scholarly journals Utilization of Neem Leaf Extract on Biosynthesis of Iron Oxide Nanoparticles

Molecules ◽  
2019 ◽  
Vol 24 (20) ◽  
pp. 3803 ◽  
Author(s):  
Nur Diyana Syazwani Zambri ◽  
Nurul Izza Taib ◽  
Famiza Abdul Latif ◽  
Zakiah Mohamed
Keyword(s):  
Electron Microscope ◽  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Magnetite Nanoparticles ◽  
Leaf Extract ◽  
Xrd Analysis ◽  
Oxide Nanoparticles ◽  
Spectra Analysis ◽  
X Ray ◽  
Average Size

The present work reports the successful synthesis of biosynthesized iron oxide nanoparticles (Fe3O4-NPs) with the use of non-toxic leaf extract of Neem (Azadirachta indica) as a reducing and stabilizing agent. The successful synthesis was confirmed by infrared spectra analysis with strong peak observed between 400–600 cm−1 that corresponds to magnetite nanoparticles characteristics. X-ray diffraction (XRD) analysis revealed that iron oxide nanoparticles were of high purity with crystalline cubic structure phases in nature. Besides, the average size of magnetite nanoparticles was observed to be 9–12 nm with mostly irregular shapes using a transmission electron microscope (TEM) and was supported by field emission scanning electron microscope (FESEM). Energy dispersive X-ray analysis shown that the elements iron (Fe) and oxygen (O) were present with atomic percentages of 33.29% and 66.71%, respectively. From the vibrating sample magnetometer (VSM) analysis it was proven that the nanoparticles exhibited superparamagnetic properties with a magnetization value of 73 emu/g and the results showed superparamagnetic behavior at room temperature, suggesting potential applications for a magnetic targeting drug delivery system.

scholarly journals Biogenic iron oxide nanoparticles enhance callogenesis and regeneration pattern of recalcitrant Cicer arietinum L.

PLoS ONE ◽  
2020 ◽  
Vol 15 (12) ◽  
pp. e0242829
Author(s):  
Samra Irum ◽  
Nyla Jabeen ◽  
Khawaja Shafique Ahmad ◽  
Saima Shafique ◽  
Talha Farooq Khan ◽  
...  
Keyword(s):  
Iron Oxide ◽  
Cicer Arietinum ◽  
Iron Oxide Nanoparticles ◽  
Shoot Regeneration ◽  
Callus Induction ◽  
Leaf Extract ◽  
Oxide Nanoparticles ◽  
Root Induction ◽  
X Ray ◽  
Embryo Axes

This study is the first report on the biosynthesized iron oxide nanoparticles (IONPs) which mediate in-vitro callus induction and shoot regeneration in economically important recalcitrant chickpea crop (Cicer arietinum L.). Here, we used leaf extract of Cymbopogon jwarancusa for the synthesis of IONPs in order to achieve a better biocompatibility. The bioactive compounds in C. jwarancusa leaf extract served as both reducing and capping agents in the fabrication process of IONPs. Field emission scanning electron microscopy (FE-SEM) revealed rods like surface morphology of IONPs with an average diameter of 50±0.2 nm. Energy-dispersive X-ray spectroscopy (EDS) depicted formation of pure IONPs with 69.84% Fe and 30.16% O2. X-ray diffractometry (XRD) and attenuated total reflectance-fourier transform infrared (ATR-FTIR) validate the crystalline structure, chemical analysis detect the presence of various biomolecular fingerprints in the as synthesized IONPs. UV-visible absorption spectroscopy depicts activity of IONPs under visible light. Thermo-gravimetric analysis (TGA) displayed thermal loss of organic capping around 500°C and confirmed their stabilization. The biosynthesized IONPs revealed promising results in callus induction, shoot regeneration and root induction of chickpea plants. Both chickpea varieties Punjab-Noor 09 and Bittle-98 explants, Embryo axes (EA) and Embryo axes plus adjacent part of cotyledon (EXC) demonstrated dose-dependent response. Among all explants, EXC of Punjab-Noor variety showed the highest callogenesis (96%) and shoot regeneration frequency (88%), while root induction frequency was also increased to 83%. Iron content was quantified in regenerated chickpea varieties through inductively coupled plasma-optical emission spectrometry. The quantity of iron is significantly increased in Punjab-Noor regenerated plants (4.88 mg/g) as compare to control treated plants (2.42 mg/g). We found that IONPs enhance chickpea growth pattern and keep regenerated plantlets infection free by providing an optimum environment for rapid growth and development. Thus, IONPs synthesized through green process can be utilized in tissue culture studies in other important recalcitrant legumes crops.

