scholarly journals Development, Validation and Application of an ICP-SFMS Method for the Determination of Metals in Protein Powder Samples, Sourced in Ireland, with Risk Assessment for Irish Consumers

Molecules ◽  
2021 ◽  
Vol 26 (14) ◽  
pp. 4347
Author(s):  
Gavin Ring ◽  
Aisling Sheehan ◽  
Mary Lehane ◽  
Ambrose Furey
Keyword(s):  
Risk Assessment ◽  
Inductively Coupled Plasma ◽  
Human Health Risk ◽  
Potentially Toxic Elements ◽  
Health Impacts ◽  
Field Mass ◽  
Inductively Coupled ◽  
Powder Samples ◽  
Ich Guideline

A method has been developed, optimised and validated to analyse protein powder supplements on an inductively coupled plasma-sector field mass spectrometer (ICP-SFMS), with reference to ICH Guideline Q2 Validation of Analytical Procedures: Text and Methodology. This method was used in the assessment of twenty-one (n = 21) elements (Al, Au, Ba, Be, Bi, Cd, Co, Cr, Cu, Fe, Hg, Li, Mg, Mn, Mo, Pb, Pt, Sn, Ti, Tl, V) to evaluate the safety of thirty-six (n = 36) protein powder samples that were commercially available in the Irish marketplace in 2016/2017. Using the determined concentrations of elements in samples (µg·kg−1), a human health risk assessment was carried out to evaluate the potential carcinogenic and other risks to consumers of these products. While the concentrations of potentially toxic elements were found to be at acceptable levels, the results suggest that excessive and prolonged use of some of these products may place consumers at a slightly elevated risk for developing cancer or other negative health impacts throughout their lifetimes. Thus, the excessive use of these products is to be cautioned, and consumers are encouraged to follow manufacturer serving recommendations.

scholarly journals Determination of trace elements in human milk by inductively coupled plasma sector field mass spectrometry (ICP-SFMS)

2000 ◽  
Vol 15 (4) ◽  
pp. 335-340 ◽  
Author(s):  
Thomas Prohaska ◽  
Gunda Köllensperger ◽  
Michael Krachler ◽  
Kristof De Winne ◽  
Gerhard Stingeder ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Trace Elements ◽  
Human Milk ◽  
Inductively Coupled Plasma ◽  
Field Mass ◽  
Inductively Coupled ◽  
Sector Field Mass Spectrometry

scholarly journals A Review of Metal Levels in Urban Dust, Their Methods of Determination, and Risk Assessment

Atmosphere ◽  
2021 ◽  
Vol 12 (7) ◽  
pp. 891
Author(s):  
Chikumbusko Chiziwa Kaonga ◽  
Ishmael Bobby Mphangwe Kosamu ◽  
Wells Robert Utembe
Keyword(s):  
Heavy Metals ◽  
Risk Assessment ◽  
Inductively Coupled Plasma ◽  
Urban Dust ◽  
Risk Levels ◽  
Inductively Coupled ◽  
Icp Ms ◽  
Metal Levels ◽  
Plasma Mass Spectrometry

This review gives insights into the levels of metals in urban dust, their determination methods, and risk assessment. Urban dust harbors a number of pollutants, including heavy metals. There are various methods used for the sampling of urban dust for heavy-metal analysis and source-apportionment purposes, with the predominant one being the use of plastic sampling materials to avoid prior contamination. There are also various methods for the determination of metals, which include: atomic absorption spectroscopy (AAS) and inductively coupled plasma-mass spectrometry (ICP-MS), among others. Studies have shown that pollutants in urban dust are mainly derived from industrial activities and coal combustion, whereas traffic emissions are also an important, but not a predominant source of pollution. The varying particle-size distribution of urban dust and its large surface area makes it easier for the deposition and transport of heavy metals. Risk-assessment studies have shown that metals in urban dust could cause such problems as human pulmonary toxicity and reduction of invertebrate populations. The risk levels seem to be higher in children than adults, as some studies have shown. It is therefore important that studies on metals in urban dust should always incorporate risk assessment as one of the main issues.

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