scholarly journals Phytochemical Constituents and Biological Activities of Melicope lunu-ankenda

Molecules ◽  
2018 ◽  
Vol 23 (10) ◽  
pp. 2708 ◽  
Author(s):  
Enas Mohamed Eliaser ◽  
Jun Hui Ho ◽  
Najihah Mohd. Hashim ◽  
Yaya Rukayadi ◽  
Gwendoline Cheng Lian Ee ◽  
...  
Keyword(s):  
Therapeutic Agent ◽  
Biological Activities ◽  
New Drugs ◽  
Tropical Regions ◽  
Traditional Medicines ◽  
Treatment Of Hypertension ◽  
Pure Compounds ◽  
Phytochemical Compounds ◽  
Phytochemical Constituents ◽  
Different Parts

Natural products, either pure compounds or standardized plant extracts, have provided opportunities for the discovery of new drugs. Nowadays, most of the world’s population still relies on traditional medicines for healthcare purposes. Plants, in particular, are always used as traditional medicine, as they contain a diverse number of phytochemicals that can be used for the treatment of diseases. The multicomponent feature in the plants is considered a positive phytotherapeutic hallmark. Hence, ethnopharmacognosy has been the focus for finding alternative treatments for diseases. Melicope lunu-ankenda, also known as Euodia lunu-ankenda, is widely distributed in tropical regions of Asia. Different parts of M. lunu-ankenda have been used for treatment of hypertension, menstrual disorder, diabetes, and fever, and as an emmenagogue and tonic. It has also been consumed as salad and as a condiment for food flavorings. The justification of use of M. lunu-ankenda in folk medicines is supported by its reported biological activities, including its cytotoxic, antibacterial, antioxidant, analgesic, antidiabetic, and anti-inflammatory activities. This review summarizes the phytochemical compounds isolated from various parts of M. lunu-ankenda, such as root and leaves, and also its biological activities, which could make the species a new therapeutic agent for some diseases, including diabetes, in the future.

scholarly journals Evaluation of Chemical Properties, Biological Activities and Ethnomedicinal uses of Cladostemon kirkii -

2020 ◽  
Vol 10 (5) ◽  
pp. 190-195
Author(s):  
Alfred Maroyi
Keyword(s):  
Biological Activities ◽  
Chemical Properties ◽  
Journal Articles ◽  
Scientific Publications ◽  
Medicinal Uses ◽  
Sexually Transmitted ◽  
Traditional Medicines ◽  
Online Databases ◽  
Phytochemical Compounds ◽  
Ethnomedicinal Uses

Cladostemon kirkii (Oliv.) Pax & Gilg is a shrub or a small tree widely used as traditional medicine in tropical Africa. This study is aimed at evaluating the chemical properties, biological activities and ethnomedicinal uses of C. kirkii. Results of the current study are based on data derived from several online databases such as Scopus, Google Scholar, PubMed and Science Direct, and pre-electronic sources such as scientific publications, books, dissertations, book chapters and journal articles. The articles published between 1960 and 2019 were used in this study. This study revealed that the bark, leaf, root and stem infusion and/or decoction of C. kirkii are mainly used as traditional medicines for boils, colds, gastro-intestinal problems, hypertension, ophthalmia, rheumatism, sexual dysfunction, abdominal pains, sexually transmitted infections, sores and wounds. Phytochemical compounds identified from the species include mearnsitrin, myricitrin, kaempferol-5-rhamnoside, kaempferin, kaempferol 3-gluco-7-rhamnoside, quercetin 3,7-dirhamnoside, quercetin 3-gluco-7-rhamnoside, choline, 3-hydroxyprolinebetaine and tetramethylammonium. Cladostemon kirkii should be subjected to detailed phytochemical, pharmacological and toxicological evaluations aimed at correlating its medicinal uses with its phytochemistry and pharmacological properties.

scholarly journals Structures and Bioactivities of Steroidal Saponins Isolated from the Genera Dracaena and Sansevieria

