scholarly journals Seven New Drimane-Type Sesquiterpenoids from a Marine-Derived Fungus Paraconiothyrium sporulosum YK-03

Molecules ◽  
2019 ◽  
Vol 24 (9) ◽  
pp. 1817 ◽  
Author(s):  
Li-Hua Zhang ◽  
Gang Chen ◽  
Yi Sun ◽  
Hai-Feng Wang ◽  
Jiao Bai ◽  
...  
Keyword(s):  
Ethyl Acetate ◽  
Diffraction Analysis ◽  
Aromatic Ring ◽  
Spectroscopic Data ◽  
Ethyl Acetate Extract ◽  
Fermentation Broth ◽  
X Ray Diffraction ◽  
X Ray ◽  
The Absolute ◽  
Circular Dichroism Data

Seven new drimane-type sesquiterpenoids, namely the sporulositols A–D (1–4), 6-hydroxydiaporol (5), seco-sporulositol (6) and sporuloside (7) were isolated from the ethyl acetate extract of fermentation broth for a marine-derived fungus Paraconiothyrium sporulosum YK-03. Their structures were elucidated by analysis of extensive spectroscopic data, and the absolute configurations were established by crystal X-ray diffraction analysis and comparisons of circular dichroism data. Among them, sporulositols A–E (1–4) and seco-sporulositol (6) represent the first five examples of a unique class of drimanic mannitol derivatives, while compounds 6 and 7 may represent two new series of natural drimanes, possessing an aromatic ring with a rare 4,5-secodrimanic skeleton and an unusual CH3-15 rearranged drimanic α-D-glucopyranside, respectively. Furthermore, the origin of mannitol moiety was investigated by reliable HPLC and NMR analyses.

scholarly journals A Pair of New Polyketide Enantiomers from Three Endolichenic Fungal Strains Nigrospora sphaerica, Alternaria alternata, and Phialophora sp

2016 ◽  
Vol 11 (6) ◽  
pp. 1934578X1601100 ◽  
Author(s):  
Jun-Wei He ◽  
Chuan-Xi Wang ◽  
Li Yang ◽  
Guo-Dong Chen ◽  
Dan Hu ◽  
...  
Keyword(s):  
Diffraction Analysis ◽  
Alternaria Alternata ◽  
Spectroscopic Methods ◽  
X Ray Diffraction ◽  
X Ray ◽  
Fungal Strains ◽  
The Absolute ◽  
Modified Mosher’S Method

A pair of new enantiomeric polyketides, (-)- and (+)-nigrosporaol A (1a and 1b), along with one related known compound, (±)-alternarienoic acid (2), were isolated from three endolichenic fungal strains, Nigrospora sphaerica (No.83-1-1-2), Alternaria alternata (No.58-8-4-1), and Phialophora sp.(No.96-1-8-1). Their structures, including the absolute configurations, were elucidated on the basis of spectroscopic methods, X-ray diffraction analysis, and the modified Mosher's method.

scholarly journals Anti-inflammatory Anthraquinones from the Crinoid Himerometra magnipinna

2015 ◽  
Vol 10 (2) ◽  
pp. 1934578X1501000
Author(s):  
Yen-You Lin ◽  
Su-June Tsai ◽  
Michael Y. Chiang ◽  
Zhi-Hong Wen ◽  
Jui-Hsin Su
Keyword(s):  
Single Crystal ◽  
Diffraction Analysis ◽  
Absolute Configuration ◽  
Spectroscopic Data ◽  
Test Compound ◽  
X Ray Diffraction ◽  
X Ray ◽  
Anti Inflammatory ◽  
Raw264.7 Macrophage

Chemical investigation of a crinoid Himerometra magnipinna has afforded three anthraquinones (1–3), including one new metabolite, (+)-rhodoptilometrin (1). The structures of these compounds were elucidated on the basis of their spectroscopic data and the absolute configuration of 1 was further confirmed by single-crystal X-ray diffraction analysis. In the in vitro anti-inflammatory effects test, compound 2 was found to significantly inhibit the accumulation of the pro-inflammatory iNOS protein of the LPS-stimulated RAW264.7 macrophage cells.

Nd3+ Doped LiCaAIF6 Single Crystal for Scintillator Application

2012 ◽  
Vol 508 ◽  
pp. 224-229 ◽  
Author(s):  
Takayuki Yanagida ◽  
Yoshisuke Futami ◽  
Noriaki Kawaguchi ◽  
Jan Pejchal ◽  
Yutaka Fujimoto ◽  
...  
Keyword(s):  
Single Crystal ◽  
Diffraction Analysis ◽  
Luminescence Spectrum ◽  
Single Phase ◽  
Grown Crystal ◽  
Light Yield ◽  
Transmittance Spectrum ◽  
X Ray Diffraction ◽  
X Ray ◽  
The Absolute

ααΑαNd3+ 0.5% Doped Single Crystal LiCaAlF6 Scintillator Was Grown by the Micro-Pulling down (µ-PD) Method. Powder X-Ray Diffraction Analysis Was Done and the Grown Crystal Was a Single Phase LiCaAlF6. it Was Cut and Polished to the Physical Dimension of 1 × 2 × 7 mm3. in Transmittance Spectrum, Nd3+ 5d-4f Absorption Observed at 175 Nm and the Transmittance Became 80% at Wavelength Longer than 180 Nm. Excited by 160 Nm, Nd3+ 5d-4f Emission Appeared at 180 Nm. X-Ray Induced Radio-Luminescence Spectrum Showed the Similar Feature with the Photoluminescence One. when Coupled with PMT and Irradiated by 241Am α-Ray, the Absolute Light Yield Resulted 100 Ph/5.5 Mev α.

