scholarly journals Synthesis, Antitumor Evaluation and Molecular Docking of New Morpholine Based Heterocycles

Molecules ◽  
2017 ◽  
Vol 22 (7) ◽  
pp. 1211 ◽  
Author(s):  
Zeinab Muhammad ◽  
Mastoura Edrees ◽  
Rasha Faty ◽  
Sobhi Gomha ◽  
Seham Alterary ◽  
...  
Keyword(s):  
Molecular Docking ◽  
Antitumor Evaluation

Synthesis, single-crystal, in vitro antitumor evaluation and molecular docking of 3-substitued 5,5-diphenylimidazolidine-2,4-dione derivatives

2013 ◽  
Vol 22 (12) ◽  
pp. 6129-6142 ◽  
Author(s):  
Amer M. Alanazi ◽  
Adel S. El-Azab ◽  
Ibrahim A. Al-Swaidan ◽  
Azza R. Maarouf ◽  
Eman R. El-Bendary ◽  
...  
Keyword(s):  
Molecular Docking ◽  
Single Crystal ◽  
Antitumor Evaluation

Synthesis, structure prediction, pharmacokinetic properties, molecular docking and antitumor activities of some novel thiazinone derivatives

2015 ◽  
Vol 39 (9) ◽  
pp. 7120-7129 ◽  
Author(s):  
Selvam Athavan Alias Anand ◽  
Chandrasekaran Loganathan ◽  
Nisha Susan Thomas ◽  
Kuppusamy Saravanan ◽  
Antony Therasa Alphonsa ◽  
...  
Keyword(s):  
Molecular Docking ◽  
Structure Prediction ◽  
Antitumor Activities ◽  
Convenient Synthesis ◽  
Pharmacokinetic Properties ◽  
Antitumor Evaluation

Convenient synthesis of [1,3]thiazin-4-ones by the unprecedented cyclization of acetylene diesters with 3-alkyl-2,6-diarylpiperidin-4-one thiosemicarbazone derivatives and their antitumor evaluation.

Synthesis, antitumor evaluation, and molecular docking studies of indole–indazolyl hydrazide–hydrazone derivatives

2016 ◽  
Vol 148 (2) ◽  
pp. 305-314 ◽  
Author(s):  
Reddymasu Sreenivasulu ◽  
Pombala Sujitha ◽  
Surender Singh Jadav ◽  
Mohamed Jawed Ahsan ◽  
C. Ganesh Kumar ◽  
...  
Keyword(s):  
Molecular Docking ◽  
Docking Studies ◽  
Molecular Docking Studies ◽  
Antitumor Evaluation

Antitumor evaluation and molecular docking study of substituted 2-benzylidenebutane-1,3-dione, 2-hydrazonobutane-1,3-dione and trifluoromethyl-1H-pyrazole analogues

2014 ◽  
Vol 30 (4) ◽  
pp. 679-687 ◽  
Author(s):  
Ibrahim A. Al-Suwaidan ◽  
Naglaa I. Abdel-Aziz ◽  
Adel S. El-Azab ◽  
Magda A.-A. El-Sayed ◽  
Amer M. Alanazi ◽  
...  
Keyword(s):  
Molecular Docking ◽  
Docking Study ◽  
Molecular Docking Study ◽  
Antitumor Evaluation

scholarly journals Synthesis, Molecular Docking, And Antitumor Evaluation of Some New Pyrazole, Pyridine, And Thiazole Derivatives Incorporating Sulfonamide Residue

2021 ◽  
Author(s):  
Sameh Elgogary ◽  
Ibrahim Radini
Keyword(s):  
Breast Cancer ◽  
Molecular Docking ◽  
Cell Line ◽  
Cancer Cell ◽  
Cancer Cell Line ◽  
Thiazole Derivatives ◽  
Standard Drug ◽  
Ic50 Values ◽  
Antitumor Evaluation ◽  
Mcf 7

Abstract Cancer is the second leading cause of death worldwide. There is always a huge demand for novel anticancer. New series of pyrazole, pyridine, thiazole derivatives containing sulfonamide moiety were prepared and screened for their antitumor activity against breast cancer cell line (MCF-7). The results of this investigation revealed that compounds 3 and 8 had significant anticancer activity against the MCF-7 cancer cell line with IC50 values 19.2 and 14.2 μM, respectively, in relation to the standard drug, doxorubicin.

Synthesis, antitumor evaluation and molecular docking studies of [1,2,4]triazolo[4,3- b ][1,2,4,5]tetrazine derivatives

2016 ◽  
Vol 26 (13) ◽  
pp. 3042-3047 ◽  
Author(s):  
Feng Xu ◽  
Zhen-zhen Yang ◽  
Jun-rong Jiang ◽  
Wan-gui Pan ◽  
Xiao-le Yang ◽  
...  
Keyword(s):  
Molecular Docking ◽  
Docking Studies ◽  
Molecular Docking Studies ◽  
Antitumor Evaluation

Design, synthesis, antitumor evaluation, 3D-QSAR and molecular docking studies of novel 4-aminoacridone compounds

2017 ◽  
Vol 26 (10) ◽  
pp. 2538-2546 ◽  
Author(s):  
Lin Tian ◽  
Chang J. Feng ◽  
Tong X. Li ◽  
Zhao Li ◽  
Wei H. Yang ◽  
...  
Keyword(s):  
Molecular Docking ◽  
3D Qsar ◽  
Docking Studies ◽  
Design Synthesis ◽  
Molecular Docking Studies ◽  
Antitumor Evaluation

Synthesis, antitumor evaluation and molecular docking study of a novel podophyllotoxin-lonidamine hybrid

2018 ◽  
Vol 27 (10) ◽  
pp. 2231-2238 ◽  
Author(s):  
Lei Zhang ◽  
Jie Zheng ◽  
Ying Rong ◽  
Chengli Yang ◽  
Li Long ◽  
...  
Keyword(s):  
Molecular Docking ◽  
Docking Study ◽  
Molecular Docking Study ◽  
Antitumor Evaluation

EVALUATION OF IN-SILICO ANTICANCER POTENTIAL OF PYRETHROIDS: A COMPARATIVE MOLECULAR DOCKING STUDY

2015 ◽  
Author(s):  
Manik Ghosh ◽  
Kamal Kant ◽  
Anoop Kumar ◽  
Padma Behera ◽  
Naresh Rangra ◽  
...  
Keyword(s):  
Molecular Docking ◽  
In Silico ◽  
Docking Study ◽  
Molecular Docking Study
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