scholarly journals High-Efficiency Catalysis of Peroxymonosulfate by MgO for the Degradation of Organic Pollutants

Minerals ◽  
2019 ◽  
Vol 10 (1) ◽  
pp. 2 ◽  
Author(s):  
Qian Peng ◽  
Xuekun Tang ◽  
Kun Liu ◽  
Xianping Luo ◽  
Dongsheng He ◽  
...  
Keyword(s):  
Singlet Oxygen ◽  
Organic Pollutants ◽  
High Efficiency ◽  
The Novel ◽  
Ph Values ◽  
Interesting Insight ◽  
Wide Range ◽  
First Time ◽  
Insight Into ◽  
Single Factor Experiment

In the study, magnesium oxide (MgO) was used to catalyze peroxymonosulfate (PMS) for the degradation of organic pollutants for the first time. According to the single-factor experiment results, it was determined that MgO could efficiently catalyze PMS to degrade organic matters in a wide range of pH values. Based on radical quenching experiments and electron spinning resonance spectra, singlet oxygen was identified to be the crucial reactive species. Importantly, the oxygen vacancy on the surface of MgO was determined as the key active site, which accelerated the decomposition of PMS to produce singlet oxygen. This study provides an interesting insight into the novel and ignored catalyst of MgO for the highly efficient activation of PMS, which will greatly benefit the Fenton-like catalytic degradation of organic wastewater.

scholarly journals Dynactin integrity depends upon direct binding of dynamitin to Arp1

2014 ◽  
Vol 25 (14) ◽  
pp. 2171-2180 ◽  
Author(s):  
Frances Ka Yan Cheong ◽  
Lijuan Feng ◽  
Ali Sarkeshik ◽  
John R. Yates ◽  
Trina A. Schroer
Keyword(s):  
Affinity Purification ◽  
Cytoplasmic Dynein ◽  
Multiprotein Complex ◽  
Binding Studies ◽  
Intrinsically Disordered ◽  
Cell Functions ◽  
Wide Range ◽  
Direct Binding ◽  
First Time ◽  
Insight Into

Dynactin is a multiprotein complex that works with cytoplasmic dynein and other motors to support a wide range of cell functions. It serves as an adaptor that binds both dynein and cargoes and enhances single-motor processivity. The dynactin subunit dynamitin (also known as p50) is believed to be integral to dynactin structure because free dynamitin displaces the dynein-binding p150Glued subunit from the cargo-binding Arp1 filament. We show here that the intrinsically disordered dynamitin N-terminus binds to Arp1 directly. When expressed in cells, dynamitin amino acids (AA) 1–87 causes complete release of endogenous dynamitin, p150, and p24 from dynactin, leaving behind Arp1 filaments carrying the remaining dynactin subunits (CapZ, p62, Arp11, p27, and p25). Tandem-affinity purification–tagged dynamitin AA 1–87 binds the Arp filament specifically, and binding studies with purified native Arp1 reveal that this fragment binds Arp1 directly. Neither CapZ nor the p27/p25 dimer contributes to interactions between dynamitin and the Arp filament. This work demonstrates for the first time that Arp1 can directly bind any protein besides another Arp and provides important new insight into the underpinnings of dynactin structure.

First Report of the Earthworm Pontoscolex corethrurus (Müller, 1857) from Punjab, India

2018 ◽  
Vol 68 ◽  
pp. 1-8 ◽  
Author(s):  
Sharanpreet Singh ◽  
Jaswinder Singh ◽  
Ayushi Sharma ◽  
Adarsh Pal Vig ◽  
Shakoor Ahmed
Keyword(s):  
Organic Matter ◽  
Life Cycle ◽  
High Efficiency ◽  
Economic Importance ◽  
Edaphic Factors ◽  
Pontoscolex Corethrurus ◽  
Wide Range ◽  
First Time ◽  
Poor Soil ◽  
German Naturalist

