scholarly journals Wearable Sensors and Systems for Wound Healing-Related pH and Temperature Detection

Micromachines ◽  
2021 ◽  
Vol 12 (4) ◽  
pp. 430
Author(s):  
Ning Tang ◽  
Youbin Zheng ◽  
Xue Jiang ◽  
Cheng Zhou ◽  
Han Jin ◽  
...  
Keyword(s):  
Wound Healing ◽  
Wearable Sensors ◽  
Wound Dressings ◽  
Wound Management ◽  
Large Area ◽  
3 Dimensional ◽  
Temperature Detection ◽  
Reliable Monitoring ◽  
Identification Threshold

Wound healing is a complex tissue regeneration process involving many changes in multiple physiological parameters. The pH and temperature of a wound site have long been recognized as important biomarkers for assessing wound healing status. For effective wound management, wound dressings integrated with wearable sensors and systems used for continuous monitoring of pH and temperature have received much attention in recent years. Herein, recent advances in the development of wearable pH and temperature sensors and systems based on different sensing mechanisms for wound status monitoring and treatment are comprehensively summarized. Challenges in the areas of sensing performance, infection identification threshold, large-area 3-dimensional detection, and long-term reliable monitoring in current wearable sensors/systems and emerging solutions are emphasized, providing critical insights into the development of wearable sensors and systems for wound healing monitoring and management.

EP.TU.854Happy Patients and Updated Open Wound Management Protocols

2021 ◽  
Vol 108 (Supplement_7) ◽  
Author(s):  
Harish Peri ◽  
Rafique Umer Harvitkar
Keyword(s):  
Chronic Wound ◽  
Clinical Audit ◽  
Wound Dressings ◽  
Wound Management ◽  
Open Wound ◽  
Current Management ◽  
Pdsa Cycle ◽  
Management Protocol ◽  
Open Injuries

Abstract Introduction Open injuries have a potential for serious bacterial wound infections and may lead to long term disabilities, chronic wound or bone infection, and even death. This QI study was undertaken to ring in changes to the current management protocol and align them as per WHO guidelines. Method Implementing changes through a Plan-Do-Study-Act (PDSA) cycle post an initial clinical audit among 38 patients of the organization. Re-audits were done to measure the outcome against the standard and establish a new protocol. Results Initial audit showed only a dismal 37% (n = 14) of patients being managed as per WHO protocol. Patient satisfaction percentage (as measured by a questionnaire) was also low with only 54% of patients satisfied with the treatment. Significant variations were noted post implementation of changes after the first PDSA cycle where >90% (n = 35) of patients reported that they noticed better wound healing, transition to optimal performance and were satisfied with treatment outcomes. Conclusions Timely wound dressings, appropriate antibiotic prophylaxis and increased patient’s awareness on wound hygiene through means of regular educational sessions and updated management protocols have led to healthier patients, lesser long term disabilities and happy patients.

The significance of collagen dressings in wound management: a review

2018 ◽  
Vol 27 (10) ◽  
pp. 692-702 ◽  
Author(s):  
Frank Pallaske ◽  
Anett Pallaske ◽  
Kurt Herklotz ◽  
Joachim Boese-Landgraf
Keyword(s):  
Wound Healing ◽  
Health Professionals ◽  
Clinical Studies ◽  
Critical Appraisal ◽  
Wound Dressings ◽  
Wound Management ◽  
Complex Field ◽  
The Right ◽  
New Applications

Clinical experience and research has improved our understanding of wound healing which, in turn, has enabled health professionals to aid wound healing and manufacturers to develop modern wound dressings. The significant role of collagen in wound healing has led to the development of numerous products on the basis of this biological material. The main focus of this review is to provide a critical appraisal of publications about collagen and acellular collagen dressings with a fleece-like or spongy structure. It is intended for clinicians and researchers, and aims to keep them up-to-date in the complex field of interactive, collagen-based wound dressings, including their manufacture, combination possibilities, mechanisms of action, performance in the promotion of wound healing and indications. Despite the small number of clinical studies, the importance of acellular collagen dressings with a fleece- or sponge-like structure is likely to increase in the future. As there is no ideal wound dressing, the knowledge attained is meant to support health professionals in selecting the right product, and pave the way for new applications and clinical studies.