scholarly journals Structural Characterization, Antimicrobial and Antioxidant Assay of Biogenically Synthesized Maghemite (γ-Fe2O3) Nanoparticles

2021 ◽  
pp. 32-41
Author(s):  
A. Leema Rose ◽  
B. Shabushree ◽  
Preeja P. Thattil
Keyword(s):  
Antimicrobial Activity ◽  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Leaf Extract ◽  
Ferrous Sulphate ◽  
Diffusion Method ◽  
Oxide Nanoparticles ◽  
Fe2o3 Nanoparticles ◽  
X Ray

Aims: The present study focused on the optical and morphological characterization, antioxidant and antimicrobial activities of the biogenically synthesized iron oxide nanoparticles.  Methods: The preliminary phytochemical screening was done for the leaf extract of Annona reticulate L. The leaf extract and Ferrous Sulphate heptahydrate were used to synthesize the iron oxide nanoparticles under room temperature. The determination of antioxidant activity was done using DPPH free radical scavenging assay and the determination of antimicrobial activity using disc diffusion method. Results: The UV-visible spectra showed the sharp absorption peak at 278 nm. The Fourier-transform infrared spectroscopy studies revealed the role of phytochemical constituents in the leaf extract for the iron oxide nanoparticles formation.  X-ray diffraction pattern showed the presence of γ phase of Fe2O3 nanoparticles. Scanning electron microscope analysis showed the moderately spherical morphology of γ-Fe2O3 nanoparticles and Energy-dispersive X-ray peaks showed the presence of iron and oxygen in the synthesized nanoparticles.  Particle size analysis showed that the synthesized γ-Fe2O3possessed an average size of 115.9 nm. Conclusion: The synthesized γ-Fe2O3 nanoparticles have potential antioxidant and antimicrobial activity.

scholarly journals Green synthesis of iron oxide nanoparticles using Platanus orientalis leaf extract for antifungal activity

2019 ◽  
Vol 8 (1) ◽  
pp. 38-45 ◽  
Author(s):  
Henam Sylvia Devi ◽  
Muzaffar Ahmad Boda ◽  
Mohammad Ashraf Shah ◽  
Shazia Parveen ◽  
Abdul Hamid Wani
Keyword(s):  
Electron Microscopy ◽  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Leaf Extract ◽  
Oxide Nanoparticles ◽  
X Ray Diffraction ◽  
X Ray ◽  
Transmission Electron ◽  
Platanus Orientalis ◽  
Oxide Particles

Abstract In this report, aqueous phase green synthesis of iron oxide nanoparticle utilizing Platanus orientalis is elucidated for the first time. The phytoconstituents of the P. orientalis leaf extract serve a dual role as reducing and capping agent during the fabrication of iron oxide nanoparticles. The role of the leaf extract in the synthesis of iron oxide has been briefly demonstrated in this work. The tailored iron oxide particles were characterized using X-ray diffraction, scanning electron microscopy, transmission electron microscopy, energy dispersive X-ray analysis, infrared spectroscopy, ultraviolet-visible spectroscopy, and dynamic light scattering technique. Nonetheless, X-ray diffraction pattern reveals the mixed phase nature of the ensuing iron oxide, i.e. α-Fe2O3 and γ-Fe2O3. The spherical oxide particles have an average diameter of 38 nm as determined from transmission electron microscopy. Infrared spectroscopy results confirmed the stabilization of iron oxide nanoparticles by the phytochemicals present in the leaf extract. Iron oxide nanoparticles show significant antifungal activity against Aspergillus niger and Mucor piriformis, employed as model fungi, but found to be more active toward M. piriformis.

