scholarly journals Optimization of Ultrasonic-Assisted Extraction and Purification of Zeaxanthin and Lutein in Corn Gluten Meal

Molecules ◽  
2019 ◽  
Vol 24 (16) ◽  
pp. 2994 ◽  
Author(s):  
Litao Wang ◽  
Weihang Lu ◽  
Jiali Li ◽  
Jinxia Hu ◽  
Ruifang Ding ◽  
...  
Keyword(s):  
Large Scale ◽  
High Efficiency ◽  
Total Content ◽  
Extraction Process ◽  
Extraction Time ◽  
Extraction Temperature ◽  
Corn Gluten Meal ◽  
Wide Range ◽  
Corn Gluten ◽  
Ultrasonic Assisted

Zeaxanthin and lutein have a wide range of pharmacological applications. In this study, we conducted systematic experimental research to optimize antioxidant extraction based on detection, extraction, process amplification, and purification. An ultrasonic-assisted method was used to extract zeaxanthin and lutein with high efficiency from corn gluten meal. Firstly, the effects of solid-liquid ratio, extraction temperature, and ultrasonic extraction time on the extraction of zeaxanthin were investigated in single-factor experiments. The optimization extraction parameters of zeaxanthin and lutein with ethanol solvent were obtained using the response surface methodology (RSM) as follows: liquid–solid ratio of 7.9:1, extraction temperature of 56 °C, and extraction time of 45 min. The total content of zeaxanthin and lutein was 0.501%. The optimum extraction experimental parameters were verified by process amplification, and we confirmed that the parameters of the extraction process optimized using the RSM design are reliable and precise. Zeaxanthin and lutein from crude extract of corn gluten were separated and purified using silica gel column chromatography with the purity of zeaxanthin increasing from 0.28% to 31.5% (about 110 times) and lutein from 0.25% to 16.3% (about 65 times), which could be used for large-scale industrial production of carotenoids.

Optimization of Murrayafoline A ethanol extraction process from the roots of Glycosmis stenocarpa, and evaluation of its Tumorigenesis inhibition activity on Hep-G2 cells

2021 ◽  
Vol 19 (1) ◽  
pp. 830-842
Author(s):  
Quoc Toan Tran ◽  
The Dan Pham ◽  
Thanh Duong Nguyen ◽  
Van Huyen Luu ◽  
Huu Nghi Do ◽  
...  
Keyword(s):  
Large Scale ◽  
Extraction Efficiency ◽  
Raw Materials ◽  
Biological Activities ◽  
Extraction Process ◽  
Extraction Time ◽  
Extraction Temperature ◽  
Hep G2 ◽  
Independent Parameters

Abstract Glycosmis stenocarpa is a species of shrub found in the Northern provinces of Vietnam. Its roots contain different carbazolic derivatives, mainly Murrayafoline A (Mu-A), which exhibits valuable biological activities. In this study, we performed an extraction of Mu-A from the roots of G. stenocarpa and optimized this process using response surface methodology (RSM) according to a central composite design, with three independent parameters including extraction time (min), extraction temperature (°C), and solvent/material ratio (mL/g). Two dependent variables were the Mu-A content (mg/g raw materials) and extraction efficiency (%). The optimal conditions to extract Mu-A were found to be as follows: extraction temperature, 67°C; extraction time, 165 min; and solvent/material ratio, 5:1. Under these conditions, the Mu-A content and extraction efficiency were 38.94 ± 1.31 mg/g raw materials and 34.98 ± 1.18%, respectively. Mu-A exhibited antiproliferation and antitumor-promoting activity against the HepG-2 cell line. The present optimization work of Mu-A extraction from G. stenocarpa roots contributed to the attempt of designing a large-scale extraction process for the compound and further exploitation of its potential in vivo applications.

Optimization of Ultrasonic-Assisted Extraction of Polysaccharides from Ottelia acuminata (Gagnep.) Dandy Using RSM

2011 ◽  
Vol 396-398 ◽  
pp. 292-296
Author(s):  
Ai Shi Zhu
Keyword(s):  
Processing Parameters ◽  
Extraction Time ◽  
Extraction Temperature ◽  
Independent Variables ◽  
Solid Ratio ◽  
Assisted Extraction ◽  
Ultrasonic Technology ◽  
Ultrasonic Assisted ◽  
Experimental Yield ◽  
Ultrasonic Assisted Extraction

