scholarly journals Effects of Gelidium elegans on Weight and Fat Mass Reduction and Obesity Biomarkers in Overweight or Obese Adults: A Randomized Double-Blinded Study

Nutrients ◽  
2019 ◽  
Vol 11 (7) ◽  
pp. 1513 ◽  
Author(s):  
Choon Ok Kim ◽  
Youn Nam Kim ◽  
Duk-Chul Lee
Keyword(s):  
Body Weight ◽  
Fat Mass ◽  
Calorie Intake ◽  
Anthropometric Parameters ◽  
Edible Seaweed ◽  
Reduced Body ◽  
Significant Difference ◽  
Gelidium Elegans ◽  
Laboratory Biomarkers ◽  
Double Blinded

The edible seaweed Gelidium elegans (GEE) is known to inhibit adipocyte differentiation. However, there has been no report on its effects in humans. In this study, we investigated whether GEE reduces body weight or fat mass in obese or overweight individuals. A total of 78 participants were randomly assigned to the test (GEE extract 1000 mg/day) and placebo groups at a 1:1 ratio, and treated for 12 weeks. At six or 12 weeks after randomization, they were evaluated for anthropometric parameters, biomarkers, and body composition. Changes in body weight and fat mass between the two groups was significantly different, as determined using ANCOVA adjusted for baseline, calorie intake, and physical activity. Body weight and fat mass were significantly decreased by GEE after 12 weeks but increased in the placebo group. Moreover, although not significant, triglyceride levels tended to decrease after GEE intake. There was no significant difference in other laboratory biomarkers between the two groups. Taken together, these results suggested that GEE significantly reduced body weight, especially fat mass, in overweight or obese individuals.

scholarly journals Spine’s Sagittal Plane Curves’ Coherence with Anthropometric Parameters in Schoolchildren

2018 ◽  
Vol 3 (57) ◽  
Author(s):  
Vilma Mauricienė ◽  
Kristina Bačiulienė
Keyword(s):  
Body Weight ◽  
Body Mass ◽  
Fat Mass ◽  
Lumbar Lordosis ◽  
Thoracic Kyphosis ◽  
Anthropometric Measurements ◽  
Sagittal Profile ◽  
Anthropometric Parameters ◽  
Significant Difference ◽  
Free Body

The aim of this study — to identify how anthropometric measurements are connected with spine sagittal curves inschoolchildren.Anthropometric and sagittal body posture measurements were performed for 405 schoolchildren, age range 10—13years. Such anthropometric measurements as body height, weight, fat mass and fat free mass were assessed. Degreesof thoracic kyphosis and lumbar lordosis as sagittal profile features were evaluated.According to the data analysis could be concluded, that coherence between anthropometric parameters and spine’ssagittal profile differs according to gender. The number of statistically significant connections between these twoparameters’ groups was greater in boys. Anthropometric measurements had greater coherence with thoracic kyphosisin comparison with lumbar lordosis. Body weight and fat mass were statistically significantly different according tokyphosis and lordosis values in boys, although fat-free body mass had no significant difference with sagittal curves’expression. Body weight, fat mass and fat-free body mass among girls were associated only with thoracic kyphosis.Keywords: thoracic kyphosis, lumbar lordosis, height, weight, fat mass.

Effect of vitamin K supplementation on anthropometric parameters and adipokine levels – a systematic review

2019 ◽  
Vol 88 (4) ◽  
pp. 244-255
Author(s):  
Małgorzata Jamka ◽  
Harald Walach ◽  
Magdalena Hołubiec ◽  
Maria Wasiewicz ◽  
Jarosław Walkowiak
Keyword(s):  
Systematic Review ◽  
Body Mass Index ◽  
Body Weight ◽  
Body Mass ◽  
Vitamin K ◽  
Fat Mass ◽  
Cochrane Library ◽  
Anthropometric Parameters ◽  
The Cochrane Library

