scholarly journals Non-Chromatographic Speciation of As by HG Technique—Analysis of Samples with Different Matrices

Molecules ◽  
2020 ◽  
Vol 25 (21) ◽  
pp. 4944
Author(s):  
Maja Welna ◽  
Anna Szymczycha-Madeja ◽  
Pawel Pohl
Keyword(s):  
Hydride Generation ◽  
Sample Introduction ◽  
Detection Methods ◽  
Biological Matrices ◽  
The Past ◽  
Promising Tool ◽  
As Species ◽  
Alternative Approaches ◽  
Selective Generation ◽  
Selection Of

The applicability of the hydride generation (HG) sample introduction technique combined with different spectrochemical detection methods for non-chromatographic speciation of toxic As species, i.e., As(III), As(V), dimethylarsinate (DMA) and monomethylarsonate (MMA), in waters and other environmental, food and biological matrices is presented as a promising tool to speciate As by obviating chromatographic separation. Different non-chromatographic procedures along with speciation protocols reported in the literature over the past 20 year are summarized. Basic rules ensuring species selective generation of the corresponding hydrides are presented in detail. Common strategies and alternative approaches are highlighted. Aspects of proper sample preparation before analysis and the selection of adequate strategies for speciation purposes are emphasized.

Integrated FAHP-VIKOR model for green supplier selection in a Nickle coating SME

2020 ◽  
pp. 133-139
Author(s):  
Sanatan Ratna ◽  
B Kumar
Keyword(s):  
Staff Training ◽  
Supplier Selection ◽  
Fuzzy Ahp ◽  
Research Work ◽  
Supplier Evaluation ◽  
Green Supplier Selection ◽  
The Past ◽  
Coating Industry ◽  
Sustainability Issue ◽  
Selection Of

In the past few decades, there has been lot of focus on the issue of sustainability. This has occurred due to the growing concerns related to climate change and the growing awareness about environmental concerns. Also, the competition at global level has led to the search for the most sustainable route in the industries. The current research work deals with the selection of green supplier in a Nickle coating industry based on certain weighted green attributes. For this purpose, a hybrid tool comprising of Fuzzy AHP (Fuzzy Analytical Hierarchy) and VIKOR (VlseKriterijumska Optimizacija I Kompromisno Resenje) is used. The Fuzzy AHP is used for assigning proper weights to the selected criteria for supplier evaluation, while VIKOR is used for final supplier selection based on the weighted criteria. The three criterions for green supplier selection are, Ecological packaging, Corporate socio-environmental responsibility and Staff Training. The outcome of the integrated model may serve as a steppingstone to other SMEs in different sectors for selecting the most suitable supplier for addressing the sustainability issue.

Automated Detection of Pin Defects on Counterfeit Microelectronics

2018 ◽  
Author(s):  
Pallabi Ghosh ◽  
Domenic Forte ◽  
Damon L. Woodard ◽  
Rajat Subhra Chakraborty
Keyword(s):  
Integrated Circuits ◽  
Depth Map ◽  
Optical Microscope ◽  
Automated Detection ◽  
Detection Methods ◽  
Global Supply Chains ◽  
Subject Matter Experts ◽  
Security Breaches ◽  
The Past ◽  
Skilled Subject

Abstract Counterfeit electronics constitute a fast-growing threat to global supply chains as well as national security. With rapid globalization, the supply chain is growing more and more complex with components coming from a diverse set of suppliers. Counterfeiters are taking advantage of this complexity and replacing original parts with fake ones. Moreover, counterfeit integrated circuits (ICs) may contain circuit modifications that cause security breaches. Out of all types of counterfeit ICs, recycled and remarked ICs are the most common. Over the past few years, a plethora of counterfeit IC detection methods have been created; however, most of these methods are manual and require highly-skilled subject matter experts (SME). In this paper, an automated bent and corroded pin detection methodology using image processing is proposed to identify recycled ICs. Here, depth map of images acquired using an optical microscope are used to detect bent pins, and segmented side view pin images are used to detect corroded pins.

Evidence-based Assessment

2010 ◽  
pp. 76-98
Author(s):  
John Hunsley ◽  
Eric J. Mash
Keyword(s):  
Decision Making ◽  
Clinical Assessment ◽  
Assessment Process ◽  
Evidence Based ◽  
The Past ◽  
Specific Assessment ◽  
The Many ◽  
Selection Of ◽  
Made In

Evidence-based assessment relies on research and theory to inform the selection of constructs to be assessed for a specific assessment purpose, the methods and measures to be used in the assessment, and the manner in which the assessment process unfolds. An evidence-based approach to clinical assessment necessitates the recognition that, even when evidence-based instruments are used, the assessment process is a decision-making task in which hypotheses must be iteratively formulated and tested. In this chapter, we review (a) the progress that has been made in developing an evidence-based approach to clinical assessment in the past decade and (b) the many challenges that lie ahead if clinical assessment is to be truly evidence-based.

scholarly journals Alternative approaches to target Myc for cancer treatment

2021 ◽  
Vol 6 (1) ◽  
Author(s):  
Chen Wang ◽  
Jiawei Zhang ◽  
Jie Yin ◽  
Yichao Gan ◽  
Senlin Xu ◽  
...  
Keyword(s):  
Cancer Treatment ◽  
Small Molecules ◽  
Drug Target ◽  
The Past ◽  
Physiological Processes ◽  
Alternative Approaches ◽  
Global Transcriptome ◽  
Factor C ◽  
Signaling Modules ◽  
Druggable Targets