Ultrasonic technology was applied to polysaccharides extraction from Ottelia acuminata (Gagnep.) Dandy and Response Surface Methodology (RSM) was used to optimize the effects of processing parameters on polysaccharides yields. Three independent variables such as liquid-solid ratio (ml/g, X1), extraction temperature (°C, X2) and extraction time (hour, X3) were investigated respectively. The statistical analysis indicated that the three variables and the quadratic of X1 and X3 had significant effects on the yields and followed by the significant interaction effects between the variables of X1 and X3, X2 and X3 (p<0.05). A mathematical model with high determination coefficient was gained. The optimal extraction conditions of polysaccharides were determined as follows: liquid-solid ratio 43 ml/g, extraction temperature 90 °C and extraction time 3.45 hours. Under these conditions, the experimental yield of polysaccharides was 107.44 mg/g, which was agreed closely with the predicted value 108.71 mg/g.

scholarly journals Optimization of the extraction of natural phenolic antioxidants from the seeds of Tamarindus indica L. - an undervalued by product of food processing - using response surface methodology

2018 ◽  
Vol 62 (1) ◽  
pp. 67-74 ◽  
Author(s):  
Atreyi Sarkar ◽  
Uma Ghosh
Keyword(s):  
Response Surface Methodology ◽  
Response Surface ◽  
Extraction Time ◽  
Phenolic Antioxidants ◽  
Extraction Temperature ◽  
Tamarindus Indica ◽  
Solvent Concentration ◽  
Antioxidant Power ◽  
Wide Range ◽  
Ferric Reducing Antioxidant Power

The seeds of Tamarindus indica are known to possess a wide range of phenolic compounds with high antioxidant activity as measured by the ferric reducing antioxidant power (FRAP). In the present study, the optimum conditions for the extraction of crude phenolic antioxidants from Tamarind seed were determined using response surface methodology (RSM). A central composite design (CCD) was used to investigate the effects of four independent variables, namely concentration of extractable solids in solvent (g/ml; X1), extraction time (h; X2), extraction temperature (°C; X3) and solvent concentration (%, v/v; X4) on the responses of total polyphenol content (TPC) and FRAP. The CCD consisted of 30 experimental runs. A second-order polynomial model was used for predicting the responses. Canonical analysis of the surface responses revealed that the predicted optimal conditions for the maximal yield of TPC and FRAP were concentration of extractable solids in solvent of 0.049 g/ml, extraction time of 3.24 h, extraction temperature of 45 °C and a solvent concentration of 50%. The experimental values in the optimised condition coincided with the predicted ones within a 95% confidence interval, hence indicating the suitability of the model and the success of RSM in optimizing the extraction parameters.

scholarly journals Extraction Process of Polyphenols from Soybean (Glycine max L.) Sprouts: Optimization and Evaluation of Antioxidant Activity

Processes ◽  
2019 ◽  
Vol 7 (8) ◽  
pp. 489 ◽  
Author(s):  
Xuan Tien Le ◽  
Vo Luu Lan Vi ◽  
Tran Quoc Toan ◽  
Long Giang Bach ◽  
Tran Thanh Truc ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Ethanol Concentration ◽  
Dry Weight ◽  
Extraction Process ◽  
Extraction Time ◽  
Extraction Temperature ◽  
Polyphenol Content ◽  
Experimental Conditions ◽  
Total Polyphenol ◽  
Total Polyphenol Content

This research aimed to optimize the total polyphenol content (TPC) extracted from soybean sprout powder under different experimental parameters, including ethanol concentration (60–100% v/v), extraction temperature (40–80 °C), extraction time (15–150 min), material:solvent ratio (1:4–1:10 g/mL), the number extraction cycles (1, 2 and 3 times), the age of sprout (0–7 days), and the used part of the sprout (cotyledon, hypocotyl, or radicle). The obtained results were used in response surface methodology, in combination with a central composite design, to model the total polyphenol content (TPC) with respect to three variables, including ethanol concentration, extraction temperature, and material:solvent ratio. The experimental conditions for optimal recovery of TPC consisted of ethanol concentration of 88% (v/v), extraction temperature of 59 °C, material:solvent ratio of 1:6.5 g/mL, extraction time of 60 min, and 2 cycles of maceration. In addition, for maximal TPC, the sprout should undergo the germination of 5 days and the radicle fraction should be used. Based on the suggested optimum conditions, the obtained and verified TPC was 19.801 mg genistein (GE)/g dry weight (d.w.). The obtained dried extract also exhibited low antioxidant activity.

scholarly journals The Effect of Operating Conditions on Curcumin Extracted from Turmeric by Hydrothermal Extraction

