scholarly journals Effects of Fresh Watermelon Consumption on the Acute Satiety Response and Cardiometabolic Risk Factors in Overweight and Obese Adults

Nutrients ◽  
2019 ◽  
Vol 11 (3) ◽  
pp. 595 ◽  
Author(s):  
Tiffany Lum ◽  
Megan Connolly ◽  
Amanda Marx ◽  
Joshua Beidler ◽  
Shirin Hooshmand ◽  
...  

Although some studies have demonstrated the beneficial effects of watermelon supplementation on metabolic diseases, no study has explored the potential mechanism by which watermelon consumption improves body weight management. The objective of this study was to evaluate the effects of fresh watermelon consumption on satiety, postprandial glucose and insulin response, and adiposity and body weight change after 4 weeks of intervention in overweight and obese adults. In a crossover design, 33 overweight or obese subjects consumed watermelon (2 cups) or isocaloric low-fat cookies daily for 4 weeks. Relative to cookies, watermelon elicited more (p < 0.05) robust satiety responses (lower hunger, prospective food consumption and desire to eat and greater fullness). Watermelon consumption significantly decreased body weight, body mass index (BMI), systolic blood pressure and waist-to-hip ratio (p ≤ 0.05). Cookie consumption significantly increased blood pressure and body fat (p < 0.05). Oxidative stress was lower at four week of watermelon intervention compared to cookie intervention (p = 0.034). Total antioxidant capacity increased with watermelon consumption (p = 0.003) in blood. This study shows that reductions in body weight, body mass index (BMI), and blood pressure can be achieved through daily consumption of watermelon, which also improves some factors associated with overweight and obesity (clinicaltrials.gov, NCT03380221).

Author(s):  
Tushar Balchand Chudiwal ◽  
Anil Gulingayya Nanjannavar

Background: We investigated the association of body mass index (BMI) measurements in adult hypertensive patients with normal weight and overweight including obesity.Methods: This was a randomized study performed in Udaipur, India, on 200 hypertensive patients aged (32-90) years. Patients were divided according to their body weight (normal weight vs overweight and obesity) into two groups. Weight, height and BMI were measured to estimate the various categories of bodyweight.Results: We found significant relations between body weight and blood pressure. Patients with normal weight had a normal blood pressure. However, a significant increase in blood pressure was observed in patients with overweight and obesity.Conclusions: BMI is related with weight status in hypertensive overweight / obese patients.  


2020 ◽  
Vol 4 (Supplement_2) ◽  
pp. 1693-1693
Author(s):  
Ekamol Tantisattamo ◽  
Natnicha Leelaviwat ◽  
Natchaya Polpichai ◽  
Chawit Lopimpisuth ◽  
Sakditad Saowapa ◽  
...  

Abstract Objectives Overweight and obesity are associated with hypertension (HTN) in renal transplant recipients (RTR). Body weight variability is known to be associated with HTN and poor cardiovascular (CV) outcomes in diabetic patients. After successful kidney transplantation (KT), weight change is very common due partly to perioperative and immunological factors. Association between body weight variability and HTN in RTR is unknown. We hypothesize that high body weight variability is associated with post-transplant HTN. Methods Body weight variability of RTR from a single transplant center was assessed as visit-to-visit body mass index variability (VVBMIV) by using average successive variability (ASV = the average absolute difference between successive values of BMI measured at 4, 12, 24, 36, and 48 weeks after KT). Multi-variable Cox proportional hazard regression analysis was used to examine association between post-transplant VVBMIV and systolic and diastolic HTN (SHTN and DHTN), which are defined as SBP and DBP ≥130 and 80 mmHg, respectively. Results Of 104 RTR, mean ± SD age was 54.29 ± 11.65 years and 62% were female. The majority (36%) were obese followed by normal weight (33%), and overweight (31%). Incidence of SBP was 0.041 person-weeks and median time to event was 12.86 weeks; while the incidence of DBP was 0.036 person-weeks with a slightly longer median time-to-event of 13 weeks. Mean ASV of BMI was 1.26 ± 0.82 kg/m2 (0.47 to 2.18). Risk of SHTN is increased 32% for every 1 kg/m2 increase in VVBMIV (HR 1.32, 95%CI 1.04 to 1.68, P 0.022). After adjusted for age, gender, and their interaction terms, very 1 kg/m2 increase in VVBMIV is associated with a 29% greater risk of developing SHTN (HR 1.29, 95% CI 1.01 to 1.65, P 0.043). However, increase in VVBMIV is not associated with an increased risk of DHTN for both univariable (HR 1.15, 95%CI 0.88 to 1.49, P 0.308) and multi-variable Cox regressions models (HR 1.13, 95%CI 0.86 to 1.49, P 0.391). Conclusions Post-kidney transplant VVBMIV is independently associated post-transplant SHTN, but not DHTN. Further studies is needed to examine mechanism of body weight variability and blood pressure outcomes in RTR. Funding Sources None.


