scholarly journals The Bond Strength and Antibacterial Activity of the Universal Dentin Bonding System: A Systematic Review and Meta-Analysis

2021 ◽  
Vol 9 (6) ◽  
pp. 1230
Author(s):  
Louis Hardan ◽  
Rim Bourgi ◽  
Carlos Enrique Cuevas-Suárez ◽  
Maciej Zarow ◽  
Naji Kharouf ◽  
...  

Streptococcus mutans (S. mutans) is a group of viridans mostly located in oral flora among the wide and biodiverse biofilm. It plays a significant role not only in caries formation but also triggering intracerebral haemorrhage. The durable and stable bond interface, besides bacteria elimination, is one of the crucial factors influencing the resin composite restoration performance. This study aimed to evaluate universal adhesives (UAs) with regard to in vitro bond strength to dentin, and the inhibition of the S. mutans growth and compare them with UAs modified with antimicrobial agents through a systematic review and meta-analysis. Two reviewers performed a literature search up to April 2021 in 5 electronic databases: PubMed MedLine, Scielo, ISI Web of Science, Scopus, and EMBASE. Only in vitro studies reporting the effect of modifying UAs with antimicrobial agents on the bond strength to dentin and/or on the inhibition of the S. mutans were included. Analyses were carried out using Review Manager Software version 5.3.5 (The Nordic Cochrane Centre, The Cochrane Collaboration, Copenhagen, Denmark). The methodological quality of each in vitro study was evaluated following the parameters of a previous systematic review. A total of 1716 potentially relevant publications were recognized. After reviewing the title and abstract, 16 studies remained in the systematic review. From these, a total of 3 studies were included in the meta-analysis. Since data from the studies included in the antimicrobial outcome included zero values, they could not be meta-analysed. Including 0 values in the analysis will lead to several biases in the analysis, so these data were discarded. The antibacterial effect against S. mutans of UAs modified with antimicrobial agents was higher than the non-modified adhesive systems. Within the limitations of the present study, the bond strength of UAs to dentin could be improved by using antimicrobial agents. The UAs modified with antibacterial agents showed a decrease in the viability of S. mutans biofilm, among the adhesives tested. However, there are not enough valid data on antibacterial properties of modified UAs; therefore, more well-designed research on these materials is needed.

Polymers ◽  
2021 ◽  
Vol 13 (5) ◽  
pp. 814
Author(s):  
Louis Hardan ◽  
Rim Bourgi ◽  
Naji Kharouf ◽  
Davide Mancino ◽  
Maciej Zarow ◽  
...  

Currently, the availability of a wide variety of universal adhesives makes it difficult for clinicians to choose the correct system for specific bonding situations to dentin substrate. This study aimed to determine whether there are any alternative techniques or additional strategies available to enhance the bond strength of universal adhesives to dentin through a systematic review and meta-analysis. Two reviewers executed a literature search up to September 2020 in four electronic databases: PubMed, ISI Web of Science, Scopus, and EMBASE. Only in vitro studies that reported the dentin bond strength of universal adhesives using additional strategies were included. An analysis was carried out using Review Manager Software version 5.3.5 (The Nordic Cochrane Centre, The Cochrane Collaboration, Copenhagen, Denmark). The methodological quality of each in vitro study was assessed according to the parameters of a previous systematic. A total of 5671 potentially relevant studies were identified. After title and abstract examination, 74 studies remained in systematic review. From these, a total of 61 studies were included in the meta-analysis. The bond strength of universal adhesives to dentin was improved by the use of one of the following techniques: Previous application of matrix metalloproteinases (MMP) inhibitors (p < 0.001), prolonged application time (p = 0.007), scrubbing technique (p < 0.001), selective dentin etching (p < 0.001), non-atmospheric plasma (p = 0.01), ethanol-wet bonding (p < 0.01), prolonged blowing time (p = 0.02), multiple layer application (p = 0.005), prolonged curing time (p = 0.006), and hydrophobic layer coating (p < 0.001). On the other hand, the use of a shortened application time (p = 0.006), and dentin desensitizers (p = 0.01) impaired the bond strength of universal adhesives to dentin. Most of the analyses performed showed a high heterogenicity. The in vitro evidence suggests that the application of universal adhesives using some alternative techniques or additional strategies may be beneficial for improving their bonding performance to dentin. This research received no external funding. Considering that this systematic review was carried out only with in vitro studies, registration was not performed.