Aim. The aim of this systematic review was to assess the effect of vitamin K supplementation on anthropometric parameters and adipokine levels in adults.Material and Methods. Four databases (PubMed, Web of Sciences, Scopus and the Cochrane Library) were searched to select studies in which the effect of vitamin K supplementation on body weight, body mass index (BMI), fat mass, leptin and adiponectin levels were assessed.Results. We identified nine studies that included a total of 542 subjects. Vitamin K supplementation did not influence body weight, BMI and percentage of fat mass. In addition, the effect of vitamin K supplementation on adipokines levels was equivocal. Conclusions. Vitamin K supplementation did not affect anthropometric parameters and adipokines levels. Nevertheless, further studies are needed to clarify the effect of vitamin K supplementation on these parameters in adults.

scholarly journals Energy homeostasis in apolipoprotein AIV and cholecystokinin-deficient mice

2017 ◽  
Vol 313 (5) ◽  
pp. R535-R548 ◽  
Author(s):  
Jonathan Weng ◽  
Danwen Lou ◽  
Stephen C. Benoit ◽  
Natalie Coschigano ◽  
Stephen C. Woods ◽  
...  
Keyword(s):  
Body Weight ◽  
Energy Expenditure ◽  
Fat Mass ◽  
High Fat Diet ◽  
Energy Homeostasis ◽  
Lipid Transport ◽  
Fat Absorption ◽  
High Fat ◽  
Reduced Body ◽  
Brown Adipose

Apolipoprotein AIV (ApoAIV) and cholecystokinin (CCK) are well-known satiating signals that are stimulated by fat consumption. Peripheral ApoAIV and CCK interact to prolong satiating signals. In the present study, we hypothesized that ApoAIV and CCK control energy homeostasis in response to high-fat diet feeding. To test this hypothesis, energy homeostasis in ApoAIV and CCK double knockout (ApoAIV/CCK-KO), ApoAIV knockout (ApoAIV-KO), and CCK knockout (CCK-KO) mice were monitored. When animals were maintained on a low-fat diet, ApoAIV/CCK-KO, ApoAIV-KO, and CCK-KO mice had comparable energy intake and expenditure, body weight, fat mass, fat absorption, and plasma parameters relative to the controls. In contrast, these KO mice exhibited impaired lipid transport to epididymal fat pads in response to intraduodenal infusion of dietary lipids. Furthermore, ApoAIV-KO mice had upregulated levels of CCK receptor 2 (CCK2R) in the small intestine while ApoAIV/CCK-KO mice had upregulated levels of CCK2R in the brown adipose tissue. After 20 wk of a high-fat diet, ApoAIV-KO and CCK-KO mice had comparable body weight and fat mass, as well as lower energy expenditure at some time points. However, ApoAIV/CCK-KO mice exhibited reduced body weight and adiposity relative to wild-type mice, despite having normal food intake. Furthermore, ApoAIV/CCK-KO mice displayed normal fat absorption and locomotor activity, as well as enhanced energy expenditure. These observations suggest that mice lacking ApoAIV and CCK have reduced body weight and adiposity, possibly due to impaired lipid transport and elevated energy expenditure.

scholarly journals Comparison of morphine and fentanyl in attenuation of Intra operative stress response under general anesthesia: A randomized double blinded study

2014 ◽  
Vol 5 (4) ◽  
pp. 65-68
Author(s):  
R Krishna Prabu ◽  
P Rani ◽  
NP Madhu
Keyword(s):  
Body Weight ◽  
Stress Response ◽  
General Anesthesia ◽  
Elective Surgery ◽  
Serum Cortisol ◽  
Blood Samples ◽  
Significant Difference ◽  
Blinded Study ◽  
Cortisol Levels ◽  
Double Blinded

Background: This randomized double blinded study was done to compare the effect of intravenous morphine and fentanyl in attenuation of stress response during surgeries under general anesthesia in adults. The attenuation of stress response was analyzed with changes in serum cortisol and glucose levels one hour after induction of anesthesia. Methods: Fifty consented healthy volunteers in age group 20-50, under ASA I and ASA II posted for elective surgery were included in the study. Two groups of 25 each, group M who received 0.2 mg/kg body weight of morphine and group F who received 2 microgram/kg body weight of fentanyl before anaesthetic induction were compared. The members of two groups were randomly allocated and double blinded using sealed envelope technique. Blood samples were collected for baseline glucose and cortisol in all the subjects. One hour after the administration of study drugs, which was given at the time of induction blood samples were collected for analysis of glucose and cortisol. The changes in blood glucose and serum cortisol levels were compared at the end of the study using independent samples ‘t’ test. Results: There was no significant difference in blood sugar levels in both groups at the end of 1 hour. But there was significant increase in serum cortisol levels in group F compared to group M. Conclusion: This study concludes that morphine is better than fentanyl in attenuation of Intraoperative stress by effectively controlling serum cortisol levels. DOI: http://dx.doi.org/10.3126/ajms.v5i4.9796 Asian Journal of Medical Sciences 2014 Vol.5(4); 65-68

