scholarly journals Recent Advances in Electrochemiluminescence and Chemiluminescence of Metal Nanoclusters

Molecules ◽  
2020 ◽  
Vol 25 (21) ◽  
pp. 5208
Author(s):  
Shuang Han ◽  
Yuhui Zhao ◽  
Zhichao Zhang ◽  
Guobao Xu
Keyword(s):  
Electron Transfer ◽  
Analytical Methods ◽  
Signal Amplification ◽  
Intramolecular Electron Transfer ◽  
Metal Nanoclusters ◽  
Intermolecular Electron Transfer ◽  
Metal Core ◽  
Size Dependent ◽  
Good Solubility ◽  
Highly Sensitive

Metal nanoclusters (NCs), including Au, Ag, Cu, Pt, Ni and alloy NCs, have become more and more popular sensor probes with good solubility, biocompatibility, size-dependent luminescence and catalysis. The development of electrochemiluminescent (ECL) and chemiluminescent (CL) analytical methods based on various metal NCs have become research hotspots. To improve ECL and CL performances, many strategies are proposed, from metal core to ligand, from intermolecular electron transfer to intramolecular electron transfer. Combined with a variety of amplification technology, i.e., nanostructure-based enhancement and biological signal amplification, highly sensitive ECL and CL analytical methods are developed. We have summarized the research progresses since 2016. Also, we discuss the current challenges and perspectives on the development of this area.

Electrochemical Studies on the Competition Between Intramolecular Electron Transfer and Intermolecular Protonation of Nitroaryl Radical Anions in the Reductions of Apical Carboxylic Acid Substituents of 2- and 3-Nitro- 9,10-dihydro-9,10-ethanoanthracene-9-carboxylic Acids

1997 ◽  
Vol 50 (10) ◽  
pp. 999 ◽  
Author(s):  
Peter A. Lay ◽  
Robert K. Norris ◽  
Paul K. Witting
Keyword(s):  
Electron Transfer ◽  
Carboxylic Acid ◽  
Carboxylic Acids ◽  
Acid Group ◽  
Intramolecular Electron Transfer ◽  
Radical Anions ◽  
Intermolecular Electron Transfer ◽  
Electron Transfer Mechanism ◽  
Reduction Potentials ◽  
Bridgehead Position

The results obtained from variable scan rate cyclic voltammetry (c.v.) on 2-nitro- and 3-nitro-9,10- dihydro-9,10-ethanoanthracene-9-carboxylic acids [(4) and (5), respectively], combined with simulations of various c.v. responses, are consistent with reduction of a benzylic acid group being facilitated by an intramolecular electron transfer process. This intramolecular process involves a one-electron reduction of the nitroaromatic group, followed by a rapid and irreversible π*(ArNO2)•- → π*(RCO2H)•- intramolecular electron transfer to the carboxylic acid group at a benzylic bridgehead position of the acids (4) and (5). The reduction potentials of the acid groups are shifted more than 0·3 V to positive potentials at slow scan rates (20-100 mV s-1) compared with the unnitrated acid derivative (6). The reduction potentials and the relative peak currents for the reductions of the nitro and acid groups for each of compounds (4) and (5) are dependent on the concentrations of the reactants. At concentrations of substrate >1 mM, reduction of the acid moiety is increasingly dependent on complex intermolecular processes. These intermolecular processes compete with intramolecular electron transfer from the nitroaryl anion to the apical acid group at the benzylic bridgehead position. Digital simulations of the voltammetric data were confined to substrate concentrations <1 mM, and show that the intramolecular reductions of the apical carboxylic acid protons of (4) and (5) are complicated by competing intermolecular electron transfer and intermolecular self-protonations of the nitro radical anions. The value of the intramolecular electron transfer rate constant for the meta compound is an order of magnitude larger than that for the para compound, which is the opposite reactivity pattern to that generally found in the SRN1 reactions of m- and p-nitrobenzyl halides. This indicates that there is likely to be an important contribution from an intramolecular through-space electron transfer mechanism for the former reaction

Detection of Glucose in Human Serum Based on Silicon Dot Probe

2020 ◽  
Vol 16 (6) ◽  
pp. 744-752
Author(s):  
Kuan Luo ◽  
Xinyu Jiang
Keyword(s):  
Quantum Dots ◽  
Blood Glucose ◽  
Human Serum ◽  
Organic Dyes ◽  
Limit Of Detection ◽  
Fasting Blood Glucose ◽  
Glucose Biosensor ◽  
Metal Nanoclusters ◽  
Glucose Levels ◽  
Highly Sensitive

Background: Diabetes Mellitus (DM) is a major public metabolic disease that influences 366 million people in the world in 2011, and this number is predicted to rise to 552 million in 2030. DM is clinically diagnosed by a fasting blood glucose that is equal or greater than 7 mM. Therefore, the development of effective glucose biosensor has attracted extensive attention worldwide. Fluorescence- based strategies have sparked tremendous interest due to their rapid response, facile operation, and excellent sensitivity. Many fluorescent compounds have been employed for precise analysis of glucose, including quantum dots, noble metal nanoclusters, up-converting nanoparticles, organic dyes, and composite fluorescent microspheres. Silicon dot as promising quantum dots materials have received extensive attention, owing to their distinct advantages such as biocompatibility, low toxicity and high photostability. Methods: MnO2 nanosheets on the Si nanoparticles (NPs) surface serve as a quencher. Si NPs fluorescence can make a recovery by the addition of H2O2, which can reduce MnO2 to Mn2+, and the glucose can thus be monitored based on the enzymatic conversion of glucose by glucose oxidase to generate H2O2. Therefore, the glucose concentration can be derived by recording the fluorescence recovery spectra of the Si NPs. Results: This probe enabled selective detection of glucose with a linear range of 1-100 μg/mL and a limit of detection of 0.98 μg/mL. Compared with the commercial glucometer, this method showed favorable results and convincing reliability. Conclusion: We have developed a novel method based on MnO2 -nanosheet-modified Si NPs for rapid monitoring of blood glucose levels. By combining the highly sensitive H2O2/MnO2 reaction with the excellent photostability of Si NPs, a highly sensitive, selective, and cost-efficient sensing approach for glucose detection has been designed and applied to monitor glucose levels in human serum with satisfactory results.