Molecules ◽  
2021 ◽  
Vol 26 (7) ◽  
pp. 1916
Author(s):  
Zaw Min Thu ◽  
Sann Myint Oo ◽  
Thinn Myat Nwe ◽  
Hnin Thanda Aung ◽  
Chabaco Armijos ◽  
...  
Keyword(s):  
Secondary Metabolites ◽  
Biological Activities ◽  
Ornamental Plants ◽  
Steroidal Saponins ◽  
Structural Motifs ◽  
Traditional Medicines ◽  
Wide Range ◽  
Bioactive Secondary Metabolites ◽  
Phytochemical Constituents ◽  
Anti Inflammatory

The species Dracaena and Sansevieria, that are well-known for different uses in traditional medicines and as indoor ornamental plants with air purifying property, are rich sources of bioactive secondary metabolites. In fact, a wide variety of phytochemical constituents have been isolated so far from about seventeen species. This paper has reviewed the literature of about 180 steroidal saponins, isolated from Dracaena and Sansevieria species, as a basis for further studies. Saponins are among the most characteristic metabolites isolated from the two genera. They show a great variety in structural motifs and a wide range of biological activities, including anti-inflammatory, anti-microbial, anti-proliferative effects and, in most case, remarkable cytotoxic properties.

scholarly journals LANNEA SCHIMPERI: REVIEW OF ITS BOTANY, MEDICINAL USES, PHYTOCHEMISTRY, AND BIOLOGICAL ACTIVITIES

2019 ◽  
pp. 31-36
Author(s):  
ALFRED MAROYI
Keyword(s):  
Cardiac Glycosides ◽  
Web Of Science ◽  
Biological Activities ◽  
Journal Articles ◽  
Tropical Africa ◽  
Pharmacological Activities ◽  
Medicinal Uses ◽  
Phytochemical Compounds ◽  
Phytochemical Constituents ◽  
The University

Lannea schimperi is a well-known fruit tree and medicinal plant in tropical Africa. The current study critically reviewed the botany, medicinal uses, phytochemistry, and pharmacological activities of L. schimperi. Literature on botany, medicinal uses, phytochemical and biological activities of L. schimperi were collected from multiple internet sources including Elsevier, Google Scholar, SciFinder, Web of Science, PubMed, BMC, ScienceDirect, and Scopus. Complementary information was gathered from pre-electronic sources such as books, book chapters, theses, scientific reports, and journal articles obtained from the University Library. This study revealed that the species is used as a source of fiber, edible fruits, and herbal medicine. Phytochemical compounds identified from the species include cyclohexenones, cardanols, alkaloids, anthocyanins, anthracene glycosides, carbohydrates, cardiac glycosides, carotenoids, condensed tannins, coumarins, flavonoids, phenolic glycosides, phenols, polyoses, polyuronoids, reducing sugars, saponins, steroids, tannins, triterpenoids, and volatile compounds. Pharmacological research revealed that extracts and phytochemical constituents isolated from L. schimperi have anesthetic, antibacterial, antifungal, anticoccidial, anti-inflammatory, antinociceptive, antioxidant, anti-trypanosoma, antiulcerogenic, cytotoxicity, and toxicity activities. L. schimperi should be subjected to detailed phytochemical, pharmacological, and toxicological evaluations aimed at correlating its medicinal uses with its phytochemistry and pharmacological activities of the species.

scholarly journals Plant description, phytochemical constituents and bioactivities of Syzygium genus: A review

2020 ◽  
Vol 18 (1) ◽  
pp. 1256-1281
Author(s):  
Ei Ei Aung ◽  
Alfinda Novi Kristanti ◽  
Nanik Siti Aminah ◽  
Yoshiaki Takaya ◽  
Rico Ramadhan
Keyword(s):  
Diffusion Method ◽  
Flower Buds ◽  
Antioxidant Power ◽  
Traditional Medicines ◽  
Brine Shrimp Lethality Assay ◽  
Diphenyltetrazolium Bromide ◽  
Ferric Reducing Antioxidant Power ◽  
Phytochemical Constituents ◽  
Different Parts ◽  
Agar Well Diffusion Method