AbstractThe Myc proto-oncogene family consists of three members, C-MYC, MYCN, and MYCL, which encodes the transcription factor c-Myc (hereafter Myc), N-Myc, and L-Myc, respectively. Myc protein orchestrates diverse physiological processes, including cell proliferation, differentiation, survival, and apoptosis. Myc modulates about 15% of the global transcriptome, and its deregulation rewires the cellular signaling modules inside tumor cells, thereby acquiring selective advantages. The deregulation of Myc occurs in >70% of human cancers, and is related to poor prognosis; hence, hyperactivated Myc oncoprotein has been proposed as an ideal drug target for decades. Nevertheless, no specific drug is currently available to directly target Myc, mainly because of its “undruggable” properties: lack of enzymatic pocket for conventional small molecules to bind; inaccessibility for antibody due to the predominant nucleus localization of Myc. Although the topic of targeting Myc has actively been reviewed in the past decades, exciting new progresses in this field keep emerging. In this review, after a comprehensive summarization of valuable sources for potential druggable targets of Myc-driven cancer, we also peer into the promising future of utilizing macropinocytosis to deliver peptides like Omomyc or antibody agents to intracellular compartment for cancer treatment.

scholarly journals Standardizing human brain parcellations

2021 ◽  
Vol 8 (1) ◽  
Author(s):  
Ross M. Lawrence ◽  
Eric W. Bridgeford ◽  
Patrick E. Myers ◽  
Ganesh C. Arvapalli ◽  
Sandhya C. Ramachandran ◽  
...  
Keyword(s):  
Human Brain ◽  
Coordinate Space ◽  
The Past ◽  
File Storage ◽  
Statistical Inferences ◽  
Standardized Protocol ◽  
Storage Format ◽  
Labeling Scheme ◽  
Selection Of ◽  
Brain Atlases

AbstractUsing brain atlases to localize regions of interest is a requirement for making neuroscientifically valid statistical inferences. These atlases, represented in volumetric or surface coordinate spaces, can describe brain topology from a variety of perspectives. Although many human brain atlases have circulated the field over the past fifty years, limited effort has been devoted to their standardization. Standardization can facilitate consistency and transparency with respect to orientation, resolution, labeling scheme, file storage format, and coordinate space designation. Our group has worked to consolidate an extensive selection of popular human brain atlases into a single, curated, open-source library, where they are stored following a standardized protocol with accompanying metadata, which can serve as the basis for future atlases. The repository containing the atlases, the specification, as well as relevant transformation functions is available in the neuroparc OSF registered repository or https://github.com/neurodata/neuroparc.

Cross Double Point Discharge as Enhanced Excitation Source for Highly Sensitive Determination of Arsenic, Mercury and Lead by Optical Emission Spectrometry

2021 ◽  
Author(s):  
Lin He ◽  
Peixia Li ◽  
Kai Li ◽  
Tao Lin ◽  
Jin Luo ◽  
...  
Keyword(s):  
Double Point ◽  
Hydride Generation ◽  
Optical Emission ◽  
Sample Introduction ◽  
Excitation Source ◽  
Emission Spectrometry ◽  
Highly Sensitive ◽  
Point Discharge ◽  
Sensitive Determination

A new cross double point discharge (CrossPD) microplasma was designed as an excitation source to construct a miniaturized optical emission spectrometer with hydride generation (HG) for sample introduction. The CrossPD...

scholarly journals A Students’ Preferences-Based Approach to Select Methods for Detecting and Handling Free-Riding

2021 ◽  
pp. 027347532199210
Author(s):  
Else-Marie van den Herik ◽  
Tim M. Benning
Keyword(s):  
International Students ◽  
Evaluation System ◽  
Online Survey ◽  
Free Riding ◽  
Detection Methods ◽  
Chi Squared ◽  
Ranking Task ◽  
Handling Methods ◽  
Selection Of ◽  
Marketing Educators

Free-riding is a serious challenge in group projects. While there are various methods to reduce free-riding, marketing educators still face a difficult task when selecting an appropriate method for their course. In this study, we propose a students’ preferences-based approach that supports marketing educators with the selection of methods to detect and handle free-riding. To measure these preferences, students completed an online survey based on a choice task about two methods to detect free-riding and a ranking task about four methods to handle free-riding ( n = 254). Their answers were analyzed using chi-squared tests, Borda scores, and rank-ordered logit models. The results show that (a) neither Dutch nor international students have a clear preference for one of the two detection methods (the reporting system vs. the process evaluation system), (b) grade discussion (a possible reduction of the free-rider’s grade based on a conversation with the course coordinator about each student’s contribution) is the most preferred method to handle free-riding, and (c) international students have a stronger preference for stricter handling methods. Marketing educators can apply the proposed approach, or use our specific findings, for designing methods to reduce free-riding in their courses.

Potential of enzymes or a centrifuged rumen fluid to estimate proteolysis of foods

1998 ◽  
Vol 22 ◽  
pp. 120-122
Author(s):  
A. S. Chaudhry
Keyword(s):  
Rumen Fluid ◽  
Food Proteins ◽  
The Past ◽  
Ruminal Digestion ◽  
Selection Of ◽  
In Sacco

The need to develop an in vitro method to simulate ruminal digestion of protein foods has long been recognized. An in vitro method must be more rapid, consistent and convenient than in sacco methods. Purified enzymes have been examined in the past to estimate in vitro degradability of protein foods (Poos-Floyd et al., 1985; Aufrere et al., 1991; Luchini et al., 1996) or their fractions (Chaudhry and Webster, 1994). However, the selection of an appropriate enzyme for a range of foodstuffs remains to be realized. This study examined the potential of two enzymes and a centrifuged rumen fluid (CRF) to estimate proteolysis of food proteins.

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