scholarly journals Multi-Purpose Nanovoid Array Plasmonic Sensor Produced by Direct Laser Patterning

Nanomaterials ◽  
2019 ◽  
Vol 9 (10) ◽  
pp. 1348 ◽  
Author(s):  
Dmitrii V. Pavlov ◽  
Alexey Yu. Zhizhchenko ◽  
Mitsuhiro Honda ◽  
Masahito Yamanaka ◽  
Oleg B. Vitrik ◽  
...  
Keyword(s):  
Field Enhancement ◽  
Normal Incidence ◽  
Resonance Wavelength ◽  
Label Free ◽  
Plasmonic Sensor ◽  
Thin Glass ◽  
Laser Patterning ◽  
Near Ir ◽  
Direct Laser ◽  
Vibration Spectroscopy

We demonstrate a multi-purpose plasmonic sensor based on a nanovoid array fabricated via inexpensive and highly-reproducible direct femtosecond laser patterning of thin glass-supported Au films. The proposed nanovoid array exhibits near-IR surface plasmon (SP) resonances, which can be excited under normal incidence and optimised for specific applications by tailoring the array periodicity, as well as the nanovoid geometric shape. The fabricated SP sensor offers competitive sensitivity of ≈ 1600 nm/RIU at a figure of merit of 12 in bulk refractive index tests, as well as allows for identification of gases and ultra-thin analyte layers, making the sensor particularly useful for common bioassay experiments. Moreover, isolated nanovoids support strong electromagnetic field enhancement at lattice SP resonance wavelength, allowing for label-free molecular identification via surface-enhanced vibration spectroscopy.

scholarly journals Multi-Purpose Nanovoid Array Plasmonic Sensor Produced by Direct Laser Patterning

2019 ◽  
Author(s):  
Dmitrii V. Pavlov ◽  
Alexey Yu. Zhizhchenko ◽  
Mitsuhiro Honda ◽  
Masahito Yamanaka ◽  
Oleg B. Vitrik ◽  
...  
Keyword(s):  
Field Enhancement ◽  
Normal Incidence ◽  
Resonance Wavelength ◽  
Label Free ◽  
Plasmonic Sensor ◽  
Thin Glass ◽  
Laser Patterning ◽  
Near Ir ◽  
Direct Laser ◽  
Vibration Spectroscopy

We demonstrate a multi-purpose plasmonic sensor based on nanovoid array fabricated via inexpensive and highly reproducible direct femtosecond laser patterning of thin glass-supported Au films. The proposed nanovoid array exhibits near-IR surface plasmon (SP) resonances, which can be excited under normal incidence and optimised for specific application by tailoring array periodicity as well as nanovoid geometric shape. Fabricated SP sensor offers competitive sensitivity of about 1600 nm/RIU at a figure of merit of 12 in bulk refractive index tests, as well as allows for identification of gases and ultra-thin analyte layers making the sensor particularly useful for common bioassay experiments. Moreover, isolated nanovoids support strong electromagnetic field enhancement at lattice SP resonance wavelength, allowing for label-free molecular identification via surface-enhanced vibration spectroscopy.

scholarly journals Ultrasensitive SERS-Based Plasmonic Sensor with Analyte Enrichment System Produced by Direct Laser Writing

Nanomaterials ◽  
2019 ◽  
Vol 10 (1) ◽  
pp. 49 ◽  
Author(s):  
Georgii Pavliuk ◽  
Dmitrii Pavlov ◽  
Eugeny Mitsai ◽  
Oleg Vitrik ◽  
Aleksandr Mironenko ◽  
...  
Keyword(s):  
High Performance ◽  
Organic Dyes ◽  
Medical Diagnostics ◽  
Water Repellent ◽  
Label Free ◽  
Plasmonic Sensor ◽  
Active Sensor ◽  
Direct Laser ◽  
Surface Enhanced Raman ◽  
Analyte Enrichment