2014 ◽  
Vol 2014 ◽  
pp. 1-5 ◽  
Author(s):  
I. O. Ernest-Nwoke ◽  
M. O. Ozor ◽  
U. Akpamu ◽  
M. O. Oyakhire

Aim. To study the relationship between body mass index (BMI) and blood pressure (BP) on visual acuity among apparently healthy residents of Ekpoma, Esan West Local Government Area of Edo State, Nigeria. Methodology. This is a cross-sectional descriptive study among 225 subjects (ages of 18–35 years) from whom BP, body weight, and height were collected. Visual acuity was measured using the Snellen chart following standard procedures of number of letters seen at 6-metre distance. The data were then analyzed using SPSS version 17. Results. The sampled population consists of 112 male and 113 female (mean age 31.72±14.2 years). Majority (180) of the respondents had normal visual acuity. However, compared with the respondents with normal BMI (R19.61±1.5; L19.67±1.70), visual acuity of underweight (R18.53±2.30; L18.53±2.70) and obese (R15.68±4.79; L17.73±1.70) were more deviated. Similarly, compared with respondent with normal BP (120–125/80–85 mmHg; R18.00±2.53; L18.07±3.11), hypotensive (R15.5±7.35; L15.00±10.20), and hypertensive (R15.01±21.25; L15.00±11.91) respondents had deviated visual acuity. Conclusion. Abnormal body weight (underweight and obese) and BP (hypotension and hypertension) have potential negative impacts on visual acuity. Based on the observed relationship between weights, BP, and visual acuity, eye examinations can be included as regular screening exercise for abnormal BMI and BP conditions.


2021 ◽  
Vol 15 (5) ◽  
pp. 1522-1525
Author(s):  
S. Inayat ◽  
H. F. Khattak ◽  
M. G. Muhammad ◽  
K. Robeen ◽  
A. Inayat ◽  
...  

Objective: The main objective of this study is to determine the efficacy of metformin therapy on clinical and hormonal indices of patients with polycystic ovary syndrome. Study Design: Randomized control trial Place and Duration: Study was conducted at Obstetrics & Gynaecology department of Northwest General Hospital and Research Center, Peshawar and Mian Rashid Hussain Shaheed Memorial Hospital, Pabbi for duration of nine months from March 2020 to November 2020. Methods: Total 100 patients of polycystic ovary syndrome were presented in this study. Patients were aged between 18 to 45years. Patients detailed demographics including age, body mass index and socio-economicstatus were recorded after taking informed written consent. Patients were divided into 2-groups, group I had 50 patients and received metformin (500 mg) three times a day and group II had 50 patients and received pioglitazone (30 mg) three times a day for 3months.Clinical (body weight, blood pressure (BP), and body mass index) and indices fasting blood sugar (FBS), serum triglyceride (TG), cholesterol, low-density lipoprotein, high-density lipoprotein, insulin, testosterone, and dehydroepiandrosterone (DHEA) were measured before and after therapy. Complete data was analyzed by SPSS 22.0 version. Results: Mean age of the patients in group I was 29.18 ± 2.25 years with mean BMI 26.14 ± 8.86 kg/m2 and in group II mean age was 29.8 ± 2.52 years with mean BMI 27.64 ± 7.68 kg/m2.Significantly decrease in blood pressure (systolic 105.41±8.57, diastolic 67.19±8.9), hair loss 20 (40%),oligomenorrhea 23 (46%), body weight 74.45±9.72, waist circumference and dehydroepiandrosterone (DHEA) 2.35±0.67 and as compared to group II. Only triglycerides gave results of reduction in group II 115.39±64.11. Among both groups serum insulin, acne, menstrual disturbance and fasting blood sugar were controlled after treatment. Conclusion: We concluded in this study that use of metformin in patients with polycystic ovary syndrome resulted in to decrease clinical body weight, blood pressure (BP), body mass index and hormonal indices with reduction of serum insulin, acne, menstrual disturbance and fasting blood sugar but pioglitazone was an alternative effective and reliable method in PCOS patients. Keywords: Polycystic ovary syndrome, Insulin resistance, Metformin, Pioglitazone


2019 ◽  
Vol 3 (Supplement_1) ◽  
Author(s):  
Megan Connolly ◽  
Tiffany Lum ◽  
Amanda Marx ◽  
Shirin Hooshmand ◽  
Mark Kern ◽  
...  

