scholarly journals Compound Library Screening Identified Cardiac Glycoside Digitoxin as an Effective Growth Inhibitor of Gefitinib-Resistant Non-Small Cell Lung Cancer via Downregulation of α-Tubulin and Inhibition of Microtubule Formation

Molecules ◽  
2016 ◽  
Vol 21 (3) ◽  
pp. 374 ◽  
Author(s):  
Yi-Ze Zhang ◽  
Xi Chen ◽  
Xing-Xing Fan ◽  
Jian-Xing He ◽  
Jun Huang ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Cardiac Glycoside ◽  
Growth Inhibitor ◽  
Small Cell ◽  
Library Screening ◽  
Compound Library ◽  
Small Cell Lung ◽  
Microtubule Formation ◽  
Effective Growth

scholarly journals Effective growth-suppressive activity of maternal embryonic leucine-zipper kinase (MELK) inhibitor against small cell lung cancer

Oncotarget ◽  
2016 ◽  
Vol 7 (12) ◽  
pp. 13621-13633 ◽  
Author(s):  
Hiroyuki Inoue ◽  
Taigo Kato ◽  
Sope Olugbile ◽  
Kenji Tamura ◽  
Suyoun Chung ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Leucine Zipper ◽  
Small Cell ◽  
Suppressive Activity ◽  
Small Cell Lung ◽  
Effective Growth

Cardiac glycoside ouabain induces autophagic cell death in non-small cell lung cancer cells via a JNK-dependent decrease of Bcl-2

2014 ◽  
Vol 89 (2) ◽  
pp. 197-209 ◽  
Author(s):  
Annalisa Trenti ◽  
Paolo Grumati ◽  
Federico Cusinato ◽  
Genny Orso ◽  
Paolo Bonaldo ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cell Death ◽  
Small Cell Lung Cancer ◽  
Cancer Cells ◽  
Cell Lung Cancer ◽  
Cardiac Glycoside ◽  
Small Cell ◽  
Autophagic Cell Death ◽  
Lung Cancer Cells ◽  
Small Cell Lung
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