scholarly journals Soybean Bioactive Peptides and Their Functional Properties

Nutrients ◽  
2018 ◽  
Vol 10 (9) ◽  
pp. 1211 ◽  
Author(s):  
Cynthia Chatterjee ◽  
Stephen Gleddie ◽  
Chao-Wu Xiao
Keyword(s):  
Chronic Diseases ◽  
Soy Protein ◽  
Bioactive Peptides ◽  
Soy Proteins ◽  
Health Claim ◽  
Potential Health ◽  
Physiological Functions ◽  
Target Organs ◽  
Soy Peptides ◽  
The Usa

Soy consumption has been associated with many potential health benefits in reducing chronic diseases such as obesity, cardiovascular disease, insulin-resistance/type II diabetes, certain type of cancers, and immune disorders. These physiological functions have been attributed to soy proteins either as intact soy protein or more commonly as functional or bioactive peptides derived from soybean processing. These findings have led to the approval of a health claim in the USA regarding the ability of soy proteins in reducing the risk for coronary heart disease and the acceptance of a health claim in Canada that soy protein can help lower cholesterol levels. Using different approaches, many soy bioactive peptides that have a variety of physiological functions such as hypolipidemic, anti-hypertensive, and anti-cancer properties, and anti-inflammatory, antioxidant, and immunomodulatory effects have been identified. Some soy peptides like lunasin and soymorphins possess more than one of these properties and play a role in the prevention of multiple chronic diseases. Overall, progress has been made in understanding the functional and bioactive components of soy. However, more studies are required to further identify their target organs, and elucidate their biological mechanisms of action in order to be potentially used as functional foods or even therapeutics for the prevention or treatment of chronic diseases.

scholarly journals Food-Derived Bioactive Peptides in Human Health: Challenges and Opportunities

Nutrients ◽  
2018 ◽  
Vol 10 (11) ◽  
pp. 1738 ◽  
Author(s):  
Subhadeep Chakrabarti ◽  
Snigdha Guha ◽  
Kaustav Majumder
Keyword(s):  
Bioactive Peptides ◽  
Scientific Evidence ◽  
Bioactive Peptide ◽  
Health Claims ◽  
Commercial Application ◽  
Potential Health ◽  
Physiological Functions ◽  
Wide Range ◽  
Challenges And Opportunities ◽  
Production Techniques

Recent scientific evidence suggests that food proteins not only serve as nutrients, but can also modulate the body’s physiological functions. These physiological functions are primarily regulated by some peptides that are encrypted in the native protein sequences. These bioactive peptides can exert health beneficial properties and thus are considered as a lead compound for the development of nutraceuticals or functional foods. In the past few decades, a wide range of food-derived bioactive peptide sequences have been identified, with multiple health beneficial activities. However, the commercial application of these bioactive peptides has been delayed because of the absence of appropriate and scalable production methods, proper exploration of the mechanisms of action, high gastro-intestinal digestibility, variable absorption rate, and the lack of well-designed clinical trials to provide the substantial evidence for potential health claims. This review article discusses the current techniques, challenges of the current bioactive peptide production techniques, the oral use and gastrointestinal bioavailability of these food-derived bioactive peptides, and the overall regulatory environment.

scholarly journals Determinants of COVID-19 preventive behaviours among adults with chronic diseases in the USA: an analysis of the nationally representative COVID-19 impact survey

BMJ Open ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. e044600
Author(s):  
Jessica Y. Islam ◽  
Denise C. Vidot ◽  
Marlene Camacho-Rivera
Keyword(s):  
Chronic Diseases ◽  
Rural Areas ◽  
Prevalence Ratio ◽  
Face Mask ◽  
Chronic Obstructive ◽  
Cross Sectional ◽  
Obstructive Pulmonary Disease ◽  
High School Degree ◽  
The Usa ◽  
Nationally Representative

