scholarly journals Editorial for the Special Issue on Micro/Nanofluidic Devices for Single Cell Analysis, Volume II

Micromachines ◽  
2021 ◽  
Vol 12 (8) ◽  
pp. 875
Author(s):  
Tuhin Subhra Santra ◽  
Fan-Gang Tseng
Keyword(s):  
Drug Discovery ◽  
Single Cell ◽  
Single Cell Analysis ◽  
Compositional Heterogeneity ◽  
Cell Analysis ◽  
Special Issue ◽  
Drug Discovery And Development ◽  
Nanofluidic Devices

The functional, genetic, or compositional heterogeneity of healthy and diseased tissues promotes significant challenges to drug discovery and development [...]

scholarly journals Single-cell analysis tools for drug discovery and development

2015 ◽  
Vol 15 (3) ◽  
pp. 204-216 ◽  
Author(s):  
James R. Heath ◽  
Antoni Ribas ◽  
Paul S. Mischel
Keyword(s):  
Drug Discovery ◽  
Single Cell ◽  
Single Cell Analysis ◽  
Cell Analysis ◽  
Drug Discovery And Development ◽  
Analysis Tools

scholarly journals Micro/Nanofluidic Devices for Single Cell Analysis

Micromachines ◽  
2014 ◽  
Vol 5 (2) ◽  
pp. 154-157 ◽  
Author(s):  
Tuhin Santra ◽  
Fan Tseng
Keyword(s):  
Single Cell ◽  
Single Cell Analysis ◽  
Cell Analysis ◽  
Nanofluidic Devices

scholarly journals Advanced Top-Down Fabrication for a Fused Silica Nanofluidic Device

Micromachines ◽  
2020 ◽  
Vol 11 (11) ◽  
pp. 995
Author(s):  
Kyojiro Morikawa ◽  
Yutaka Kazoe ◽  
Yuto Takagi ◽  
Yoshiyuki Tsuyama ◽  
Yuriy Pihosh ◽  
...  
Keyword(s):  
Single Cell ◽  
Single Cell Analysis ◽  
Fused Silica ◽  
Cell Analysis ◽  
Top Down ◽  
Silica Substrate ◽  
Single Substrate ◽  
Nanofluidic Devices ◽  
Nanofluidic Device ◽  
Significant Attention

Nanofluidics have recently attracted significant attention with regard to the development of new functionalities and applications, and producing new functional devices utilizing nanofluidics will require the fabrication of nanochannels. Fused silica nanofluidic devices fabricated by top-down methods are a promising approach to realizing this goal. Our group previously demonstrated the analysis of a living single cell using such a device, incorporating nanochannels having different sizes (102–103 nm) and with branched and confluent structures and surface patterning. However, fabrication of geometrically-controlled nanochannels on the 101 nm size scale by top-down methods on a fused silica substrate, and the fabrication of micro-nano interfaces on a single substrate, remain challenging. In the present study, the smallest-ever square nanochannels (with a size of 50 nm) were fabricated on fused silica substrates by optimizing the electron beam exposure time, and the absence of channel breaks was confirmed by streaming current measurements. In addition, micro-nano interfaces between 103 nm nanochannels and 101 μm microchannels were fabricated on a single substrate by controlling the hydrophobicity of the nanochannel surfaces. A micro-nano interface for a single cell analysis device, in which a nanochannel was connected to a 101 μm single cell chamber, was also fabricated. These new fabrication procedures are expected to advance the basic technologies employed in the field of nanofluidics.

scholarly journals New frontiers in single-cell analysis

2008 ◽  
Vol 5 (suppl_2) ◽  
Author(s):  
Richard H Templer ◽  
Oscar Ces
Keyword(s):  
Single Cell ◽  
Single Cell Analysis ◽  
Driving Forces ◽  
Population Based ◽  
Cellular Heterogeneity ◽  
Cell Analysis ◽  
Special Issue ◽  
Technological Advances ◽  
Rare Cells ◽  
Averaging Techniques

For this special issue of J. R. Soc. Interface we present an overview of the driving forces behind technological advances in the field of single-cell analysis. These range from increasing our understanding of cellular heterogeneity through to the study of rare cells, areas of research that cannot be tackled effectively using current high-throughput population-based averaging techniques.

Author response for "Immunocyte single cell analysis of vaccine‐induced narcolepsy"

2020 ◽  
Author(s):  
Alexander Lind ◽  
Falastin Salami ◽  
Anne‐Marie Landtblom ◽  
Lars Palm ◽  
Åke Lernmark ◽  
...  
Keyword(s):  
Single Cell ◽  
Single Cell Analysis ◽  
Author Response ◽  
Cell Analysis
Sign in / Sign up

Export Citation Format

Share Document