scholarly journals Antibacterial Properties of Graphene-Based Nanomaterials

Nanomaterials ◽  
2019 ◽  
Vol 9 (5) ◽  
pp. 737 ◽  
Author(s):  
Parveen Kumar ◽  
Peipei Huo ◽  
Rongzhao Zhang ◽  
Bo Liu
Keyword(s):  
Pathogenic Bacteria ◽  
Antibacterial Agents ◽  
Antibacterial Properties ◽  
Chronic Illnesses ◽  
Antibacterial Materials ◽  
Wide Range ◽  
New Ideas ◽  
Efficient Alternative ◽  
Further Development ◽  
Toxicity Criteria

Bacteria mediated infections may cause various acute or chronic illnesses and antibiotic resistance in pathogenic bacteria has become a serious health problem around the world due to their excessive use or misuse. Replacement of existing antibacterial agents with a novel and efficient alternative is the immediate demand to alleviate this problem. Graphene-based materials have been exquisitely studied because of their remarkable bactericidal activity on a wide range of bacteria. Graphene-based materials provide advantages of easy preparation, renewable, unique catalytic properties, and exceptional physical properties such as a large specific surface area and mechanical strength. However, several queries related to the mechanism of action, significance of size and composition toward bacterial activity, toxicity criteria, and other issues are needed to be addressed. This review summarizes the recent efforts that have been made so far toward the development of graphene-based antibacterial materials to face current challenges to combat against the bacterial targets. This review describes the inherent antibacterial activity of graphene-family and recent advances that have been made on graphene-based antibacterial materials covering the functionalization with silver nanoparticles, other metal ions/oxides nanoparticles, polymers, antibiotics, and enzymes along with their multicomponent functionalization. Furthermore, the review describes the biosafety of the graphene-based antibacterial materials. It is hoped that this review will provide valuable current insight and excite new ideas for the further development of safe and efficient graphene-based antibacterial materials.

Progress in the Preparation of Silver Nanometer Antibacterial Material

2020 ◽  
Vol 996 ◽  
pp. 76-81
Author(s):  
Ben Jiao Li ◽  
Song Li ◽  
Bin Rong Ma ◽  
Yong Jing ◽  
Zhe Ming Zhang ◽  
...  
Keyword(s):  
Chemical Method ◽  
Antibacterial Agents ◽  
Antibacterial Properties ◽  
Physical Method ◽  
Biological Method ◽  
Preparation Methods ◽  
Antibacterial Materials ◽  
Development And Utilization ◽  
Antibacterial Material ◽  
Further Development

Silver inorganic antibacterial agents have been widely used inbiotechnology, bioengineering science, electronics, optics and water treatment because of their strong bactericidal ability, high safety and durable antibacterial properties. In this paper, the preparation methods of silver nanoparticles are reviewed, including physical method, chemical method and biological method, in order to provide a reference for the further development and utilization of silver nano-antibacterial materials.

scholarly journals N-acetylneuraminic acid specific lectin and antibacterial activity from the red alga Gracilaria canaliculata Sonder

Algologia ◽  
2021 ◽  
Vol 31 (2) ◽  
pp. 126-140
Author(s):  
Le Dinh Hung ◽  
◽  
Vo Thi Dieu Trang ◽  
Keyword(s):  
Vibrio Parahaemolyticus ◽  
Pathogenic Bacteria ◽  
Antibacterial Agents ◽  
Aqueous Ethanol ◽  
Divalent Cations ◽  
Red Alga ◽  
Acetylneuraminic Acid ◽  
High Affinity ◽  
Sds Page ◽  
Wide Range

A new lectin from the marine red alga Gracilaria canaliculata (GCL) was isolated by a combination of aqueous ethanol extraction, ethanol precipitation, ion exchange and filtration chromatography. Lectin gave a single band with molecular mass of 22,000 Da in both non-reducing and reducing SDS-PAGE conditions, indicating that GCL is a monomeric protein. The hemagglutination activities of GCL were stable over a wide range of pH from 3 to 10, temperature up 60 oC and not affected by either the presence of EDTA or addition of divalent cations. Lectin GCL had high affinity for N-acetylneuraminic acid through interacting with the acetamido group at equatorial C2 position of these sugar residues, suggesting that GCL is specific for N-acetylneuraminic acid. Furthermore, GCL inhibited the growth of human and shrimp pathogenic bacteria, Staphylococcus aureus and Vibrio alginolyticus, although it did not affect the growth of Escherichia coli, Enterobacter cloace, Vibrio parahaemolyticus and V. harveyi. The red alga G. canaliculata may promise to be a source of valuable lectins for application as antibacterial agents.

