scholarly journals Epidemiology of Mucormycosis in India

2021 ◽  
Vol 9 (3) ◽  
pp. 523
Author(s):  
Hariprasath Prakash ◽  
Arunaloke Chakrabarti
Keyword(s):  
Risk Factor ◽  
Organ Transplant ◽  
Disease Process ◽  
Population Based ◽  
Medical Attention ◽  
Solid Organ ◽  
Rhizopus Microsporus ◽  
Transplant Patients ◽  
Causative Agents ◽  
Rhizopus Homothallicus

Mucormycosis is an angioinvasive disease caused by saprophytic fungi of the order Mucorales. The exact incidence of mucormycosis in India is unknown due to the lack of population-based studies. The estimated prevalence of mucormycosis is around 70 times higher in India than that in global data. Diabetes mellitus is the most common risk factor, followed by haematological malignancy and solid-organ transplant. Patients with postpulmonary tuberculosis and chronic kidney disease are at additional risk of developing mucormycosis in this country. Trauma is a risk factor for cutaneous mucormycosis. Isolated renal mucormycosis in an immunocompetent host is a unique entity in India. Though Rhizopus arrhizus is the most common etiological agent of mucormycosis in this country, infections due to Rhizopus microsporus, Rhizopus homothallicus, and Apophysomyces variabilis are rising. Occasionally, Saksenaea erythrospora, Mucor irregularis, and Thamnostylum lucknowense are isolated. Though awareness of the disease has increased among treating physicians, disease-associated morbidity and mortality are still high, as patients seek medical attention late in the disease process and given the low affordability for therapy. In conclusion, the rise in the number of cases, the emergence of new risk factors and causative agents, and the challenges in managing the disease are important concerns with mucormycosis in India.

Evaluation of Pulmonary Infections in Solid Organ Transplant Patients: 12 Years of Experience

2013 ◽  
Vol 45 (10) ◽  
pp. 3458-3461 ◽  
Author(s):  
F.Ö. Eyüboğlu ◽  
E. Küpeli ◽  
Ş.S. Bozbaş ◽  
Z.E. Özen ◽  
E.S. Akkurt ◽  
...  
Keyword(s):  
Organ Transplant ◽  
Solid Organ Transplant ◽  
Solid Organ ◽  
Years Of Experience ◽  
Pulmonary Infections ◽  
Transplant Patients

Characteristics and Survival Patterns of Solid Organ Transplant Patients Developing De Novo Colon and Rectal Cancer

2004 ◽  
Vol 47 (11) ◽  
pp. 1898-1903 ◽  
Author(s):  
Harry T. Papaconstantinou ◽  
Bradford Sklow ◽  
Michael J. Hanaway ◽  
Thomas G. Gross ◽  
Thomas M. Beebe ◽  
...  
Keyword(s):  
Rectal Cancer ◽  
De Novo ◽  
Organ Transplant ◽  
Solid Organ Transplant ◽  
Solid Organ ◽  
Transplant Patients ◽  
Colon And Rectal Cancer ◽  
Survival Patterns

Donor-derived infections in solid organ transplant patients

2017 ◽  
Vol 30 (4) ◽  
pp. 329-339 ◽  
Author(s):  
Esther Benamu ◽  
Cameron R. Wolfe ◽  
José G. Montoya
Keyword(s):  
Organ Transplant ◽  
Solid Organ Transplant ◽  
Solid Organ ◽  
Transplant Patients

CT Findings in Solid Organ Transplant Patients With Sirolimus-Associated Lung Toxicity

CHEST Journal ◽  
2017 ◽  
Vol 152 (4) ◽  
pp. A608
Author(s):  
Faisal Khateeb ◽  
Zaid Ammari ◽  
Aahd Kubbara ◽  
Yousef Abdel-Aziz ◽  
Fadi Safi
Keyword(s):  
Organ Transplant ◽  
Solid Organ Transplant ◽  
Lung Toxicity ◽  
Solid Organ ◽  
Transplant Patients ◽  
Ct Findings

scholarly journals 1738. Incidence and Outcomes of Hospitalization with Invasive Fungal Infection Among Solid-Organ Transplant Recipients: A Population-Based Cohort Study

2019 ◽  
Vol 6 (Supplement_2) ◽  
pp. S636-S636
Author(s):  
Kyla L Naylor ◽  
Alexandra Ouédraogo ◽  
Sarah E Bota ◽  
Shahid Husain ◽  
J Michael Paterson ◽  
...  
Keyword(s):  
Cohort Study ◽  
Graft Failure ◽  
Organ Transplant ◽  
Population Based ◽  
Solid Organ Transplant ◽  
Cumulative Probability ◽  
Solid Organ ◽  
Transplant Recipients ◽  
All Cause Mortality

Abstract Background Invasive fungal infection (IFI) in solid-organ transplant (SOT) recipients is associated with significant morbidity and mortality. The long-term probability of post-transplant IFI is poorly understood. Methods We conducted a population-based cohort study using linked administrative healthcare databases from Ontario, Canada to determine the incidence rate, 1-, 5- and 10-year cumulative probability of IFI-related hospitalization, and 1-year post-IFI all-cause mortality in SOT recipients from 2002 to 2016. We also examined post-IFI death-censored graft failure in renal transplant patients. Results We included 9326 SOT recipients (median follow-up 5.35 years). Overall, the incidence of IFI was 8.3 per 1000 person-years (95% confidence interval [CI]: 7.5–9.1). The 1-year cumulative probability of IFI was 7.4% (95% CI: 5.8–9.3%), 5.4% (95% CI: 3.6–8.1%), 1.8% (95% CI: 1.3–2.5%), 1.2% (95% CI: 0.5–3.2%), and 1.1% (95% CI: 0.9–1.4%) for lung, heart, liver, kidney-pancreas, and kidney-only transplant recipients, respectively. Lung transplant recipients had both the highest incidence rate and the highest 10-year probability of IFI: 43.0 per 1,000 person-years (95% CI: 36.8–50.0) and 26.4% (95% CI: 22.4–30.9%), respectively. Lung transplantation was also associated with the highest 1-year cumulative probability of post-IFI all-cause mortality (40.2%,95% CI: 33.1–48.3%). Among kidney transplant recipients, the 1-year probability of death-censored graft failure after IFI was 9.8% (95% CI: 6.0–15.8%). Conclusion The 1-year cumulative probability of IFI varies widely among SOT recipients. Lung transplantation was associated with the highest incidence of IFI with considerable 1-year all-cause mortality. The findings of this study considerably improved our understanding of the long-term probability of post-transplant IFI. Disclosures All authors: No reported disclosures.

Pulmonary Aspergillosis in Solid Organ Transplant Patients: A Report From Iran

2008 ◽  
Vol 40 (10) ◽  
pp. 3663-3667 ◽  
Author(s):  
M. Marjani ◽  
P. Tabarsi ◽  
K. Najafizadeh ◽  
F.R. Farokhi ◽  
B. Sharifkashani ◽  
...  
Keyword(s):  
Organ Transplant ◽  
Solid Organ Transplant ◽  
Solid Organ ◽  
Pulmonary Aspergillosis ◽  
Transplant Patients
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