Intramolecular Electron Transfer Mediated by a Tetrathiafulvalene Bridge in a Purely Organic Mixed-Valence System

2003 ◽  
Vol 42 (24) ◽  
pp. 2765-2768 ◽  
Author(s):  
Nicolas Gautier ◽  
Frédéric Dumur ◽  
Vega Lloveras ◽  
José Vidal-Gancedo ◽  
Jaume Veciana ◽  
...  
Keyword(s):  
Electron Transfer ◽  
Mixed Valence ◽  
Intramolecular Electron Transfer

Vapochromism induced by intermolecular electron transfer coupled with hydrogen-bond formation in zinc dithiolene complex

2020 ◽  
Vol 8 (42) ◽  
pp. 14939-14947
Author(s):  
So Yokomori ◽  
Shun Dekura ◽  
Tomoko Fujino ◽  
Mitsuaki Kawamura ◽  
Taisuke Ozaki ◽  
...  
Keyword(s):  
Hydrogen Bond ◽  
Electron Transfer ◽  
Bond Formation ◽  
Intermolecular Electron Transfer ◽  
Hydrogen Bond Formation ◽  
Complex Crystal

A novel vapochromic mechanism by intermolecular electron transfer coupled with hydrogen-bond formation was realized in a zinc dithiolene complex crystal.

A highly sensitive electrochemical microRNA-21 biosensor based on intercalating methylene blue signal amplification and a highly dispersed gold nanoparticles/graphene/polypyrrole composite

The Analyst ◽  
2021 ◽  
Vol 146 (8) ◽  
pp. 2679-2688
Author(s):  
Chammari Pothipor ◽  
Noppadol Aroonyadet ◽  
Suwussa Bamrungsap ◽  
Jaroon Jakmunee ◽  
Kontad Ounnunkad
Keyword(s):  
Methylene Blue ◽  
Gold Nanoparticles ◽  
Signal Amplification ◽  
Electrochemical Biosensor ◽  
Highly Sensitive ◽  
Highly Dispersed ◽  
Polypyrrole Composite ◽  
Amplification Strategy ◽  
Dispersed Gold ◽  
Potential Tool

An ultrasensitive electrochemical biosensor based on a gold nanoparticles/graphene/polypyrrole composite modified electrode and a signal amplification strategy employing methylene blue is developed as a potential tool for the detection of miRNA-21.

scholarly journals Metal Nanoparticle and Quantum Dot Tags for Signal Amplification in Electrochemical Immunosensors for Biomarker Detection

Chemosensors ◽  
2021 ◽  
Vol 9 (4) ◽  
pp. 85
Author(s):  
Anton Popov ◽  
Benediktas Brasiunas ◽  
Asta Kausaite-Minkstimiene ◽  
Almira Ramanaviciene
Keyword(s):  
Signal Amplification ◽  
Electrochemical Immunosensor ◽  
Metal Nanoparticle ◽  
Biomarker Detection ◽  
Analytical Instruments ◽  
Electrochemical Immunosensors ◽  
Highly Sensitive ◽  
Recent Developments ◽  
Electrochemical Signal ◽  
Detection Of Biomarkers

With the increasing importance of healthcare and clinical diagnosis, as well as the growing demand for highly sensitive analytical instruments, immunosensors have received considerable attention. In this review, electrochemical immunosensor signal amplification strategies using metal nanoparticles (MNPs) and quantum dots (Qdots) as tags are overviewed, focusing on recent developments in the ultrasensitive detection of biomarkers. MNPs and Qdots can be used separately or in combination with other nanostructures, while performing the function of nanocarriers, electroactive labels, or catalysts. Thus, different functions of MNPs and Qdots as well as recent advances in electrochemical signal amplification are discussed. Additionally, the methods most often used for antibody immobilization on nanoparticles, immunoassay formats, and electrochemical methods for indirect biomarker detection are overviewed.

scholarly journals Solvent-induced on/off switching of intramolecular electron transfer in a cyanide-bridged trigonal bipyramidal complex

2016 ◽  
Vol 45 (43) ◽  
pp. 17104-17107 ◽  
Author(s):  
Rong-Jia Wei ◽  
Ryohei Nakahara ◽  
Jamie M. Cameron ◽  
Graham N. Newton ◽  
Takuya Shiga ◽  
...  
Keyword(s):  
Electron Transfer ◽  
Spin Transition ◽  
Intramolecular Electron Transfer ◽  
Thermally Induced ◽  
Trigonal Bipyramidal ◽  
Transition Behaviour

A cyanide-bridged trigonal bipyramidal [Co3Fe2] cluster shows solvent-driven reversible on/off switching of its thermally induced electron-transfer-coupled spin transition behaviour.

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