scholarly journals Efficacy of the WATERinMOTION Aquatics Exercise Programme on the Body Weight and Composition of Sedentary Older Women with Overweight/Obesity

2021 ◽  
Vol 10 (2) ◽  
pp. 19-24
Author(s):  
Mohammadreza Rezaeipour ◽  
◽  
Gennady Leonidovich Apanasenko ◽  
Zahra Raghi ◽  
◽  
...  
Keyword(s):  
Body Weight ◽  
Older Women ◽  
Fat Mass ◽  
Exercise Program ◽  
Exercise Programme ◽  
Nutritional Intervention ◽  
The Body ◽  
Control Group ◽  
Convenience Sample ◽  
Significant Difference

Some controversy remains regarding the effects of aquatic exercise on body weight and composition. The purpose of this study was to determine the short-term impacts of the WATERinMOTION aquatics exercise program on body weight and composition without nutritional intervention in sedentary older women with overweight/ obesity. The study was developed as a quasi-experimental project (pre/post-study). Forty-four inactive women were volunteers from a convenience sample with a mean age of 71.1±5.7 years (Ukraine, 2019). Participants were allocated randomly into two groups: WATERinMOTION (n=22) or a control group (n=22). Meanwhile, the WATERinMOTION group performed the WATERinMOTION exercise programme with two weekly sessions of 55 minutes each. The control subjects did not participate in any physical exercises. They were asked to perform their routine activities during the study. Both programmes lasted one month. Height, body weight, body mass index (BMI), waist circumference (WC), fat mass (FM), total body water (TBW), and free fat mass (FFM) were the anthropometric variables that were measured pre/post-study. The analysis found statistically significant differences in body weight (-0.7, P=0.004), BMI (-0.3, P=0.002), and FM (-0.6, P=0.03) between the pre and post measurements of the WATERinMOTION group. Moreover, the comparison of groups at post revealed a significant difference in body weight (P˂0.001), BMI (P˂0.001), TBW (P=0.005), FM (P˂0. 001), FFM (P=0.003), and WC (P=0.007). The WATERin- MOTION programme, which is not associated with nutritional monitoring, showed significant benefits for losing weight and the body composition of sedentary older women who are overweight and/or obese.

scholarly journals The effect of calorie restricted diet on anthropometric and biochemical parameters in Sprague Dawley rats

2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Muhammad Fakhruddin Irfan Sazali ◽  
Maleeka Abdullah Hilmy ◽  
Norshafarina Shari ◽  
Lilik Herawati ◽  
Nurul Izza Nordin ◽  
...  
Keyword(s):  
Biochemical Parameters ◽  
Healthy Aging ◽  
Calorie Intake ◽  
Sprague Dawley ◽  
Restricted Diet ◽  
Anthropometric Parameters ◽  
Content Type ◽  
Low Calorie ◽  
Sd Rats ◽  
Significant Difference