AbstractThis article attempts to report native growth, plant description, phytochemical constituents and bioactivities of Syzygium aqueum, S. aromaticum, S. cumini, S. guineense and S. samarangense. Those are the large public species in the Syzygium genus and some of them have been used as traditional medicines. Different parts (leaves, seeds, fruits, barks, stem barks and flower buds) of each species plant are rich in phytochemical constituents such as flavonoids, terpenoids, tannins, glycosides and phenolics. Antioxidant, antidiabetic, anticancer, toxicity, antimicrobial, anti-inflammatory and anthelmintic activities are reported in various extracts (methanol, ethanol and aqueous) from different parts of Syzygium sp. The bioactivities were studied by using 1,1-diphenyl-2-picrylhydrazyl and ferric reducing antioxidant power assays for antioxidant, 5-(3-carboxymethoxyphenyl)-2-(4,5-dimethyl-thiazoly)-3-(4-sulfophenyl) tetrazolium and 3-(4,5-dimethylthiazol-2-yl)-2-5-diphenyltetrazolium bromide assays for anticancer, α-glucosidase and α-amylase inhibition assays for antidiabetic, agar well diffusion method for antimicrobial and brine shrimp lethality assay for toxicity. Moreover, this review shows that phytochemical constituents of each species significantly presented various bioactivities. Therefore, this review suggests that there is great potential for obtaining the lead drug from these species.

scholarly journals Evaluation of medicinal uses, phytochemistry and biological activities of Ehretia cymosa Thonn. (Ehretiaceae)

2021 ◽  
Vol 12 (2) ◽  
pp. 1521-1528
Author(s):  
Alfred Maroyi
Keyword(s):  
Respiratory Infections ◽  
Antioxidant Activities ◽  
Biological Activities ◽  
Medicinal Uses ◽  
Traditional Medicines ◽  
Plant Parts ◽  
Large Tree ◽  
Whole Plant ◽  
Phytochemical Compounds ◽  
Leaf Juice

Ehretia cymosa Thonn. is a deciduous medium-sized to large tree which occurs naturally from Sierra Leone in West Africa to Eritrea and Kenya in East Africa, and Zimbabwe in southern Africa. This study aims to provide a comprehensive review of medicinal uses, phytochemistry and biological activities of E. cymosa. This review examines the existing literature on the medicinal uses, phytochemistry and biological activities of E. cymosa. This study revealed that the bark, leaf juice, leaves, roots, seeds, stems, twigs and whole plant parts of E. cymosa are mainly used as aphrodisiac, laxative and ethnoveterinary medicines and as traditional medicines for gastro-intestinal problems, wounds, malaria, fever, typhoid, convulsions, epilepsy, toothache and respiratory infections. Phytochemical research revealed that the species is characterized by alkaloids, anthraquinones, essential oils, fatty acids, flavonoids, glycosides, phenolics, proanthocyanidins, pseudotannins, reducing sugars, saponins, steroids, tannins and terpenes. Ethnopharmacological research revealed that the extracts of E. cymosa and phytochemical compounds isolated from the species showed antibacterial, antidiabetic, antihyperglycaemic and antioxidant activities. Ehretia cymosa  should be subjected to detailed phytochemical, pharmacological and toxicological evaluations aimed at correlating its medicinal uses with its phytochemistry and pharmacological properties.

scholarly journals Important Flavonoids and Their Role as a Therapeutic Agent

Molecules ◽  
2020 ◽  
Vol 25 (22) ◽  
pp. 5243
Author(s):  
Asad Ullah ◽  
Sidra Munir ◽  
Syed Lal Badshah ◽  
Noreen Khan ◽  
Lubna Ghani ◽  
...  
Keyword(s):  
Animal Models ◽  
Human Health ◽  
Recent Work ◽  
Mode Of Action ◽  
Therapeutic Agent ◽  
Biological Activities ◽  
Cost Effective ◽  
Protective Effects ◽  
Potential Applications ◽  
Phytochemical Compounds

