scholarly journals Using Peptidomimetics and Constrained Peptides as Valuable Tools for Inhibiting Protein–Protein Interactions

Molecules ◽  
2018 ◽  
Vol 23 (4) ◽  
pp. 959 ◽  
Author(s):  
Naomi Robertson ◽  
David Spring
Keyword(s):  
Protein Interactions ◽  
Protein Protein Interactions ◽  
Constrained Peptides ◽  
Inhibiting Protein

CHAPTER 8. Double-click Stapled Peptides for Inhibiting Protein–Protein Interactions

2017 ◽  
pp. 164-187 ◽  
Author(s):  
K. Sharma ◽  
D. L. Kunciw ◽  
W. Xu ◽  
M. M. Wiedmann ◽  
Y. Wu ◽  
...  
Keyword(s):  
Protein Interactions ◽  
Protein Protein Interactions ◽  
Stapled Peptides ◽  
Inhibiting Protein

Inhibiting Protein−Protein Interactions:  A Model for Antagonist Design

Biochemistry ◽  
2000 ◽  
Vol 39 (24) ◽  
pp. 7092-7099 ◽  
Author(s):  
Boris A. Chrunyk ◽  
Michele H. Rosner ◽  
Yang Cong ◽  
Alexander S. McColl ◽  
Ivan G. Otterness ◽  
...  
Keyword(s):  
Protein Interactions ◽  
Protein Protein Interactions ◽  
Inhibiting Protein

scholarly journals Multivalent Cluster Nanomolecules for Inhibiting Protein–Protein Interactions

2019 ◽  
Vol 30 (10) ◽  
pp. 2594-2603 ◽  
Author(s):  
Elaine A. Qian ◽  
Yanxiao Han ◽  
Marco S. Messina ◽  
Heather D. Maynard ◽  
Petr Král ◽  
...  
Keyword(s):  
Protein Interactions ◽  
Protein Protein Interactions ◽  
Inhibiting Protein

scholarly journals Constrained Peptides as Miniature Protein Structures

2012 ◽  
Vol 2012 ◽  
pp. 1-15 ◽  
Author(s):  
Hang Yin
Keyword(s):  
Protein Engineering ◽  
Protein Interactions ◽  
Protein Structures ◽  
Secondary Structures ◽  
Biological Functions ◽  
Protein Protein Interactions ◽  
Protein Secondary Structures ◽  
Recent Developments ◽  
Noncovalent Bonds ◽  
Constrained Peptides

This paper discusses the recent developments of protein engineering using both covalent and noncovalent bonds to constrain peptides, forcing them into designed protein secondary structures. These constrained peptides subsequently can be used as peptidomimetics for biological functions such as regulations of protein-protein interactions.

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