scholarly journals Antimicrobial Activity of Se-Nanoparticles from Bacterial Biotransformation

Fermentation ◽  
2021 ◽  
Vol 7 (3) ◽  
pp. 130
Author(s):  
Meyli Claudia Escobar-Ramírez ◽  
Araceli Castañeda-Ovando ◽  
Emmanuel Pérez-Escalante ◽  
Gabriela Mariana Rodríguez-Serrano ◽  
Esther Ramírez-Moreno ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Pathogenic Bacteria ◽  
Negative Charge ◽  
Antibacterial Properties ◽  
Growth Conditions ◽  
Bacteria Growth ◽  
Microbial Inhibition ◽  
Wide Range ◽  
Main Factors ◽  
Biological Methods

Selenium nanoparticles (SeNPs) are gaining importance in the food and medical fields due to their antibacterial properties. The microbial inhibition of these kinds of particles has been tested in a wide range of Gram (+) and Gram (−) pathogenic bacteria. When SeNPs are synthesized by biological methods, they are called biogenic SeNPs, which have a negative charge caused by their interaction between surface and capping layer (bioorganic material), producing their high stability. This review is focused on SeNPs synthesis by bacteria and summarizes the main factors that influence their main characteristics: shape, size and surface charge, considering the bacteria growth conditions for their synthesis. The different mechanisms of antimicrobial activity are revised, and this review describes several biosynthesis hypotheses that have been proposed due to the fact that the biological mechanism of SeNP synthesis is not fully known.

Photosensitive properties, synergistic antibacterial abilities of intelligent response-type self-assembled nanoparticle TiO2@V2O5

2020 ◽  
Vol 35 (6) ◽  
pp. 696-708
Author(s):  
Yanan Liu ◽  
Jiawei Liu ◽  
Xiaoping Guo ◽  
Ange Lin ◽  
Yayu Wen ◽  
...  
Keyword(s):  
Hydroxyl Radicals ◽  
Pollution Control ◽  
Self Assembly ◽  
Pathogenic Bacteria ◽  
Antibacterial Properties ◽  
Response Type ◽  
E Coli ◽  
Antibacterial Materials ◽  
Related Cell ◽  
And Staphylococcus Aureus

Representative pathogenic bacteria such as Escherichia coli ( E. coli) and Staphylococcus aureus ( S. aureus) are widespread in nature and pose a threat to human health. To control the propagation of these pathogens from the source, the key is to design broad-spectrum antibacterial materials to reduce the serious damage of pathogenic bacteria. At present, more and more nanoparticles are widely researched and applied due to their multi-pathway antibacterial properties, such as regulating physiology, biochemistry and physical chemistry. In this work, we synthesized a uniformly dispersed and stable spherical nanoparticle (TiO2@V2O5) synthesized by self-assembly of tianium dioxide and vanadium pentoxide. Based on its excellent photosensitive properties, TiO2@V2O5 nanoparticles have showed excellent antibacterial properties under the light irradiation due to the production of hydroxyl radicals in antibacterial and mechanism tests. In addtion, related cell and plant experiments have showed that TiO2@V2O5 nanoparticles are excellent biocompatible materials, it could be widely used in environmental pollution control, limiting the serious damage caused by pathogens.

Design and Discovery of New Antibacterial Agents: Advances, Perspectives, Challenges

2019 ◽  
Vol 25 (38) ◽  
pp. 4972-5006 ◽  
Author(s):  
Josef Jampilek
Keyword(s):  
Small Molecules ◽  
Bacterial Infections ◽  
Antibacterial Agents ◽  
Bacterial Resistance ◽  
Antibacterial Properties ◽  
Molecular Scaffolds ◽  
Antibacterial Compounds ◽  
Drug Classes ◽  
First Choice ◽  
Wide Range

Background: Emerging resistance of bacterial pathogens to clinically used drugs, including not only first-choice but also second- and third-choice drugs, is alarming, but since the 1990s only a modest number of new, first in class, drugs for systemic administration have been marketed for the treatment of bacterial infections. Objective: This article provides a review of recently reported new antibacterial chemotherapeutics approved for clinical practice, antibacterial chemotherapeutics in clinical trials and antibacterial agents under development. Discussion: Antibacterial agents include new antibacterial compounds of used drug classes and new antibacterial agents with a novel mode of action. In addition, particular attention is given to agents decreasing bacterial resistance, i.e. to compounds that do not have significant intrinsic bacteriostatic or bactericidal activity, but in combination with antibacterial drugs are able to restore the effect of these drugs or demonstrate synergistic antibacterial properties together with the drugs. Conclusion: This review is specifically focused on small molecules rather than on peptides and discusses a wide range of various molecular scaffolds.

