scholarly journals Validation of Surrogate Anthropometric Indices in Older Adults: What Is the Best Indicator of High Cardiometabolic Risk Factor Clustering?

Nutrients ◽  
2019 ◽  
Vol 11 (8) ◽  
pp. 1701 ◽  
Author(s):  
Robinson Ramírez-Vélez ◽  
Miguel Ángel Pérez-Sousa ◽  
Mikel Izquierdo ◽  
Carlos A. Cano-Gutierrez ◽  
Emilio González-Jiménez ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Waist Circumference ◽  
Cardiometabolic Risk ◽  
Characteristic Curve ◽  
Risk Index ◽  
International Diabetes Federation ◽  
Density Lipoprotein ◽  
Screening Tools ◽  
Anthropometric Indices ◽  
Cross Sectional

The present study evaluated the ability of five obesity-related parameters, including a body shape index (ABSI), conicity index (CI), body roundness index (BRI), body mass index (BMI), and waist-to-height ratio (WtHR) for predicting increased cardiometabolic risk in a population of elderly Colombians. A cross-sectional study was conducted on 1502 participants (60.3% women, mean age 70 ± 7.6 years) and subjects’ weight, height, waist circumference, serum lipid indices, blood pressure, and fasting plasma glucose were measured. A cardiometabolic risk index (CMRI) was calculated using the participants’ systolic and diastolic blood pressure, triglycerides, high-density lipoprotein and fasting glucose levels, and waist circumference. Following the International Diabetes Federation definition, metabolic syndrome was defined as having three or more metabolic abnormalities. All surrogate anthropometric indices correlated significantly with CMRI (p < 0.01). Receiver operating characteristic curve analysis of how well the anthropometric indices identified high cardiometabolic risk showed that WtHR and BRI were the most accurate indices. The best WtHR and BRI cut-off points in men were 0.56 (area under curve, AUC 0.77) and 4.71 (AUC 0.77), respectively. For women, the WtHR and BRI cut-off points were 0.63 (AUC 0.77) and 6.20 (AUC 0.77), respectively. In conclusion, BRI and WtHR have a moderate discriminating power for detecting high cardiometabolic risk in older Colombian adults, supporting the idea that both anthropometric indices are useful screening tools for use in the elderly.

scholarly journals KADAR ASAM URAT SERUM DAN KOMPONEN SINDROM METABOLIK

2016 ◽  
Vol 20 (3) ◽  
pp. 227
Author(s):  
MI Diah P ◽  
Banundari Rachmawati ◽  
Purwanto AP
Keyword(s):  
Blood Pressure ◽  
Waist Circumference ◽  
Systolic Blood Pressure ◽  
Diastolic Blood Pressure ◽  
Elevated Serum ◽  
International Diabetes Federation ◽  
Correlation Coefficients ◽  
Cross Sectional ◽  
Long Term Study ◽  
Student’S T

The incidence of metabolic syndrome (MetS) is significantly increasing. The elevated serum uric acid (SUA) level is correlated with the metabolic risk of cardiovascular. The relationship between SUA levels and components of MetS has been inconsistent. The aim of this study was to know the correlation between SUA level and component of MetS by analyzng. This study was a cross-sectional design conducted on healthy people at the Medical Check Up (MCU) Clinic, Dr. Moewardi Hospital, Surakarta from June 2012 until February 2013. MetS was defined according to the 2005 International Diabetes Federation (IDF) criteria. The statistical analysis was done by Student’s T test, Pearson or Spearman correlation coefficients. The researchers considered p<0.05 as statistically significant with a 95% confidence interval. A total of 80 healthy subjects, (range 19–57 years) were enrolled into this study. MetS was diagnosed in 40 persons where men (62.5%) were more than women and the non-MetS in women (62.5%) were more than men. In this study, a positive correlation was found between SUA and systolic blood pressure, diastolic blood pressure and waist circumference (Pearson r=0.354, 0.495, 0.399, respectively, p<0.05) in women, but not in men. The SUA was positively correlated with systolic blood pressure, diastolic blood pressure and waist circumference, particularly in women. A long term study is needed to investigate the consequence of increasing the SUA level in metabolic disorders and hormonal influences as well.