BackgroundPreventive behaviours have been recommended to control the spread of SARS-CoV-2. Adults with chronic diseases (CDs) are at higher risk of COVID-19-related mortality compared to the general population. Our objective was to evaluate adherence to COVID-19 preventive behaviours among adults without CDs compared with those with CDs and identify determinants of non-adherence to COVID-19 preventive behaviours.Study designCross-sectional.Setting and participantsWe used data from the nationally representative COVID-19 Impact Survey (n=10 760) conducted in the USA.Primary measuresAdults with CDs were categorised based on a self-reported diagnosis of diabetes, high blood pressure, heart disease/heart attack/stroke, asthma, chronic obstructive pulmonary disease (COPD), bronchitis or emphysema, cystic fibrosis, liver disease, compromised immune system, or cancer (54%).ResultsCompared with adults without CDs, adults with CDs were more likely to adhere to preventive behaviours including wearing a face mask (χ2-p<0.001), social distancing (χ2-p<0.001), washing or sanitising hands (χ2-p<0.001), and avoiding some or all restaurants (χ2-p=0.002) and public or crowded places (χ2-p=0.001). Adults with a high school degree or below [Adjusted prevalence ratio (aPR):1.82, 95% Confidence interval (CI)1.04 to 3.17], household income <US$50 000 (aPR:2.03, 95% CI 1.34 to 2.72), uninsured (aPR:1.65, 95% CI1.09 to 2.52), employed (aPR:1.48, 95% CI 1.02 to 2.17), residing in rural areas (aPR:1.70, 95% CI 1.01 to 2.85) and without any CD (aPR:1.78, 95% CI 1.24 to 2.55) were more likely to not adhere to COVID-19 preventive behaviours.ConclusionAdults with CDs are more likely to adhere to recommended COVID-19 preventive behaviours. Public health messaging targeting specific demographic groups and geographic areas, such as adults without CD or adults living in rural areas, should be prioritised.

scholarly journals Increasing presence of xylazine in heroin and/or fentanyl deaths, Philadelphia, Pennsylvania, 2010–2019

2021 ◽  
pp. injuryprev-2020-043968
Author(s):  
Jewell Johnson ◽  
Lia Pizzicato ◽  
Caroline Johnson ◽  
Kendra Viner
Keyword(s):  
Public Health ◽  
United States ◽  
Drug Users ◽  
Active Drug ◽  
Illicit Drug ◽  
Adverse Outcomes ◽  
Drug Supply ◽  
Health Consequences ◽  
Potential Health ◽  
The Usa

Reports from active drug users state that xylazine, the veterinary tranquilliser, has been increasing in the illicit drug supply in Philadelphia. To describe trends and characteristics of unintentional deaths from heroin and/or fentanyl overdose with xylazine detections occurring in Philadelphia, Pennsylvania, the Philadelphia Department of Public Health analysed data on deaths from unintentional heroin and/or fentanyl overdose from the Philadelphia Medical Examiner’s Office over a 10-year period (2010–2019). Xylazine went from being detected in less than 2% cases of fatal heroin and/or fentanyl overdose between 2010 and 2015 to 262 (31%) of the 858 fatal heroin and/or fentanyl overdose cases in 2019. Currently, information is limited on the presence of xylazine in continental United States. Xylazine’s association with adverse outcomes in other locations indicates that potential health consequences should also be monitored in the USA. Whenever possible, jurisdictions should consistently test for xylazine.