Wearable Biosensors for Monitoring Wound Healing

2008 ◽  
Vol 57 ◽  
pp. 80-87 ◽  
Author(s):  
Stéphanie Pasche ◽  
Silvia Angeloni ◽  
Réal Ischer ◽  
Martha Liley ◽  
Jean Luprano ◽  
...  
Keyword(s):  
Wound Healing ◽  
Detection System ◽  
Wearable Sensors ◽  
Healing Process ◽  
Optical Signal ◽  
Wound Dressings ◽  
Wound Healing Process ◽  
Reactive Protein ◽  
Novel Technology ◽  
Inflammatory Proteins

Continuous health monitoring often requires hospitalization, which can become an expensive and inconvenient choice for the patient. In this perspective, wearable sensors that allow in situ biosensing constitute a very promising technology. This work aims to develop immunosensors for continuous monitoring of the wound healing process, based on pH changes, as well as on the concentrations of inflammatory proteins such as the C-reactive protein (CRP). Sensing principles include the use of responsive hydrogels that swell in response to changes in the surroundings, and the use of functional surfaces that specifically recognize the target protein. The detection principle is based on an optical signal, using the evanescent field of light propagating along a waveguide, probing refractive index changes. An optical sensing system that can be integrated in a wound dressing patch has been designed, including a white light source (LED), and a spectrometer for detection. The sensor was successfully tested in the laboratory with biological samples (blood serum), demonstrating reversible pH measurements between pH 6-8, and detection of changes in the concentration of CRP between 1 and 100 μg/ml. The sensor will later be integrated into wound dressings or bandages, forming a sensing patch that is connected via optical fibres and electrical wires to the detection system and power supply. This novel technology will be particularly valuable in applications such as the supervision of skin grafts and ulcer treatments.

scholarly journals Study of hydrocellular functional material as microbicidal wound dressing for diabetic wound healing

2021 ◽  
Vol 19 ◽  
pp. 228080002110549
Author(s):  
Michael Rodrigues ◽  
Thilagavati Govindharajan
Keyword(s):  
Wound Healing ◽  
Wound Dressing ◽  
Wound Care ◽  
Cost Effective ◽  
Wound Dressings ◽  
Wound Management ◽  
Histopathological Analysis ◽  
Diabetic Wound ◽  
Functional Material ◽  
Diabetic Wound Healing

A hydrocellular functional material as a wound dressing is developed and it is found to be superior in its efficacy as compared to some of the comparator controls in diabetic wound healing studies. A study on wound contraction and Histopathological analysis is done in rats. The efficacy of the dressing is comparable to the established wound dressings like Carboxymethyl cellulose alginate dressings and autolytic enzyme based hydrogel. It is found to be superior to Polyhexamethylene biguanide dressing used as reference controls in this study. The reason for good wound healing performance of the dressing can be attributed to a combined property of effective exudates management and broad spectrum antimicrobial effect. The concept of functional hydro cellular material has shown good results due to the excellent balance of exudates pickup and drying it out. This ensures moist wound healing conditions on the wound. Because of its porous nature it allows good air flow and gaseous exchange in the structure. The cationic sites created on the surface of the dressing ensure a good antimicrobial action on the exudates in the dressing. It reduces the infection load on the wound. The nonleaching property of the dressing also helps in preventing the generation of more resistant and mutant strains of the microbes. The developed dressing can be used as a relatively durable long lasting dressing for wound management in diabetic wounds. The need of repetitive wound dressing changes can be brought down with this concept of dressing. It is not only cost effective in terms of its material cost but also is a cost effective solution when entire wound management cost is considered. Such novel wound dressing material can change the quality of life of diabetic wound patients especially in developing world, where access to functional advanced wound care dressings is limited.

scholarly journals Collagen-Based Nanofibers for Skin Regeneration and Wound Dressing Applications

Polymers ◽  
2021 ◽  
Vol 13 (24) ◽  
pp. 4368
Author(s):  
Zintle Mbese ◽  
Sibusiso Alven ◽  
Blessing Atim Aderibigbe
Keyword(s):  
Wound Healing ◽  
Wound Dressing ◽  
Cellular Proliferation ◽  
Healing Process ◽  
Skin Regeneration ◽  
Wound Dressings ◽  
Wound Management ◽  
Major Constituent ◽  
Wound Healing Process ◽  
Frequent Change

Skin regeneration after an injury is very vital, but this process can be impeded by several factors. Regenerative medicine is a developing biomedical field with the potential to decrease the need for an organ transplant. Wound management is challenging, particularly for chronic injuries, despite the availability of various types of wound dressing scaffolds in the market. Some of the wound dressings that are in clinical practice have various drawbacks such as poor antibacterial and antioxidant efficacy, poor mechanical properties, inability to absorb excess wound exudates, require frequent change of dressing and fails to offer a suitable moist environment to accelerate the wound healing process. Collagen is a biopolymer and a major constituent of the extracellular matrix (ECM), making it an interesting polymer for the development of wound dressings. Collagen-based nanofibers have demonstrated interesting properties that are advantageous both in the arena of skin regeneration and wound dressings, such as low antigenicity, good biocompatibility, hemostatic properties, capability to promote cellular proliferation and adhesion, and non-toxicity. Hence, this review will discuss the outcomes of collagen-based nanofibers reported from the series of preclinical trials of skin regeneration and wound healing.