Comparative Studies on Hormonal Changes and Metabolic Syndrome in Perimenopausal and Premenopausal Igbo Women in Enugu Metropolis Nigeria: A Cross-sectional Study

2019 ◽  
Vol 15 (4) ◽  
pp. 284-294
Author(s):  
Chinwe Ifeoma Ikegwuonu ◽  
Uchendu Kingsley Ikenna ◽  
Okonkwo Innocent Nwabueze ◽  
Mba Chika Betina ◽  
Maduka Ignatius Chukwudi ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Metabolic Syndrome ◽  
Waist Circumference ◽  
International Diabetes Federation ◽  
Premenopausal Women ◽  
World Health ◽  
Categorical Variables ◽  
Hormonal Changes ◽  
Cross Sectional ◽  
Perimenopausal Women

Background and Objective: Few studies have focused on the epidemiology of perimenopausal syndrome, and its prevalence in African women is concerningly high. This study investigated selected biochemical parameters, hormonal changes, and possible metabolic syndrome (MetS) in perimenopausal and premenopausal women among Igbo women in Enugu, Southeast of Nigeria. Methods: This study was conducted between March 2018 and November 2018. A total of 200 apparently healthy women, comprising 120 perimenopausal women (mean age 50 years) and 80 premenopausal women (mean age 35 years), living in Enugu, were randomly recruited for this study. Anthropometric indices (blood pressure, waist circumference, weight, and height) of these women were measured. Fasting blood samples were collected and used for measurement of luteinizing hormone (LH), estradiol (E2), follicle stimulating hormone (FSH), fasting plasma glucose (FPG), and lipid profile using standard methods. MetS in the perimenopausal and premenopausal women was observed using three different criteria: the National Cholesterol Education Program- Adult Treatment Panel 111 (NCEP-ATP 111), the World Health Organization (WHO), and International Diabetes Federation (IDF). Student’s t-test and Chi-square were used to compare continuous and categorical variables. Results: There were significantly (p<0.05) higher values of blood pressure (systolic and diastolic), FPG, waist circumference, LH, FSH, total cholesterol, and LDL-C, but significantly (p<0.05) lower values of estradiol in perimenopausal women as compared to premenopausal women. The incidence of MetS was higher in perimenopausal women as compared to premenopausal women in all the three criteria studied. Interpretation and Conclusion: Perimenopausal women have a higher risk for the development of metabolic syndrome-associated diseases than premenopausal women.

scholarly journals The Gender-Specific Effect of Subcutaneous and Visceral Adipose Tissues on Cardiometabolic Risk in a Chinese Population

2021 ◽  
Author(s):  
Qiong Wu ◽  
Qiannan Chen ◽  
Qingguo Lv ◽  
Sun Xiaohui ◽  
Chen Dai ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Adipose Tissue ◽  
Cardiometabolic Risk ◽  
Biological Effects ◽  
Density Lipoprotein ◽  
Specific Effect ◽  
Cross Sectional ◽  
Low Hdl ◽  
Visceral Adipose ◽  
Gender Specific

