scholarly journals The Effect of Digestion and Digestibility on Allergenicity of Food

Nutrients ◽  
2018 ◽  
Vol 10 (9) ◽  
pp. 1129 ◽  
Author(s):  
Isabella Pali-Schöll ◽  
Eva Untersmayr ◽  
Martina Klems ◽  
Erika Jensen-Jarolim
Keyword(s):  
Food Allergy ◽  
Gastrointestinal Tract ◽  
Immune Tolerance ◽  
Food Processing ◽  
Life Style ◽  
Dietary Habits ◽  
Nutrient Supply ◽  
Contributing Factors ◽  
Food Allergenicity ◽  
Allergy Prevalence

Food allergy prevalence numbers are still on the rise. Apart from environmental influences, dietary habits, food availability and life-style factors, medication could also play a role. For immune tolerance of food, several contributing factors ensure that dietary compounds are immunologically ignored and serve only as source for energy and nutrient supply. Functional digestion along the gastrointestinal tract is essential for the molecular breakdown and a prerequisite for appropriate uptake in the intestine. Digestion and digestibility of carbohydrates and proteins thus critically affect the risk of food allergy development. In this review, we highlight the influence of amylases, gastric acid- and trypsin-inhibitors, as well as of food processing in the context of food allergenicity.

scholarly journals Mechanisms Underlying the Skin-Gut Cross Talk in the Development of IgE-Mediated Food Allergy

Nutrients ◽  
2020 ◽  
Vol 12 (12) ◽  
pp. 3830
Author(s):  
Marloes van Splunter ◽  
Liu Liu ◽  
R.J. Joost van Neerven ◽  
Harry J. Wichers ◽  
Kasper A. Hettinga ◽  
...  
Keyword(s):  
Food Allergy ◽  
Gastrointestinal Tract ◽  
Immune Tolerance ◽  
Allergic Sensitization ◽  
Therapeutic Strategies ◽  
Dietary Proteins ◽  
Oral Ingestion ◽  
Food Antigens ◽  
Ige Mediated ◽  
Gastrointestinal Inflammation

Immune-globulin E (IgE)-mediated food allergy is characterized by a variety of clinical entities within the gastrointestinal tract, skin and lungs, and systemically as anaphylaxis. The default response to food antigens, which is antigen specific immune tolerance, requires exposure to the antigen and is already initiated during pregnancy. After birth, tolerance is mostly acquired in the gut after oral ingestion of dietary proteins, whilst exposure to these same proteins via the skin, especially when it is inflamed and has a disrupted barrier, can lead to allergic sensitization. The crosstalk between the skin and the gut, which is involved in the induction of food allergy, is still incompletely understood. In this review, we will focus on mechanisms underlying allergic sensitization (to food antigens) via the skin, leading to gastrointestinal inflammation, and the development of IgE-mediated food allergy. Better understanding of these processes will eventually help to develop new preventive and therapeutic strategies in children.

scholarly journals Fighting Food Allergy by Inducing Oral Tolerance: Facts and Fiction

2021 ◽  
pp. 1-11
Author(s):  
Xiaotong Yang ◽  
Rui Liang ◽  
Qianlu Xing ◽  
Xiaojuan Ma
Keyword(s):  
Food Allergy ◽  
Immune System ◽  
Gastrointestinal Tract ◽  
Gut Microbiota ◽  
Food Processing ◽  
Oral Tolerance ◽  
Accidental Exposure ◽  
Related Factors ◽  
Processing Methods ◽  
Food Antigens

The prevalence of food allergy (FA) is increasing, and there is an urgent need to take effective measures against it. One important measure is the avoidance diet, which shows a disadvantage, especially in case of accidental exposure. Oral tolerance restoration sheds new light on the control of FA. Oral tolerance is naturally a state of systemic unresponsiveness of the gastrointestinal tract to food antigens and its restoration can be a clinical therapy for FA. Its immune basis lies on the intestinal mucosal immune system and factors, such as gut microbiota and food processing methods, are also important. This review presents recent advances in oral tolerance and its closely related factors.