2021 ◽  
Vol 11 (14) ◽  
pp. 6349
Author(s):  
Regina María Del Río Carrillo ◽  
Pedro Molinero-Mourelle ◽  
Vicente Vera ◽  
Pablo Romero Villaba ◽  
Elizabeth Casañas ◽  
...  

To evaluate the bond strength of different universal adhesives on deciduous tooth dentineand their relationship with the composition and potential of hydrogen (pH). Methods: An in vitromicro push-out test on 150 samples (n = 50) per group per adhesive, namely, Adhese Universal(ADH; Ivoclar Vivadent), Futurabond U (FUT; Voco GmbH) (Test), and Scotchbond Universal withpre-conditioning (SCO; 3M) (Control), to record bond strength (BS) and type of adhesive failure.Results: The results of the different adhesives (megapascals (MPa)) varied, showing no statisticalsignificance. The corresponding averages are in MPa: ADH, 13.66 2.81; FUT, 14.48 2.88; SCO,14.98 3.96. Additionally, the frequency of type of failure was as follows: mixed (60.7%), adhesive(27.3%), and cohesive (12%). Conclusions: SCO, with a pH of 2.7, showed greater resistance tofracture, while FUT, with a pH of 2.3 and no pre-conditioning, approached the same values, being aone-step adhesive. No relationship was found between failure and type of adhesive.


Materials ◽  
2020 ◽  
Vol 13 (19) ◽  
pp. 4383
Author(s):  
Barbara Lapinska ◽  
Aleksandra Szram ◽  
Beata Zarzycka ◽  
Janina Grzegorczyk ◽  
Louis Hardan ◽  
...  

Modifying the composition of dental restorative materials with antimicrobial agents might induce their antibacterial potential against cariogenic bacteria, e.g., S.mutans and L.acidophilus, as well as antifungal effect on C.albicans that are major oral pathogens. Essential oils (EOs) are widely known for antimicrobial activity and are successfully used in dental industry. The study aimed at evaluating antibacterial and antifungal activity of EOs and composite resin material (CR) modified with EO against oral pathogens. Ten EOs (i.e., anise, cinnamon, citronella, clove, geranium, lavender, limette, mint, rosemary thyme) were tested using agar diffusion method. Cinnamon and thyme EOs showed significantly highest antibacterial activity against S.mutans and L.acidophilus among all tested EOs. Anise and limette EOs showed no antibacterial activity against S.mutans. All tested EOs exhibited antifungal activity against C.albicans, whereas cinnamon EO showed significantly highest and limette EO significantly lowest activity. Next, 1, 2 or 5 µL of cinnamon EO was introduced into 2 g of CR and microbiologically tested. The modified CR showed higher antimicrobial activity in comparison to unmodified one. CR containing 2 µL of EO showed the best antimicrobial properties against S.mutans and C.albicans, while CR modified with 1 µL of EO showed the best antimicrobial properties against L.acidophilus.


Materials ◽  
2021 ◽  
Vol 14 (21) ◽  
pp. 6694
Author(s):  
Flavia Iaculli ◽  
Alessandro Salucci ◽  
Gianni Di Giorgio ◽  
Valeria Luzzi ◽  
Gaetano Ierardo ◽  
...  

Background: Conventional composites are largely used in pediatric restorative dentistry and demonstrate successful clinical outcomes. However, the need for simplification of operative steps in young or uncooperative children demands reliable alternatives. Therefore, the aim of the present systematic review and meta-analysis was to evaluate the in vitro bond strength of glass ionomer cements (GICs) and self-adhesive flowable composites (SFCs) on deciduous teeth. Methods: A comprehensive literature search according to the PRISMA checklist was manually and electronically performed by two independent reviewers through the following databases: MEDLINE/PubMed, Google Scholar, Scopus, and Embase, to include in vitro studies comparing GICs and SFCs bond strength values of restorations on primary teeth. In addition, three groups of meta-analyses were conducted using random-effects models. Results: Three articles meeting the inclusion criteria were selected and subjected to both qualitative and quantitative assessment. No statistically significant difference was found between SFC versus GIC; however, both groups significantly differed with conventional flowable composites (CFs). Conclusions: Despite the absence of significant difference in bond strength values, SFCs may be considered a valid alternative to GICs in the restoration of deciduous teeth, although CFs proved better in vitro performances.


