scholarly journals In Search of Panacea—Review of Recent Studies Concerning Nature-Derived Anticancer Agents

Nutrients ◽  
2019 ◽  
Vol 11 (6) ◽  
pp. 1426 ◽  
Author(s):  
Dawid Przystupski ◽  
Magdalena J. Niemczura ◽  
Agata Górska ◽  
Stanisław Supplitt ◽  
Krzysztof Kotowski ◽  
...  
Keyword(s):  
Public Health ◽  
Anticancer Agents ◽  
Antitumor Agents ◽  
Public Health Problem ◽  
Major Public Health Problem ◽  
Natural Substances ◽  
Cycle Growth ◽  
The World ◽  
Epigenetic Modulation ◽  
Causes Of Deaths

Cancers are one of the leading causes of deaths affecting millions of people around the world, therefore they are currently a major public health problem. The treatment of cancer is based on surgical resection, radiotherapy, chemotherapy or immunotherapy, much of which is often insufficient and cause serious, burdensome and undesirable side effects. For many years, assorted secondary metabolites derived from plants have been used as antitumor agents. Recently, researchers have discovered a large number of new natural substances which can effectively interfere with cancer cells’ metabolism. The most famous groups of these compounds are topoisomerase and mitotic inhibitors. The aim of the latest research is to characterize natural compounds found in many common foods, especially by means of their abilities to regulate cell cycle, growth and differentiation, as well as epigenetic modulation. In this paper, we focus on a review of recent discoveries regarding nature-derived anticancer agents.

scholarly journals Cerebral Cystic Echinococcosis

2020 ◽  
Vol 2020 ◽  
pp. 1-5
Author(s):  
Abolghasem Siyadatpanah ◽  
Enrico Brunetti ◽  
Amir Emami Zeydi ◽  
Yousef Dadi Moghadam ◽  
Nelson Iván Agudelo Higuita
Keyword(s):  
Public Health ◽  
Health Problem ◽  
Larval Stage ◽  
Cystic Echinococcosis ◽  
Public Health Problem ◽  
Major Public Health Problem ◽  
Cestode Species ◽  
Iranian Patient ◽  
The World ◽  
The Brain

Cystic echinococcosis (CE) is a neglected helminthic disease and major public health problem in several regions of the world. The zoonosis is caused by the larval stage of different cestode species belonging to the genus Echinococcus. CE can affect any organ with the liver and lungs being most commonly involved. The brain is involved in less than 2% of the cases. We report a case of a CE1 echinococcal cyst of the brain in an Iranian patient.

scholarly journals Targeted Nutrition in Chronic Disease

Nutrients ◽  
2020 ◽  
Vol 12 (6) ◽  
pp. 1682
Author(s):  
Peter Bergman ◽  
Susanna Brighenti
Keyword(s):  
Public Health ◽  
Chronic Disease ◽  
Health Problem ◽  
Public Health Problem ◽  
Aging Population ◽  
Major Public Health Problem ◽  
The World

Today, chronic disease is a major public health problem around the world that is rapidly increasing with a growing and aging population [...]

scholarly journals Serious non-fatal unintentional injuries among in-school adolescents in Sri Lanka: results from the 2016 Sri Lankan Global School-Based Health Survey

2020 ◽  
Author(s):  
Sashimali Wickramasinghe ◽  
Nalika Gunawardena ◽  
Dhanusha Punyadasa ◽  
Shanthi Gunawardena ◽  
Champika Wickramasinghe ◽  
...  
Keyword(s):  
Public Health ◽  
Sri Lanka ◽  
Health Survey ◽  
Health Problem ◽  
Public Health Problem ◽  
Major Public Health Problem ◽  
Age Group ◽  
Unintentional Injuries ◽  
School Based ◽  
The World

