scholarly journals Effect of [10]-Gingerol on [Ca2+]i and Cell Death in Human Colorectal Cancer Cells

Molecules ◽  
2009 ◽  
Vol 14 (3) ◽  
pp. 959-969 ◽  
Author(s):  
Chung-Yi Chen ◽  
Yi-Wen Li ◽  
Soong-Yu Kuo
Keyword(s):  
Colorectal Cancer ◽  
Cell Death ◽  
Cancer Cells ◽  
Human Colorectal Cancer ◽  
Colorectal Cancer Cells ◽  
Human Colorectal Cancer Cells

Altholactone Induces Apoptotic Cell Death in Human Colorectal Cancer Cells

2011 ◽  
Vol 26 (6) ◽  
pp. 926-931 ◽  
Author(s):  
Nizar M. Mhaidat ◽  
Kalid K. Abdul-Razzak ◽  
Ahmad S. Alkofahi ◽  
Aseera M. Alsarhan ◽  
Ahmad N. Aldaher ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Cell Death ◽  
Cancer Cells ◽  
Apoptotic Cell ◽  
Apoptotic Cell Death ◽  
Human Colorectal Cancer ◽  
Colorectal Cancer Cells ◽  
Human Colorectal Cancer Cells

Coptidis rhizoma Induces Apoptosis in Human Colorectal Cancer Cells SNU-C4

2004 ◽  
Vol 32 (06) ◽  
pp. 873-882 ◽  
Author(s):  
Youn Jung Kim ◽  
Soon Ah Kang ◽  
Mee Suk Hong ◽  
Hae Jeong Park ◽  
Mi-Ja Kim ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Cell Death ◽  
Cancer Cells ◽  
Caspase 3 ◽  
Apoptotic Cell ◽  
Terminal Deoxynucleotidyl Transferase ◽  
Human Colorectal Cancer ◽  
Colorectal Cancer Cells ◽  
Coptidis Rhizoma ◽  
Human Colorectal Cancer Cells

Coptidis rhizoma has been used as traditional herb medicine in gastrointestinal disorders in the Eastern Asia. We investigated whether the anticancer effects of the C. rhizoma induced apoptosis on human colorectal cancer cells SNU-C4. The cytotoxic effect of C. rhizoma was assessed by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay. To determine apoptotic cell death, 4,6-diamidino-2-phenylindole (DAPI) staining, terminal deoxynucleotidyl transferase (TdT)-mediated dUTP nick end labeling (TUNEL) assay, reverse transcription-polymerase chain reaction (RT-PCR) and caspase-3 enzyme assay were performed. In this study, C. rhizoma treatment (100 μg/ml) revealed typical morphological apoptotic features. Additionally, C. rhizoma treatment (100 μg/ml) increased levels of BAX and CASPASE-3, and decreased levels of BCL-2. Caspase-3 enzyme activity by treatment of C. rhizoma (100 μg/ml) also significantly increased compared to the control (p<0.05). These data indicate that C. rhizoma caused cell death by apoptosis through caspase pathways on human colorectal cancer cells SNU-C4.

scholarly journals Oral poliovirus vaccine-induced programmed cell death involves both intrinsic and extrinsic pathways in human colorectal cancer cells

2018 ◽  
Vol Volume 7 ◽  
pp. 95-105
Author(s):  
Sareh Zhand ◽  
Seyed Masoud Hosseini ◽  
Alijan Tabarraei ◽  
Mohsen Saeidi ◽  
Marie Saghaeian Jazi ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Cell Death ◽  
Programmed Cell Death ◽  
Cancer Cells ◽  
Oral Poliovirus Vaccine ◽  
Human Colorectal Cancer ◽  
Colorectal Cancer Cells ◽  
Human Colorectal Cancer Cells
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