scholarly journals Extraction, Preconcentration and Isolation of Flavonoids from Apocynum venetum L. Leaves Using Ionic Liquid-Based Ultrasonic-Assisted Extraction Coupled with an Aqueous Biphasic System

Molecules ◽  
2016 ◽  
Vol 21 (3) ◽  
pp. 262 ◽  
Author(s):  
Zhijian Tan ◽  
Yongjian Yi ◽  
Hongying Wang ◽  
Wanlai Zhou ◽  
Chaoyun Wang
Molecules ◽  
2019 ◽  
Vol 24 (4) ◽  
pp. 778 ◽  
Author(s):  
Qing Liang ◽  
Jinsong Zhang ◽  
Xingguang Su ◽  
Qingwei Meng ◽  
Jianpeng Dou

Ionic liquids (ILs) are recognized as a possible replacement of traditional organic solvents, and ILs have been widely applied to extract various compounds. The present work aims to extract ginsenosides from Panax ginseng flower buds using aqueous ionic liquid based ultrasonic assisted extraction (IL-UAE). The extraction yields of 1-alkyl-3-methylimidazolium ionic liquids with different anions and alkyl chains were evaluated. The extraction parameters of eight ginsenosides were optimized by utilizing response surface methodology (RSM). The model demonstrated that a high yield of total ginsenosides could be obtained using IL-UAE, and the optimum extraction parameters were 0.23 M [C4mim][BF4], ultrasonic time of 23 min, temperature of extraction set to 30 °C, and liquid-solid ratio of 31:1. After that, an aqueous biphasic system (ABS) was used to separate ginsenosides further. The nature and concentration of salt, as well as the value of pH in ionic liquid were evaluated, and the optimal conditions (6.0 mL IL extract, 3 g NaH2PO4, and pH 5.0) were obtained. The preconcentration factor was 2.58, and extraction efficiency reached 64.53%. The results indicate that as a simple and efficient method, an IL-UAE-ABS can be considered as a promising method for extracting and separating the natural active compounds from medicinal herbs.


2018 ◽  
Vol 20 (24) ◽  
pp. 16477-16484 ◽  
Author(s):  
Vijetha Mogilireddy ◽  
Matthieu Gras ◽  
Nicolas Schaeffer ◽  
Helena Passos ◽  
Lenka Svecova ◽  
...  

This work describes the fundamentals of acid-induced ionic liquid-based ABS system and focuses on understanding the properties of such distinctive system.


2009 ◽  
Vol 640 (1-2) ◽  
pp. 47-51 ◽  
Author(s):  
Xiaoji Cao ◽  
Xuemin Ye ◽  
Yanbin Lu ◽  
Yi Yu ◽  
Weimin Mo

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