scholarly journals Chlamydia trachomatis and Chlamydia pneumoniae Interaction with the Host: Latest Advances and Future Prospective

2019 ◽  
Vol 7 (5) ◽  
pp. 140 ◽  
Author(s):  
Marisa Di Pietro ◽  
Simone Filardo ◽  
Silvio Romano ◽  
Rosa Sessa
Keyword(s):  
Chlamydia Trachomatis ◽  
Sexually Transmitted Diseases ◽  
Host Defense ◽  
Chlamydia Pneumoniae ◽  
Inflammatory Diseases ◽  
Respiratory Pathogen ◽  
Current Evidence ◽  
Complex Interplay ◽  
Chronic Inflammatory Diseases ◽  
Sexually Transmitted

Research in Chlamydia trachomatis and Chlamydia pneumoniae has gained new traction due to recent advances in molecular biology, namely the widespread use of the metagenomic analysis and the development of a stable genomic transformation system, resulting in a better understanding of Chlamydia pathogenesis. C. trachomatis, the leading cause of bacterial sexually transmitted diseases, is responsible of cervicitis and urethritis, and C. pneumoniae, a widespread respiratory pathogen, has long been associated with several chronic inflammatory diseases with great impact on public health. The present review summarizes the current evidence regarding the complex interplay between C. trachomatis and host defense factors in the genital micro-environment as well as the key findings in chronic inflammatory diseases associated to C. pneumoniae.

scholarly journals The revealing of some of causative microorganisms for sexually-transmitted diseases in chronic salpingoophoritis, bacterial vaginosis and nonspecific bacterial vaginitis

2000 ◽  
Vol 49 (1) ◽  
pp. 19-22
Author(s):  
S. V. Ryshuk ◽  
D. F. Kostucheck ◽  
A. G. Boitsov
Keyword(s):  
Bacterial Vaginosis ◽  
Sexually Transmitted Diseases ◽  
Ureaplasma Urealyticum ◽  
Inflammatory Diseases ◽  
Mycoplasma Hominis ◽  
Vaginal Smears ◽  
Chronic Inflammatory Diseases ◽  
Sexually Transmitted ◽  
Pathologic Processes

The data on frequent combination of chronic inflammatory diseases of vagina and adnex can give the evidence for connection betzveen these pathologic processes. The frequency of Mycoplasma hominis findings in patients with bacterial vaginosis points to their possible ethioloic role in the pathology. At the same time, vaginal smears presenting Ureaplasma urealyticum in patients zvith bacterial vaginosis indicates their role in formation of pathology. One can suggest ethiologic mean of U.urealyticum in nonspecific bacterial vaginitis patients.

scholarly journals Prevalence of Sexually Transmitted Diseases and Transmission of HIV in Dhaka, Bangladesh

2009 ◽  
Vol 3 (1) ◽  
pp. 27-33
Author(s):  
Tahmina Shirin ◽  
Saidur Rahman ◽  
Fareha Jesmin Rabbi ◽  
Md Humayun Kabir ◽  
KZ Mamun
Keyword(s):  
Human Immunodeficiency Virus ◽  
Herpes Simplex ◽  
Chlamydia Trachomatis ◽  
Sexually Transmitted Diseases ◽  
Treponema Pallidum ◽  
Enzyme Linked Immunosorbent Assay ◽  
Sexually Transmitted ◽  
Immunodeficiency Virus ◽  
Simplex Virus

The prevalence of sexually transmitted diseases (STDs) among patients attending out patients department of Skin and Venereal diseases of Dhaka Medical College Hospital, Dhaka and Shahid Sohrawardy Hospital, Dhaka was studied. A total of 230 patients were enrolled in the study during the period of July, 2006 to May, 2007. Urethral and endocervical swabs were collected from the participants for detection of Neisseria gonorrheae (by culture), Chlamydia trachomatis (by immunochromatoghraphy) and blood samples for the detection of Treponema pallidum antibody (by rapid plasma regain and Treponema pallidum haemagglutination assay), Herpes simplex virus type 2 antibody (both IgM and IgG by enzyme linked immunosorbent assay) and Human Immunodeficiency virus antibody (by enzyme linked immunosorbent assay). Socio-demographic data and data regarding high-risk sexual behavior were also collected. Out of 230 participants, 199 (86.5%) were positive for STDs pathogens studied, among them, 98 (42.6%) were infected with single pathogen and 101 (43.9%) were suffering from multiple infections. The prevalences of N. gonorrheae, C. trachomatis, T. pallidum, and HSV type 2 were 90 (39.1%), 110 (47.8%), 28 (12.2%) and 88 (38.2%) respectively. However, none of them were positive for HIV infection. Use of condom was significantly associated with protection of the participants against STDs. Keywords: Sexually Transmitted Diseases, Neisseria gonorrhoeae, Chlamydia trachomatis, Treponema pallidum, Herpes simplex virus type-2, Human Immunodeficiency virus   doi: 10.3329/bjmm.v3i1.2968 Bangladesh J Med Microbiol 2009; 03 (01): 27-33

