scholarly journals Chemical Structure and Biological Activities of Secondary Metabolites from Salicornia europaea L.

Molecules ◽  
2021 ◽  
Vol 26 (8) ◽  
pp. 2252
Author(s):  
Sojeong Kim ◽  
Eun-Young Lee ◽  
Prima F. Hillman ◽  
Jaeyoung Ko ◽  
Inho Yang ◽  
...  
Keyword(s):  
Secondary Metabolites ◽  
Traditional Medicine ◽  
Salt Marshes ◽  
Chemical Structure ◽  
Biological Activities ◽  
Salt Tolerant ◽  
Salicornia Europaea ◽  
Tolerant Plant ◽  
Therapeutic Properties ◽  
Anti Inflammatory

Salicornia europaea L. is a halophyte that grows in salt marshes and muddy seashores, which is widely used both as traditional medicine and as an edible vegetable. This salt-tolerant plant is a source of diverse secondary metabolites with several therapeutic properties, including antioxidant, antidiabetic, cytotoxic, anti-inflammatory, and anti-obesity effects. Therefore, this review summarizes the chemical structure and biological activities of secondary metabolites isolated from Salicornia europaea L.

scholarly journals Piper Species: A Comprehensive Review on Their Phytochemistry, Biological Activities and Applications

Molecules ◽  
2019 ◽  
Vol 24 (7) ◽  
pp. 1364 ◽  
Author(s):  
Bahare Salehi ◽  
Zainul Amiruddin Zakaria ◽  
Rabin Gyawali ◽  
Salam A. Ibrahim ◽  
Jovana Rajkovic ◽  
...  
Keyword(s):  
Secondary Metabolites ◽  
Essential Oils ◽  
Traditional Medicine ◽  
Biological Activities ◽  
Biological Effects ◽  
Chemical Constituents ◽  
Food Preservation ◽  
Piper Nigrum ◽  
Piper Betle ◽  
Anti Inflammatory

Piper species are aromatic plants used as spices in the kitchen, but their secondary metabolites have also shown biological effects on human health. These plants are rich in essential oils, which can be found in their fruits, seeds, leaves, branches, roots and stems. Some Piper species have simple chemical profiles, while others, such as Piper nigrum, Piper betle, and Piper auritum, contain very diverse suites of secondary metabolites. In traditional medicine, Piper species have been used worldwide to treat several diseases such as urological problems, skin, liver and stomach ailments, for wound healing, and as antipyretic and anti-inflammatory agents. In addition, Piper species could be used as natural antioxidants and antimicrobial agents in food preservation. The phytochemicals and essential oils of Piper species have shown strong antioxidant activity, in comparison with synthetic antioxidants, and demonstrated antibacterial and antifungal activities against human pathogens. Moreover, Piper species possess therapeutic and preventive potential against several chronic disorders. Among the functional properties of Piper plants/extracts/active components the antiproliferative, anti-inflammatory, and neuropharmacological activities of the extracts and extract-derived bioactive constituents are thought to be key effects for the protection against chronic conditions, based on preclinical in vitro and in vivo studies, besides clinical studies. Habitats and cultivation of Piper species are also covered in this review. In this current work, available literature of chemical constituents of the essential oils Piper plants, their use in traditional medicine, their applications as a food preservative, their antiparasitic activities and other important biological activities are reviewed.

scholarly journals Chemical Constituents and Biological Activity Profiles on Pleione (Orchidaceae)

Molecules ◽  
2019 ◽  
Vol 24 (17) ◽  
pp. 3195 ◽  
Author(s):  
Xiao-Qian Wu ◽  
Wei Li ◽  
Jing-Xin Chen ◽  
Jun-Wen Zhai ◽  
Hui-You Xu ◽  
...  
Keyword(s):  
Biological Activity ◽  
Structural Analysis ◽  
Secondary Metabolites ◽  
Traditional Medicine ◽  
Significant Role ◽  
Biological Activities ◽  
Chemical Constituents ◽  
Chemical Compounds ◽  
Southern Asia ◽  
Anti Inflammatory

Pleione (Orchidaceae) is not only famous for the ornamental value in Europe because of its special color, but also endemic in Southern Asia for its use in traditional medicine. A great deal of research about its secondary metabolites and biological activities has been done on only three of 30 species of Pleione. Up to now, 183 chemical compounds, such as phenanthrenes, bibenzyls, glucosyloxybenzyl succinate derivatives, flavonoids, lignans, terpenoids, etc., have been obtained from Pleione. These compounds have been demonstrated to play a significant role in anti-tumor, anti-neurodegenerative and anti-inflammatory biological activities and improve immunity. In order to further develop the drugs and utilize the plants, the chemical structural analysis and biological activities of Pleione are summarized in this review.