Abstract Background Unintentional injuries among adolescents is a major public health problem the world over. A great majority of the annual deaths among adolescents is due to unintentional injuries; it is also the leading cause of death among adolescents in the world. The aim of this study was to estimate the incidence of injuries and their associated factors among school going adolescents aged 13-17 years using data from the most recent Global School-Based Health Survey (GSHS) conducted in Sri Lanka. Methods A cross-sectional survey was conducted using a self-administered questionnaire, among 3,262 adolescents attending government schools. The sample was selected through a two-staged cluster sampling technique. In the first stage, 40 schools were selected using probabilities proportional to school enrollment size, from all schools in the country that have classes in grades 8-12 . Then, from the selected schools, classes were selected using systematic equal probability sampling with a random start. The weighted prevalence was calculated, and logistic regression analysis was conducted in order to determine the correlates. Results During the 12 months before the survey, 35.8% (95% CI-30.7 - 41.1) of the students reported being seriously injured one or more times. The injuries were more common among males, but were equally common among the two different age groups (13-15 age group vs 16-17 age group). The most common type of injury was cut or stab wounds (5.5%), followed by broken bones/dislocated joints (5.3%). Multivariable analysis revealed that only a few factors were associated with injury, such as being of the male sex, being bullied, being physically attacked, and/or being in a physical fight. Conclusion This study demonstrated that the prevalence of serious unintentional injuries among school going adolescents is a major public health problem in Sri Lanka. This timely and comprehensive survey would help policy makers and researchers identify the unmet needs related to adolescent injuries. Furthermore, evidence generated form the study should be given due consideration when designing school-based interventions to prevent adolescent injuries.

scholarly journals Antidiabetic Activity of 40 Plants of the Senegalese Flora, an Important Therapeutic Diversity for Populations

2020 ◽  
pp. 15-32
Author(s):  
Ousmane Faye ◽  
Cheikh Sall ◽  
Omar Kane
Keyword(s):  
Public Health ◽  
Insulin Action ◽  
Major Part ◽  
Public Health Problem ◽  
Modern Medicine ◽  
Public Health Care ◽  
Antidiabetic Activity ◽  
Major Public Health Problem ◽  
Health Care Coverage ◽  
The World

Diabetes mellitus is group of a metabolic desorder caused by hyperglycemia resulting from defects in insulin secretion, insulin action, or both. It is a major public health problem in all countries of the world. In Africa, it was predicted that the continent, will see the greatest increase, from 19 millions in 2019 to 47 million diabetics in 2045. In the absence of sufficient public health care coverage and the high cost of modern medicine, major part of the population of developing countries turns to traditional medicine. These medicine offer a new alternative for the management of diabetes from plant organs. Most of the used part of plants has not yet been scientifically approved by researchers. In this article, we have inventorised the medicinal plants of the Senegalese flora used in the management of diabetes and whose activity has been validated scientifically by researchers.

Glycated Albumin – More Than the Missing Link in the Evaluation of Diabetes Control

2014 ◽  
Vol 21 (2) ◽  
pp. 137-150 ◽  
Author(s):  
Ilie-Robert Dinu ◽  
Eugen Moţa
Keyword(s):  
Public Health ◽  
Diabetes Mellitus ◽  
Liver Diseases ◽  
Diabetes Complications ◽  
Glycated Albumin ◽  
Public Health Problem ◽  
Glycated Haemoglobin ◽  
Diabetes Control ◽  
Major Public Health Problem ◽  
The World

Abstract Diabetes mellitus represents a major public health problem in the world and glycemic control is very important in subjects with diabetes. Glycation of many proteins is increased in subjects with diabetes compared with persons without diabetes. Glycated albumin (GA) has emerged as a possible glycation index for intermediate-term diabetes control. There is evidence that GA can be considered a better parameter than glycated haemoglobin in many conditions including pregnancy, chronic kidney disease, liver diseases and anemia. Several reports indicate that GA plays a role in the pathogeny of diabetes complications, mainly in diabetic nephropathy and retinopathy. There are several limitations for using GA including the lack of standardization in the laboratories. Several studies are needed in order to understand the place of GA in the pathogeny of diabetes complications and the role in assessing the metabolic control

scholarly journals What’s new for the clinician – summaries of recently published papers (September 2021)

2021 ◽  
Vol 76 (08) ◽  
pp. 492-495
Author(s):  
Veerasamy Yengopal
Keyword(s):  
Public Health ◽  
Quality Of Life ◽  
Weight Loss ◽  
Early Childhood Caries ◽  
Primary Teeth ◽  
Public Health Problem ◽  
Major Public Health Problem ◽  
The World ◽  
Untreated Caries