2019 ◽  
Vol 125 ◽  
pp. 19001
Author(s):  
Mohamad Endy Yulianto ◽  
Rizka Amalia ◽  
Vita Paramita ◽  
Indah Hartati ◽  
Nissa Ayu Maulinda ◽  
...  
Keyword(s):  
High Efficiency ◽  
Economic Value ◽  
Bioactive Compound ◽  
Extraction Process ◽  
Operating Conditions ◽  
Extraction Temperature ◽  
Liquid Ratio ◽  
High Concentration ◽  
Solid Liquid ◽  
Hydrothermal Extraction

Turmeric has a bioactive compound namely curcuminoid. It has many pharmacology effects such as anticancer, antidiabetic, antioxidant, hypolipidemic, anti-inflammatory, antimicrobial, antifertility, anti-venom, anti-coagulant, anti-HIV hepatoprotective, nephroprotective, and anticoagulant properties. To increase the economic value of turmeric, it is necessary to develop a hydrothermal extraction process of turmeric’s active compound. The advantages of hydrothermal extraction were inexpensive, abundant availability, high purity, non-toxic, and easy to handle. This research aims to study the effect of operating conditions : temperature (130-150oC), time (10-40 minutes) and solid:liquid ratio (1:10 and 1:12) on the bioactive compounds of turmeric extracted from hydrothermal extraction process. Generally, high extraction yield was obtained at higher extraction temperature (140 and 150oC). Under these conditions, with a lower solid : liquid ratio (1:10), high concentration of curcumin is produced. Further, a higher solid : liquid ratio will likely produce the opposite result, except when it operates at low extraction temperature. The high temperature of the pressurized liquid water can reduce the viscosity and surface tension of water so it will increase the diffusion rates and absorption. The higher the solid:liquid ratio, the greater the different concentration between interior and exterior cell, which promote the high efficiency of diffusion process.

ULTRASONIC-ASSISTED EXTRACTION OF OIL FROM CALOPHYLLUM INOPHYLLUM SEEDS: OPTIMIZATION OF PROCESS PARAMETERS

2016 ◽  
Vol 78 (10) ◽  
Author(s):  
Faiznur Mohd Fuad ◽  
Mashitah Mat Don
Keyword(s):  
Solvent Extraction ◽  
Extraction Time ◽  
Ultrasonic Power ◽  
Extraction Temperature ◽  
Calophyllum Inophyllum ◽  
Power Extraction ◽  
Optimization Of Process Parameters ◽  
Assisted Extraction ◽  
Ultrasonic Assisted ◽  
Ultrasonic Assisted Extraction

Calophyllum inophyllum (C. inophyllum) is a plant known as “Penaga Laut” in Malaysia. Its seeds contain valuable oil that serve as a potential alternative sources for vegetable oil. In this study, C. inophyllum seeds oil was extracted using an ultrasonic-assisted extraction (UAE) technique. The optimization of extraction parameters namely different types of solvent, extraction time, ultrasonic power, extraction temperature and liquid to solid (L/S) ratio were performed using one-factor-at-a-time (OFAT) method. The optimum extraction conditions obtained were n-hexane as a solvent, extraction time 20 min, ultrasonic power 210 W, extraction temperature 40°C and L/S ratio 20 ml/g, with an oil yield 55.44 ± 0.53 %.

In situ and real-time monitoring of an ultrasonic-assisted enzymatic hydrolysis process of corn gluten meal by a miniature near infrared spectrometer

2017 ◽  
Vol 9 (25) ◽  
pp. 3795-3803 ◽  
Author(s):  
Lin Luo ◽  
Yanyan Zhang ◽  
Kai Wang ◽  
Haile Ma ◽  
Mingsheng Dong
Keyword(s):  
Enzymatic Hydrolysis ◽  
Real Time ◽  
Near Infrared ◽  
Corn Gluten Meal ◽  
Hydrolysis Process ◽  
Corn Gluten ◽  
Ultrasonic Assisted ◽  
Infrared Spectrometer ◽  
Near Infrared Spectrometer

Ultrasound treatment during proteolysis could facilitate enzymatic hydrolysis.

scholarly journals Antioxidant Activity of Extract from Ultrasonic-Assisted Extraction of Durian Peels

2018 ◽  
Vol 5 (2) ◽  
Author(s):  
Bambang Kunarto ◽  
Ely Yuniarti Sani
Keyword(s):  
Antioxidant Activity ◽  
Total Phenolics ◽  
Extraction Process ◽  
Extraction Time ◽  
Total Flavonoids ◽  
Assisted Extraction ◽  
Ultrasonic Assisted ◽  
Total Flavonoids Content ◽  
Phenolics Content ◽  
Ultrasonic Assisted Extraction