Bioactive Peptides Derived from Soy Protein

2005 ◽  
pp. 225-233
Author(s):  
Masaaki Yoshikawa ◽  
Takahiro Tsuruki
Keyword(s):  
Soy Protein ◽  
Bioactive Peptides

Encapsulated sour cherry pomace extract: Effect on the colour and rheology of cookie dough

2018 ◽  
Vol 25 (2) ◽  
pp. 130-140 ◽  
Author(s):  
Jovana Petrović ◽  
Biljana Pajin ◽  
Ivana Lončarević ◽  
Vesna Tumbas Šaponjac ◽  
Ivana Nikolić ◽  
...  
Keyword(s):  
Rheological Properties ◽  
Wheat Flour ◽  
Soy Protein ◽  
Loss Modulus ◽  
Control Sample ◽  
Sour Cherry ◽  
Soy Proteins ◽  
Blue Colour ◽  
B Values ◽  
Cherry Pomace

In this study, the effect of encapsulated sour cherry pomace extract on the physical characteristics of the cookie dough (colour, textural and rheological properties) was investigated. Sour cherry pomace extract encapsulated in whey (WE) and soy proteins (SE) was incorporated in cookie dough, replacing 10% (WE10 and SE10) and 15% (WE15 and SE15) of wheat flour. The dough samples containing encapsulates had the grey-blue colour ( b* values significantly decreased compared to control sample). Due to the presence of anthocyanins, a* values of the dough colour increased significantly with the addition of encapsulates. The addition of soy protein encapsulate increased hardness, resistance to extension and viscosity of cookie dough and decreased deformation compliance ( J), while the addition of whey encapsulate caused dough softness, higher deformation compliance and lower values of viscosity compared to control sample. Values of storage and loss modulus, G′ and G″, significantly decreased when wheat flour was replaced with WE and increased when the flour was replaced with soy protein encapsulate. The addition of soy protein encapsulate resulted in higher cookie hardness.

scholarly journals Nutraceutical potentials of synergic foods: a systematic review

2019 ◽  
Vol 6 (1) ◽  
Author(s):  
Tharani Devi Natarajan ◽  
Janci Rani Ramasamy ◽  
Kirthika Palanisamy
Keyword(s):  
Chronic Diseases ◽  
Health Benefits ◽  
Nutrient Deficiency ◽  
Value Added ◽  
Well Being ◽  
Active Role ◽  
The Body ◽  
Health Food ◽  
Potential Health ◽  
Nutrition Research

AbstractFood synergy is a concept of linking foods to health. Food consists of mixtures of nutrients, serving as a fuel for the body. When synergistic foods are put together, the evidence for potential health benefits becomes stronger than individual foods. Nutrient deficiency is a known phenomenon in many individuals, and synergy plays a very important role in combating the nutritional deficiency. Today’s consumer expresses high interest to build knowledge on the active role of food in their well-being, as well as in the prevention of non-transmissible chronic diseases. Functional foods and their active compounds play a vital role in preventing chronic diseases, improving immunity, and decreasing infections. The concept of synergy is an overthinking in nutrition research which can enhance effective dietary planning value added to the forthcoming nutrition research. This paper gives an overview of various synergic combinations of food components and their interactions within the food and with the human system to attain ideal health benefits.

scholarly journals BIOPEP-UWM Database of Bioactive Peptides: Current Opportunities

2019 ◽  
Vol 20 (23) ◽  
pp. 5978 ◽  
Author(s):  
Minkiewicz ◽  
Iwaniak ◽  
Darewicz
Keyword(s):  
Amino Acids ◽  
Amino Acid ◽  
Chronic Diseases ◽  
Bioactive Peptides ◽  
Protein Sequences ◽  
Batch Processing ◽  
Amino Acid Sequences ◽  
Quantitative Parameters ◽  
New Information

The BIOPEP-UWM™ database of bioactive peptides (formerly BIOPEP) has recently become a popular tool in the research on bioactive peptides, especially on these derived from foods and being constituents of diets that prevent development of chronic diseases. The database is continuously updated and modified. The addition of new peptides and the introduction of new information about the existing ones (e.g., chemical codes and references to other databases) is in progress. New opportunities include the possibility of annotating peptides containing D-enantiomers of amino acids, batch processing option, converting amino acid sequences into SMILES code, new quantitative parameters characterizing the presence of bioactive fragments in protein sequences, and finding proteinases that release particular peptides.