Effect of Annealing on Structural Properties of Fe3O4 Ferrite Nanoparticles

2018 ◽  
Vol 24 (8) ◽  
pp. 5748-5751
Author(s):  
Ravita ◽  
Amita ◽  
Ashok Kumar ◽  
Pawan S Rana
Keyword(s):  
Particle Size ◽  
Electron Microscope ◽  
Iron Oxide ◽  
Structural Properties ◽  
Iron Oxide Nanoparticles ◽  
Annealing Treatment ◽  
Precipitation Method ◽  
Oxide Nanoparticles ◽  
X Ray Diffraction ◽  
X Ray

Nano-crystalline Fe3O4 particles has been synthesized by chemical co-precipitation method. The synthesized samples were annealed at different temperature 300 °C, 500 °C, 700 °C. The effect of annealing temperature on structural properties of synthesized sample has been studied by various analytical techniques like X-ray diffraction (XRD), scanning electron microscope (SEM), transmission electron microscope and Fourier transform infrared spectroscopy (FTIR). The X-ray diffraction patterns confirm the synthesis of single crystalline phase of Fe3O4 nanoparticles. The crystallite size of synthesized iron oxide nanoparticles is about 7 nm. The crystallinity of iron oxide nanoparticles is enhanced by annealing treatment which is also confirmed by corresponding SEM and TEM micrographs. A phase transition from magnetite (Fe3O4) to hematite (α-F2O3) is observed when the samples are annealed above 500 °C. The fundamental groups of the iron oxide and annealed samples have been identified from FTIR spectrum. The particle size calculated from TEM images for the Fe3O4 sample varies in the range 5–20 nm and it has been observed that the particle size increases on annealing.

scholarly journals Macrophage-Laden Gold Nanoflowers Embedded with Ultrasmall Iron Oxide Nanoparticles for Enhanced Dual-Mode CT/MR Imaging of Tumors

Pharmaceutics ◽  
2021 ◽  
Vol 13 (7) ◽  
pp. 995
Author(s):  
Yucheng Peng ◽  
Xiaomeng Wang ◽  
Yue Wang ◽  
Yue Gao ◽  
Rui Guo ◽  
...  
Keyword(s):  
Iron Oxide ◽  
Mr Imaging ◽  
Iron Oxide Nanoparticles ◽  
Colloidal Stability ◽  
Pamam Dendrimer ◽  
Great Promise ◽  
Oxide Nanoparticles ◽  
Dual Mode ◽  
Gold Nanoflowers ◽  
Average Size

The design of multimodal imaging nanoplatforms with improved tumor accumulation represents a major trend in the current development of precision nanomedicine. To this end, we report herein the preparation of macrophage (MA)-laden gold nanoflowers (NFs) embedded with ultrasmall iron oxide nanoparticles (USIO NPs) for enhanced dual-mode computed tomography (CT) and magnetic resonance (MR) imaging of tumors. In this work, generation 5 poly(amidoamine) (G5 PAMAM) dendrimer-stabilized gold (Au) NPs were conjugated with sodium citrate-stabilized USIO NPs to form hybrid seed particles for the subsequent growth of Au nanoflowers (NFs). Afterwards, the remaining terminal amines of dendrimers were acetylated to form the dendrimer-stabilized Fe3O4/Au NFs (for short, Fe3O4/Au DSNFs). The acquired Fe3O4/Au DSNFs possess an average size around 90 nm, display a high r1 relaxivity (1.22 mM−1 s−1), and exhibit good colloidal stability and cytocompatibility. The created hybrid DSNFs can be loaded within MAs without producing any toxicity to the cells. Through the mediation of MAs with a tumor homing and immune evasion property, the Fe3O4/Au DSNFs can be delivered to tumors more efficiently than those without MAs after intravenous injection, thus significantly improving the MR/CT imaging performance of tumors. The developed MA-mediated delivery system may hold great promise for enhanced tumor delivery of other contrast agents or nanomedicines for precision cancer nanomedicine applications.

Green synthesis of iron oxide nanoparticles by aqueous leaf extract of Daphne mezereum as a novel dye removing material

2018 ◽  
Vol 124 (5) ◽  
Author(s):  
Nasrin Beheshtkhoo ◽  
Mohammad Amin Jadidi Kouhbanani ◽  
Amir Savardashtaki ◽  
Ali Mohammad Amani ◽  
Saeed Taghizadeh
Keyword(s):  
Iron Oxide ◽  
Green Synthesis ◽  
Iron Oxide Nanoparticles ◽  
Leaf Extract ◽  
Oxide Nanoparticles ◽  
Aqueous Leaf Extract
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