Obesity in Children - An alarming problem in Kaumarbhritya

2017 ◽  
Vol 2 (4) ◽  
Author(s):  
Sharma Shilpi ◽  
Sharma Rakesh ◽  
Bhima Devi ◽  
Asharafi Bakhtyar
Keyword(s):  
Body Weight ◽  
Childhood Obesity ◽  
Life Style ◽  
Dietary Habits ◽  
The Body ◽  
Continuous Change ◽  
Body Activity ◽  
Obesity In Children ◽  
At Home

A roly-poly child obviously attracts many attentions but if the trend remains unchanged it could be a reason of worry as this is the primitive sign of childhood obesity which is the leading problem in today’s era. With continuous change in life style and dietary habits, child has become the victim of many diseases and obesity (Sthaulya) is one of them. There are and were some human activists talking about reducing the weight of study bags; but none is thinking about the weight our babies are carrying. In present era both parents are working, to earn the luxuries and amusements, so the kids are left with the food packets at home with idiot boxes to see some “de-shaped” cartoons resulting in the reduction of healthy nutritious diet and also reducing their body activity. The body weight of our babies is putting pressure on their “cuteness”, their “happiness”, their “emotions” and on their “being”. In Ayurveda it needs step by step examination and treatment to break the ‘Dushtasamprapti Chakra’ of Sthaulya by both non pharmacological such as Yoga and pharmacological remedies such as Panchakarma therapy, Shamana therapy etc. to achieve the goal.

scholarly journals Food allergy: nuts and tree nuts

2006 ◽  
Vol 96 (S2) ◽  
pp. S95-S102 ◽  
Author(s):  
Jesus F. Crespo ◽  
John M. James ◽  
Consuelo Fernandez-Rodriguez ◽  
Julia Rodriguez
Keyword(s):  
Food Allergy ◽  
Dietary Habits ◽  
Storage Proteins ◽  
Seed Storage ◽  
Seed Storage Proteins ◽  
Cross Reactivity ◽  
Severe Reaction ◽  
Immunological Mechanism ◽  
Pathogenesis Related Protein ◽  
The Usa

Nuts are a well-defined cause of food allergy, which affect approximately 1 % of the general population in the UK and the USA. There do appear to be differences in the frequency of nut allergy between different countries because of different dietary habits and cooking procedures. For example, in the USA and France, peanuts are one of the most frequent causes of food allergy, but in other countries, it seems to be less common. Genetic factors, in particular, appear to play a role in the development of peanut allergy. While the majority of nut allergens are seed storage proteins, other nut allergens are profilins and pathogenesis-related protein homologues, considered as panallergens because of their widespread distribution in plants. The presence of specific IgE antibodies to several nuts is a common clinical finding, but the clinical relevance of this cross-reactivity is usually limited. Allergic reactions to nuts appear to be particularly severe, sometimes even life-threatening, and fatal reactions following their ingestion have been documented. Food allergy is diagnosed by identifying an underlying immunological mechanism (i.e. allergic testing), and establishing a causal relationship between food ingestion and symptoms (i.e. oral challenges). In natural history investigations carried out in peanut-allergic children, approximately 20 % of the cases outgrew their allergy or developed oral tolerance. The treatment of nut allergies should include patient and family education about avoiding all presentations of the food and the potential for a severe reaction caused by accidental ingestion. Patients and families should be instructed how to recognise early symptoms of an allergic reaction and how to treat severe anaphylaxis promptly.

THE PHYSILOGICAL CONCEPT OF AGNI AND TRIDOSH WITH REFERENCE TO GRAHANI, A LITERARY REVIEW

2020 ◽  
Vol 8 (02) ◽  
Author(s):  
Vrushali P. Kale Vrushali Purushottam Kale
Keyword(s):  
Gastrointestinal Tract ◽  
Life Style ◽  
Food Habits ◽  
Digestive System ◽  
The Body ◽  
Main Role ◽  
Classical Literature ◽  
Root Cause ◽  
Digestion Process ◽  
Physiological Analysis

