scholarly journals Chemical Composition of Pinus roxburghii Bark Volatile Oil and Validation of Its Anti-Inflammatory Activity Using Molecular Modelling and Bleomycin-Induced Inflammation in Albino Mice

Molecules ◽  
2017 ◽  
Vol 22 (9) ◽  
pp. 1384 ◽  
Author(s):  
Rola Labib ◽  
Fadia Youssef ◽  
Mohamed Ashour ◽  
Mohamed Abdel-Daim ◽  
Samir Ross
Author(s):  
Michelyn Haroun ◽  
Christopher Tratrat ◽  
Evangelia Tsolaki ◽  
Anthi Petrou ◽  
Antonis Gavalas ◽  
...  

Background.: Inflammation is a multifactorial process reflecting response of the organismto various stimuli and is associated to a number of disorders such as arthritis, asthma and psoriasis, which require long-lasting or repeated treat-ment. Objective.: The aim of this paper is to evaluate the anti-inflammatory activity of previous synthesized thiazole-based chal-cone derivatives. Method.: Chalcones were synthesized via Cliazen-Schmidt condensation1-(4-methyl-2-alkylamino)thiazol-5-yl) ethanone with corresponding aromatic aldehyde. For the evaluation of possible anti-inflammatory activity carrageneen mouse paw edema was used. Results.: Eight out of thirteen tested chalcones showed anti-inflammatory activity in range of 51-55%. Prediction of toxicity revealed that these compounds are not toxic. Conclusion.: In general, it can be concluded that these compounds can be used for further modifications in order to develop more active and safe agents.


Química Nova ◽  
2015 ◽  
Author(s):  
Amira Arciniegas ◽  
Ana L. Pérez-Castorena ◽  
Antonio Nieto-Camacho ◽  
Jhon Ironzi Maldonado ◽  
José Luis Villaseñor ◽  
...  

2011 ◽  
Vol 124 (1) ◽  
pp. 309-315 ◽  
Author(s):  
Sergey V. Popov ◽  
Raisa G. Ovodova ◽  
Victoria V. Golovchenko ◽  
Galina Yu. Popova ◽  
Feodor V. Viatyasev ◽  
...  

Author(s):  
Jacob Jesurun RS ◽  
Senthilkumaran Jagadeesh ◽  
Somasundaram Ganesan ◽  
Venugopala Rao K ◽  
Madhavi Eerike

2017 ◽  
Vol 22 (2) ◽  
pp. 111 ◽  
Author(s):  
Fitriah Ardiawijianti Iriani ◽  
Nining Sugihartini ◽  
Tedjo Yuwono

Essential oil of clove (Syzygium aromaticum) containing eugenol has an anti-inflammatory activity. The study was aimed to develop the formulation of lotion by adding of oleic acid and propylene glycol as penetration enhancer. The effect of enhancer composition was also studied. Lotion was prepared with the composition of oleic acid (AO) and propylene glycol (PG) as follow: 1:0 (FI), 0,5:0,5 (FII), 0:1 (FIII). Capacity an anti-inflammatory of formulation based on parameters of the amount of cells with COX-2 expression, the number of inflammatory cells and the epidermis thickness was evaluated using male mouse strain BALb/C induced by crotton oil as inflammatory agents. The results showed that the increasing composition propylene glycol caused the decreasing of the amount of cells with COX-2 expression (p <0.05), the inflammatory cells (P <0.05) and the epidermis thickness (p <0.05)


2020 ◽  
Vol 8 (6) ◽  
pp. 226-232
Author(s):  
Abdoulaye Thiam ◽  
Momar Talla Gueye ◽  
Cheikhna Hamala Sanghare ◽  
El Hadji Barka Ndiaye ◽  
Serigne Mbacké Diop ◽  
...  

2001 ◽  
Vol 12 (3) ◽  
pp. 354-359 ◽  
Author(s):  
Antonio C. Siani ◽  
Ana M. P. Silva ◽  
Marcos J. Nakamura ◽  
Márcia V. De Carvalho ◽  
Maria G. M. O. Henriques ◽  
...  

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