Abstract BackgroundPrevious studies demonstrated that visceral adipose tissue (VAT) contributed to increased risks for multiple cardiometabolic factors. However, the effects of subcutaneous adipose tissue (SAT) were controversial. Furthermore, their effects were varied across sexes. The aim of this study was to examine the gender-specific effects of VAT, SAT, and VAT/SAT ratio on cardiometabolic risk factors. Methods1388 eligible subjects were recruited from a metabolic syndrome cross-sectional study in China. Areas of abdominal VAT and SAT were determined by nuclear magnetic resonance imaging (MRI). Multiple logistic regression was used to calculate the odds ratios (OR) and 95% confidence intervals (95%CI). ResultsSAT, VAT, and VAT/SAT ratio had significant age-adjusted, positive correlations with body mass index (BMI), waist circumference (WC), waist-to-hip ratio (WHR), systolic blood pressure (SBP), diastolic blood pressure (DBP), fasting plasma glucose (FPG), total triglycerides (TG), and inverse correlations with high-density lipoprotein cholesterol (HDL-C) except VAT/SAT ratio with FPG in men. After additional controlled by BMI, consistent results were found in VAT and VAT/SAT ratio except for VAT with FPG, however, women showed significant inverse correlations between SAT and SBP, DBP and TG. Higher SAT exhibited a significantly reduced risk for type 2 diabetes (T2D) in women, the ORs in third quartile (Q3) and fourth quartile (Q4) group were 0.3 (95% CI: 0.13-0.74) and 0.19 (95% CI: 0.07-0.54). Men had higher ORs of VAT, VAT/SAT ratio than women in higher TG, low HDL-C, and hypertension while the ORs of VAT/SAT ratio in men were lower than women in T2D. Conclusions SAT exhibited a beneficial effect on T2D. VAT and VAT/SAT ratio linked increased risks for high TG, low HDL-C, and hypertension, with men had a more pronounced effect than women. Distribution of abdominal fat associates with its biological effects.

scholarly journals Novel and traditional anthropometric indices for identifying metabolic syndrome in non-overweight/obese adults

2021 ◽  
Vol 18 (1) ◽  
Author(s):  
Lihong Wu ◽  
Wenhua Zhu ◽  
Qiaohua Qiao ◽  
Lijuan Huang ◽  
Yiqi Li ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Characteristic Curve ◽  
Screening Method ◽  
Density Lipoprotein ◽  
Shape Index ◽  
Volume Index ◽  
Binary Logistic Regression Analysis ◽  
Obese People ◽  
Anthropometric Indices ◽  
Cross Sectional

Abstract Background Metabolic syndrome (MetS) in non-overweight/obese people is insidiously associated with cardiovascular disease. Novel anthropometric indices can reflect central obesity better than the traditional anthropometric indices. Therefore, we hypothesize that these newly developed anthropometric indices can better identify MetS in non-overweight/obese people than conventional indices. Methods Cross-sectional data of sociodemographic, biochemical and anthropometric indices were collected from 2916 non-overweight/obese Chinese people. A body shape index (ABSI), body roundness index (BRI), waist-to-height ratio (WHtR), weight-adjusted-waist index (WWI) and abdominal volume index (AVI) were calculated. Partial correlation analysis was used to clarify the correlation between anthropometric indices and MetS variables. Binary logistic regression analysis was applied to assess the association between anthropometric indices and MetS and its components. Receiver-operating characteristic curve was used to identify the diagnostic ability of anthropometric indices for MetS and its components. The area under curve (AUC) difference between WHtR and each new anthropometric index was compared in pairs. Results After adjusting for covariates, AVI had the optimal ability of identifying MetS (AUC: 0.743 for male, 0.819 for female) and the strongest correlation with high-density lipoprotein cholesterol (HDL-C) (coe: − 0.227 for male, − 0.207 for female) and the highest odds rations (OR) with low HDL-C group (male: OR = 1.37, female: OR = 1.55). The WHtR was comparable to BRI in assessing MetS (AUC: 0.739 for male, 0.817 for female). WHtR or BRI could also well identify hypertension (AUC: 0.602 for male, 0.688 for female) and dysglycemia (AUC: 0.669 for male, 0.713 for female) and female’s high triglyceride level (AUC 0.712). The recognition ability of the two was equivalent. The ability of ABSI and WWI to identify MetS was weak. Conclusions AVI is the optimal anthropometric indices to identify MetS in non-overweight/obese Chinese adults. BRI and WHtR can also be considered as discriminators, while ABSI and WWI are weak discriminators. WHtR is easy to measure. So, it is recommended as an early preliminary screening method for the MetS in non-overweight/obese people.