The earthwormPontoscolex corethrurus(Müller, 1857) is reported for the first time from Punjab, India. This species was first described by German naturalist Fritz Müller in 1857 from Santa Catarina state of Brazil. It is commonly found in gardens, cropland and fallowlands. It tolerates wide range of climatic and edaphic factors due to its endogeic ecological category.P. corethrurushas high efficiency for organic matter assimilation and has ability to live in new habitat due to which it can survive even in very poor soil. The life cycle of this species is well documented and this species has economic importance due to its use in waste management.

scholarly journals The novel ciliogenesis regulator DYRK2 governs Hedgehog signaling during mouse embryogenesis

eLife ◽  
2020 ◽  
Vol 9 ◽  
Author(s):  
Saishu Yoshida ◽  
Katsuhiko Aoki ◽  
Ken Fujiwara ◽  
Takashi Nakakura ◽  
Akira Kawamura ◽  
...  
Keyword(s):  
Hedgehog Signaling ◽  
Primary Cilia ◽  
Molecular Mechanisms ◽  
The Novel ◽  
Mammalian Development ◽  
Hh Signaling ◽  
Functional Analyses ◽  
First Time ◽  
Insight Into

Mammalian Hedgehog (Hh) signaling plays key roles in embryogenesis and uniquely requires primary cilia. Functional analyses of several ciliogenesis-related genes led to the discovery of the developmental diseases known as ciliopathies. Hence, identification of mammalian factors that regulate ciliogenesis can provide insight into the molecular mechanisms of embryogenesis and ciliopathy. Here, we demonstrate that DYRK2 acts as a novel mammalian ciliogenesis-related protein kinase. Loss of Dyrk2 in mice causes suppression of Hh signaling and results in skeletal abnormalities during in vivo embryogenesis. Deletion of Dyrk2 induces abnormal ciliary morphology and trafficking of Hh pathway components. Mechanistically, transcriptome analyses demonstrate down-regulation of Aurka and other disassembly genes following Dyrk2 deletion. Taken together, the present study demonstrates for the first time that DYRK2 controls ciliogenesis and is necessary for Hh signaling during mammalian development.

scholarly journals Degradation of Oxytetracycline By Magnetic MOFs Heterojunction Photocatalyst With Persulfate : High Stability And Wide Range

2021 ◽  
Author(s):  
Zhuo Zhang ◽  
Chunyan Du ◽  
Yin Zhang ◽  
Guanlong Yu ◽  
Ying Xiong ◽  
...  
Keyword(s):  
Hydrothermal Method ◽  
Removal Efficiency ◽  
Organic Pollutants ◽  
High Stability ◽  
Water Bodies ◽  
Significant Implication ◽  
Ph Values ◽  
Wide Range ◽  
Excellent Stability

Abstract Photocatalysis/Persulfate is an effective method of degrading organic pollutants. In this study, Fe3O4/MIL-101(Fe), a magnetic heterojunction photocatalyst, was produced by hydrothermal method. The material exhibited excellent removal efficiency for OTC in the coupling of persulfate (87.1%, 1 h). And it has a wide range of applications, with good removal efficiency for OTC concentrations of 30 to 70 mg/L and pH values of 3 to 9. •SO4− and •OH played a major role in the OTC removal reaction and there was an Fe(III)/Fe(II) cycle during the reaction. With excellent stability and recoverability, the OTC removal efficiency decreased by only 4.29% after four cycles, and the Fe leaching did not exceed 0.035 mg/L per cycle. This has a significant implication for the removal of organic pollutants from water bodies.