scholarly journals Leadership and chronic diseases: a bibliometric review

2019 ◽  
Vol 29 (Supplement_4) ◽  
Author(s):  
M Cabral ◽  
G Daminani
Keyword(s):  
Chronic Diseases ◽  
Leadership Role ◽  
Religious Communities ◽  
Mesh Terms ◽  
The Usa ◽  
Bibliometric Review ◽  
The One ◽  
The Uk ◽  
Health Field

Abstract Background Leadership and chronic diseases are two frequent topics in current public health discussions. We performed a bibliometric analysis to study what interactions exist between these two themes. This study allows an insight on what is being published and also identifies potential gaps that need to be addressed. Methods We have reviewed all the titles and abstracts of articles available at PUBMED with the MESH terms ’Leadership’ and ’Chronic Disease’. We collected information about the authors, year, journal and type of publication and country where the study was done. We have also done a qualitative analysis on the themes addressed. Results We have found 171 entries, of witch 85 (49,7%) referred to apparent peer reviewed studies in English. All other publications referred to editorials, commentaries or the PUBMED entry did not allow for greater clarification. From 1998 the publication of articles became regular, with a peak of 14 articles published in 2014. The average of authors per publication was 3,19. The most frequent country involved was the USA (62), follow by the UK (14), Canada (11) and Australia (10). 128 publications were identified, of which BMC Health Serv Res was the one with the highest number of articles included (5). There was some form of a call for greater leadership from nurses in 22 articles. We also highlight 5 articles that called for a greater role of pastors and religious communities in this field. Conclusions Despite the perception of being common topics, there is still a low rate of publication of studies in the field of leadership and chronic diseases. There is a predominance of articles from the USA. There was not a predominant publication in this field. Despite doctors being typically seen as the leaders within the health field, the articles included seem to point to a trend in calling for a bigger leadership role of other actors, such as nurses. Key messages There is a need for more research in the field of leadership in chronic diseases. There seems to be a trend calling for greater leadership in the field from non-physician actors.

scholarly journals Seoul Virus Tropism and Pathology in Naturally Infected Feeder Rats

Viruses ◽  
2019 ◽  
Vol 11 (6) ◽  
pp. 531 ◽  
Author(s):  
Miriam Maas ◽  
Melanie van Heteren ◽  
Ankje de Vries ◽  
Thijs Kuiken ◽  
Tabitha Hoornweg ◽  
...  
Keyword(s):  
Natural Infection ◽  
Virus Transmission ◽  
Hemorrhagic Fever ◽  
Histopathological Analysis ◽  
Cell Tropism ◽  
Adult Rats ◽  
Seoul Virus ◽  
Target Organs ◽  
The Usa ◽  
Histopathologic Changes

Seoul virus (SEOV) is a zoonotic orthohantavirus carried by black and brown rats, and can cause hemorrhagic fever with renal syndrome in humans. Human cases of SEOV virus infection have most recently been reported in the USA, United Kingdom, France and the Netherlands and were primarily associated with contact with pet rats and feeder rats. Infection of rats results in an asymptomatic but persistent infection. Little is known about the cell tropism of SEOV in its reservoir and most available data is based on experimental infection studies in which rats were inoculated via a route which does not recapitulate virus transmission in nature. Here we report the histopathological analysis of SEOV cell tropism in key target organs following natural infection of a cohort of feeder rats, comprising 19 adults and 11 juveniles. All adult rats in this study were positive for SEOV specific antibodies and viral RNA in their tissues. One juvenile rat was seropositive, but negative in the rRT-PCR. Of the 19 adult rats of which subsequently additional organs were tested, SEOV RNA was detected in all lungs, followed by kidney (79%) and liver (74%). Histopathologic changes associated with SEOV infection were primarily found in the liver, consistent with a pathological diagnosis of a mild hepatitis. In conclusion, natural SEOV infection results in mild inflammation of the liver in the absence of clinical disease.

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