Determining the Waist Circumference Cut off which Best Predicts the Metabolic Syndrome components in urban Africans: The SABPA study

2011 ◽  
Vol 119 (10) ◽  
pp. 599-603 ◽  
Author(s):  
J. Prinsloo ◽  
L. Malan ◽  
J. de Ridder ◽  
J. Potgieter ◽  
H. Steyn
Keyword(s):  
Blood Pressure ◽  
Metabolic Syndrome ◽  
Waist Circumference ◽  
International Diabetes Federation ◽  
Density Lipoprotein ◽  
The Metabolic Syndrome ◽  
Sub Saharan ◽  
The Relationship ◽  
Larger Sample ◽  
Metabolic Syndrome Components

AbstractVarious studies have shown that the relationship between waist circumference (WC) and abdominal obesity is age, gender as well as ethnicity-dependent. WC criteria for Sub Saharan Africans have not been defined by the International Diabetes Federation (IDF). The aim was to determine which WC cut off best predicted Metabolic Syndrome (MetS) in a group of urban African teachers (80 males and 93 females). We determined sphygmomanometer blood pressure, WC, glucose, high density lipoprotein cholesterol (HdL) and triglyceride (TRIG) values. The males′ MetS profile was less favourable as their glucose, TRIG and blood pressure levels were higher than the proposed cut off for MetS. The females could be classified as obese, based on their mean BMI (32.78±6.36) and WC (93.48±15.68). Receiver operating characteristic (ROC) WC cut offs of 90, 91, 94 and 96 cm for the respective MetS components in males (blood pressure, HdL, glucose and TRIG) were suggested. In the females, cut offs of 92, 98, 94 and 94 cm for TRIG, blood pressure, HdL and glucose respectively, were put forward. Odds ratios revealed that increased blood pressure best predicted ROC WC in both males (OR 9.59; 95% CI 3.14–29.32) and females (OR 3.11; 95% CI 1.30–7.42) irrespective of age. We suggest that the optimal cut off point for the males be set at 90 cm, as opposed to the current 94 cm; whilst the female cut off be set at 98 cm as opposed to the existing cut off of 80 cm. Larger sample groups are recommended to justify our data.

Cardiometabolic health in adolescence and its association with educational outcomes

2019 ◽  
Vol 73 (12) ◽  
pp. 1071-1077 ◽  
Author(s):  
Paulina Correa-Burrows ◽  
Estela Blanco ◽  
Sheila Gahagan ◽  
Raquel Burrows
Keyword(s):  
Risk Factors ◽  
Blood Pressure ◽  
Educational Outcomes ◽  
Cardiometabolic Risk ◽  
International Diabetes Federation ◽  
Density Lipoprotein ◽  
Cardiometabolic Risk Factors ◽  
Cardiometabolic Health ◽  
Model Assessment ◽  
Grade Point

AimTo explore the association of selected cardiometabolic biomarkers and metabolic syndrome (MetS) with educational outcomes in adolescents from Chile.MethodsOf 678 participants, 632 (52% males) met criteria for the study. At 16 years, waist circumference (WC), systolic blood pressure, triglycerides (TG), high-density lipoprotein and glucose were measured. A continuous cardiometabolic risk score (zMetS) using indicators of obesity, lipids, glucose and blood pressure was computed, with lower values denoting a healthier cardiometabolic profile. MetS was diagnosed with the International Diabetes Federation/American Heart Association/National Heart, Lung, and Blood Institute joint criteria. Data on high school (HS) graduation, grade point average (GPA), college examination rates and college test scores were collected. Data were analysed controlling for sociodemographic, lifestyle and educational confounders.ResultzMetS, WC, TG and homeostatic model assessment of insulin resistance at 16 years were negatively and significantly associated with the odds of completing HS and taking college exams. Notably, for a one-unit increase in zMetS, we found 52% (OR: 0.48, 95% CI 0.227 to 0.98) and 39% (OR: 0.61, 95% CI 0.28 to 0.93) reduction in the odds of HS completion and taking college exams, respectively. The odds of HS completion and taking college exams in participants with MetS were 37% (95% CI 0.14 to 0.98) and 33% (95% CI 0.15 to 0.79) that of participants with no cardiometabolic risk factors. Compared with adolescents with no risk factors, those with MetS had lower GPA (515 vs 461 points; p=0.002; Cohen’s d=0.55). Adolescents having the MetS had significantly lower odds of passing the mathematics exam for college compared with peers with no cardiometabolic risk factors (OR: 0.49; 95% CI 0.16 to 0.95).ConclusionIn Chilean adolescents, cardiometabolic health was associated with educational outcomes.

