scholarly journals Microbial Glycosylation of Daidzein, Genistein and Biochanin A: Two New Glucosides of Biochanin A

Molecules ◽  
2017 ◽  
Vol 22 (1) ◽  
pp. 81 ◽  
Author(s):  
Sandra Sordon ◽  
Jarosław Popłoński ◽  
Tomasz Tronina ◽  
Ewa Huszcza
Keyword(s):  
Biochanin A ◽  
Microbial Glycosylation

Selective antimicrobial activity of biochanin A

Planta Medica ◽  
2009 ◽  
Vol 75 (09) ◽  
Author(s):  
J Flesar ◽  
O Sklenickova ◽  
E Vlkova ◽  
J Malik ◽  
L Kokoska
Keyword(s):  
Antimicrobial Activity ◽  
Biochanin A ◽  
Selective Antimicrobial Activity

Therapeutic Potential of Biochanin-A Against Isoproterenol-Induced Myocardial Infarction in Rats

2020 ◽  
Vol 18 (1) ◽  
pp. 31-36 ◽  
Author(s):  
Sangeethadevi Govindasami ◽  
Veera Venkata Sathibabu Uddandrao ◽  
Nivedha Raveendran ◽  
Vadivukkarasi Sasikumar
Keyword(s):  
Myocardial Infarction ◽  
Antioxidant Enzymes ◽  
Therapeutic Potential ◽  
Biochanin A ◽  
Glutathione S Transferase ◽  
Serum Glutamic Oxaloacetic Transaminase ◽  
Creatine Kinase Mb ◽  
Male Wistar Rats ◽  
Detoxifying Enzyme ◽  
Cardioprotective Effects

Background: This study determined the effect of Biochanin A (BCA) on isoproterenol (ISO) induced Myocardial Infarction (MI) in male Wistar rats. Methods: Animals (weighing 150-180 g) were divided into four groups, with six animals in each group and pretreated with BCA (10mg/kg Body Weight [BW]) and ɑ-tocopherol (60mg/kg BW) for 30 days; and ISO (20mg/kg BW) was administrated subcutaneously on the 31st and 32nd day. Results: ISO-induced MI rats demonstrated the significant elevation of serum glutamic oxaloacetic transaminase, serum glutamic pyruvic transaminase, lactate dehydrogenase, creatine kinase-MB and cardiac troponin; however, concomitant pretreatment with BCA protected the rats from cardiotoxicity caused by ISO. Activities of antioxidant enzymes, such as superoxide dismutase, catalase, glutathione peroxidase, glutathione-S-transferase and glutathione reductase significantly reduced in the heart with ISO-induced MI. Pretreatment with BCA produced a marked reversal of these antioxidant enzymes related to MI-induced by ISO. Conclusion: In conclusion, this study suggested that BCA exerts cardioprotective effects through modulating lipid peroxidation, enhancing antioxidants, and detoxifying enzyme systems.

Attenuation of lipid metabolic abnormalities, proinflammatory cytokines, and matrix metalloproteinase expression by biochanin-A in isoproterenol-induced myocardial infarction in rats

2021 ◽  
pp. 1-12
Author(s):  
Govindasami Sangeethadevi ◽  
Sathibabu Uddandrao V. V. ◽  
Rani Antony Rathinasamy Jansy Isabella ◽  
Ganapathy Saravanan ◽  
Ponnusamy Ponmurugan ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Matrix Metalloproteinase ◽  
Proinflammatory Cytokines ◽  
Biochanin A ◽  
Metabolic Abnormalities

Mechanisms of the growth inhibitory effects of the isoflavonoid biochanin A on LNCaP cells and xenografts

The Prostate ◽  
2002 ◽  
Vol 52 (3) ◽  
pp. 201-212 ◽  
Author(s):  
Lori Rice ◽  
Von G. Samedi ◽  
Theresa A. Medrano ◽  
Carol A. Sweeney ◽  
Henry V. Baker ◽  
...  
Keyword(s):  
Biochanin A ◽  
Lncap Cells ◽  
Inhibitory Effects ◽  
Growth Inhibitory
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