scholarly journals Hydrogen-Bonded Organic–Inorganic Hybrid Based on Hexachloroplatinate and Nitrogen Heterocyclic Cations: Their Synthesis, Characterization, Crystal Structures, and Antitumor Activities In Vitro

Molecules ◽  
2018 ◽  
Vol 23 (6) ◽  
pp. 1397 ◽  
Author(s):  
Jin Zhao ◽  
Fuming Chen ◽  
Yutong Han ◽  
Huaqing Chen ◽  
Zhidong Luo ◽  
...  
Keyword(s):  
Crystal Structures ◽  
Antitumor Activities ◽  
Inorganic Hybrid ◽  
Heterocyclic Cations ◽  
Nitrogen Heterocyclic ◽  
Hydrogen Bonded

Synthesis, crystal structures and in vitro antitumor activities of some arylantimony derivatives of analogues of demethylcantharimide

2004 ◽  
Vol 689 (9) ◽  
pp. 1631-1638 ◽  
Author(s):  
Guo-Cang Wang ◽  
Jian Xiao ◽  
Lin Yu ◽  
Jin-Shan Li ◽  
Jing-Rong Cui ◽  
...  
Keyword(s):  
Crystal Structures ◽  
Antitumor Activities ◽  
Derivatives Of

Synthesis, crystal structures and in vitro antitumor activities of some organoantimony arylhydroxamates

2005 ◽  
Vol 690 (1) ◽  
pp. 151-156 ◽  
Author(s):  
Guo-Cang Wang ◽  
Yong-Na Lu ◽  
Jian Xiao ◽  
Lin Yu ◽  
Hai-Bin Song ◽  
...  
Keyword(s):  
Crystal Structures ◽  
Antitumor Activities

Synthesis and Antitumor Activity Evaluation of New Phenanthrene-Based Tylophorine Derivatives

2019 ◽  
Vol 16 (6) ◽  
pp. 462-467
Author(s):  
Songtao Li ◽  
Hongling Zhao ◽  
Zhifeng Yin ◽  
Shuhua Deng ◽  
Yang Gao ◽  
...  
Keyword(s):  
Antitumor Activity ◽  
Cell Lines ◽  
Antitumor Activities ◽  
Human Carcinoma ◽  
Carcinoma Cell Lines ◽  
Structure Activity ◽  
Human Carcinoma Cell ◽  
Ic50 Values ◽  
Relationship Of

A series of new phenanthrene-based tylophorine derivatives (PBTs) were synthesized in good yield and their structures were characterized by 1H-NMR spectroscopy and ESI MS. In vitro antitumor activity of these compounds against five human carcinoma cell lines, including HCT116 (colorectal), BGC-823 (gastric), HepG-2 (hepatic), Hela (cervical) and H460 (lung) cells, was evaluated by MTT assay. Among these PBTs, compound 6b showed the highest antitumor activities against HCT116 and HepG-2 cell lines with IC50 values of 6.1 and 6.4 μM, respectively, which were comparable to that of adriamycin hydrochloride. The structure-activity relationship of these compounds was also discussed based on the results of their antitumor activity.

Crystal Structures and Magnetic Properties of Hydrogen-Bonded Nitronyl Nitroxide Radicals and Their Metal Complexes

2002 ◽  
Vol 379 (1) ◽  
pp. 153-158 ◽  
Author(s):  
Mikio Ueda ◽  
Tomoyuki Mochida ◽  
Sachie Furukawa ◽  
Hideaki Suzuki ◽  
Hirosi Moriyama ◽  
...  
Keyword(s):  
Magnetic Properties ◽  
Metal Complexes ◽  
Crystal Structures ◽  
Nitronyl Nitroxide ◽  
Nitroxide Radicals ◽  
Hydrogen Bonded
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