scholarly journals Antioxidant Sesquiterpenes from Penicillium citreonigrum

2017 ◽  
Vol 12 (12) ◽  
pp. 1934578X1701201 ◽  
Author(s):  
Wei-Hua Yuan ◽  
Ying Zhang ◽  
Peng Zhang ◽  
Ru-Ru Ding
Keyword(s):  
Ascorbic Acid ◽  
Single Crystal ◽  
Diffraction Analysis ◽  
Mycophenolic Acid ◽  
Endophytic Fungus ◽  
Spectroscopic Data ◽  
X Ray Diffraction ◽  
X Ray ◽  
Antioxidant Capacities

A new chlorinated 11-noreremophilane-type sesquiterpene (1) together with 3-epiisopetasol, PR-amide and mycophenolic acid (2–4) were isolated from endophytic fungus Penicillium citreonigrum. The structures of 1–4 were elucidated by a combination of spectroscopic data and single-crystal X-ray diffraction analysis. Among them, compounds 1 and 4 showed moderate antioxidant capacities compared with ascorbic acid at 0.2 mM concentration.

scholarly journals New Iboga-Type Indole Alkaloids from Tabernaemontana divaricata

2019 ◽  
Vol 9 (6) ◽  
pp. 425-429 ◽  
Author(s):  
Xiang-Mei Li ◽  
Xian-Jun Jiang ◽  
Guo-Zhu Wei ◽  
Li-Hua Ren ◽  
Li-Xia Wang ◽  
...  
Keyword(s):  
Single Crystal ◽  
Diffraction Analysis ◽  
Circular Dichroism Spectrum ◽  
Spectroscopic Data ◽  
Indole Alkaloids ◽  
Data Interpretation ◽  
X Ray Diffraction ◽  
X Ray ◽  
Tabernaemontana Divaricata ◽  
Circular Dichroïsm

Abstract Two hitherto unknown iboga-type indole alkaloids, namely (3R)-7,19-di-epi-3-methoxytabernoxidine (1) and (3R,19R)-19-hydroxy-3-(2-oxopropyl)voacangine (2), together with eight known alkaloids (3–10), were isolated from the twigs and leaves of Tabernaemontana divaricata. Their structures were established on the basis of spectroscopic data interpretation, single crystal X-ray diffraction analysis and circular dichroism spectrum. Graphic Abstract

scholarly journals Diastereoselective Addition of Diazomethane to Zaluzanin A

2014 ◽  
Vol 9 (6) ◽  
pp. 1934578X1400900 ◽  
Author(s):  
Adriana Ortiz-León ◽  
J. Martín Torres-Valencia ◽  
J. Jesús Manríquez-Torres ◽  
José G. Alvarado-Rodríguez ◽  
Uvaldo Hernández-Balderas ◽  
...  
Keyword(s):  
Diffraction Analysis ◽  
Absolute Configuration ◽  
Sesquiterpene Lactones ◽  
Addition Product ◽  
Vibrational Circular Dichroism ◽  
X Ray Diffraction ◽  
X Ray ◽  
H Nmr ◽  
Diastereoselective Addition ◽  
The Absolute

The diastereoselectivity of diazomethane addition to the conjugated double bond of α,β-unsaturated sesquiterpene lactones was explored using zaluzanin A (1) as a model. Thus, the absolute configuration of 1 was assured by X-ray diffraction analysis including evaluation of Flack and Hooft parameters, and by vibrational circular dichroism spectroscopy of its diacetyl derivative 2, while the absolute configuration of the diazomethane addition product, zaluzanin A pyrazoline (3), was determined by evaluation of the 1H NMR chemical shift changes with respect to 1, and confirmed by X-ray diffraction analysis, again including evaluation of Flack and Hooft parameters.

scholarly journals Zopfiellasins A–D, Two Pairs of Epimeric Cytochalasins from Kiwi-Associated Fungus Zopfiella sp. and Their Antibacterial Assessment

Molecules ◽  
2021 ◽  
Vol 26 (18) ◽  
pp. 5611
Author(s):  
Jie-Yu Zhang ◽  
Juan He ◽  
Zheng-Hui Li ◽  
Tao Feng ◽  
Ji-Kai Liu
Keyword(s):  
Antibacterial Activity ◽  
Data Analysis ◽  
Single Crystal ◽  
Pseudomonas Syringae ◽  
Spectroscopic Data ◽  
Antibacterial Agents ◽  
X Ray Diffraction ◽  
X Ray ◽  
First Report ◽  
The Absolute

In our continuous search for antibacterial agents against Pseudomonas syringae pv. actinidiae (Psa) from kiwi-associated fungi, two pairs of epimeric cytochalasins, zopfiellasins A–D (1–4), were characterized from the fungus Zopfiella sp. The structures were established on the basis of spectroscopic data analysis, while the absolute configurations were determined by single-crystal X-ray diffraction. Compounds 1 and 3 exhibited antibacterial activity against Psa with MIC values of 25 and 50 μg/mL, respectively. This is the first report of anti-Psa activity of cytochalasin derivatives.

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