scholarly journals Impact of Intestinal Microbiota on Growth and Feed Efficiency in Pigs: A Review

2020 ◽  
Vol 8 (12) ◽  
pp. 1886
Author(s):  
Gillian E. Gardiner ◽  
Barbara U. Metzler-Zebeli ◽  
Peadar G. Lawlor
Keyword(s):  
Lipid Metabolism ◽  
Environmental Factors ◽  
Inflammatory Response ◽  
Large Intestine ◽  
Intestinal Microbiota ◽  
Feed Efficiency ◽  
Metabolic Pathways ◽  
Energy Harvest ◽  
Breeding Strategies ◽  
Nutrient Processing

This review summarises the evidence for a link between the porcine intestinal microbiota and growth and feed efficiency (FE), and suggests microbiota-targeted strategies to improve productivity. However, there are challenges in identifying reliable microbial predictors of host phenotype; environmental factors impact the microbe–host interplay, sequential differences along the intestine result in segment-specific FE- and growth-associated taxa/functionality, and it is often difficult to distinguish cause and effect. However, bacterial taxa involved in nutrient processing and energy harvest, and those with anti-inflammatory effects, are consistently linked with improved productivity. In particular, evidence is emerging for an association of Treponema and methanogens such as Methanobrevibacter in the small and large intestines and Lactobacillus in the large intestine with a leaner phenotype and/or improved FE. Bacterial carbohydrate and/or lipid metabolism pathways are also generally enriched in the large intestine of leaner pigs and/or those with better growth/FE. Possible microbial signalling routes linked to superior growth and FE include increased intestinal propionate production and reduced inflammatory response. In summary, the bacterial taxa and/or metabolic pathways identified here could be used as biomarkers for FE/growth in pigs, the taxa exploited as probiotics or the taxa/functionality manipulated via dietary/breeding strategies in order to improve productivity in pigs.

Chemical Ecology and Off-Flavour Substances

1988 ◽  
Vol 20 (8-9) ◽  
pp. 167-178
Author(s):  
O. M. Skulberg
Keyword(s):  
Environmental Factors ◽  
Chemical Ecology ◽  
Aquatic Environment ◽  
Metabolic Pathways ◽  
Chemical Properties ◽  
Relevant Research ◽  
Fundamental Research ◽  
Biotic Effects ◽  
Ecological Mechanisms ◽  
Ecological Importance

Off-flavour substances may be regarded as a resource which can be used to study special ecological mechanisms. Relevant research on off-flavours is inextricably combined with the study of perception, ethology, genetic control etc. The chemicals concerned are commonly perceived by the senses of olfaction and gustation. Thus research on the chemical ecology of off-flavour substances in the aquatic environment involves the study of a variety of disciplines. For example the biochemistry of the relevant substances and appropriate metabolic pathways must be considered. Chemical properties are important for the behaviour of the substances. The production of off-flavours by organisms is related to phenological circumstances. The biotic effects of ecologically significant substances are dependent on several environmental factors. This paper draws attention to the possible application of fundamental research in this area to selected problems of ecological importance.

scholarly journals Placental 13C-DHA metabolism and relationship with maternal BMI, glycemia and birthweight

2021 ◽  
Vol 27 (1) ◽  
Author(s):  
Oliver C. Watkins ◽  
Preben Selvam ◽  
Reshma Appukuttan Pillai ◽  
Victoria K. B. Cracknell-Hazra ◽  
Hannah E. J. Yong ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Liquid Chromatography ◽  
Lipid Metabolism ◽  
Metabolic Pathways ◽  
Liquid Chromatography Mass Spectrometry ◽  
Fasting Glycemia ◽  
Glucose Treatment ◽  
Maternal Bmi

Abstract Background Fetal docosahexaenoic acid (DHA) supply relies on preferential transplacental transfer, which is regulated by placental DHA lipid metabolism. Maternal hyperglycemia and obesity associate with higher birthweight and fetal DHA insufficiency but the role of placental DHA metabolism is unclear. Methods Explants from 17 term placenta were incubated with 13C-labeled DHA for 48 h, at 5 or 10 mmol/L glucose treatment, and the production of 17 individual newly synthesized 13C-DHA labeled lipids quantified by liquid chromatography mass spectrometry. Results Maternal BMI positively associated with 13C-DHA-labeled diacylglycerols, triacylglycerols, lysophospholipids, phosphatidylcholine and phosphatidylethanolamine plasmalogens, while maternal fasting glycemia positively associated with five 13C-DHA triacylglycerols. In turn, 13C-DHA-labeled phospholipids and triacylglycerols positively associated with birthweight centile. In-vitro glucose treatment increased most 13C-DHA-lipids, but decreased 13C-DHA phosphatidylethanolamine plasmalogens. However, with increasing maternal BMI, the magnitude of the glucose treatment induced increase in 13C-DHA phosphatidylcholine and 13C-DHA lysophospholipids was curtailed, with further decline in 13C-DHA phosphatidylethanolamine plasmalogens. Conversely, with increasing birthweight centile glucose treatment induced increases in 13C-DHA triacylglycerols were exaggerated, while glucose treatment induced decreases in 13C-DHA phosphatidylethanolamine plasmalogens were diminished. Conclusions Maternal BMI and glycemia increased the production of different placental DHA lipids implying impact on different metabolic pathways. Glucose-induced elevation in placental DHA metabolism is moderated with higher maternal BMI. In turn, findings of associations between many DHA lipids with birthweight suggest that BMI and glycemia promote fetal growth partly through changes in placental DHA metabolism.