Purpose Calorie restricted diets are known to improve health and promote healthy aging. This happens because of controlled inflammation and metabolism in the body. This study aims to evaluate the differences in anthropometric and biochemical parameters in Sprague Dawley (SD) rats because of consumption of a calorie restricted diet. Design/methodology/approach The study divided SD rats (n = 15) into 3 groups consuming high calorie intake (HCI), medium calorie intake and low calorie intake (LCI). Anthropometric parameters were determined through measurement of abdominal circumference (AC), thoracic circumference (TC), body length and body weight (BW). Biochemical parameters analyzed in this study were fasting blood glucose level and full blood lipid profile. Nutritional status was obtained based on food consumption, energy intake (EI) and food efficiency rate. Measurements were taken for a period of four weeks. Findings Analysis on anthropometric parameters indicates a significant difference in mean BW between HCI (230.44 ± 1.47 g) and LCI (188.54 ± 1.50 g). There is a significant difference in abdominal TC ratio (p < 0.001; F = 13.599) in the LCI group (1.01 ± 0.00714) compared to the HCI group (1.04 ± 0.00858). Post hoc for nutrition parameters indicates a significant difference in mean EI between HCI (9.71 ± 0.006 kJ) and LCI (3.21 ± 0.001 kJ). There is a significant effect (p < 0.0001; F = 3042872.02) of EI on rats in all three groups. HDL levels were significantly higher (p < 0.0001; F = 1536.89) in the LCI group (68.60 ± 0.55 mg/dL) compared to the HCI group (49.40 ± 0.55 mg/dL). The Pearson’s correlation results show a strong positive correlation in EI with BW (p < 0.01; r = 0.988), AC (p < 0.01; r = 0.970) and body mass index (p < 0.01; r = 0.972). Originality/value Low calorie diet has been proven to affect anthropometric development and has shown improvements in biochemical parameters of the rats. This may result in healthy aging which could prevent later-life diseases.

Twelve weeks low glycemic load diet reduced body weight, fat mass and hunger in overweight/obese children

2008 ◽  
Vol 37 (4) ◽  
pp. 497-504 ◽  
Author(s):  
Zs. Fajcsák ◽  
V. Kovács ◽  
A. Gábor ◽  
T. Szamosi ◽  
É. Martos
Keyword(s):  
Body Weight ◽  
Fat Mass ◽  
Glycemic Load ◽  
Obese Children ◽  
Reduced Body

scholarly journals Body measurements and serum lipid profile of overweight adult dogs fed diet with containing conjugated linoleic acid

2011 ◽  
Vol 41 (11) ◽  
pp. 2020-2025 ◽  
Author(s):  
Nancy Lorena Montaño Rivera ◽  
Ananda Portela Félix ◽  
Fabiano Montiani Ferreira ◽  
Ana Vitória Fisher da Silva ◽  
Alex Maiorka
Keyword(s):  
Body Weight ◽  
Linoleic Acid ◽  
Total Cholesterol ◽  
Conjugated Linoleic Acid ◽  
Body Fat ◽  
Fat Mass ◽  
Subcutaneous Tissue ◽  
Body Fat Mass ◽  
Tissue Thickness ◽  
Significant Difference

Studies with human beings and animals have shown that dietary conjugated linoleic acid (CLA) promotes changes in body structure, markedly, body fat reduction. This research aimed to assess the effect of CLA (60% of conjugated linoleic acid methyl ester, at the proportion of 1:1 of the 9, 11: 10, 12 isomers) on changes in body weight, subcutaneous tissue thickness, body fat mass and concentration of serum lipids (triacylglycerols, total cholesterol, LDL and HDL) in overweight dogs. Dogs of different breeds weighting 16.85±7.13 assigned in a randomized assay. Two types of diets were offered for 120 days: control (-CLA) and test (+CLA, 0.3%). There was no difference between control and test groups considering body weight and serum levels of triacylglycerols, total cholesterol and LDL portion. There was a significant difference between the final and initial results for subcutaneous tissue thickness and body fat mass and for serum concentration of HDL in dogs supplemented with CLA. The addition of 0.3% of CLA in the diet of overweight dogs decreased the fat deposition on subcutaneous tissue and the development of body fat mass but increased blood levels of HDL.

scholarly journals Global Igfbp1 deletion does not affect prostate cancer development in a c-Myc transgenic mouse model

2011 ◽  
Vol 211 (3) ◽  
pp. 297-304 ◽  
Author(s):  
Ashley Gray ◽  
William J Aronson ◽  
R James Barnard ◽  
Hemal Mehta ◽  
Junxiang Wan ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Body Weight ◽  
Mouse Model ◽  
Transgenic Mouse ◽  
Fat Mass ◽  
Transgenic Mouse Model ◽  
Metabolic Effects ◽  
Nuclear Antigen ◽  
Ki 67 ◽  
Significant Difference