Abstract Objectives Watermelon has a great potential in preventing cardiovascular disease (CVD) due to its high levels of fiber, vitamins, minerals, and bioactive constituents such as L-citrulline, lycopene, and beta-carotene. Although previous studies have examined the effects of watermelon juice or extract on risk factors for CVD, it is unknown if the results can be extrapolated to fresh watermelon consumption. This study examined the effects of fresh watermelon consumption on risk factors for CVD in overweight and obese adults. Methods In a crossover design, 33 overweight or obese adults consumed two cups of watermelon or isocaloric low-fat cookies daily for four weeks with a two- to four-week washout period. Body weight, body composition, waist-to-hip ratio, blood pressure, glucose and insulin levels, inflammation, lipid profiles, antioxidant capacity, and liver function markers were measured at baseline and after the interventions. Results Watermelon consumption significantly (P ≤ 0.05) decreased body weight, body mass index (BMI), and systolic blood pressure and waist-to-hip ratio. Cookie consumption significantly increased blood pressure and body fat (P < 0.05). Watermelon intake reduced triglyceride, LDL cholesterol and thiobarbituric acid reactive substances and improved HDL cholesterol and total antioxidant capacity (P < 0.05). Serum glucose, insulin, C-reactive protein, total cholesterol, catalase, and liver function markers were not significantly different between the interventions. Conclusions These findings suggest that daily consumption of fresh watermelon improves lipid profiles and anthropometric measurements, reduces blood pressure, and increases antioxidant capacity, which may have implications for chronic diseases such as CVD. Funding Sources National Watermelon Promotion Board.


2016 ◽  
Vol 41 (3) ◽  
pp. 144-150
Author(s):  
Tahmina Zahan ◽  
Nargis Akhter ◽  
Mohammad Sayadul Islam Mullick ◽  
Zasmin Fauzia

The second generation antipsychotic agents, although exhibit superior safety profile, is associated with metabolic adverse effects including weight gain, diabetes mellitus and hyperlipidaemia. These adverse effects are not only the risk factors for cardiovascular disease and diabetes mellitus but may also impair patient’s adherence to treatment. However, different member of second generation antipsychotics differ in their extent of metabolic adverse effects. The aim of the study was to evaluate the association between olanzapine, risperidone or quetiapine treatment and body mass index, blood pressure, diabetes mellitus and hyperlipidaemia in patients with Schizophrenia and Bipolar Disorder. Forty-four cases of Schizophrenia and Bipolar Disorder diagnosed with DSM-IV criteria were selected according to inclusion and exclusion criteria. Body weight, body mass index and blood pressure were measured at baseline, at the end of 4th, 8th and 12th weeks of treatment. Blood samples were collected to measure blood glucose and serum lipid profile at baseline and at the end of 4th, 8th and 12th weeks in the study group receiving treatment (olanzapine 20-30 mg/day, risperidone 4-16 mg/day and quetiapine 300-800 mg/day) after overnight fasting. Therapeutic use of olanzapine and risperidone in Schizophrenia and Bipolar Disorder for a period of 4th, 8th and 12th weeks was associated with significant increase in body weight and body mass index. Quetiapine did not cause significant changes in body weight and body mass index after 4 and 8 weeks. However, after 12 weeks treatment, body mass index increased significantly. Olanzapine, risperidone and quetiapine increased the blood glucose level significantly after 8 and 12 weeks treatment. Olanzapine and risperidone elevated the serum cholesterol, triglyceride and low density lipoprotein levels significantly after 4, 8 and 12 weeks. But quetiapine showed no significant change in lipid profile. However, olanzapine and risperidone significantly increased triglyceride level after 8 and 12 weeks. Amongst three drugs, quetiapine treatment increased high density lipoprotein level. Our study revealed that quetiapine treatment is associated with less risk of dyslipidaemia.