scholarly journals Microbiological analysis for drug resistant pathogenic microorganisms with determination of the antibacterial properties found in Fragaria x ananassa (strawberry) samples

2017 ◽  
Vol 6 (1) ◽  
pp. 16-19
Author(s):  
Nazneen Piangka ◽  
Tasnia Ahmed ◽  
Mrityunjoy Acharjee
Keyword(s):  
Pathogenic Bacteria ◽  
Antibacterial Properties ◽  
Microbiological Analysis ◽  
Drug Resistant ◽  
E Coli ◽  
Three Samples ◽  
Wide Range ◽  
Two Samples ◽  
Health Related

Strawberry is a popular fruit item consumed by people all over the world for its exceptional flavor and aroma. This fruit is being used to prepare a wide range of food items. Strawberries when consumed by people without undergoing any processing, the condition may not be good enough. People may get sick after consuming raw strawberries. Our current study identified several pathogenic bacteria which are very known in causing health related problems. E. coli was found in one sample (1.0×102 cfu/g), Staphylococcus aureus was commonly present in all of the five samples (up to 1.2×106 cfu/g), Klebsiella spp. was found to be present in two samples (within 1.0×103 cfu/g) and Pseudomonas spp. was present in three samples (8.2×104 cfu/g), respectively. All isolated bacteria showed some degree of drug resistant traits against some commonly used antibiotics. The most important and promising part of the study was to successfully find the antimicrobial activity of strawberries against seven types of pathogenic bacteriaStamford Journal of Microbiology, Vol.6(1) 2016: 16-19

scholarly journals A Feasible Method Applied to One-Bath Process of Wool/Acrylic Blended Fabrics with Novel Heterocyclic Reactive Dyes and Application Properties of Dyed Textiles

Polymers ◽  
2020 ◽  
Vol 12 (2) ◽  
pp. 285
Author(s):  
Meihui Wang ◽  
Xianfeng Wang ◽  
Chong Guo ◽  
Tao Zhao ◽  
Wenyao Li
Keyword(s):  
Ph Value ◽  
Antibacterial Properties ◽  
Reactive Dyes ◽  
Chloride Salt ◽  
Factors Affecting ◽  
Functional Textiles ◽  
Wide Range ◽  
One Bath Dyeing ◽  
Color Depth ◽  
Further Development

Reactive dyes containing cationic groups have great potentiality as novel dyes, which can be applicable to one-bath dyeing of wool/acrylic blended fabrics. In this work, four novel heterocyclic reactive dyes containing cationic groups were designed by using m-aminophenyltrimethylammonium salt or N-(2-aminoethyl) pyridinium chloride salt as cationic groups, N, N-diethyl-1,3-benzenediamine as a coupling component, 2-amino-6-methoxybenzothiazole, 2-aminobenzothiazole or 3-amino-5-nitrobenzoisothiazole as diazo components. These dyes based on benzothiazole derivative chromophores not only showed beautiful color, including blue-green and fuchsia, but also had larger tinctorial strength with a high molar extinction coefficient, further reducing the dosage of dyes to achieve same color depth. Factors affecting the dyeability on fabrics, such as pH value, dyeing temperature and dye concentration were discussed. Excellent dyeing behavior, levelling properties and good fastness on wool/acrylic blended fabric were obtained. What’ more, excellent anti-ultraviolet and antibacterial properties were obtained for textiles with these dyes. The application of these dyes with large molar extinction coefficients presents a wide range of possibilities for the further development of cleaner production and eco-friendly dyeing, even functional textiles.

