Synthesis, Anti-Proliferative Activity Evaluation and 3D-QSAR Study of Naphthoquinone Derivatives as Potential Anti-Colorectal Cancer Agents

Julio Acuña; Jhoan Piermattey; Daneiva Caro; Sven Bannwitz; Luis Barrios; Jairo López; Yanet Ocampo; Ricardo Vivas-Reyes; Fabio Aristizábal; Ricardo Gaitán; Klaus Müller; Luis Franco

doi:10.3390/molecules23010186

Synthesis, Anti-Proliferative Activity Evaluation and 3D-QSAR Study of Naphthoquinone Derivatives as Potential Anti-Colorectal Cancer Agents

Molecules ◽

10.3390/molecules23010186 ◽

2018 ◽

Vol 23 (1) ◽

pp. 186 ◽

Cited By ~ 3

Author(s):

Julio Acuña ◽

Jhoan Piermattey ◽

Daneiva Caro ◽

Sven Bannwitz ◽

Luis Barrios ◽

...

Keyword(s):

Colorectal Cancer ◽

Proliferative Activity ◽

3D Qsar ◽

Qsar Study ◽

Activity Evaluation

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Antimycobacterial activity evaluation, time-kill kinetic and 3D-QSAR study of C-(3-aminomethyl-cyclohexyl)-methylamine derivatives

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2012.12.083 ◽

2013 ◽

Vol 23 (5) ◽

pp. 1365-1369 ◽

Cited By ~ 13

Author(s):

Deepak Kumar ◽

K. Kranthi Raj ◽

MaiAnn Bailey ◽

Torey Alling ◽

Tanya Parish ◽

...

Keyword(s):

3D Qsar ◽

Antimycobacterial Activity ◽

Qsar Study ◽

Activity Evaluation ◽

Evaluation Time ◽

Time Kill

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Synthesis, activity evaluation and 3D-QSAR study of some novel derivatives of 4, 5, 6, 7-tetrahydrothieno [3,2-c] pyridine

Chinese Chemical Letters ◽

10.1016/j.cclet.2008.06.008 ◽

2008 ◽

Vol 19 (9) ◽

pp. 1075-1079

Author(s):

Die Cheng ◽

Deng Ke Liu ◽

Mo Liu ◽

Ying Liu ◽

Wei Ren Xu ◽

...

Keyword(s):

3D Qsar ◽

Qsar Study ◽

Activity Evaluation ◽

Synthesis Activity ◽

Derivatives Of

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3D-QSAR Study on Ring Substituted Imidazoles for Their Antitubercular Activity

Letters in Drug Design & Discovery ◽

10.2174/157018010790225912 ◽

2010 ◽

Vol 7 (2) ◽

pp. 128-132 ◽

Cited By ~ 1

Author(s):

Gyanendra Sharma ◽

Devender Pathak

Keyword(s):

3D Qsar ◽

Antitubercular Activity ◽

Qsar Study

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A 3D-QSAR Study on a Series of Benzimidazole Derivatives Acting as Hepatitis C Virus Inhibitors: Application of kNN-Molecular Field Analysis

Medicinal Chemistry ◽

10.2174/157340610791321460 ◽

2010 ◽

Vol 6 (2) ◽

pp. 87-90 ◽

Cited By ~ 2

Author(s):

S.P. Gupta ◽

S. Samanta ◽

Vaishali M. Patil

Keyword(s):

Hepatitis C Virus ◽

Hepatitis C ◽

3D Qsar ◽

Field Analysis ◽

Molecular Field ◽

Benzimidazole Derivatives ◽

Qsar Study ◽

Molecular Field Analysis

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A 3D-QSAR Study on Betulinic Acid Derivatives as Anti-Tumor Agents and the Synthesis of Novel Derivatives for Modeling Validation

Anti-Cancer Agents in Medicinal Chemistry ◽

10.2174/1871520616666160922101712 ◽

2017 ◽

Vol 17 (4) ◽

pp. 566-575 ◽

Cited By ~ 3

Author(s):

Weimin Ding ◽

Sheng Zhang ◽

Meixuan Zhu ◽

Shaoming Wang ◽

Tao Xu ◽

...

Keyword(s):

Betulinic Acid ◽

3D Qsar ◽

Qsar Study

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Synthesis and anti-proliferative activity evaluation of N3-acyl-N5-aryl-3,5-diaminoindazole analogues as anti-head and neck cancer agent

DARU Journal of Pharmaceutical Sciences ◽

10.1186/2008-2231-22-4 ◽

2014 ◽

Vol 22 (1) ◽

Cited By ~ 1

Author(s):

Jinho Lee ◽

Jina Kim ◽

Victor Sukbong Hong ◽

Jong-Wook Park

Keyword(s):

Head And Neck Cancer ◽

Head And Neck ◽

Neck Cancer ◽

Proliferative Activity ◽

Activity Evaluation ◽

Cancer Agent

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3D-QSAR Study on Apicidin Inhibit Histone Deacetylase

Chinese Journal of Chemistry ◽

10.1002/cjoc.20030211216 ◽

2010 ◽

Vol 21 (12) ◽

pp. 1596-1607 ◽

Cited By ~ 4

Author(s):

Hai-Feng Chen ◽

Jiu-Hong Kang ◽

Qiang Li ◽

Bao-Shan Zeng ◽

Xiao-Jun Yao ◽

...

Keyword(s):

Histone Deacetylase ◽

3D Qsar ◽

Qsar Study

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Design, synthesis and docking-based 3D-QSAR study of novel 2-substituted 2-aminopropane-1,3-diols as potent and selective agonists of sphingosine-1-phosphate 1 (S1P1) receptor

MedChemComm ◽

10.1039/c3md00079f ◽

2013 ◽

Vol 4 (9) ◽

pp. 1267 ◽

Cited By ~ 16

Author(s):

Yulin Tian ◽

Jing Jin ◽

Xiaojian Wang ◽

Weijuan Han ◽

Gang Li ◽

...

Keyword(s):

3D Qsar ◽

Qsar Study ◽

Design Synthesis ◽

S1p1 Receptor ◽

Sphingosine 1 Phosphate ◽

Selective Agonists

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3D-QSAR study of adamantyl N-benzylbenzamides as melanogenesis inhibitors

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2013.11.056 ◽

2014 ◽

Vol 24 (2) ◽

pp. 667-673 ◽

Cited By ~ 5

Author(s):

Yong Deog Hong ◽

Heung Soo Baek ◽

Haelim Cho ◽

Soo Mi Ahn ◽

Ho Sik Rho ◽

...

Keyword(s):

3D Qsar ◽

Qsar Study

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Anti-proliferative Activity of Ethanol Extracts of Root of Aralia cordata var. continentalis through Proteasomal Degradation of Cyclin D1 in Human Colorectal Cancer Cells

Korean Journal of Medicinal Crop Science ◽

10.7783/kjmcs.2017.25.5.328 ◽

2017 ◽

Vol 25 (5) ◽

pp. 328-334

Author(s):

Su Bin Park ◽

Gwang Hun Park ◽

Hun Min Song ◽

Ji Hye Park ◽

Myeong Su Shin ◽

...

Keyword(s):

Colorectal Cancer ◽

Cyclin D1 ◽

Cancer Cells ◽

Proliferative Activity ◽

Proteasomal Degradation ◽

Human Colorectal Cancer ◽

Aralia Cordata ◽

Colorectal Cancer Cells ◽

Ethanol Extracts ◽

Human Colorectal Cancer Cells

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