2020 ◽  
Vol 8 (10) ◽  
pp. 454-459
Author(s):  
Bhalla V. ◽  
◽  
K. Goud M. ◽  
Chockattu S. ◽  
Khera A ◽  
...  

Background:Dentin bonding is an ever-evolving field in adhesive dentistry. With the introduction of newer systems into the market, there is a crucial need to test their efficiency in terms of bond strength. Dual-cured adhesives in theory may provide for a better degree of conversion as compared to conventional light-cured adhesives .Thus, the aim of this study was to compare the shear bond strength of three different self-etch adhesives namely ClearfilSE bond (Kuraray), Tetric N Bond Universal (IvoclarVivadent) and Futura Bond DC (Voco) to dentin. Materials & Methods: Ninety extracted non-carious, intact human mandibular molar teeth were selected for this study. Each tooth was decoronated using a double-sided diamond disc with water coolant to a depth of 2mm from the cusp tip .The cut dentin surface was then abraded against 600-grit wet silicon carbide papers for 60 seconds to produce a uniform smear layer. The root portion of each tooth was mounted on a plastic ring using cold cure acrylic resin. Specimens were then divided into three adhesive groups of 30 teeth each, Group A: ClearfilSE Bond (Kuraray), Group B: Tetric N Bond Universal (IvoclarVivadent), Group C :Futura Bond DC (Voco). All bonding agents were used according to the manufacturers’ instructions, in combination with the resin composite Tetric N Ceram (IvoclarVivadent). The samples were thermocycled, followed by shear bond strength testing using a Universal testing machine (Hounsfield). Data were subjected to statistical analysis using one-way analysis of variance (ANOVA) (P<0.05) and Post hoc Tukey’s test for inter- and intra- group analysis respectively. Results: Clearfil SE Bond yielded the highest shear bond strength values (30.9 ±4.66 MPa) which were statistically significant, followed byTetric N Bond Universal group (29.8 ±4.34) and the lowest shear bond strength values were recorded for Futura Bond DC (18.2 ±3.13). Conclusion: Clearfil SE bond and Tetric N bond Universal can be considered as better options than Futura Bond DC.


2019 ◽  
Vol 11 (7) ◽  
pp. 515 ◽  
Author(s):  
KrantiKiran Reddy Ealla ◽  
AshokBabu Devatha ◽  
MNarasimha Lakshmi ◽  
NareshB Kumar ◽  
Srikanth Erukala ◽  
...  

2021 ◽  
Vol 2021 ◽  
pp. 1-9
Author(s):  
Taksid Charasseangpaisarn ◽  
Pattarawadee Krassanairawiwong ◽  
Chanidapa Sangkanchanavanich ◽  
Atima Kurjirattikan ◽  
Kanyarak Kunyawatyuwapong ◽  
...  

Background and Purpose. Contamination of the lithium disilicate (LDS) during the try-in procedure is unavoidable and may weaken the bond strength of restoration. The purpose of this study was to investigate the efficacy of different surface cleansing agents on the shear bond strength (SBS) of contaminated LDS. Materials and Methods. Seventy LDS specimens were randomly divided into seven groups. The first group was noncontaminated surface (PC). The six other groups were contaminated with the saliva and silicone disclosing medium and treated with no surface cleansing agent (NC); phosphoric acid (PO); Ivoclean (IV); sodium hydroxide solution (NA); Restorative Cleansing Agent (RC); and hydrofluoric acid (HF). Then, LDS specimens were cementated with Panavia V5 to resin composite rod. Each specimen was subjected to an SBS test. The modes of failure was inspected under light microscope. The surface element of each group was examined by SEM-EDS. Results. The results were analyzed with one-way ANOVA and Tamhane’s T2. The mean SBS value of NC was significantly lower than others ( p < 0.05 ), and HF was significantly higher than others ( p < 0.05 ). However, PC, PO, IV, NA, and RC were not significantly different from each other ( p > 0.05 ). The mode of failure was mostly adhesive failure in every group. The surface showed similar amount of elements in every group. Conclusions. The SBS of LDS was reduced by saliva and silicone disclosing medium contamination which can be restored using acid- and alkaline-based surface cleansing agents before the cementation procedure.