Circulating insulin-like growth factor binding protein 1 (IGFBP1) levels vary in response to nutritional status, and pre-clinical studies suggest that elevated IGFBP1 may be protective against the development and progression of prostate cancer. We hypothesized that global deletion of Igfbp1 would accelerate the development of prostate cancer in a c-Myc transgenic mouse model. To test our hypothesis, c-Myc transgenic mice (Myc/BP-1 wild-type (WT)) were crossed and interbred with the Igfbp1 knockout mice (Myc/BP-1 KO). The animals were placed on a high-protein diet at weaning, weighed every 2 weeks, and euthanized at 16 weeks of age. Prostate histopathology was assessed and proliferation status was determined by Ki-67 and proliferating cell nuclear antigen analyses. IGF-related serum biomarkers and body composition were measured. No significant difference in the incidence of prostate cancer was observed between the Myc/BP-1 KO and the Myc/BP-1 WT mice (65 and 80% respectively, P=0.48). Proliferation was significantly decreased by 71% in prostate tissue of Myc/BP-1 KO mice compared with Myc/BP-1 WT mice. Myc/BP-1 KO mice exhibited a significant 6.7% increase in body weight relative to the Myc/BP-1 WT mice that was attributed to an increase in fat mass. Fasting insulin levels were higher in the Myc/BP-1 KO mice without any difference between the groups in fasting glucose concentrations. Thus, contrary to our hypothesis, global deletion of Igfbp1 in a c-Myc transgenic mouse model did not accelerate the development of prostate cancer. Global Igfbp1 deletion did result in a significant increase in body weight and body fat mass. Further studies are required to understand the underlying mechanisms for these metabolic effects.

scholarly journals Commensal Hafnia alvei strain reduces food intake and fat mass in obese mice—a new potential probiotic for appetite and body weight management

2020 ◽  
Vol 44 (5) ◽  
pp. 1041-1051 ◽  
Author(s):  
Romain Legrand ◽  
Nicolas Lucas ◽  
Manon Dominique ◽  
Saida Azhar ◽  
Camille Deroissart ◽  
...  
Keyword(s):  
Body Weight ◽  
Weight Gain ◽  
Food Intake ◽  
Weight Management ◽  
Fat Mass ◽  
Body Weight Gain ◽  
Overweight And Obesity ◽  
Obese Mice ◽  
Hafnia Alvei ◽  
Reduced Body

Abstract Background/objectives Based on the recent identification of E.coli heat shock protein ClpB as a mimetic of the anorexigenic α-melanocyte stimulating hormone (α-MSH), the objective of this study was to preclinically validate Hafnia alvei, a ClpB-producing commensal bacterium as a potential probiotic for appetite and body weight management in overweight and obesity. Methods The involvement of enterobacterial ClpB in the putative anti-obesity effects was studied using ClpB-deficient E.coli. A food-grade H. alvei HA4597 strain synthetizing the ClpB protein with an α-MSH-like motif was selected as a candidate probiotic to be tested in ob/ob and high-fat diet (HFD)-fed obese and overweight mice. The relevance of the enterobacterial ClpB gene to human obesity was studied by in silico analysis of fecal metagenomes of 569 healthy individuals from the “MetaHIT” database. Results Chronic per os administration of native but not ClpB-deficient E.coli strain reduced body weight gain (p < 0.05) and daily meal frequency (p < 0.001) in ob/ob mice. Oral gavage of H.alvei for 18 and 46 days in ob/ob and HFD-fed obese mice, respectively, was well tolerated, reduced body weight gain and fat mass in both obesity models (p < 0.05) and decreased food intake in hyperphagic ob/ob mice (p < 0.001). Elevated fat tissue levels of phosphorylated hormone-sensitive lipase were detected in H.alvei -treated ob/ob mice (p < 0.01). Enterobacterial ClpB gene richness was lower in obese vs. non-obese humans (p < 0.0001) and correlated negatively with BMI in genera of Enterobacter, Klebsiella and Hafnia. Conclusions H.alvei HA4597 strain reduces food intake, body weight and fat mass gain in hyperphagic and obese mice. These data combined with low enterobacterial ClpB gene abundance in the microbiota of obese humans provide the rationale for using H.alvei as a probiotic for appetite and body weight management in overweight and obesity.

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