Combined associations between moderate to vigorous physical activity and sedentary behaviour with cardiometabolic risk factors in children

2013 ◽  
Vol 38 (5) ◽  
pp. 477-483 ◽  
Author(s):  
Jean-Philippe Chaput ◽  
Travis John Saunders ◽  
Marie-Ève Mathieu ◽  
Mélanie Henderson ◽  
Mark Stephen Tremblay ◽  
...  
Keyword(s):  
Risk Factors ◽  
Blood Pressure ◽  
Waist Circumference ◽  
Diastolic Blood Pressure ◽  
Sedentary Behaviour ◽  
Screen Time ◽  
Cardiometabolic Risk ◽  
Sedentary Time ◽  
Density Lipoprotein ◽  
Hdl Cholesterol

The objective of this study was to examine the combined associations between time spent in moderate- to vigorous-intensity physical activity (MVPA) and time spent sedentary in relation to cardiometabolic risk factors in a cohort of Canadian children. A cross-sectional study was conducted on 536 white children aged 8–10 years with at least 1 obese biological parent. Time spent in MVPA and sedentary behaviour over 7 days was measured using accelerometry and participants were stratified by tertiles. Daily screen time over 7 days was also self-reported by the child. Outcomes included waist circumference, systolic and diastolic blood pressure, fasting triglycerides, high-density lipoprotein cholesterol, and glucose concentrations. Analyses of covariance comparing tertiles of sedentary time/MVPA showed that higher levels of MVPA were associated with lower waist circumference, fasting triglycerides and diastolic blood pressure, and higher high-density lipoprotein (HDL) cholesterol, irrespective of sedentary time. In linear regression, MVPA was inversely associated with waist circumference and diastolic blood pressure and positively associated with HDL cholesterol, independent of covariates including sedentary time. In contrast, sedentary time was positively associated with diastolic blood pressure but after adjustment for MVPA the association was no longer statistically significant. Self-reported screen time was positively associated with waist circumference and negatively associated with HDL cholesterol independent of covariates including MVPA. Overall, a high level of MVPA was associated with reduced cardiometabolic risk in this sample of children, regardless of their amount of sedentary behaviour. The type of sedentary behaviour (i.e., screen time) might be more important than overall sedentary time in relation to cardiometabolic risk.

scholarly journals Comparison of metabolic syndrome criteria in obese and overweight children

2010 ◽  
Vol 50 (5) ◽  
pp. 295 ◽  
Author(s):  
Astrid Anastasia Malonda ◽  
Helena Anneke Tangkilisan
Keyword(s):  
Blood Pressure ◽  
Metabolic Syndrome ◽  
Waist Circumference ◽  
Density Lipoprotein ◽  
Cross Sectional Study ◽  
Overweight Child ◽  
Test Results ◽  
Overweight Children ◽  
Obese Children ◽  
Cross Sectional

Background Metabolic syndrome (MS) is a group of disorders which occur in relation to increasing body weight. Only a few studies have reported the differences in the fulfillment of MS criteria between obese and overweight children, and none were from Indonesia.Objective To detennine the differences in metabolic syndrome disorders between obese and overweight children.Methods A cross-sectional study was conducted in Manado from May to August 2010. The diagnosis of MS is established by fulfilling three of five criteria: waist circumference  ≥90th percentile, blood pressure ≥ 90th  percentile, fasting blood sugar (FBS) ≥ 100 mg/dL, triglycerides  ≥110 mg/dL and high density lipoprotein (HDL) ≤40 mg/dL. Obesity was defined as body mass index (BMI) of> 3 SD and overweight as BMI of 2-3 SD. Results Results ere analyzed by x2 and t-test. Results Thirty obese and 30 overweight children aged 10-14years were examined for the disorders of MS. Twenty􀁄three obese and 4 overweight children had waist circumferences  ≥90th percentile. Seventeen obese and 3 overweight children had blood pressure  ≥90th percentile. No significant differences in FBS, HDL, and triglycerides were observed between the two groups. Thirteen obese children met the MS inclusion criteria, while only 1 overweight child did so (P<0.001).Conclusions High blood pressure (≥90th percentile) and waist circumference (≥90th  percentile) occurred were observed at higher frequency in obese children than in overweight children. The occurrence of MS in obese children was significantly higher than in overweight children.