scholarly journals Pharmacological Insights into Halophyte Bioactive Extract Action on Anti-Inflammatory, Pain Relief and Antibiotics-Type Mechanisms

Molecules ◽  
2021 ◽  
Vol 26 (11) ◽  
pp. 3140
Author(s):  
Rocco Giordano ◽  
Zeinab Saii ◽  
Malthe Fredsgaard ◽  
Laura Sini Sofia Hulkko ◽  
Thomas Bouet Guldbæk Poulsen ◽  
...  
Keyword(s):  
Pain Relief ◽  
Bioactive Compounds ◽  
Biomedical Applications ◽  
Medicinal Products ◽  
Salt Tolerant ◽  
Salicornia Europaea ◽  
Pharmacological Activities ◽  
Sustainable Resources ◽  
Anti Inflammatory ◽  
Significant Attention

The pharmacological activities in bioactive plant extracts play an increasing role in sustainable resources for valorization and biomedical applications. Bioactive phytochemicals, including natural compounds, secondary metabolites and their derivatives, have attracted significant attention for use in both medicinal products and cosmetic products. Our review highlights the pharmacological mode-of-action and current biomedical applications of key bioactive compounds applied as anti-inflammatory, bactericidal with antibiotics effects, and pain relief purposes in controlled clinical studies or preclinical studies. In this systematic review, the availability of bioactive compounds from several salt-tolerant plant species, mainly focusing on the three promising species Aster tripolium, Crithmum maritimum and Salicornia europaea, are summarized and discussed. All three of them have been widely used in natural folk medicines and are now in the focus for future nutraceutical and pharmacological applications.

scholarly journals PHARMACOLOGICAL IMPORTANCE OF MORINGA CONCANENSIS NIMMO LEAF: AN OVERVIEW

2019 ◽  
pp. 27-31
Author(s):  
AMERENDRA SINGH ◽  
JAI NARAYAN MISHRA ◽  
SANTOSH KUMAR SINGH
Keyword(s):  
Traditional Medicine ◽  
Biological Activities ◽  
Medicinal Uses ◽  
Plant Life ◽  
Crude Extracts ◽  
The Future ◽  
Anti Inflammatory ◽  
Scientific Facts

In the current years, the use of traditional medicine is increasing and gaining popularity. The extracts of Moringa concanensis Nimmo leaves have reported many medicinal uses. In the previous few decades, a massive quantity of scientific facts concerning plants, crude extracts, and quite a number supplies from plant life as medicinal dealers has come to light. M. concanensis is a plant whose components are oftentimes used in the medicinal treatments. There are good sized anecdotal facts about the organic undertaking of M. concanensis which includes anticancerous, antibacterial, antifungal, analgesic, and anti-inflammatory type of activities. The leaves of M. concanensis had been located to contain a higher quantity of triterpenoids and flavonoids. The existing assessment includes the phytochemical, ethnopharmacological, and pharmacological reviews of M. concanensis. The future scope of the plant has been emphasized with a view to isolate bioactive moieties which should be used for multifarious biological activities.

scholarly journals Bioactivities and Future Perspectives of Chaetoglobosins

2020 ◽  
Vol 2020 ◽  
pp. 1-10 ◽  
Author(s):  
Jinhua Chen ◽  
Wenzhou Zhang ◽  
Qingfeng Guo ◽  
Weijiang Yu ◽  
Yongna Zhang ◽  
...  
Keyword(s):  
Secondary Metabolites ◽  
Large Class ◽  
Biological Activities ◽  
Mechanisms Of Action ◽  
Chaetomium Globosum ◽  
Future Perspectives ◽  
Anti Inflammatory ◽  
Anti Hiv ◽  
Fungal Secondary Metabolites

Chaetoglobosins belonging to cytochalasan alkaloids represent a large class of fungal secondary metabolites. To date, around 100 chaetoglobosins and their analogues have been isolated and identified over the years from a variety of fungi, mainly from the fungus Chaetomium globosum. Studies have found that chaetoglobosins possess a broad range of biological activities, including antitumor, antifungal, phytotoxic, fibrinolytic, antibacterial, nematicidal, anti-inflammatory, and anti-HIV activities. This review will comprehensively summarize the biological activities and mechanisms of action of nature-derived chaetoglobosins.