Alfred Schnittke's Concerto Grosso no. 1

2019 ◽  
Author(s):  
Peter J. Schmelz
Keyword(s):  
Soviet Union ◽  
Primary Sources ◽  
The Novel ◽  
Concerto Grosso ◽  
The Soviet Union ◽  
Novel Structure ◽  
New Information ◽  
Wide Range ◽  
Serial Music ◽  
First Time

This book provides for the first time an accessible, comprehensive study of Alfred Schnittke’s Concerto Grosso no. 1 (1977). One of Schnittke’s best-known and most compelling works, the Concerto Grosso no. 1 sounds the surface of late Soviet life, resonating as well with contemporary compositional currents around the world. This innovative monograph builds on existing publications about the Concerto Grosso no. 1 in English, Russian, and German, augmenting and complicating them. It adds new information from underused primary sources, including Schnittke’s unpublished correspondence and his many published interviews. It also engages further with his sketches for the Concerto Grosso no. 1 and contemporary Soviet musical criticism. The result is a more objective, historical appraisal of this rich, multifaceted composition. The Concerto Grosso no. 1 provided a utopian model of the contemporary soundscape. It was a decisive point in Schnittke’s development of the approach he called polystylism, which aimed to contain in a single composition the wide range of contemporary musical styles, including jazz, pop, rock, and serial music. Thanks to it and his other similar compositions, Schnittke became one of the most-performed and most-recorded living composers at the end of the twentieth century. The novel structure of this book engages the Concerto Grosso no. 1 conceptually, historically, musically, and phenomenologically: the six movements of the composition frame the six chapters. The present volume thus provides a holistic accounting of Schnittke’s Concerto Grosso no. 1, its influences, and its impact on subsequent music making in the Soviet Union and worldwide.

scholarly journals An efficient recyclable magnetic material for the selective removal of organic pollutants

2016 ◽  
Vol 7 ◽  
pp. 1447-1453 ◽  
Author(s):  
Clément Monteil ◽  
Nathalie Bar ◽  
Agnès Bee ◽  
Didier Villemin
Keyword(s):  
Organic Pollutants ◽  
Polymer Coating ◽  
Magnetic Core ◽  
Maghemite Nanoparticles ◽  
Step Process ◽  
Ph Values ◽  
Low Concentrations ◽  
Wide Range ◽  
One Step ◽  
Harsh Conditions

Wastewater cleaning strategies based on the adsorption of materials are being increasingly considered, but the wide variety of organic pollutants at low concentrations still makes their removal a challenge. The hybrid material proposed here consists of a zwitterionic polyethylenimine polymer coating a magnetic core. Polyethylenimine is phosphonated at different percentages by a one-step process and used to coat maghemite nanoparticles. It selectively extracts high amounts of cationic and anionic contaminants over a wide range of pH values, depending on the adjustable number of phosphonate groups introduced on the polymer. After recovering the nanoparticles with a magnet, pollutants are quantitatively released by repeated washing with low amounts of pH-adjusted water. The material can be reused many times without noticeable loss of efficiency and is designed to resist high temperatures, oxidation and harsh conditions.

scholarly journals The temporal correlation between positive testing and death in Italy: from the first phase to the later evolution of the COVID-19 pandemic

2021 ◽  
Author(s):  
Vincenzo d'Alessandro ◽  
Nicole Balasco ◽  
Pietro Ferrara ◽  
Luigi Vitagliano
Keyword(s):  
Phase 1 ◽  
Temporal Correlation ◽  
Mean Value ◽  
The Novel ◽  
Temporal Shift ◽  
Interesting Insight ◽  
Global Spread ◽  
Novel Coronavirus ◽  
The Impact ◽  
Insight Into

After the global spread of the novel coronavirus disease 2019 (COVID-19), research has concentrated its efforts on several aspects of the epidemiological burden of pandemic. In this frame, the presented study follows a previous analysis of the temporal link between cases and deaths during the first epidemic wave (Phase 1) in Italy (March-June 2020). We here analyze the COVID-19 epidemic in the time span from March 2020 to June 2021. The elaboration of the curves of cases and deaths allows identifying the temporal shift between the positive testing and the fatal event, which corresponds to one week from W2 to W33, two weeks from W34 to W41, and three weeks from W42 to W67. Based on this finding, we calculate the Weekly Lethality Rate (WLR). The WLR was grossly overestimated (~13.5%) in Phase 1, while a mean value of 2.6% was observed in most of Phase 2 (starting from October 2020), with a drop to 1.4% in the last investigated weeks. Overall, these findings offer an interesting insight into the magnitude and time evolution of the lethality burden attributable to COVID-19 during the entire pandemic period in Italy. In particular, the analysis highlighted the impact of the effectiveness of public health and social measures, of changes in disease management, and of preventive strategies over time.