It is estimated that 621 million children throughout the world have untreated caries on primary teeth. 1 Early childhood caries (ECC), which affects preschool children, progresses rapidly and is associated with pain, difficulty chewing, weight loss, difficulty sleeping, altered behaviour, and a poorer quality of life for affected children and theirfamilies. Children with dental caries have greater treatmentneed, which is expensive and not readily accessible in most developing countries. In South Africa, ECC is a major public health problem with caries rates among children as high as 70% in some provinces.

scholarly journals Mongolian spot

2014 ◽  
Vol 1 (1) ◽  
pp. 6
Author(s):  
Roshan Bista ◽  
Prativa Pandey
Keyword(s):  
Public Health ◽  
Differential Diagnosis ◽  
Child Abuse ◽  
Pediatric Patient ◽  
Health Problem ◽  
Public Health Problem ◽  
Major Public Health Problem ◽  
The World ◽  
Lumbar Area ◽  
Mongolian Spot

Colorful skin spots on a pediatric patient can easily be mistaken as signs of child abuse.  Professionals should therefore gain knowledge about Mongolian spots; also known as Mongolian blue spots. These are flat, congenital and benign birthmarks, commonly located in sacro-coccygeal or lumbar area of an infant. Child abuse is a major public health problem across the world. The most common manifestations of physical child abuse are cutaneous, and their recognition and differential diagnosis are of great importance. Mongolian spots may appear as signs of child abuse; however, Mongolian spots are harmless.

How coffee affects metabolic syndrome and its components

2017 ◽  
Vol 8 (6) ◽  
pp. 2089-2101 ◽  
Author(s):  
B. Baspinar ◽  
G. Eskici ◽  
A. O. Ozcelik
Keyword(s):  
Public Health ◽  
Metabolic Syndrome ◽  
Health Problem ◽  
Public Health Problem ◽  
Major Public Health Problem ◽  
The World

Metabolic syndrome, with its increasing prevalence, is becoming a major public health problem throughout the world.

scholarly journals GLOBAL OBESITY AND PAKISTAN

2020 ◽  
Vol 18 (2) ◽  
pp. 43-44
Author(s):  
Iftikhar Ahmad
Keyword(s):  
Public Health ◽  
Developing Countries ◽  
Health Problem ◽  
Public Health Problem ◽  
Communicable Diseases ◽  
Major Public Health Problem ◽  
Double Burden ◽  
Non Communicable Diseases ◽  
The World ◽  
Developed World

Obesity is rapidly becoming a major public health problem in many parts of the world, including Pakistan. Developed world is viewing a huge switchover from acute and communicable diseases to the chronic and non-communicable diseases. However many developing countries including Pakistan, experience the double burden of communicable and non-communicable diseases.

scholarly journals Characteristics of the New Coronavirus Named SARS-CoV-2 Responsible for an Infection Called Coronavirus Disease 2019 (COVID-19)

2020 ◽  
pp. 68-77
Author(s):  
Modou Mamoune Mbaye ◽  
Bouchra El Khalfi ◽  
Said El Hafiane ◽  
Abdelaziz Soukri
Keyword(s):  
Public Health ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
Public Health Problem ◽  
Economic Consequences ◽  
Major Public Health Problem ◽  
Shortness Of Breath ◽  
Chest Tightness ◽  
The World ◽  
Speed Of Propagation

The new coronavirus called Covid-19, previously known as 2019-nCOV that has been reported in China, is rapidly spreading around the world at breakneck speed. Covid-19, a virus that was unknown to us before the outbreak in Wuhan (China) in December 2019, remains a major public health problem today. However, a new coronavirus named SARS-CoV-2 has been identified as responsible for this disease. Human-to-human transmission is no longer a matter of debate. In general, 2019-nCOV is an infectious, acute resolved disease, but it can also be very fatal especially with certain comorbidities such as hypertension, diabetes, coronary heart disease, cerebral infarction or even chronic bronchitis. The main symptoms of Covid-19 are fever, cough, shortness of breath, chest tightness / pain, respectively. Until now, the source of the virus and the pathogenesis of this disease remain unknown. Considering the speed of propagation, the mortality rate in the world and its economic consequences, it is urgent to find drugs for the treatment even a vaccine in order to cut short the Covid-19. In this article, we will try to detail all the information relating to this virus.

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