scholarly journals Efecto antiinflamatorio de extractos etanólicos de Morinda citrifolia L. en conejos

Tequio ◽  
2019 ◽  
Vol 2 (6) ◽  
pp. 26-34
Author(s):  
Irma Cecilia Regino Álvarez ◽  
María de la Luz Ríos Vásquez ◽  
Héctor Ulises Bernardino Hernández ◽  
Arturo Zapién Martínez
Keyword(s):  
Secondary Metabolites ◽  
Leaf Extract ◽  
Adverse Reactions ◽  
Morinda Citrifolia ◽  
San Jose ◽  
Mature Leaves ◽  
Therapeutic Properties ◽  
Anti Inflammatory ◽  
Ethanol Extracts ◽  
Inflammatory Effect

Morinda citrifolia L. has multiple therapeutic properties, particularly as an anti-inflammatory. The species has been widely studied, however, it is necessary to expand studies to document the presence of secondary metabolites and the anti-inflammatory effect of its extracts in animal models. The objective of the present paper was to identify the secondary metabolites present in the ethanol extracts of leaves and fruit of Morinda citrifolia L. collected in the community of San José Rio Manso, municipality of Lalana Choapam, Oaxaca, as well as the evaluation of its anti-inflammatory effect in rabbits. Ethanol extracts were obtained from the green and mature leaves, as well as the juice of the fruit. Green leaf extract gels were prepared and used in a completely randomized experiment in rabbits. The presence of alkaloids, leucoantacionins, amino acids, coumarins, cardiotonics, flavonoids, terpenes and tannins was identified. The 0.5% extract was more efficient at reducing the inflamed area by 55.6% compared to 28.6% of the control, 48 hours after the induction of inflammation. No signs of adverse reactions due to the use of the pharmaceutical forms evaluated were observed.

scholarly journals Overview of Phytochemical Compounds and Pharmacological Activities of Ananas Comosus L. Merr

2020 ◽  
Vol 11 (3) ◽  
pp. 4760-4766
Author(s):  
Hartati R ◽  
Suarantika F ◽  
Fidrianny I
Keyword(s):  
Traditional Medicine ◽  
Biological Activities ◽  
Scientific Work ◽  
Ananas Comosus ◽  
Pharmacological Activities ◽  
Phytochemical Compounds ◽  
Anti Inflammatory ◽  
Vitro Analysis

Ananas comosus L. Merr, known as pineapple, belongs to the Bromeliaceae family. This plant has been used as traditional medicine and continues until now in conventional herbal medicine. The pineapple was distributed in some countries such as China, India, Indonesia, Malaysia, Thailand and originated from South America. This article delved the scientific work about Ananas comosus focussing their usage as traditional medicine, chemical compounds and biological activities. All of the pieces of information were obtained from the scientific literature such as Science Direct, Google Scholar, Scopus and PubMed. Based on the literature survey,different parts of pineapple (Ananas comosus) are used in traditional medicine, used asan anti-inflammatory agent,anti-oedema, digestive disorder, antimicrobial, vermicide, and purgative. Phytochemical compounds from A. comosus have been provided, including ascorbic acid, quercetin, flavones-3-ol, flavones, and ferulic acid. The crude extracts of A. comosus have many pharmacological activities such as anti-fungal, anti-inflammatory, antioxidant, antibacterial. This discovery becomes possible due to scientific isolation and in vivo or in vitro analysis of A.comosus.

scholarly journals Assessment of Secondary Metabolites with Different Uses of Fenugreek

2021 ◽  
Author(s):  
Gulsum Yaldiz ◽  
Mahmut Camlica
Keyword(s):  
Secondary Metabolites ◽  
Biological Activities ◽  
New Drugs ◽  
Herbal Drug ◽  
Primary Metabolite ◽  
Food Industries ◽  
Golden Yellow ◽  
Therapeutic Properties ◽  
Modern Breeding ◽  
Nutraceutical Properties

