scholarly journals Increased Intestinal Absorption of Vitamin U in Steamed Graviola Leaf Extract Activates Nicotine Detoxification

Nutrients ◽  
2019 ◽  
Vol 11 (6) ◽  
pp. 1334
Author(s):  
Eun-Hye Choi ◽  
Seon-Bong Lee ◽  
Da-Yeon Lee ◽  
Goon-Tae Kim ◽  
Soon-Mi Shim ◽  
...  
Keyword(s):  
Intestinal Absorption ◽  
Cellular Uptake ◽  
Hepg2 Cells ◽  
Leaf Extract ◽  
Sensory Quality ◽  
Bioactive Components ◽  
Treatment Control ◽  
Food Ingredients ◽  
Natural Therapy ◽  
Vitamin U

Graviola leaves contain much vitamin U (vit U), but their sensory quality is not good enough for them to be developed as food ingredients. Addition of excipient natural ingredients formulated alongside vit U as active ingredients could enhance not only its sensory quality but also its bioavailability. The objectives of this study were to measure the bioaccessibility and intestinal cellular uptake of bioactive components, including rutin, kaempferol-rutinoside, and vit U, from steamed extract of graviola leaves (SGV) and SGV enriched with kale extract (SGK), and to examine how much they can detoxify nicotine in HepG2 cells. The bioaccessibility of vit U from SGV and SGK was 82.40% and 68.03%, respectively. The cellular uptake of vit U in SGK by Caco-2 cells was higher than that in SGV. Cotinine content converted from nicotine in HepG2 cells for 120 min was 0.22 and 0.25 μg/mg protein in 50 μg/mL of SGV and SGK, respectively, which were 2.86 and 3.57 times higher than the no-treatment control. SGK treatment of HepG2 cells upregulated CYP2A6 three times as much as did that of SGV. Our results suggest that graviola leaf extract enriched with excipient ingredients such as kale could improve vit U absorption and provide a natural therapy for detoxifying nicotine.

scholarly journals Antihyperlipidemic effect of a Rhamnus alaternus leaf extract in Triton-induced hyperlipidemic rats and human HepG2 cells

2018 ◽  
Vol 101 ◽  
pp. 501-509 ◽  
Author(s):  
Mustapha Tacherfiout ◽  
Petar D. Petrov ◽  
Marco Mattonai ◽  
Erika Ribechini ◽  
Joan Ribot ◽  
...  
Keyword(s):  
Hepg2 Cells ◽  
Leaf Extract ◽  
Rhamnus Alaternus

Phytochemical Screening and Larvicidal Assessment of Bellyache Bush (Jatropha gossypiifolia) Leaf Extracts Against Culex quinquefasciatus Larvae

2021 ◽  
Vol 42 (1) ◽  
pp. 19-24
Author(s):  
J.H. Buduwara ◽  
T. Adiel ◽  
R. Sami ◽  
M.L. Tafem
Keyword(s):  
Culex Quinquefasciatus ◽  
Leaf Extract ◽  
Larval Mortality ◽  
Fourth Stage ◽  
Bioactive Components ◽  
Leaf Extracts ◽  
Development Of Resistance ◽  
Third Stage ◽  
Ethanolic Leaf Extract ◽  
Jatropha Gossypiifolia

The development of resistance by Culex mosquitoes to synthetic insecticides has necessitated the continued search for alternative ones from plants. This study screened the preliminary qualitative phytochemicals and assessed the larvicidal efficacy of extracts of J. gossypiifolia leaf against third and fourth stage Culex quinquefasciatus larvae. The J. gossypiifolia was screened for the presence of phytochemicals using standard methods. After twenty-four (24) hours post exposure of both third and fourth stage C. quinquefasciatus larvae against different concentrations, (2.0mg/ml, 4.0mg/ml, 6.0mg/ml, 8.0mg/ml and 10 mg/ml) of various extracts. It showed that larval mortality increases significantly (p<0.05) with increase in extracts concentration. Acetone leaf extract showed highest mortality at 10mg/ml with 85% third stage Culex larvae mortality, followed by ethanolic leaf extract. However, least mortality was observed in n-Hexane leaf extract with 15% larval mortality against fourth stage Culex larvae. Low LC and LC values (3.715mg/ml and 12.490mg/ml) were noticed in 50 90 acetone leaf extract of J. gossypiifolia. The study observed that the highest LC and LC values (9.104mg/ml and 50 90 22.877mg/ml) were noticed in hexane leaf extracts. Conclusively, acetone leaf extract of J. gossypiifolia can be harnessed to control Culex larvae. However, there is a need to ascertain the quantities of bioactive components of J. gossypiifolia and its toxicity to non-target organisms. Keywords: Jatropha gossypiifolia, Phytochemicals, Culex larvae