Antibiofilm Action of ZnO, SnO2 and CeO2 Nanoparticles Towards Grampositive Biofilm Forming Pathogenic Bacteria

2020 ◽  
Vol 14 (3) ◽  
pp. 239-249 ◽  
Author(s):  
Fazlurrahman Khan ◽  
Jang-Won Lee ◽  
Dung N.T. Pham ◽  
Mohammad M. Khan ◽  
Seul-Ki Park ◽  
...  
Keyword(s):  
Biofilm Formation ◽  
Metallic Nanoparticles ◽  
Pathogenic Bacteria ◽  
Antibacterial Properties ◽  
Antibiofilm Activity ◽  
Amyloid Protein ◽  
Human Pathogens ◽  
Zno Nps ◽  
Wide Range

Background: The ability to form biofilm and produce several virulence factors has caused numerous human pathogens to become tremendously resistant towards traditional antibiotic treatments, thus, new alternative strategies are urgently in demand. One of the strategies that have recently been developed involves the application of metallic Nanoparticles (NPs). Up to the present, promising results in terms of antimicrobial and antibiofilm activities have been observed in a wide range of metal NPs. Methods: The present study has selected three metal oxides such as ZnO, SnO2 and CeO2 NPs to comparatively investigate their antibiofilm and antibacterial properties against two Gram-positive human pathogens, which are Listeria monocytogenes and Staphylococcus aureus. Result: The anti-biofilm activities of ZnO, SnO2 and CeO2 NPs against S. aureus and L. monocytogenes were assayed by crystal violet staining and confirmed by microscopic visualization using SEM. The synthesis of amyloid protein by S. aureus and exopolysaccharide by L. monocytogenes in the presence of ZnO, SnO2 and CeO2 NPs was evaluated by Congo red assay. Conclusion: Overall, these results indicated that ZnO, SnO2 and CeO2 NPs can be considered as potential agents for treating the infections caused by L. monocytogenes and S. aureus, especially those associated with biofilm formation. Based on the present study, further studies are required to understand their mechanisms at both phenotypic and molecular levels, as well as their in vivo cytotoxicity, thereby enabling the applications of these metal oxide NPs in biomedical fields and food industry. Discussion: Results have shown that ZnO, SnO2 and CeO2 NPs effectively inhibited biofilm formation of both L. monocytogenes and S. aureus. The microscopic analysis also confirmed the antibiofilm activity of these NPs. It was also found that only ZnO NPs inhibited cell growth as well as the production of amyloid protein in S. aureus.

Application of TEM to Deformation, Wear, and Fracture of Ceramics

1974 ◽  
Vol 32 ◽  
pp. 472-473
Author(s):  
B. J. Hockey
Keyword(s):  
Wear Resistance ◽  
High Temperature ◽  
Mechanical Behavior ◽  
Brittle Materials ◽  
High Temperature Strength ◽  
Wide Range ◽  
Corrosive Environments ◽  
Further Development

Ceramics, such as Al2O3 and SiC have numerous current and potential uses in applications where high temperature strength, hardness, and wear resistance are required often in corrosive environments. These materials are, however, highly anisotropic and brittle, so that their mechanical behavior is often unpredictable. The further development of these materials will require a better understanding of the basic mechanisms controlling deformation, wear, and fracture.The purpose of this talk is to describe applications of TEM to the study of the deformation, wear, and fracture of Al2O3. Similar studies are currently being conducted on SiC and the techniques involved should be applicable to a wide range of hard, brittle materials.

Discovery of Antibacterial Agents Inhibiting the Energy-Coupling Factor (ECF) Transporters by Structure-Based Virtual Screening

2020 ◽  
Author(s):  
Eleonora Diamanti ◽  
Inda Setyawati ◽  
Spyridon Bousis ◽  
leticia mojas ◽  
lotteke Swier ◽  
...  
Keyword(s):  
Virtual Screening ◽  
Antibacterial Agents ◽  
Antimicrobial Agents ◽  
Energy Coupling ◽  
Coupling Factor ◽  
Design Synthesis ◽  
Screening Design ◽  
Starting Point ◽  
Wide Range ◽  
Vitamin Uptake

Here, we report on the virtual screening, design, synthesis and structure–activity relationships (SARs) of the first class of selective, antibacterial agents against the energy-coupling factor (ECF) transporters. The ECF transporters are a family of transmembrane proteins involved in the uptake of vitamins in a wide range of bacteria. Inhibition of the activity of these proteins could reduce the viability of pathogens that depend on vitamin uptake. Because of their central role in the metabolism of bacteria and their absence in humans, ECF transporters are novel potential antimicrobial targets to tackle infection. The hit compound’s metabolic and plasma stability, the potency (20, MIC Streptococcus pneumoniae = 2 µg/mL), the absence of cytotoxicity and a lack of resistance development under the conditions tested here suggest that this scaffold may represent a promising starting point for the development of novel antimicrobial agents with an unprecedented mechanism of action.<br>

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