Infections/inflammation of the genital tract

2011 ◽  
pp. 1426-1428
Author(s):  
Franco Dondero ◽  
Francesco Lombardo
Keyword(s):  
Young Adults ◽  
Chlamydia Trachomatis ◽  
Sexually Transmitted Diseases ◽  
Sexual Behaviour ◽  
Genital Tract ◽  
Contraceptive Methods ◽  
Sexually Transmitted ◽  
Genital Apparatus ◽  
Urinary Infections

Sexually-transmitted diseases (STDs) are the primary cause of infections of the genital apparatus, and are an important cause of morbidity worldwide. These diseases diminished after the advent of antibiotics, but in the 1970s new sexual behaviour and use of non-protective contraceptive methods brought about a significant increase in genito-urinary infections, especially in young adults of fertile age. New diseases appeared alongside the classic infections syphilis, gonorrhoea, soft ulcers, venereal lymphogranuloma, and inguinal granuloma, and increased continuously in industrialised nations. Previously unknown pathogens such as Chlamydia trachomatis, genital Mycoplasma, and others came to the attention of andrologists, particularly because of often irreversible complications in the sexual and reproductive realm (1).

scholarly journals Chlamydia pneumoniae Resists Antibiotics in Lymphocytes

2003 ◽  
Vol 47 (6) ◽  
pp. 1972-1975 ◽  
Author(s):  
Hiroyuki Yamaguchi ◽  
Herman Friedman ◽  
Mayumi Yamamoto ◽  
Keigo Yasuda ◽  
Yoshimasa Yamamoto
Keyword(s):  
Epithelial Cells ◽  
Bacterial Growth ◽  
Chlamydia Pneumoniae ◽  
Inflammatory Diseases ◽  
Lymphoid Cells ◽  
Infection Model ◽  
Chronic Inflammatory Diseases

ABSTRACT Chlamydia pneumoniae infection of lymphocytes in blood has been well documented, and it is apparent that control of this pathogen in these cells may be critical in the development of chronic inflammatory diseases associated with infection by this bacterium. The activity of antibiotics against C. pneumoniae in lymphocytes was assessed in this study by utilizing an in vitro infection model with lymphoid cells. The results obtained indicated that although all of the antibiotics tested showed remarkable activity against bacterial growth in epithelial cells, C. pneumoniae in lymphocytes was less susceptible to antibiotics than was bacterial growth in epithelial cells, which are widely used for the evaluation of anti-C. pneumoniae antibiotics.

Pharmacophore based virtual screening for identification of marine bioactive compounds as inhibitors against macrophage infectivity potentiator (Mip) protein of Chlamydia trachomatis

RSC Advances ◽  
2016 ◽  
Vol 6 (23) ◽  
pp. 18946-18957 ◽  
Author(s):  
Vijayan Ramachandran ◽  
Elavarasi Padmanaban ◽  
Kalaiarasan Ponnusamy ◽  
Subbarao Naidu ◽  
Manoharan Natesan
Keyword(s):  
Chlamydia Trachomatis ◽  
Virtual Screening ◽  
Sexually Transmitted Diseases ◽  
Bioactive Compounds ◽  
Virulence Factor ◽  
Sexually Transmitted ◽  
Macrophage Infectivity Potentiator ◽  
Macrophage Infectivity

Macrophage infectivity potentiator (Mip) is the virulence factor fromChlamydia trachomatisthat is primarily responsible for causing sexually transmitted diseases (STDs) and blindness.

Concurrent gonococcal and chlamydial infections among men attending a sexually transmitted diseases clinic

2005 ◽  
Vol 16 (5) ◽  
pp. 357-361 ◽  
Author(s):  
A McMillan ◽  
K Manavi ◽  
H Young
Keyword(s):  
Retrospective Study ◽  
Chlamydia Trachomatis ◽  
Confidence Interval ◽  
Sexually Transmitted Diseases ◽  
Chlamydial Infection ◽  
Empirical Treatment ◽  
Heterosexual Men ◽  
Sexually Transmitted ◽  
High Prevalence ◽  
Sex With Men

The aim of this retrospective study was to determine the prevalence of Chlamydia trachomatis co-infection in men with gonorrhoea attending a sexually transmitted diseases clinic in Edinburgh, Scotland. During the study period, there were 660 cases of culture-proven gonorrhoea. Chlamydial DNA was detected in the urethra in 79 (31%; 95% confidence interval [CI], 25–37%) heterosexual men who have sex with women (MSW); the median age was significantly lower than those with gonorrhoea alone (24.0 versus 30.0; P < 0.0005). The prevalence of urethral chlamydial infection among MSW was significantly higher than among men who have sex with men (MSM) (32 [12%; 95% CI, 8–16%] of 268 MSM) (χ2 = 27.21; P < 0.001). Sixteen (24%; 95% CI, 14–34%) of 68 MSM with rectal gonorrhoea had concurrent rectal chlamydial infection. The high prevalence of concurrent gonorrhoea and chlamydiae therefore warrants empirical treatment and/or testing for chlamydia in all men with urethral gonorrhoea.

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