We report an easy-to-implement device for surface-enhanced Raman scattering (SERS)-based detection of various analytes dissolved in water droplets at trace concentrations. The device combines an analyte-enrichment system and SERS-active sensor site, both produced via inexpensive and high-performance direct femtosecond (fs)-laser printing. Fabricated on a surface of water-repellent polytetrafluoroethylene substrate as an arrangement of micropillars, the analyte-enrichment system supports evaporating water droplet in the Cassie–Baxter superhydrophobic state, thus ensuring delivery of the dissolved analyte molecules towards the hydrophilic SERS-active site. The efficient pre-concentration of the analyte onto the sensor site based on densely arranged spiky plasmonic nanotextures results in its subsequent label-free identification by means of SERS spectroscopy. Using the proposed device, we demonstrate reliable SERS-based fingerprinting of various analytes, including common organic dyes and medical drugs at ppb concentrations. The proposed device is believed to find applications in various areas, including label-free environmental monitoring, medical diagnostics, and forensics.

scholarly journals Ultrasensitive SERS-Based Plasmonic Sensor with Analyte Enrichment System Produced by Direct Laser Writing

2019 ◽  
Author(s):  
George Pavliuk ◽  
Dmitrii Pavlov ◽  
Eugeny Mitsai ◽  
Oleg Vitrik ◽  
Aleksandr Mironenko ◽  
...  
Keyword(s):  
High Performance ◽  
Organic Dyes ◽  
Medical Diagnostics ◽  
Water Repellent ◽  
Label Free ◽  
Plasmonic Sensor ◽  
Active Sensor ◽  
Direct Laser ◽  
Analyte Enrichment ◽  
Trace Concentrations

We report an easy-to-implement device for SERS-based detection of various analytes dissolved in water droplets at trace concentrations. The device combines an analyte-enrichment system and SERS-active sensor site, both produced via inexpensive and high-performance direct fs-laser printing. Fabricated on a surface of water-repellent polytetrafluoroethylene substrate as an arrangement of micropillars, the analyte-enrichment system supports evaporating water droplet in the Cassie-Baxter superhydrophobic state, thus ensuring delivery of the dissolved analyte molecules towards the hydrophilic SERS-active site. The efficient pre-concentration of the analyte onto the sensor site based on densely-arranged spiky plasmonic nanotextures results in its subsequent label-free identification by means of SERS spectroscopy. Using the proposed device, we demonstrate reliable SERS-based fingerprinting of various analytes, including common organic dyes and medical drugs at ppb concentrations. The proposed device is believed to find applications in various areas, including label-free environmental monitoring, medical diagnostics, and forensics.

Direct Laser Patterning of a 2D WSe 2 Logic Circuit

2021 ◽  
pp. 2009549
Author(s):  
Chao Zhu ◽  
Xiaoxu Zhao ◽  
Xiaowei Wang ◽  
Jieqiong Chen ◽  
Peng Yu ◽  
...  
Keyword(s):  
Logic Circuit ◽  
Laser Patterning ◽  
Direct Laser

Plasmonic Sensor Could Enable Label-Free DNA Sequencing

ACS Sensors ◽  
2018 ◽  
Vol 3 (3) ◽  
pp. 561-568 ◽  
Author(s):  
Arif E. Cetin ◽  
Pinar Iyidogan ◽  
Yuki Hayashi ◽  
Mark Wallen ◽  
Kandaswamy Vijayan ◽  
...  
Keyword(s):  
Dna Sequencing ◽  
Label Free ◽  
Plasmonic Sensor ◽  
Free Dna

Monitoring the effects of chemical stimuli on live cells with metasurface-enhanced infrared reflection spectroscopy

2021 ◽  
Author(s):  
Steven H. Huang ◽  
Jiaruo Li ◽  
Zhiyuan Fan ◽  
Robert Delgado ◽  
Gennady Shvets
Keyword(s):  
Intracellular Signaling ◽  
Strong Field ◽  
Detection System ◽  
Field Enhancement ◽  
Chemical Imaging ◽  
Live Cells ◽  
Label Free ◽  
Reflection Spectroscopy ◽  
Infrared Reflection ◽  
Infrared Reflection Spectroscopy

Infrared spectroscopy has found wide applications in the analysis of biological materials. A more recent development is the use of engineered nanostructures, or plasmonic metasurfaces, as substrates for metasurface-enhanced infrared reflection spectroscopy (MEIRS). Here, we demonstrate that strong field enhancement from plasmonic metasurfaces enables the use of MEIRS as a highly informative analytic technique for real-time monitoring of cells. By exposing live cells cultured on a plasmonic metasurface to chemical compounds, we show that MEIRS can be used as a label-free phenotypic assay for detecting multiple cellular responses to external stimuli: changes in cell morphology, adhesion, lipid composition of the cellular membrane, as well as intracellular signaling. Using a focal plane array detection system, we show that MEIRS also enables spectro-chemical imaging at the single-cell level. The described metasurface-based all-optical sensor opens the way to a scalable, high-throughput spectroscopic assay for live cells.