scholarly journals “Making meaning”: Communication between sign language users without a shared language

2015 ◽  
Vol 26 (2) ◽  
pp. 211-260 ◽  
Author(s):  
Ulrike Zeshan
Keyword(s):  
Small Group ◽  
Sign Language ◽  
Conceptual Blending ◽  
Making Meaning ◽  
Multimodal Interactions ◽  
Wide Range ◽  
Shared Language ◽  
First Time ◽  
Insight Into

AbstractIn a small group of deaf sign language users from different countries and with no shared language, the signers’ initial conversational interactions are investigated as they meet in pairs for the very first time. This case study allows for a unique insight into the initial stages of pidginisation and the conceptual processes involved. The participants use a wide range of linguistic and communicative resources, and it can be argued that they construct shared multilingual-multimodal cognitive spaces for the purpose of these conversations. This research explores the nature of these shared multilingual-multimodal spaces, how they are shaped by the signers in interaction, and how they can be understood in terms of conceptual blending. The research also focuses on the meta-linguistic skills that signers use in these multilingual-multimodal interactions to “make meaning”.

Synthesis of 3,5-ditetrazolyl-1,2,4-triazole-based complexes: a strategy for developing C–N-linked triheterocyclic energetic compounds

2019 ◽  
Vol 43 (12) ◽  
pp. 4975-4979 ◽  
Author(s):  
Le Wu ◽  
Piao He ◽  
Zhimin Li ◽  
Qianyou Wang ◽  
Junqing Yang ◽  
...  
Keyword(s):  
Energetic Materials ◽  
The Novel ◽  
Energetic Compounds ◽  
Design And Synthesis ◽  
First Time ◽  
Insight Into

Two complexes based on the novel C–N-linked triheterocyclic compound 3,5-ditetrazolyl-1,2,4-triazole (DTT) were reported for the first time. The present study has contributed to the field of C–N-linked polyheterocyclic systems and has provided a new insight into the design and synthesis of new energetic materials.

scholarly journals Label-Free Optical Detection of Mycotoxins Using Specific Aptamers Immobilized on Gold Nanostructures

Toxins ◽  
2018 ◽  
Vol 10 (7) ◽  
pp. 291 ◽  
Author(s):  
Ali Ghanim Al-Rubaye ◽  
Alexei Nabok ◽  
Gaelle Catanante ◽  
Jean-Louis Marty ◽  
Eszter Takács ◽  
...  
Keyword(s):  
Aflatoxin B1 ◽  
Localized Surface Plasmon ◽  
The Novel ◽  
Label Free ◽  
Binding Characteristics ◽  
Highly Sensitive ◽  
Wide Range ◽  
Dna Chain ◽  
First Time ◽  
Kinetics Of

This work focuses on the development of the novel label-free optical apta-sensors for detection of mycotoxins. A highly sensitive analytical method of total internal reflection ellipsometry (TIRE) combined with Localized Surface Plasmon Resonance (LSPR) phenomenon in nano-structured gold films was exploited here for the first time for detection of aflatoxin B1 and M1 in direct assay with specific aptamers immobilized on the surface of gold. The achieved detection of low molecular weight molecules, such as aflatoxin B1 and M1, in a wide range of concentrations from 100 ng/mL down to 0.01 ng/mL is remarkable for the LSPR method. The study of binding kinetics of aflatoxin molecules to their respective aptamers using dynamic TIRE measurements yielded the values of affinity constants in the range of 10−8–10−7 mol, which is characteristic for highly specific aptamer/target interactions similar to that for monoclonal antibodies. The effect of aptamers’ DNA chain length on their binding characteristics was analyzed.

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