Fenugreek (Trigonella foenum-graecum) is an annual medicinal plant with trifoliate leaves, a branched stem, white flowers, rooted tubers, and golden yellow seed belonging to Fabaceae family. Fenugreek is used in different industries such as pharmaceutical, nutraceutical and food industries as an ancient crop plant. Fenugreek is grown as a medicinal herb in many countries and has antioxidant, hypoglycemic, hypercholesterolemia, stomach protective, chemopreventive, laxative and appetite stimulating properties. In recent years, many important studies have been conducted on the biological activities and therapeutic properties of fenugreek mainly secondary metabolites such as alkaloids, flavonoids, steroids and saponins. These compounds are used for multipurpose uses in different industries and also appreciated by scientists. Based on these several health usefulness as discussed in review, fenugreek might be a good candidate for a herbal drug and used for preparation of new drugs. In this review, secondary metabolites used in different industries of fenugreek will be discussed and general benefits of them will be expressed within the all significant aspect of fenugreek as clearly. This review also highlights the traditional uses and nutraceutical properties (antioxidant activity, antibacterial, antifungal, anticancer hypoglemic effects and anti-inflammatory and immunological activity) of fenugreek. These uses and effect properties of fenugreek have been discussed and researchable areas were implied to depending on the previous studies. In the future, studies on fenugreek are needed some important applications to increasing the popularity of fenugreek. In this context, researchers should be focused on secondary and primary metabolite studies in fenugreek seeds and leaves. In addition to these, fenugreek germplasm should be collected and subjected to intensive selection via modern breeding programs and new fenugreek genotypes with desired properties should be obtained.

scholarly journals Eccentric Connectivity Index of t-Polyacenic Nanotubes

2019 ◽  
Vol 2019 ◽  
pp. 1-9 ◽  
Author(s):  
Jia-Bao Liu ◽  
Hani Shaker ◽  
Imran Nadeem ◽  
Mohammad Reza Farahani
Keyword(s):  
Chemical Compound ◽  
Chemical Structure ◽  
Biological Activities ◽  
Connectivity Index ◽  
Infinite Class ◽  
Eccentric Connectivity Index ◽  
Anti Inflammatory ◽  
High Degree ◽  
Structure Descriptor

The eccentric connectivity index ECI is a chemical structure descriptor that is currently being used for the modeling of biological activities of a chemical compound. This index has been proved to provide a high degree of predictability as compared to some other well-known indices in case of anticonvulsant, anti-inflammatory, and diuretic activities. The ECI of an infinite class of 1-polyacenic (phenylenic) nanotubes has been recently studied. In this article, we extend this study to generalized polyacenic nanotubes and find ECI of t-polyacenic nanotubes for t>1.

scholarly journals Insightful Valorization of the Biological Activities of Pani Heloch Leaves through Experimental and Computer-Aided Mechanisms

Molecules ◽  
2020 ◽  
Vol 25 (21) ◽  
pp. 5153
Author(s):  
Naureen Banu ◽  
Najmul Alam ◽  
Mohammad Nazmul Islam ◽  
Sanjida Islam ◽  
Shahenur Alam Sakib ◽  
...  
Keyword(s):  
Secondary Metabolites ◽  
Methanol Extract ◽  
Biological Activities ◽  
Biological Effects ◽  
Experimental Models ◽  
Clot Lysis ◽  
Control Group ◽  
Anti Inflammatory

Pani heloch (Antidesma montanum) is traditionally used to treat innumerable diseases and is a source of wild vegetables for the management of different pathological conditions. The present study explored the qualitative phytochemicals; quantitative phenol and flavonoid contents; in vitro antioxidant, anti-inflammatory, and thrombolytic effects; and in vivo antipyretic and analgesic properties of the methanol extract of A. montanum leaves in different experimental models. The extract exhibited secondary metabolites including alkaloids, flavonoids, flavanols, phytosterols, cholesterols, phenols, terpenoids, glycosides, fixed oils, emodines, coumarins, resins, and tannins. Besides, Pani heloch showed strong antioxidant activity (IC50 = 99.00 µg/mL), while a moderate percentage of clot lysis (31.56%) in human blood and significant anti-inflammatory activity (p < 0.001) was achieved with the standard. Moreover, the analgesic and antipyretic properties appeared to trigger a significant response (p < 0.001) relative to in the control group. Besides, an in silico study of carpusin revealed favorable protein-binding affinities. Furthermore, the absorption, distribution, metabolism, excretion, and toxicity analysis and toxicological properties of all isolated compounds adopted Lipinski’s rule of five for drug-like potential and level of toxicity. Our research unveiled that the methanol extract of A. montanum leaves exhibited secondary metabolites that are a good source for managing inflammation, pyrexia, pain, and cellular toxicity. Computational approaches and further studies are required to identify the possible mechanism which responsible for the biological effects.

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