According to Ayurveda, Jatharagni plays main role in the digestion process. Jatharagni carries its functions through Pachaka pitta. Grahani is an organ of gastrointestinal tract located between Amashaya and Pakwashaya, where digestion takes place. According to classical literature Pitta is same as Agni. Tridosha also plays very important role in the digestion process. In the recent days, irregular life style affects the digestive system and Jatharagni very badly. Whenever Agni gets (Vikrut) unbalanced due to wrong food habits and lifestyle, it should be understood that along with Agni, Pachaka Pitta will also get disturbed. Agnimandya is the root cause of most of the disorders like Grahani. Grahani organ is the main location of Jatharagni. Grahani is the organ where Pachak Pitta and Samanvayu carry out digestion. The most important function of Grahani is digestion of food with the help of Jatharagni, Pachakpitta, Pittadhara Kala and Samnvayu. Agni inside the body, digest the food give strength and maintain health. Samanvayu regulates the movements of the Grahani and helps in digestion. Hence, in this article we attempt to analyze and correlate patho-physiology of Grahani with respect to Physiological analysis of Agni and disturbed doshas. Etiological factors induces imbalance in Jatharagni, Pachak Pitta and Samanvayu and prolonged imbalance state weakens the Pittadhara Kala, which results in disease Grahani. Health of Grahani entirely depends on balanced state of Jatharagni, Pachaka Pitta, Pittadhara Kala and Samanvayu. The irregular life style, incompatible food habits creates Ama causes Grahani, affecting the digestive system and Jatharagni very badly.

scholarly journals Ayurveda Internal Medicine for the Management of Common Metabolic Disorders W.S.R. to Madhumeha and Sthoulya

2019 ◽  
Vol 9 (5-s) ◽  
pp. 167-169
Author(s):  
Dhananjay S. Khot
Keyword(s):  
Internal Medicine ◽  
Metabolic Syndrome ◽  
Life Style ◽  
Metabolic Disorders ◽  
Dietary Habits ◽  
Metabolic Diseases ◽  
Health Issues ◽  
The Metabolic Syndrome ◽  
Sedentary Life Style

The metabolic disorders are major health issues of today’s scenario and incidences of metabolic diseases increases day by day due to the disturbed pattern of life style. Ayurveda texts have described term “Santarpanjanya Vikaras” which resembles diseases of defective tissue metabolism. Ayurveda mentioned that improper dietary habits and sedentary life style affects state of Agni which resulted Ama production and finally leading to the metabolic syndrome. The vitiation of Dosha, diminish state of Dhatu and blockage of channels, etc. also can initiate pathogenesis of metabolic disorders. The Kayachikitsa branch of Ayurveda recommended use of internal medicine for the management of various metabolic disorders. Considering increased health burden of society due to the metabolic syndrome present article explore role of ayurveda internal medicine for the management of metabolic syndrome. Keywords: Ayurveda, metabolic syndrome, Santarpanjanya, Madhumeha and Sthoulya.       

scholarly journals AYURVEDIC DIETARY CONCEPTS IN DIFFERENT AGE GROUP OF CHILDREN

2020 ◽  
pp. 84-86
Author(s):  
Shamama Firdaus ◽  
Sunil Topre ◽  
Nitin Mane
Keyword(s):  
Life Style ◽  
Dietary Habits ◽  
Age Groups ◽  
Healthy Person ◽  
The Body ◽  
Developmental Phase ◽  
Age Group ◽  
Factors Influencing ◽  
Healthy Nutrition ◽  
Major Factors

Ayurveda is a science of life, which mainly aims to promote and preserve the health of the individuals. In this techno and competitive era, life style and diet are major factors influencing the health of the individuals. Diet and dietary habits play important role in maintenance of health. Ayurveda, its main aim is to promote and preserve the health, strength and longevity of healthy person and to cure the disease. Ayurveda places special emphasis on Ahara and believes that healthy nutrition nourishes the Sharir, Mana, Atma. As Acharyas has described Ahara. Nidra, Brahmcharya are Tryoupsthambha (sub pillars) which support the body itself. Here Ahara has been placed first which shows that it is most important to maintain and sustain of life. Children are delicate and most sensitive and prone to the infectious diseases. They are miniature of adult. They are in Ajatvyajanawastha (developing stage). Psychologically they are innocent. Being in developmental phase, Ahara plays very important role in the life of children. So parents should be aware of dietetic components required by child in different age groups.

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