2017 ◽  
Vol 56 (207) ◽  
pp. 352-356 ◽  
Author(s):  
Saraswati M Padhye

Introduction: High Body Mass Index is one of the risk factors for many chronic diseases and adverse health outcomes. It is associated with an increased risk of coronary heart disease, ischemic stroke, high blood pressure and type 2 diabetes mellitus. It also have many adverse effect on reproductive health of the women like sub fertility, polycystic ovarian disease, menstrual abnormality etc. The purpose of this study is to find Basal Metabolic Rate and the diseases pattern of reproductive age woman in Nepal. Methods: This is a descriptive study of women of reproductive age (15 to 49 years) attending a private gynaecology clinic in Kathmandu Valley from October 2016 to June 2017. Six hundred and eight women of current reproductive age group participated in this study. Women’s particulars and complaints were noted down. Detailed history was taken. Height, weight and blood pressure were recorded and general examination was done. BMI was calculated as BMI is weight in kilogram divided by height in meter square, and it was interpreted as per WHO guidelines. Results: Out of the total 608 participants, 243 (40%) were overweight, 96 (15.8%) were obese. Regarding the common health problems, 154 (25.3%) have sub fertility and 199 (32%) had genitourinary infection. Similarly, 90 (14.8%) had menstrual problems. Conclusions: Prevalence of overweight and obesity has risen significantly comparing to the study done decade ago in same setting. Similarly, sub fertility rate has also risen whereas the prevalence of genitourinary infections has decreased. Keywords: BMI; genitourinary infection; Nepal-reproductive age women; sub fertility.


2007 ◽  
Vol 135 (7-8) ◽  
pp. 440-446 ◽  
Author(s):  
Biljana Beleslin ◽  
Jasmina Ciric ◽  
Milos Zarkovic ◽  
Zorana Penezic ◽  
Svetlana Vujovic ◽  
...  

Introduction Obesity is often accompanied by a number of complications including diabetes mellitus and cardiovascular diseases. Elevated blood pressure and lipids, as well as deterioration of glucoregulation are attributed, as the most significant factors, to development of diabetes mellitus and cardiovascular complications in obese patients. Objective The aim of our study was to evaluate the effects of a fasting diet on blood pressure, lipid profile and glucoregulatory parameters. Method We included 110 patients (33 male and 77 female; mean age 35?1 years, body weight 131.7?2.6 kg, body mass index 45.4?0.8 kg/m2) who were hospitalized for three weeks for the treatment of extreme obesity with the fasting diet. At the beginning, during, and at the end of this period, we evaluated changes in blood pressure, lipid profile, as well as parameters of glucoregulation including glycaemia, insulinaemia, and insulin sensitivity by HOMA. Oral glucose tolerance test (OGTT) was performed in all patients at the beginning and at the end of the fasting diet. Results During the fasting diet, the body weight decreased from 131.7?2.6 kg to 117.7?2.4 kg (p<0.001), the body mass index decreased from 45.4?0.8 kg/m2 to 40.8?0.8 kg/m2 (p<0.001), and both systolic and diastolic blood pressure significantly declined (143?2 vs. 132?2 mm Hg, p<0.001; 92?2 vs. 85?2 mm Hg, p<0.001). In addition, the fasting diet produced a significant decrease in total cholesterol, LDL cholesterol, triglycerides, as well as basal glycaemia and insulinaemia (p<0.001) Before the fasting diet, OGTT was normal in 76% of patients, whereas 21% of patients showed glucose intolerance, and 4% of patients diabetes mellitus. After the fasting diet, OGTT was normal in 88% of patients, whereas 12% of patients still had signs of glucose intolerance (p<0.05). In addition, insulin resistance significantly (p<0.05) increased from 54?6% to 89?13% after the fasting diet. Conclusion The three-week fasting diet in extremely obese patients produced a significant decrease and normalization of blood pressure, decrease in lipids, and improvement in glucoregulation including the increase in insulin sensitivity.


2021 ◽  
Vol 6 (2) ◽  
pp. 1535-1539
Author(s):  
Esha Shrestha ◽  
Shreesh Shrestha ◽  
Prashanna Shrestha ◽  
Nirjala Laxmi Madhikarmi

Introduction: Body mass index is an important parameter associated with a variety of disease processes. The risk of hypertension and cardiovascular diseases increases with an increase in body mass index. The study was conducted to compare the relationship between body mass index and blood pressure. Objective: To evaluate the prevalence and correlate the Obesity and Hypertension in    medical students  Methodology: The study was conducted in 200 students (113 males and 87 females). Height, weight and blood pressure were recorded from all participants and body mass index was calculated. The recorded body mass index was utilized to divide the student into underweight, normal, over weight and obese category according to the World Health organization body mass index classification. Hypertension was determined from the measure of blood pressure. Then comparison of blood pressure with body mass index was made. Results: Among 200 students 6% were obese, 22% were overweight, 65% were normal and 7% underweight. The mean height was 163cm and mean weight 60.48kg. The mean value of systolic blood pressure (105.85, 115.45, 134.95, 137.16 mmHg) and diastolic blood pressure (70.14, 76.15, 90.72, 93.33 mmHg) increased with increasing body mass index. Conclusion: Overweight and obesity increases the risk of hypertension among students.


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