scholarly journals A Survey of Marine Natural Compounds and Their Derivatives with Anti-Cancer Activity Reported in 2012

Molecules ◽  
2015 ◽  
Vol 20 (4) ◽  
pp. 7097-7142 ◽  
Author(s):  
Wamtinga Sawadogo ◽  
Rainatou Boly ◽  
Claudia Cerella ◽  
Marie Teiten ◽  
Mario Dicato ◽  
...  
Keyword(s):  
Natural Compounds ◽  
Anti Cancer ◽  
Cancer Activity ◽  
Marine Natural Compounds

scholarly journals A Survey of Marine Natural Compounds and Their Derivatives with Anti-Cancer Activity Reported in 2011

Molecules ◽  
2013 ◽  
Vol 18 (4) ◽  
pp. 3641-3673 ◽  
Author(s):  
Wamtinga Sawadogo ◽  
Marc Schumacher ◽  
Marie-Hélène Teiten ◽  
Claudia Cerella ◽  
Mario Dicato ◽  
...  
Keyword(s):  
Natural Compounds ◽  
Anti Cancer ◽  
Cancer Activity ◽  
Marine Natural Compounds

scholarly journals A Survey of Marine Natural Compounds and Their Derivatives with Anti-Cancer Activity Reported in 2010

Molecules ◽  
2011 ◽  
Vol 16 (7) ◽  
pp. 5629-5646 ◽  
Author(s):  
Marc Schumacher ◽  
Mareike Kelkel ◽  
Mario Dicato ◽  
Marc Diederich
Keyword(s):  
Natural Compounds ◽  
Anti Cancer ◽  
Cancer Activity ◽  
Marine Natural Compounds

scholarly journals Anti-Cancer Activity of Porphyran and Carrageenan from Red Seaweeds

Molecules ◽  
2019 ◽  
Vol 24 (23) ◽  
pp. 4286 ◽  
Author(s):  
Zhiwei Liu ◽  
Tianheng Gao ◽  
Ying Yang ◽  
Fanxin Meng ◽  
Fengping Zhan ◽  
...  
Keyword(s):  
Bioactive Compounds ◽  
Marine Environment ◽  
Animal Health ◽  
Natural Compounds ◽  
Chemotherapeutic Agents ◽  
Chemopreventive Agents ◽  
Red Seaweeds ◽  
Anti Cancer ◽  
Cancer Activity

Seaweeds are some of the largest producers of biomass in the marine environment and are rich in bioactive compounds that are often used for human and animal health. Porphyran and carrageenan are natural compounds derived from red seaweeds. The former is a characteristic polysaccharide of Porphyra, while the latter is well known from Chondrus, Gigartina, and various Eucheuma species, all in Rhodophyceae. The two polysaccharides have been found to have anti-cancer activity by improving immunity and targeting key apoptotic molecules and therefore deemed as potential chemotherapeutic or chemopreventive agents. This review attempts to review the current study of anti-cancer activity and the possible mechanisms of porphyran and carrageenan derived from red seaweeds to various cancers, and their cooperative actions with other anti-cancer chemotherapeutic agents is also discussed.

Evaluation of Selected Natural Compounds for Cancer Stem Cells Targeted Anti-cancer Activity: A Molecular Docking Study

2016 ◽  
Vol 15 (4) ◽  
pp. 1-21 ◽  
Author(s):  
Karthika Mayan ◽  
Sameera Samarakoon ◽  
Kamani Tennekoon ◽  
Asitha Siriwardana ◽  
José Valverde
Keyword(s):  
Stem Cells ◽  
Molecular Docking ◽  
Cancer Stem Cells ◽  
Docking Study ◽  
Natural Compounds ◽  
Molecular Docking Study ◽  
Anti Cancer ◽  
Cancer Activity

ANTICANCER EFFECT OF UVARIA GENUS

2014 ◽  
pp. 98-101
Author(s):  
Thi Bich Hien Le ◽  
Viet Duc Ho ◽  
Thi Hoai Nguyen
Keyword(s):  
Biological Activities ◽  
Current Trend ◽  
Healthcare Systems ◽  
Chemical Compositions ◽  
Cancer Therapies ◽  
Pharmacological Effects ◽  
Anticancer Effect ◽  
Anti Cancer ◽  
Tropical Areas ◽  
Cancer Activity

Nowadays, cancer treatment has been a big challenge to healthcare systems. Most of clinical anti-cancer therapies are toxic and cause adverse effects to human body. Therefore, current trend in science is seeking and screening of natural compounds which possess antineoplastic activities to utilize in treatment. Uvaria L. - Annonaceae includes approximately 175 species spreading over tropical areas of Asia, Australia, Africa and America. Studies on chemical compositions and pharmacological effects of Uvaria showed that several compound classes in this genus such as alkaloid, flavonoid, cyclohexen derivaties, acetogenin, steroid, terpenoid, etc. indicate considerable biological activities, for example anti-tumor, anti-cancer, antibacterial, antifungal, antioxidant, etc. Specifically, anti-cancer activity of fractions of extract and pure isolated compounds stands out for cytotoxicity against many cancer cell lines. This study provides an overview of anti-cancer activity of Uvaria and suggests a potential for further studies on seeking and developing novel anti-cancer compounds. Key words: Anti-cancer, Uvaria.

Role of Resveratrol in Modulating microRNAs in Human Diseases: From Cancer to Inflammatory Disorder

2020 ◽  
Vol 28 (2) ◽  
pp. 360-376 ◽  
Author(s):  
Atefeh Amiri ◽  
Maryam Mahjoubin-Tehran ◽  
Zatollah Asemi ◽  
Alimohammad Shafiee ◽  
Sarah Hajighadimi ◽  
...  
Keyword(s):  
Molecular Mechanisms ◽  
Antioxidant Activities ◽  
Natural Compounds ◽  
Therapeutic Effects ◽  
Inflammatory Disorder ◽  
Inflammatory Disorders ◽  
Therapeutic Modalities ◽  
Anti Cancer ◽  
Current Therapies ◽  
Anti Inflammatory

: Cancer and inflammatory disorders are two important public health issues worldwide with significant socio.economic impacts. Despite several efforts, the current therapeutic platforms are associated with severe limitations. Therefore, developing new therapeutic strategies for the treatment of these diseases is a top priority. Besides current therapies, the utilization of natural compounds has emerged as a new horizon for the treatment of cancer and inflammatory disorders as well. Such natural compounds could be used either alone or in combination with the standard cancer therapeutic modalities such as chemotherapy, radiotherapy, and immunotherapy. Resveratrol is a polyphenolic compound that is found in grapes as well as other foods. It has been found that this medicinal agent displays a wide pharmacological spectrum, including anti-cancer, anti-inflammatory, anti-microbial, and antioxidant activities. Recently, clinical and pre-clinical studies have highlighted the anti-cancer and anti-inflammatory effects of resveratrol. Increasing evidence revealed that resveratrol exerts its therapeutic effects by targeting various cellular and molecular mechanisms. Among cellular and molecular targets that are modulated by resveratrol, microRNAs (miRNAs) have appeared as key targets. MiRNAs are short non-coding RNAs that act as epigenetic regulators. These molecules are involved in many processes that are involved in the initiation and progression of cancer and inflammatory disorders. Herein, we summarized various miRNAs that are directly/indirectly influenced by resveratrol in cancer and inflammatory disorders.

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