Comparative pharmacokinetics of major bioactive components from Puerariae Radix-Gastrodiae Rhizome extracts and their intestinal absorption in rats

2019 ◽  
Vol 1105 ◽  
pp. 38-46 ◽  
Author(s):  
Chang-Shun Liu ◽  
Xiao Liang ◽  
Xiao-Han Wei ◽  
Fei-Long Chen ◽  
Qing-Fa Tang ◽  
...  
Keyword(s):  
Intestinal Absorption ◽  
Bioactive Components ◽  
Puerariae Radix

scholarly journals Modulatory Effects of Interspecific and Gourd Rootstocks on Crop Performance, Physicochemical Quality, Bioactive Components and Postharvest Performance of Diploid and Triploid Watermelon Scions

Agronomy ◽  
2020 ◽  
Vol 10 (9) ◽  
pp. 1396 ◽  
Author(s):  
Marios C. Kyriacou ◽  
Georgios A. Soteriou ◽  
Youssef Rouphael
Keyword(s):  
Fruit Quality ◽  
Sensory Quality ◽  
Reducing Sugars ◽  
Vegetable Crops ◽  
Bioactive Components ◽  
Biotic And Abiotic Stresses ◽  
Crop Performance ◽  
Lycopene Content ◽  
Triploid Watermelon ◽  
Stable Yield

Vegetable grafting has become entrenched as a sustainable tool for addressing biotic and abiotic stresses of vegetable crops, including watermelon. The concerted action of scion–rootstock genotypes in shaping crop performance, fruit quality and postharvest behavior of watermelon is critical. In this respect, scions of different ploidy grafted on interspecific and gourd rootstocks were assessed. Yield traits were strongly influenced by rootstock, as opposed to fruit morphometric characteristics. Interspecific rootstock supported stable yield across seasons with a 20.5% increase over gourd, and induced thicker rind and higher pulp firmness by 30.1% over gourd, which constitute advantageous traits for shelf-life. Interspecific rootstock also increased lycopene content, which was further influenced by scion genotype irrespective of ploidy. Triploid cultivars attained higher firmness but lower sugars than diploid, which renders the former particularly prone to loss of sensory quality during postharvest depletion of sugars. Although total and reducing sugars decreased during storage, sucrose increased, which in conjunction with the postharvest accumulation of lycopene sheds new light on the postharvest physiology of watermelon. The marginal rootstock effect on sugars renders interspecific rootstock superior to gourd on account of higher yield, firmness and lycopene content. The present work constitutes a contribution toward understanding rootstock–scion relations and how they mediate crop performance, fruit quality and postharvest behavior of watermelon.

Sensory quality definition of food ingredients

2010 ◽  
pp. 186-202 ◽  
Author(s):  
A. Van Biesen ◽  
C. Petit ◽  
E. Vanzeveren ◽  
N.V. Puratos
Keyword(s):  
Sensory Quality ◽  
Food Ingredients ◽  
Definition Of

Phytochemical Profile, and Antiproliferative and Proapoptotic Effects of Pouteria ramiflora (Mart.) Radlk. Leaf Extract, and Its Synergism with Cisplatin in HepG2 Cells

2020 ◽  
Author(s):  
Katiuska Tuttis ◽  
Daryne Lu Maldonado Gomes da Costa ◽  
Juliana Mara Serpeloni ◽  
Lourdes Campaner dos Santos ◽  
Eliana Aparecida Varanda ◽  
...  
Keyword(s):  
Hepg2 Cells ◽  
Leaf Extract ◽  
Phytochemical Profile

GC–MS analysis of bioactive components and synthesis of gold nanoparticle using Chloroxylon swietenia DC leaf extract and its larvicidal activity

2015 ◽  
Vol 148 ◽  
pp. 1-8 ◽  
Author(s):  
Govindasamy Balasubramani ◽  
Rajendiran Ramkumar ◽  
Narayanaswamy Krishnaveni ◽  
Rajamani Sowmiya ◽  
Paramasivam Deepak ◽  
...  
Keyword(s):  
Gold Nanoparticle ◽  
Larvicidal Activity ◽  
Leaf Extract ◽  
Bioactive Components ◽  
Ms Analysis ◽  
Chloroxylon Swietenia
Sign in / Sign up

Export Citation Format

Share Document