scholarly journals Exploiting the Nucleophilicity of the Nitrogen Atom of Imidazoles: One-Pot Three-Component Synthesis of Imidazo-Pyrazines

Molecules ◽  
2019 ◽  
Vol 24 (10) ◽  
pp. 1959
Author(s):  
Ubaldina Galli ◽  
Rejdia Hysenlika ◽  
Fiorella Meneghetti ◽  
Erika Del Grosso ◽  
Sveva Pelliccia ◽  
...  
Keyword(s):  
Nitrogen Atom ◽  
Multicomponent Reaction ◽  
Room Temperature ◽  
High Energy ◽  
One Pot ◽  
Ion Channeling

A novel one-pot multicomponent reaction to synthesize substituted imidazopyrazines is described. In brief, 1H-(imidazol-5-yl)-N-substituted methanamines react with aldehydes and isocyanides in methanol at room temperature to give imidazopyrazine derivatives in excellent yields. The imidazole nitrogen atom was able to intercept the nascent nitrilium ion, channeling the reaction toward to the sole formation of imidazopyrazines, suppressing the competitive formation of other possible side products deriving from the reaction with the high-energy nitrilium ion. The number of examples and the variability of the nature of isocyanides, aldehydes, and amine components herein employed, witness the robustness of this novel methodology.

Growth of Thin Nickel Silicide Layers on Clean B-Doped Si(111) Surfaces at Room Temperature

1989 ◽  
Vol 160 ◽  
Author(s):  
L. Luo ◽  
G. A. Smith ◽  
W. M. Gibson
Keyword(s):  
Monte Carlo ◽  
Computer Simulations ◽  
Room Temperature ◽  
High Energy ◽  
Nickel Silicide ◽  
Growth Stages ◽  
Initial Growth ◽  
Fourth Layer ◽  
Ion Channeling ◽  
Thin Nickel

AbstractThe initial growth stages of Ni on clean B-doped Si(111) were studied at room temperature using high energy Ion channeling and Monte Carlo computer simulations of the Ni/Si interface. The results suggest that the first monolayer of Ni atoms diffuse to reaction sites in the fourth layer of the Si(111) substrate where nickel suicide growth begins. Further Ni deposition (up to ~ 3 ML) leads to the growth of NiSi2 which is thought to be a diffusion barrier that terminates further formation of NiSi2 at room temperature.

scholarly journals Application of One-Pot Three-Component Condensation Reaction for the Synthesis of New Organophosphorus–Sulfur Macrocycles

Synlett ◽  
2018 ◽  
Vol 29 (11) ◽  
pp. 1496-1501 ◽  
Author(s):  
J. Woollins ◽  
Guoxiong Hua ◽  
David Cordes ◽  
Alexandra Slawin
Keyword(s):  
Multicomponent Reaction ◽  
Room Temperature ◽  
Condensation Reaction ◽  
Synthesis Method ◽  
Membered Ring ◽  
One Pot ◽  
X Ray ◽  
Efficient Approach ◽  
Mild Conditions ◽  
Sulfur Heterocycles

An efficient approach has been developed for the synthesis of new phosphorus–sulfur heterocycles by a one-pot three-component condensation reaction of a four-membered-ring thionation reagent [Lawesson’s reagent or its ferrocene analogue (2,4-diferrocenyl-1,3,2,4-diathiadiphosphetane 2,4-disulfide)], an alkane- or arenedithiol, and a dihaloalkane at room temperature in the presence of triethylamine. The simple synthesis method with mild conditions (room temperature and normal reactant concentrations) enhances further the application of the multicomponent reaction in the preparation of novel phosphorus–sulfur heterocycles. Six representative X-ray structures confirmed the formation of these macrocycles.

ALLOY FORMATION OF ULTRATHIN Ni FILMS ON Al(111) SURFACE AT ROOM TEMPERATURE

1999 ◽  
Vol 06 (05) ◽  
pp. 781-786 ◽  
Author(s):  
Y. W. KIM ◽  
G. A. WHITE ◽  
R. REIBEL ◽  
R. J. SMITH
Keyword(s):  
Photoelectron Spectroscopy ◽  
Room Temperature ◽  
High Energy ◽  
Alloy Formation ◽  
Ion Scattering ◽  
Xps Spectra ◽  
Ion Channeling ◽  
Low Energy Ion Scattering ◽  
Nial Phase ◽  
Nial Alloy

The growth characteristics of ultrathin Ni films deposited on Al(111) surfaces at room temperature have been studied using high energy ion scattering/channeling (HEIS), X-ray photoelectron spectroscopy (XPS) and low energy ion scattering (LEIS). Ion channeling results show that Ni atoms deposited on the Al(111) surface react with Al substrate atoms to form two different Ni–Al alloys between 0 and 5.5 ML of Ni coverage. Alloy phases of Ni 2 Al 3 up to 1.5 ML and NiAl up to 5.5 ML were determined by XPS peak analysis. At higher Ni coverage, LEIS and XPS spectra suggest that islands of Ni metal were formed on the surface. Diffusion of Ni into the Al substrate or segregation of Al to the surface was observed during the alloy formation. The Ni 2 Al 3 phase was apparently transformed into the NiAl phase by the additional Ni deposition, and the islands of Ni metal formed on the Al-rich surface of the NiAl alloy.

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