scholarly journals Cardiometabolic Risk and Biomarker Trajectories Among Older Adults: Findings From the Health and Retirement Study

2020 ◽  
Vol 4 (Supplement_1) ◽  
pp. 429-429
Author(s):  
Qiao Wu ◽  
Eileen Crimmins ◽  
Jennifer Ailshire ◽  
Jung Ki Kim ◽  
Erfei Zhao
Keyword(s):  
Waist Circumference ◽  
Total Cholesterol ◽  
Pulse Pressure ◽  
Cardiometabolic Risk ◽  
Glycosylated Hemoglobin ◽  
Density Lipoprotein ◽  
Population Level ◽  
Health And Retirement Study ◽  
Cross Sectional ◽  
Retirement Study

Abstract The deterioration of the cardiovascular system is a process associated with aging. Most of the prior works have examined changes in cardiometabolic risk (CMR) while aging at the population level using cross-sectional data, but we study within-person changes for total CMR and separate risk factors, including pulse pressure, resting heart rate, C-reactive protein, glycosylated hemoglobin (HbA1c), high-density lipoprotein cholesterol, total cholesterol, waist circumference, and obesity. We examine 8-year changes (from 2006 to 2014) among respondents from the Health and Retirement Study biomarker sample (n=19,776). We use growth curve models to identify differences at baseline and the changes while aging, by age, gender, race/ethnicity, and education. Blacks, the old-old, the less educated, and current smokers have higher baseline CMR. The total CMR increases while people age over 8 years. HbA1c, waist circumference, and pulse pressure increase significantly with age. A reduction in total cholesterol can be observed and is likely due to medication. The CMR increase is no longer significant after accounting for socioeconomic status. The next step of this study is to focus on the disparity of risk distribution, in order to identify the individuals that are most in need of specific care and support.

scholarly journals Cardiovascular Risk Factors and Atherogenic Indices in an Iranian Population: Birjand East of Iran

2018 ◽  
Vol 12 ◽  
pp. 117954681875928 ◽  
Author(s):  
Toba Kazemi ◽  
Morteza Hajihosseini ◽  
Maryam Moossavi ◽  
Mina Hemmati ◽  
Masood Ziaee
Keyword(s):  
Blood Pressure ◽  
Risk Index ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Screening Tools ◽  
Lipoprotein Cholesterol ◽  
Atherogenic Index ◽  
Atherogenic Indices ◽  
High Prevalence ◽  
East Of Iran

Introduction: The alteration in serum lipid profile; increase in total cholesterol (TC), triacylglycerol (TAG), and low-density lipoprotein cholesterol (LDL-C); and reduction in high-density lipoprotein cholesterol (HDL-C) are key factors in cardiovascular disease progression. The high prevalence and severity of cardiovascular diseases require new screening tools for better evaluation. Atherogenic index (AI) (LDL-C/HDL-C) and coronary risk index (CRI) (TC/HDL-C) can be strong markers for predicting the risk of atherosclerosis and coronary heart disease and disclose the presence of LDL or TAG in the serum of related patients. To implement this strategy, the AIs and CRIs in our population were assessed. In this study, a total of 5207 subjects were recruited and AIs and CRIs were calculated for all of them. According to our data, age, body mass index, sex, as well as CRI and AI had affirmative correlation with TC, LDL-C, TAG, systolic blood pressure, and diastolic blood pressure. By increasing these factors, AIs and CRIs were augmented. Moreover, in situations where all atherogenic parameters are normal, these parameters may be the alternative screening tool.

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