Author(s):  
Masoud Fallahinejad Ghajari ◽  
Mahsa Sheikholeslamian ◽  
Amir Ghasemi ◽  
Leila Simaei

Objectives: This study aimed to determine the microtensile bond strength (μTBS) of a bulk-fill composite to permanent and primary coronal dentin using a universal adhesive in self-etch and total-etch modes. Materials and Methods: This in-vitro study was performed on 52 occlusal dentinal surfaces of human primary and permanent teeth. The crowns were cut to the gingival level. The 48 prepared dentin sections were randomly assigned to the following groups (n=13): A: Primary/Total-etch, B: Primary/Self-etch, C: Permanent/Total-etch, and D: Permanent/Self-etch. In groups A and C, after etching for 15 seconds, two layers of a universal bonding (Futurabond U) were applied and cured for 10 seconds. All samples were filled with a bulk-fill composite (x-trafil; VOCO) and cured for 40 seconds. The samples were cut to a bar-shaped dentin block with the dimensions of 1×1×1 mm3, and after 10,000 thermocycles, the μTBS test was accomplished at a crosshead speed of 1 mm/minute. The mean and standard deviation (SD) of μTBS were calculated, and the data were analyzed using two-way analysis of variance (ANOVA) and Fisher's exact test. Results: The mean μTBS was as follows: A: 15.03±2.0279, B: 11.11±2.4423, C: 23.50±4.8165, and D: 16.26±6.3200 MPa. Futurabond U showed a higher μTBS in the total-etch mode (P<0.001). The permanent teeth had greater μTBS than the primary teeth (P<0.001). Similar percentages of failure modes were observed in the total-etch groups but in the self-etch groups, most failures were in the form of adhesive and mixed. Conclusion: Greater μTBS was observed in the permanent teeth with the total-etch technique.


2019 ◽  
Vol 22 (5) ◽  
pp. 483
Author(s):  
Suresh Mitthra ◽  
Lukram Nivedita ◽  
Venkatachalam Prakash ◽  
NewbeginSelvakumar Gold Pearlin Mary ◽  
Alagarsamy Venkatesh ◽  
...  

2022 ◽  
Vol 9 (1) ◽  
pp. 14
Author(s):  
Inês Francisco ◽  
Raquel Travassos ◽  
Catarina Nunes ◽  
Madalena Ribeiro ◽  
Filipa Marques ◽  
...  

Background: There has been an increase in demand for orthodontic treatment within the adult population, who likely receive restorative treatments using ceramic structures. The current state of the art regarding the most effective method to achieve an appropriate bond strength of brackets on ceramic surfaces isn’t consensual. This systematic review aims to compare the available surface treatments to ceramics and determine the one that allows to obtain the best bond strength. Methods: This systematic review followed the PRISMA guidelines and the PICO methodology was used, with the question “What is the most effective technique for bonding brackets on ceramic crowns or veneers?”. The research was carried out in PubMed, Web of Science, Embase and Cochrane Library databases. In vitro and ex vivo studies were included. The methodological quality was evaluated using the guidelines for reporting of preclinical studies on dental materials by Faggion Jr. Results: A total of 655 articles searched in various databases were initially scrutinized. Sevety one articles were chosen for quality analysis. The risk of bias was considered medium to high in most studies. The use of hydrofluoric acid (HF), silane and laser afforded the overall best results. HF and HF plus laser achieved significantly highest bond strength scores in felsdphatic porcelain, while laser was the best treatment in lithium disilicate ceramics. Conclusions: The most effective technique for bonding brackets on ceramic is dependent on the type of ceramic.


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