scholarly journals Influence of Pyranose and Spacer Arm Structures on Phloem Mobility and Insecticidal Activity of New Tralopyril Derivatives

Molecules ◽  
2017 ◽  
Vol 22 (7) ◽  
pp. 1058 ◽  
Author(s):  
Yao Chen ◽  
Zhi Lei ◽  
Ying Zhang ◽  
Wen Yang ◽  
Hui Liu ◽  
...  
Keyword(s):  
Insecticidal Activity ◽  
Spacer Arm ◽  
Phloem Mobility

scholarly journals Vectorisation of agrochemicals via amino acid carriers: influence of the spacer arm structure on the phloem mobility of phenylpyrrole conjugates in theRicinussystem

2017 ◽  
Vol 73 (9) ◽  
pp. 1972-1982 ◽  
Author(s):  
Sophie Marhadour ◽  
Hanxiang Wu ◽  
Wen Yang ◽  
Cécile Marivingt-Mounir ◽  
Jean-Louis Bonnemain ◽  
...  
Keyword(s):  
Amino Acid ◽  
Spacer Arm ◽  
Phloem Mobility

scholarly journals Vectorizing Pro-Insecticide: Influence of Linker Length on Insecticidal Activity and Phloem Mobility of New Tralopyril Derivatives

Molecules ◽  
2021 ◽  
Vol 26 (15) ◽  
pp. 4570
Author(s):  
Tian Xing Li ◽  
Yao Chen ◽  
Hui Fang Liu ◽  
Chi Yu Ma ◽  
Wen Yang
Keyword(s):  
Amino Acid ◽  
Glutamic Acid ◽  
Insecticidal Activity ◽  
Parent Compound ◽  
In Vivo Metabolism ◽  
Straight Chain ◽  
Phloem Sap ◽  
The Third ◽  
Phloem Mobility

To improve the proinsecticidal activity and phloem mobility of amino acid–tralopyril conjugates further, nine conjugates were designed and synthesized by introducing glutamic acid to tralopyril, and the length of the linker between glutamic acid and tralopyril ranged from 2 atoms to 10 atoms. The results of insecticidal activity against the third-instar larvae of P. xylostella showed that conjugates 42, 43, 44, and 45 (straight-chain containing 2–5 atoms) exhibited good insecticidal activity, and their LC50 values were 0.2397 ± 0.0366, 0.4413 ± 0.0647, 0.4400 ± 0.0624, and 0.4602 ± 0.0655 mM, respectively. The concentrations of conjugates 43–45 were higher than that of conjugate 42 in the phloem sap at 2 h, and conjugate 43 showed the highest concentration. The introduction of glutamic acid can improve phloem mobility. The in vivo metabolism of conjugates 42 and 43 was investigated in P. xylostella, and the parent compound tralopyril was detected at concentrations of 0.5950 and 0.3172 nmol/kg, respectively. According to the above results, conjugates 42 and 43 were potential phloem mobile pro-insecticide candidates.

A new derivative of fipronil: Effect of adding a glycinyl group to the 5-amine of pyrazole on phloem mobility and insecticidal activity

2009 ◽  
Vol 95 (3) ◽  
pp. 126-130 ◽  
Author(s):  
Ding-Xin Jiang ◽  
Xue-Lin Lu ◽  
Shan Hu ◽  
Xiao-Bing Zhang ◽  
Han-Hong Xu
Keyword(s):  
Insecticidal Activity ◽  
Phloem Mobility

Insecticidal activity of acetamiprid in different forms

2020 ◽  
pp. 54-60
Author(s):  
Marina Nikolaevna Kostina ◽  
◽  
Filipp Nikolaevich Kostin ◽  
Keyword(s):  
Insecticidal Activity

Characteristics and Function of the Chitin Binding Protein from Xenorhabdus nematophila

2019 ◽  
Vol 26 (6) ◽  
pp. 414-422
Author(s):  
Jia Liu ◽  
Ping Song ◽  
Jie Zhang ◽  
Ziyan Nangong ◽  
Xiaobei Liu ◽  
...  
Keyword(s):  
Antifungal Activity ◽  
Growth Inhibition ◽  
Insecticidal Activity ◽  
Spore Germination ◽  
Binding Protein ◽  
Colloidal Chitin ◽  
Inhibition Rate ◽  
Xenorhabdus Nematophila ◽  
Chitin Binding Protein ◽  
And Function

Background: Genome sequence analysis (GenBank access No.: FN667742.1) shows that Xenorhabdus nematophila ATCC19061 contains one gene (Xn-cbp) encoding chitin binding protein (Xn-CBP). Objective: The present work aims to clarify the characteristics and function of Xn-CBP from X. nematophila HB310. Methods: In this study, the Xn-cbp gene was cloned and expressed in Escherichia coli BL21 (DE3). Substrate binding assays were performed to explain the ability of Xn-CBP combined with the polysaccharide. The insecticidal toxicity of Xn-CBP against the second-instar larvae of Helicoverpa armigera was determined by feeding method. Besides, the antifungal activity of Xn-CBP against Coniothyrium diplodiella, Verticillium dahlia, and Fusarium oxysporum was tested by spore germination assay and hyphal extension assay. Results: Xn-CBP encoded 199 amino acids with a calculated mass of 28 kDa, which contained a signal peptide and a chitin binding domain. The Bmax and Kd values of Xn-CBP to colloidal chitin were 2.46 and 4.08, respectively. Xn-CBP had insecticidal activity against the H. armigera with a growth inhibition rate of 84.08%. Xn-CBP had the highest spore germination inhibitory effect on C. diplodiella with the inhibition rate of 83.11%. The hyphal growth inhibition rate of Xn-CBP to F. oxysporum, 41.52%, was higher than the other two fungi. Conclusion: The Xn-CBP had the highest binding ability to colloidal chitin and it showed insecticidal activity and antifungal activity. The present study laid a foundation for further exploitation and utilization of X. nematophila.

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