scholarly journals An Efficient Synthesis of Acenaphtho[1,2-b]indole Derivatives via Domino Reaction

Molecules ◽  
2018 ◽  
Vol 23 (11) ◽  
pp. 3045
Author(s):  
Guo-Ning Zhang ◽  
Xia Yuan ◽  
Weiping Niu ◽  
Mei Zhu ◽  
Juxian Wang ◽  
...  
Keyword(s):  
Domino Reaction ◽  
Indole Derivatives ◽  
Domino Reactions ◽  
Efficient Synthesis

A concise and efficient synthesis of acenaphtho[1,2-b]indole derivatives via the domino reactions of enaminones with acenaphthoquinone catalyzed by l-proline has been developed. This protocol has the advantages of good yields, operational convenience and high regioselectivity.

Domino Reactions of 1-Aroyl-3,4-dihydroisoquinolines with α,β-Unsaturated Aldehydes

Synthesis ◽  
2017 ◽  
Vol 49 (23) ◽  
pp. 5251-5257 ◽  
Author(s):  
Maria Matveeva ◽  
Tatiana Borisova ◽  
Alexander Titov ◽  
Lada Anikina ◽  
Svetlana Dyachenko ◽  
...  
Keyword(s):  
Microwave Irradiation ◽  
Domino Reaction ◽  
Domino Reactions ◽  
Efficient Synthesis ◽  
Unsaturated Aldehydes

An efficient synthesis of pyrrolo[2,1-a]isoquinolines by a domino reaction from a variety of 3,4-dihydropyrrolo[2,1-a]isoquinolines and α,β-unsaturated aldehydes in the absence of catalyst in good yields under microwave irradiation, is reported.

A solvent- and catalyst-free domino reaction for the efficient synthesis of 3-arylthiazolidine-2-thiones under microwave irradiation

RSC Advances ◽  
2015 ◽  
Vol 5 (110) ◽  
pp. 90451-90456 ◽  
Author(s):  
Sundaravel Vivek Kumar ◽  
Shanmugam Muthusubramanian ◽  
Subbu Perumal
Keyword(s):  
Microwave Irradiation ◽  
Domino Reaction ◽  
Domino Reactions ◽  
Efficient Synthesis ◽  
Facile Synthesis ◽  
Catalyst Free ◽  
Aryl Isothiocyanates

A facile synthesis of 4-hydroxy-3-arylthiazolidine-2-thiones through novel domino reactions of aryl isothiocyanates and 1,4-dithiane-2,5-diol under solvent- and catalyst-free microwave irradiation is reported.

scholarly journals Efficient synthesis of pyrazolopyridines containing a chromane backbone through domino reaction

2019 ◽  
Vol 15 ◽  
pp. 874-880
Author(s):  
Razieh Navari ◽  
Saeed Balalaie ◽  
Saber Mehrparvar ◽  
Fatemeh Darvish ◽  
Frank Rominger ◽  
...  
Keyword(s):  
Room Temperature ◽  
High Selectivity ◽  
Domino Reaction ◽  
Primary Amines ◽  
Efficient Synthesis ◽  
Atom Economy ◽  
Reaction Conditions ◽  
Efficient Approach ◽  
Three Component Reaction ◽  
High Yields

An efficient approach for the synthesis of pyrazolopyridines containing the aminochromane motif through a base-catalyzed cyclization reaction is reported. The synthesis was carried out through a three-component reaction of (arylhydrazono)methyl-4H-chromen-4-one, malononitrile, primary amines in the presence of Et3N at room temperature. However, carrying out the reaction under the same conditions without base led to a fused chromanyl-cyanopyridine. High selectivity, high atom economy, and good to high yields in addition to mild reaction conditions are the advantages of this approach.

Are fermentation products promising feedstock for high-density bio-fuel? domino reactions for upgrading aqueous acetone–butanol–ethanol mixtures

2020 ◽  
Vol 22 (18) ◽  
pp. 6137-6147
Author(s):  
Yahui Gong ◽  
Pingzhou Wang ◽  
Cai Wu ◽  
Jie Wang ◽  
Chun Shen
Keyword(s):  
Aqueous Acetone ◽  
High Density ◽  
Domino Reaction ◽  
Domino Reactions ◽  
Fermentation Products ◽  
Acetone Butanol Ethanol

Upgrading aqueous acetone–butanol–ethanol mixtures to high-density bio-fuels is realized via the three-step domino reaction in a green way.

Transition-Metal-Free, Intermolecular Azidoheteroarylation of Alkenes: Efficient Access to β-Azidoalkylated Quinoxalinones and Preliminary Antifungal Evaluation Against Magnaporthe grisea

Synthesis ◽  
2020 ◽  
Vol 52 (16) ◽  
pp. 2395-2409
Author(s):  
Weiwei Qin ◽  
Zhaodong Li ◽  
Yiming Du ◽  
Yue Chen ◽  
Yun-Lin Liu
Keyword(s):  
Transition Metal ◽  
Magnaporthe Grisea ◽  
Single Step ◽  
Domino Reaction ◽  
Efficient Synthesis ◽  
Metal Free ◽  
Efficient Access ◽  
First Time ◽  
Antibacterial Evaluation ◽  
Addition Pathway

An efficient, PhI(OAc)2-mediated, radical azidoheteroarylation of alkenes under transition-metal-free conditions is reported by employing TMSN3 and quinoxalin-2(1H)-ones as coupling partners. This domino reaction allows an efficient synthesis of valuable orangoazides containing quinoxalin-2(1H)-one derivatives and could be extended to phosphinyl-alkylated quinoxalin-2(1H)-one in a single step in moderate to excellent yields under mild conditions, as demonstrated by the preliminary antibacterial evaluation against Magnaporthe grisea for the first time. Mechanistic studies revealed that this transformation undergoes a cascade addition pathway controlled by a polar radical.

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