Flavonoids are phytochemical compounds present in many plants, fruits, vegetables, and leaves, with potential applications in medicinal chemistry. Flavonoids possess a number of medicinal benefits, including anticancer, antioxidant, anti-inflammatory, and antiviral properties. They also have neuroprotective and cardio-protective effects. These biological activities depend upon the type of flavonoid, its (possible) mode of action, and its bioavailability. These cost-effective medicinal components have significant biological activities, and their effectiveness has been proved for a variety of diseases. The most recent work is focused on their isolation, synthesis of their analogs, and their effects on human health using a variety of techniques and animal models. Thousands of flavonoids have been successfully isolated, and this number increases steadily. We have therefore made an effort to summarize the isolated flavonoids with useful activities in order to gain a better understanding of their effects on human health.

scholarly journals Prevailing Knowledge on the Bioavailability and Biological Activities of Sulphur Compounds from Alliums: A Potential Drug Candidate

Molecules ◽  
2020 ◽  
Vol 25 (18) ◽  
pp. 4111 ◽  
Author(s):  
Murugan Sesha Subramanian ◽  
Giri Nandagopal MS ◽  
Syafinaz Amin Nordin ◽  
Karuppiah Thilakavathy ◽  
Narcisse Joseph
Keyword(s):  
Allium Sativum ◽  
Therapeutic Agent ◽  
Biological Activities ◽  
Chemical Compounds ◽  
Water Soluble ◽  
Effective Dosage ◽  
Drug Candidate ◽  
Sulphur Compounds ◽  
Phytochemical Compounds ◽  
Derivatives Of

Allium sativum (garlic) is widely known and is consumed as a natural prophylactic worldwide. It produces more than 200 identified chemical compounds, with more than 20 different kinds of sulfide compounds. The sulfide compounds particularly are proven to contribute to its various biological roles and pharmacological properties such as antimicrobial, antithrombotic, hypoglycemic, antitumour, and hypolipidemic. Therefore, it is often referred as disease-preventive food. Sulphur-containing compounds from A. sativum are derivatives of S-alkenyl-l-cysteine sulfoxides, ajoene molecules, thiosulfinates, sulfides, and S-allylcysteine. This review presents an overview of the water-soluble and oil-soluble sulphur based phytochemical compounds present in garlic, highlighting their mechanism of action in treating various health conditions. However, its role as a therapeutic agent should be extensively studied as it depends on factors such as the effective dosage and the suitable method of preparation.

scholarly journals Isolation of 2,4-Di-tert-butylphenol and Butyrospermol 3-?-O-palmitate from Syzygium aqueum stem bark

2020 ◽  
Vol 5 (4) ◽  
Author(s):  
Alfinda Novi Kristanti ◽  
Ei Ei Aung ◽  
Nanik Siti Aminah ◽  
Yoshiaki Takaya ◽  
Rico Ramadhan
Keyword(s):  
Nuclear Magnetic Resonance ◽  
Magnetic Resonance ◽  
Traditional Medicine ◽  
Stem Bark ◽  
Tropical Regions ◽  
Chemical Substances ◽  
The World ◽  
Pure Compounds ◽  
Phytochemical Constituents ◽  
Column Chromatographic

Syzygium genus in Myrtaceae family is a rich source of phytochemical constituents that possess various bioactivities. One of well-known species of this genus, Syzygium aqueum, has been already utilized as traditional medicine. This plant is cultivated in countries of tropical regions of the world such as Malaysia and Indonesia. The aim of this study was intended to isolate phytochemical constituents from the stem bark of S. aqueum. To date, there have been no reports of chemical substances isolated from the stem bark of this plant. The powder of the stem bark was extracted followed by partitioned in order to obtain n-hexane extract which then was separated using silica gel column chromatographic several times until the pure compounds were resulted. The isolated compounds were identified by spectroscopie method including Fouirer Transform Infrared (FTIR) and nuclear magnetic resonance (NMR) and were known as 2,4-Di-tert-butylphenol & butyrospermol 3-β-O-palmitate, respectively. The spectoscopie data of those compounds were compared with references.

