scholarly journals Twice as Nice: The Duff Formylation of Umbelliferone Revised

Molecules ◽  
2021 ◽  
Vol 26 (24) ◽  
pp. 7482
Author(s):  
Vladislav V. Skarga ◽  
Vadim V. Negrebetsky ◽  
Yuri I. Baukov ◽  
Mikhail V. Malakhov
Keyword(s):  
Organic Solvents ◽  
Prospective Studies ◽  
Complete Resolution ◽  
Literature Analysis ◽  
Reaction Conditions ◽  
Pharmacological Activities ◽  
Extraction And Purification ◽  
Biological And Pharmacological Activities

More efficient and preferably more convenient and greener synthetic solutions in coumarin scaffold functionalization are in steady demand. The Duff ortho-formylation of unsubstituted umbelliferone was revised in this study. The reaction conditions were optimized based upon data from the literature analysis and resulted in unexpectedly rapid ortho-formylation of umbelliferone, yielding a mixture of ortho-formyl position isomers. Thorough studies on the separation of ortho-formylated umbelliferones using chromatographic and recrystallization methods as well as the evaluation of their solubility in common organic solvents led to complete resolution of 8-formyl- and 6-formylumbelliferones. The precise protocol for simultaneous preparation, extraction, and purification of 8-formyl- and 6-formylumbelliferones is provided, and the prospective studies of biological and pharmacological activities of these compounds are synopsized.

scholarly journals The Preparation and Structure Analysis Methods of Natural Polysaccharides of Plants and Fungi: A Review of Recent Development

Molecules ◽  
2019 ◽  
Vol 24 (17) ◽  
pp. 3122 ◽  
Author(s):  
Yan Ren ◽  
Yueping Bai ◽  
Zhidan Zhang ◽  
Wenlong Cai ◽  
Antonio Del Rio Flores
Keyword(s):  
Structural Analysis ◽  
Structure Analysis ◽  
Functional Foods ◽  
Therapeutic Agents ◽  
Pharmacological Activities ◽  
Structure Activity ◽  
Extraction And Purification ◽  
Extraction Separation ◽  
Recent Developments ◽  
Biological And Pharmacological Activities

Polysaccharides are ubiquitous biomolecules found in nature that contain various biological and pharmacological activities that are employed in functional foods and therapeutic agents. Natural polysaccharides are obtained mainly by extraction and purification, which may serve as reliable procedures to enhance the quality and the yield of polysaccharide products. Moreover, structural analysis of polysaccharides proves to be promising and crucial for elucidating structure–activity relationships. Therefore, this report summarizes the recent developments and applications in extraction, separation, purification, and structural analysis of polysaccharides of plants and fungi.

scholarly journals Synthesis and Biological Activities of Some Pyrimidine Derivatives: A Review

2020 ◽  
Vol 36 (6) ◽  
pp. 1001-1015
Author(s):  
Nadia Ali Ahmed Elkanzi
Keyword(s):  
Nitrogen Atom ◽  
Medicinal Chemistry ◽  
Biological Activities ◽  
Heterocyclic Ring ◽  
Ring System ◽  
Pyrimidine Derivatives ◽  
Pharmacological Activities ◽  
Cardiovascular Agents ◽  
Anti Hiv ◽  
Biological And Pharmacological Activities

Nitrogen containing synthetically and biologically important heterocyclic ring system namely pyrimidine possess both biological and pharmacological activities, and defend as aromatic six heterocyclic with 1and 3 nitrogen atom in ring. Preparation of pyrimidine via different methods offer its importance in fields of medicinal chemistry and Chemistry. Pyrimidines and their derivatives act as anti-inflammatory, anti-malaria, anti-tumor, cardiovascular agents, anti-neoplastic, anti-tubercular, anti- HIV, diuretic ,anti-viral, anti-microbial, ,analgesic .This review give light up on biological and pharmacological activities of pyrimidine nucleus.

Green emissive water dispersible silicon quantum dots for fluorescent and colorimetric dual mode sensing of curcumin

2021 ◽  
Author(s):  
Congjie Pan ◽  
Qiaoqiao Wen ◽  
Longfei Ma ◽  
Xuezhen Qin ◽  
Suxiang Feng
Keyword(s):  
Quantum Dots ◽  
Active Ingredient ◽  
Curcuma Longa ◽  
Dual Mode ◽  
Pharmacological Activities ◽  
Silicon Quantum Dots ◽  
Water Dispersible ◽  
Biological And Pharmacological Activities

Curcumin, an active ingredient of Curcuma longa, which possesses good biological and pharmacological activities, is effective in treating of many diseases. Developing simple and sensitive methods for detection of curcumin...

scholarly journals Naturally Occurring Flavanones: An Overview

2008 ◽  
Vol 3 (8) ◽  
pp. 1934578X0800300 ◽  
Author(s):  
Goutam Brahmachari
Keyword(s):  
Present Review ◽  
Pharmacological Activities ◽  
Structural Pattern ◽  
Naturally Occurring ◽  
Plant Families ◽  
Biological And Pharmacological Activities

Flavanones are one of the most interesting naturally occurring flavonoids in view of their structural pattern as well as biological and pharmacological potentials. The present review deals with natural flavanones reported from 1998 to mid 2007, along with their biological and pharmacological activities. The review includes more than 160 new naturally occurring flavanones from 135 references. The reported flavonoids belong to thirty-six plant families.

Influence of organic solvents in the extraction and purification of torularhodin from Sporobolomyces ruberrimus

2020 ◽  
Author(s):  
Karen Yuri Feitosa Kanno ◽  
Susan Grace Karp ◽  
Cristine Rodrigues ◽  
Valcineide Oliveira de Andrade Tanobe ◽  
Carlos Ricardo Soccol ◽  
...  
Keyword(s):  
Organic Solvents ◽  
Extraction And Purification
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