scholarly journals Host and Environmental Factors Affecting the Intestinal Microbiota in Chickens

2018 ◽  
Vol 9 ◽  
Author(s):  
Jannigje G. Kers ◽  
Francisca C. Velkers ◽  
Egil A. J. Fischer ◽  
Gerben D. A. Hermes ◽  
J. A. Stegeman ◽  
...  
Keyword(s):  
Environmental Factors ◽  
Intestinal Microbiota ◽  
Factors Affecting

The frequency of Enterobius vermicularis infection in children from Wielkopolska Voivodeship

2018 ◽  
Vol 54 (1) ◽  
pp. 5-9
Author(s):  
Marta Siekierska ◽  
Karolina Kot ◽  
Natalia Łanocha-Arendarczyk ◽  
Danuta Kosik-Bogacka
Keyword(s):  
Early Childhood ◽  
Preschool Children ◽  
Environmental Factors ◽  
Large Intestine ◽  
Young Age ◽  
Parasitic Diseases ◽  
Place Of Residence ◽  
Enterobius Vermicularis

<i>Enterobius vermicularis</i> is a cosmopolitan parasite of large intestine. <i>Enterobius vermicularis</i> infection is found mostly in closed human communities such as kindergartens, nurseries and orphanages. The aim of the study was to evaluate the frequency of <i>E. vermicularis</i> in preschool children from Wielkopolska Voivodeship. In addition, the aim was to determine the relationships between the gender of children, place of residence and the occurrence of enterobiasis and to define the most common symptoms of enterobiasis in infected children. There were 145 children (84 girls and 61 boys) aged 3-6 who attended kindergartens in Wielkopolskie voivodeship. Swabs from the anus area was used according to Graham’s method. The frequency of <i>E. vermicularis</i> infection in the studied children was 7.6%. There were no relationships between the gender of participants as well as the place of residence and the frequency of <i>E. vermicularis</i> infection. There was no relationship between the occurrence of symptoms of enterobiasis and <i>E. vermicularis</i> infection. The examination showed that the half of studied children infected with <i>E. vermicularis</i> had no symptoms of infection. Enterobiasis is the most common parasitosis in preschool and early childhood children. The prevalence of enterobiasis in humans is correlated with socio-environmental factors. On the basis of the presented study, it was found that in order to control the E. vermicularis infection, it would be necessary to regularly educate parents about the risks of parasitic diseases and to teach children the principles of hygiene from a young age.

Effects of Dietary Fiber and Protein Concentration on Growth, Feed Efficiency, Visceral Organ Weights and Large Intestine Microbial Populations of Swine

1989 ◽  
Vol 119 (6) ◽  
pp. 879-886 ◽  
Author(s):  
Friday O. I. Anugwa ◽  
Vincent H. Varel ◽  
James S. Dickson ◽  
Wilson G. Pond ◽  
Lennart P. Krook
Keyword(s):  
Dietary Fiber ◽  
Large Intestine ◽  
Feed Efficiency ◽  
Protein Concentration ◽  
Microbial Populations ◽  
Visceral Organ ◽  
Organ Weights

scholarly journals Microbiome and Metabolome Analyses Reveal Novel Interplay Between the Skin Microbiota and Plasma Metabolites in Psoriasis

2021 ◽  
Vol 12 ◽  
Author(s):  
Dongmei Chen ◽  
Jingquan He ◽  
Jinping Li ◽  
Qian Zou ◽  
Jiawei Si ◽  
...  
Keyword(s):  
Lipid Metabolism ◽  
Metabolic Pathways ◽  
Pathogenic Bacteria ◽  
Plasma Metabolites ◽  
Skin Microbiome ◽  
Inflammatory Skin Disease ◽  
Skin Microbiota ◽  
Plasma Metabolome ◽  
Pathological Mechanism ◽  
New Evidence

Psoriasis is a chronic inflammatory skin disease that affects millions of people worldwide. There is still no effective approach for the clinical treatment of psoriasis. This is largely due to the lack of understanding of the pathological mechanism. Here, we comprehensively characterized the skin microbiome and plasma metabolome alterations of psoriasis patients. We observed that some pathogenic bacteria, including Vibrio, were significantly increased in psoriasis patients. The metabolomics results showed alterations in some metabolic pathways, especially pathways for lipid metabolism. In addition, microbiome-specific metabolites, including bile acids and kynurenine, were significantly changed. Correlation analysis revealed the interplay between the skin microbiota and plasma metabolites, especially between Vibrio and several lipids. Our results provide new evidence for the interplay between the skin microbiome and plasma metabolites, which is dramatically disrupted in psoriasis patients. This study also revealed the mechanism underlying the pathogenesis of psoriasis.

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