scholarly journals Application of a Terahertz System Combined with an X-Shaped Metamaterial Microfluidic Cartridge

Micromachines ◽  
2020 ◽  
Vol 11 (1) ◽  
pp. 74
Author(s):  
Shih-Ting Huang ◽  
Shen-Fu Hsu ◽  
Kai-Yuan Tang ◽  
Ta-Jen Yen ◽  
Da-Jeng Yao
Keyword(s):  
Far Infrared ◽  
Infrared Region ◽  
Microfluidic System ◽  
Electromagnetic Response ◽  
Thz Radiation ◽  
Similar Species ◽  
Label Free ◽  
Plasmonic Sensor ◽  
Molecular Fingerprint ◽  
Highly Sensitive Detection

Terahertz (THz) radiation has attracted wide attention for its ability to sense molecular structure and chemical matter because of a label-free molecular fingerprint and nondestructive properties. When it comes to molecular recognition with terahertz radiation, our attention goes first towards the absorption spectrum, which is beyond the far infrared region. To enhance the sensitivity for similar species, however, it is necessary to apply an artificially designed metamaterial sensor for detection, which confines an electromagnetic field in an extremely sub-wavelength space and hence receives an electromagnetic response through resonance. Once the resonance is caused through the interaction between the THz radiation and the metamaterial, a minute variation might be observed in the frequency domain. For a geometric structure of a metamaterial, a novel design called an X-shaped plasmonic sensor (XPS) can create a quadrupole resonance and lead to sensitivity greater than in the dipole mode. A microfluidic system is able to consume reagents in small volumes for detection, to diminish noise from the environment, and to concentrate the sample into detection spots. A microfluidic device integrated with an X-shaped plasmonic sensor might thus achieve an effective and highly sensitive detection cartridge. Our tests involved not only measurements of liquid samples, but also the performance of a dry bio-sample coated on an XPS.

scholarly journals Second Harmonic Generation from Phase-Engineered Metasurfaces of Nanoprisms

Micromachines ◽  
2020 ◽  
Vol 11 (9) ◽  
pp. 848 ◽  
Author(s):  
Kanta Mochizuki ◽  
Mako Sugiura ◽  
Hirofumi Yogo ◽  
Stefan Lundgaard ◽  
Jingwen Hu ◽  
...  
Keyword(s):  
Second Harmonic Generation ◽  
Harmonic Generation ◽  
Second Harmonic ◽  
Field Enhancement ◽  
Normal Incidence ◽  
Electrical Field ◽  
Fundamental Wavelength ◽  
Reflectivity Spectra ◽  
Lift Off ◽  
Second Order Nonlinearity

Metasurfaces of gold (Au) nanoparticles on a SiO2-Si substrate were fabricated for the enhancement of second harmonic generation (SHG) using electron beam lithography and lift-off. Triangular Au nanoprisms which are non-centro-symmetric and support second-order nonlinearity were examined for SHG. The thickness of the SiO2 spacer is shown to be an effective parameter to tune for maximising SHG. Electrical field enhancement at the fundamental wavelength was shown to define the SHG intensity. Numerical modeling of light enhancement was verified by experimental measurements of SHG and reflectivity spectra at the normal incidence. At the plasmonic resonance, SHG is enhanced up to ∼3.5 × 103 times for the optimised conditions.

Two-Dimensional Label-Free Affinity Analysis of Tumor-Specific CD8 T Cells with a Biomimetic Plasmonic Sensor

ACS Sensors ◽  
2018 ◽  
Vol 3 (11) ◽  
pp. 2286-2295 ◽  
Author(s):  
Maria Soler ◽  
Xiaokang Li ◽  
Aurelian John-Herpin ◽  
Julien Schmidt ◽  
George Coukos ◽  
...  
Keyword(s):  
T Cells ◽  
Cd8 T Cells ◽  
Two Dimensional ◽  
Label Free ◽  
Plasmonic Sensor
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