The increase in durian production results in the accumulation of durian peel waste. The bioactive component of durian peel has the potential to be used as an antioxidant. Thus, there is a need to carry out an extraction process to obtain  bioactive compounds from durian peel. However, conventional extraction methods cause damage to phenolic compounds due to oxidation, hydrolysis and ionization reactions during the extraction process. Therefore, durian peel extraction was carried out using ultrasonic assisted extraction method (UAE) in this study. The purpose of this study was to investigate the effect of varying ratios of durian peel to ethanol solvents and extraction time on the yield, total phenolics content, total flavonoids content and antioxidant activity. The results of the research data were analyzed using a two-factor completely randomized design, which included variations of the ratio of durian peel to ethanol solvents and extraction time The Duncan’s New Multiple Range Test (DNMRT) was carried out as a follow up test to determine the differences in each treatment at a significance level of 0.05. The results showed that the best treatment for peel extraction using ultrasonic assisted extraction was a 1: 9 ratio of durian peel to ethanol at an extraction time of 20 minutes. The extraction of durian peel under this condition gave the highest yield of 12.77 ± 0.16%, antioxidant activity (IC50) of 38.33 ± 0.12 ppm, total phenolic content of 63.30 ± 0.08 mgGAE / g and total flavonoids content of 47.53 ± 0.48 mgQE / g. In addition, total phenolics content and total flavonoid content showed a strong correlation to the antioxidant activity of durian peel extract.

scholarly journals Research on the Principle and Cooperative Processing Method of MRS Multisystem Joint Detection

Sensors ◽  
2021 ◽  
Vol 21 (20) ◽  
pp. 6725
Author(s):  
Cong Li ◽  
Zhaofa Zeng ◽  
Zhuo Wang ◽  
Xiaofeng Yi
Keyword(s):  
Large Scale ◽  
High Efficiency ◽  
Joint Detection ◽  
Multiple Systems ◽  
Work Area ◽  
Magnetic Resonance Sounding ◽  
Wide Range ◽  
Working Together ◽  
Working Distance ◽  
Measurement Efficiency

Magnetic resonance sounding (MRS) technology is the only geophysical means to directly and quantitatively detect groundwater and has achieved good results in hydrogeological prospecting applications. In recent years, researchers have conducted considerable research on the efficiency of a single instrument, yielding certain results. However, the overall work efficiency of this method has not been effectively determined in its application to a large-scale survey. Hence, we propose both a joint detection method for MRS that determines the minimum working distance when multiple systems operate simultaneously and a collaborative measurement method of dual systems operating simultaneously in a fixed range of work areas. The cooperative working mode of the instruments is tested in the detection area, and the working mode proposed in this paper is shown to effectively avoid measurement interference between systems. Compared with the working mode of a single set of instruments, the measurement efficiency is more than doubled. Through this research, the feasibility of multiple MRS instruments working together in the same work area is verified, which provides effective technical support for the rapid and high-efficiency utilization of MRS over a wide range of measurement areas.

scholarly journals Optimization of Extraction Conditions of Bioactive Compounds by Ultrasonic-Assisted Extraction from Artichoke Wastes

2021 ◽  
Vol 68 (3) ◽  
pp. 658-666
Author(s):  
Izzet Turker ◽  
Hilal Isleroglu
Keyword(s):  
Antioxidant Capacity ◽  
Bioactive Compounds ◽  
Extraction Process ◽  
Extraction Yield ◽  
Extraction Time ◽  
Total Phenolic ◽  
Assisted Extraction ◽  
Ultrasonic Assisted ◽  
Extraction Processes ◽  
Ultrasonic Assisted Extraction

In this study, bioactive compounds were extracted by ultrasonic-assisted extraction and classical extraction processes using distilled water as solvent from artichoke leaves which are considered as agricultural wastes. Antioxidant capacity, total phenolic and total flavonoid content values of the obtained bioactive extracts were determined, and extraction yields and times were evaluated to compare the extraction processes. Also, the optimum extraction conditions of ultrasonic-assisted extraction (extraction time and ultrasonic power) which provide the highest extraction yield were determined using D-optimal design by ‘desirability’ function approach. According to the results, bioactive extracts having high antioxidant capacity were obtained at shorter times and higher extraction yields were achieved by ultrasonic-assisted extraction process than classical extraction. The highest extraction yield was estimated as 98.46% with an application of 20.05 minutes of extraction time and 65.02% of ultrasonic amplitude for the ultrasonic-assisted extraction process.

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