scholarly journals Analysis of Phytoconstituents and Biological Activities of Different Parts of Mahonia nepalensis and Berberis aristata

2017 ◽  
Vol 5 (1) ◽  
pp. 5-13 ◽  
Author(s):  
Rojeena Thusa ◽  
Sushika Mulmi
Keyword(s):  
Staphylococcus Aureus ◽  
Methanol Extract ◽  
Biological Activities ◽  
Authentic Sample ◽  
Uv Spectra ◽  
Phytochemical Screening ◽  
Zone Of Inhibition ◽  
Methanol Extracts ◽  
Pure Compounds ◽  
Different Parts

The phytochemicals and biological activities of extracts from leaves and stem of Mahonia nepalensis and Berberis aristata were carried out. Phytochemical screening showed the presence of alkaloids, steroids, polyphenols, quinones, glycoside, flavonoid, terpenoid and cardiac glycoside in the hexane, ethyl acetate and methanol extracts of leaf and stem of these two plants. The column chromatography of methanol extract of stem of Mahonia nepalensis resulted in isolation of four pure compounds MN1, MN2, MN3 and MN4. Out of four isolated compounds, two were identified as MN1:b- sitosterol and MN2: Berberine by comparison of melting point, Co-TLC, IR and UV spectra of authentic sample. Potent pharmacological activity of Mahonia nepalensis and Berberis aristata were revealed from antimicrobial activity and brine shrimp bioassay. Methanol extracts of stem of Mahonia nepalensis and Berberis aristata showed significant zone of inhibition of 18 mm and 21 mm respectively against the Staphylococcus aureus. Methanol extract of Berberis aristata were comparatively little stronger against Staphylococcus aureus than methanol extract of Mahonia nepalensis. LC50 values (μg/ml) of methanol extracts of stem of Berberis aristata and Mahonia nepalensis were found to be 8.058x10-4 and 8.3 whereas methanol extracts of leaf of Mahonia nepalensis and Berberis aristata were 389.04 and 1303.166 respectively.Nepal Journal of Biotechnology. Dec . 2 0 1 7 Vol. 5, No. 1: 5-13

scholarly journals Trado-Medical uses, Chemical Constituents and Biological Activities of Newbouldia laevis (Bignoniaceae): A Review

2021 ◽  
Author(s):  
Innocent U Okagu ◽  
Joseph C Ndefo ◽  
Matthias Onyebuchi Agbo
Keyword(s):  
Skin Diseases ◽  
Biological Activities ◽  
Chemical Constituents ◽  
Male Reproduction ◽  
Flowering Plant ◽  
Scientific Investigations ◽  
Health Promoting ◽  
Phytochemical Constituents ◽  
Ethnobotanical Uses ◽  
Different Parts

Newbouldia laevis (P. Beauv.) Seem. (Family, Bignoniaceae), commonly known as tree of life, is a purple-flowering plant that is widely distributed in many parts of Africa. Different parts of the plant, including the leaves, flower, stems and roots are prevalently used in African traditional medicine for the management of many diseases and conditions like diabetes, hypertension, skin diseases, ulcer, tumors, pains, infectious diseases, inflammation, dysentery, sickle cell disease and impotency. This review discusses the trado-medical uses, chemical constituents, and biological activities of N. laevis. Based on information generated from scientific investigations deposited in PubMed and SCOPUS, the chemical constituents of the plant include glycosides, anthraquinolones, volatile oils, tannins, steroids, alkaloids, flavonoids, terpenoids and sterols. Extracts different parts of the plant and compounds isolated from them have been reported to have several health-promoting potentials such as antioxidant, antimalarial, trypanocidal, antimicrobial, anthelmintic, analgesic, anti-inflammatory, antidiabetic, anti-arthritic, anti-thrombotic, cytoprotective, anti-hypertensive, central nervous system modulatory, male reproduction enhancing and oxytocic properties. These scientific investigations have led credence to the ethnobotanical uses of the plant in folkloric practice. In addition, the presence of phytochemical constituents in the plant might be responsible for the wide biological potentials.

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