scholarly journals Special Issue “Structure–Activity Relationship of Natural Products”

Molecules ◽  
2017 ◽  
Vol 22 (5) ◽  
pp. 697
Author(s):  
Jean-Marc Sabatier
Keyword(s):  
Natural Products ◽  
Structure Activity Relationship ◽  
Activity Relationship ◽  
Special Issue ◽  
Structure Activity ◽  
Relationship Of

scholarly journals Structure–Activity Relationship of Cytotoxic Natural Products from Indonesian Marine Sponges

2022 ◽  
Author(s):  
Jonathan A. Panggabean ◽  
Sya’ban P. Adiguna ◽  
Tutik Murniasih ◽  
Siti I. Rahmawati ◽  
Asep Bayu ◽  
...  
Keyword(s):  
Natural Products ◽  
Structure Activity Relationship ◽  
Marine Sponges ◽  
Activity Relationship ◽  
Structure Activity ◽  
Relationship Of

Chemistry and Structure−Activity Relationship of HIV-1 Integrase Inhibitor Integracide B and Related Natural Products

2003 ◽  
Vol 66 (10) ◽  
pp. 1338-1344 ◽  
Author(s):  
Sheo B. Singh ◽  
John G. Ondeyka ◽  
William A. Schleif ◽  
Peter Felock ◽  
Daria J. Hazuda
Keyword(s):  
Natural Products ◽  
Integrase Inhibitor ◽  
Structure Activity Relationship ◽  
Activity Relationship ◽  
Structure Activity ◽  
Relationship Of ◽  
Hiv 1

scholarly journals Establishment of a Phenotypic-based Sand Dollar Fellaster zelandiae Embryo Development Assay and its Application in Defining the Structure-Activity Relationship of Discorhabdin Alkaloids

2013 ◽  
Vol 8 (6) ◽  
pp. 1934578X1300800
Author(s):  
Tanja Grkovic ◽  
Brent R. Copp
Keyword(s):  
Natural Products ◽  
New Zealand ◽  
Embryo Development ◽  
Structure Activity Relationship ◽  
Structural Features ◽  
Activity Relationship ◽  
Sand Dollar ◽  
Structure Activity ◽  
The Common ◽  
Relationship Of

An embryo development assay using the common New Zealand intertidal species Fellaster zelandiae (sand dollar) is presented. The assay was validated by comparing activity profiles of a range of discorhabdin alkaloids, natural products sourced from Latrunculia spp. sponges containing a core pyrido[2,3- h]pyrrolo[4,3,2- de]quinoline tetracyclic skeleton bound to various spiro-substituents at the C-6 position. Structural features on the discorhabdin molecule that correlated to the greatest degree of F. zelandiae embryo developmental inhibition were the presence of a spiro-dienone moiety and a C-2 bromine substituent. Based on the sand dollar embryo development assay results, a mechanism for the activity of the discorhabdin alkaloids is proposed.

Structure-activity relationship of (-) mammea A/BB derivatives against Leishmania amazonensis

Planta Medica ◽  
2008 ◽  
Vol 74 (09) ◽  
Author(s):  
MA Brenzan ◽  
CV Nakamura ◽  
BPD Filho ◽  
T Ueda-Nakamura ◽  
MCM Young ◽  
...  
Keyword(s):  
Structure Activity Relationship ◽  
Leishmania Amazonensis ◽  
Activity Relationship ◽  
Structure Activity ◽  
Relationship Of
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