ◽  
Positive Association ◽  
Abdominal Circumference ◽  
P Value ◽  
Anthropometric Indices ◽  
Significant Positive Association

Introduction: Lipid abnormalities are seen to be linked lack of physical activity, obesity, metabolic syndrome and diabetes mellitus. Postmenopausal women experience the changes of body composition by increasing the visceral fat. The study was aimed to explore relationship between anthropometric indices and lipid level in postmenopausal Javanese women. Methods: This cross sectional study included 34 healthy postmenopausal Javanese women, age range between 46-59 years, from Dusun Trukan, Karanggede dan Marangan Prambanan subdistrict, Sleman district. Anthropometric measurements were carried following standard procedure. Appropriate statistical tools were used to analyze data using SPSS Version 17. A p value <0.05 was taken as level of significance. Results: Abdominal circumference showed significant positive association with LDL level (r=0.289, p=0.049) but not with triglyceride, HDL level and total cholesterol level. BMI also showed significant positive association with LDL level (r=0.336, p=0.026) but not with other variables. Conclusion: The data concluded that abdominal circumference and BMI are positively association with LDL cholesterol but not with other components of the lipid profile in Javanese postmenopausal women. Further studies, however, needed to warranted to understand the causal relationship involving large number of subjects multiple centres. DOI: http://dx.doi.org/10.3329/bjms.v13i2.18293 Bangladesh Journal of Medical Science Vol.13(2) 2014 p.124-127

scholarly journals Dietary Inflammatory Index and S-Klotho Plasma Levels in Middle-Aged Adults

Nutrients ◽  
2020 ◽  
Vol 12 (2) ◽  
pp. 281 ◽  
Author(s):  
Lucas Jurado-Fasoli ◽  
Manuel J. Castillo ◽  
Francisco J. Amaro-Gahete
Keyword(s):  
Plasma Levels ◽  
Solid Phase ◽  
Positive Association ◽  
Enzyme Linked Immunosorbent Assay ◽  
Dietary Inflammatory Index ◽  
Middle Aged ◽  
Close Link ◽  
Food Frequency ◽  
Inflammatory Index ◽  
Middle Aged Adults

Background: Soluble Klotho (S-Klotho) is an aging suppressor with a close link with inflammation. However, it is still unknown whether the dietary inflammatory potential is associated with S-Klotho plasma level. We aimed to investigate the association of the Dietary Inflammatory Index (DII) with S-Klotho plasma levels in middle-aged sedentary adults. Methods: 73 middle-aged sedentary adults (40–65 years old) participated in the present study. DII was determined from 28 dietary items obtained by 24 h recalls and food frequency questionnaires. The S-Klotho plasma levels were measured using a solid-phase sandwich enzyme-linked immunosorbent assay. Results: a weak positive association was observed between DII and S-Klotho plasma levels (β = 52.223, R2 = 0.057, p = 0.043), which disappeared after controlling for body mass index (p = 0.057). Conclusions: A pro-inflammatory dietary pattern measured with the DII was slightly and positively associated with S-Klotho plasma levels in middle-aged sedentary adults.

scholarly journals Association between dietary inflammatory index and prostate cancer among Italian men

2014 ◽  
Vol 113 (2) ◽  
pp. 278-283 ◽  
Author(s):  
Nitin Shivappa ◽  
Cristina Bosetti ◽  
Antonella Zucchetto ◽  
Maurizio Montella ◽  
Diego Serraino ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cancer Risk ◽  
Smoking Status ◽  
Wide Spectrum ◽  
Prostate Cancer Risk ◽  
Dietary Inflammatory Index ◽  
Logistic Regression Models ◽  
Inflammatory Index ◽  
History Of ◽  
Relationship Of

Previous studies have shown that various dietary components may be implicated in the aetiology of prostate cancer, although the results remain equivocal. The possible relationship of inflammation derived from dietary exposures with prostate cancer risk has not been investigated. We examined the ability of a newly developed dietary inflammatory index (DII) to predict prostate cancer risk in a case–control study conducted in Italy between 1991 and 2002. A total of 1294 patients aged < 75 years with incident, histologically confirmed carcinoma of the prostate served as cases. A total of 1451 subjects aged < 75 years who were admitted to the same hospitals as cases for a wide spectrum of acute, non-neoplastic conditions served as controls. The DII was computed based on dietary intake assessed using a previously validated seventy-eight-item FFQ. Logistic regression models were used to estimate multivariable OR adjusted for age, study centre, years of education, social class, BMI, smoking status, family history of prostate cancer and total energy intake. Men with higher DII scores had a higher risk of prostate cancer when analysed using the DII as both continuous (OR 1·06, 95 % CI 1·00, 1·13) and categorical, i.e. compared with men in the lowest quartile of the DII, men in the third and fourth quartiles were at elevated risk (ORQuartile 3 v. 1 1·32, 95 % CI 1·03, 1·69 and ORQuartile 4 v. 1 1·33, 95 % CI 1·01, 1·76; Ptrend= 0·04). These data suggest that a pro-inflammatory diet, as indicated by the increasing DII score, is a risk factor of prostate cancer in Italian men.

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