scholarly journals Original hardware-software method for treatment of infected superficial wounds in a liquid environment

2019 ◽  
Vol 8 (4) ◽  
Author(s):  
Aleksandr A. Basov ◽  
Vadim V. Malyshko ◽  
Anna A. Elkina ◽  
Arkadiy V. Moiseev ◽  
Stepan S. Dzhimak
Keyword(s):  
Wound Healing ◽  
Wound Repair ◽  
Wound Dressings ◽  
Wound Management ◽  
Software System ◽  
The Novel ◽  
Wound Irrigation ◽  
Liquid Environment ◽  
Novel Device ◽  
Study Results

Aim ― development of a hardware-software system allowing to treat infected superficial wounds in a liquid environment, designed to provide continuous flow of various irrigation solutions (depending on the wound healing stage) under airtight and water-resistant film tightly fixed over the wound. Methods ― in this experiment wound irrigation with antiseptic, oxidizing antiseptic and osmotically active agents with subsequent exposure and drainage was performed using the novel device. Efficacy of the proposed hardware-software system was evaluated by comparing it with standard wound dressings by planimetry and wound biopsy results. Results ― according to study results the novel device reduces the time of wound healing by 26.1%, while the time to wound proliferation is 1.7 times shorter when compared with standard wound dressings. Conclusion ― the proposed method stimulates wound repair and limits purulent inflammation in infected wounds. Using the novel method of superficial wound management helps to prevent the development of re-infection and suppuration.

scholarly journals Collagen Based Sponges for Wound Healing

2019 ◽  
Vol 9 (2S2) ◽  
pp. 916-920
Keyword(s):  
Wound Healing ◽  
Wound Dressing ◽  
Wound Repair ◽  
Wound Dressings ◽  
Wound Management ◽  
Repair System ◽  
Tissue Formation ◽  
Fish Scales ◽  
Healing Efficiency ◽  
The Common

Nowadays, wound healing is the common and simple problems occur in our society. Wound healing is the multi factorial process which includes inflammation, reepithelialisation, collagen deposition, and angiogenesis. Wound repair system is indispensable to enhance the proper functioning of skin. Normally, wound dressing is either momentary or lasting, wound dressings has been intended to improve the wound repair. Those wound dressing are required to wrap the large surfaced open wounds such as widespread burns, pressure ulcers, foot sores etc., wound healing substance should have some important features such as, high healing efficiency, anti-scar formation, providing favourable atmosphere for wound management. The collagen plays an important role in tissue formation and has more effect on wound healing. In this work collagen sponge is prepared from fish scales and to increase the antibacterial efficacy need extract has been added.

Long-term monitoring of acute wound healing from beneath the primary wound dressings

2018 ◽  
Author(s):  
Atte Kekonen ◽  
Mikael Bergelin ◽  
Jan-Erik Eriksson ◽  
Mikko Vesa ◽  
Max Johansson ◽  
...  
Keyword(s):  
Wound Healing ◽  
Wound Dressings ◽  
Acute Wound ◽  
Long Term Monitoring ◽  
Term Monitoring

Wound dressings. A comparison of classes and their principles of use

1994 ◽  
Vol 84 (9) ◽  
pp. 463-469 ◽  
Author(s):  
CS Choate
Keyword(s):  
Health Care Providers ◽  
Wound Dressing ◽  
Wound Dressings ◽  
Wound Management ◽  
Care Providers ◽  
Management Guidelines ◽  
Sodium Calcium ◽  
Individual Product ◽  
Selection Of

Selection of an appropriate wound dressing, to potentiate healing, demands knowledge about varying classes of dressings. With the growing number of wound dressings available, health care providers must understand both the principles of dressing development as well as the qualities of each individual product. The author compares five classes of wound dressings: hydrocolloids, hydrogels, films, foams, and sodium/calcium alginates. Also, principles of dressing selection and long-term wound management guidelines are presented.

scholarly journals Wearable Sensors for the Detection of Biomarkers for Wound Infection

Biosensors ◽  
2021 ◽  
Vol 12 (1) ◽  
pp. 1
Author(s):  
Alexandra Pusta ◽  
Mihaela Tertiș ◽  
Cecilia Cristea ◽  
Simona Mirel
Keyword(s):  
Wound Healing ◽  
Uric Acid ◽  
Lactic Acid ◽  
Wound Infection ◽  
Inflammatory Mediators ◽  
Wearable Sensors ◽  
Major Complication ◽  
Wound Dressings ◽  
Infection Diagnosis ◽  
Detection Of Biomarkers

Infection represents a major complication that can affect wound healing in any type of wound, especially in chronic ones. There are currently certain limitations to the methods that are used for establishing a clinical diagnosis of wound infection. Thus, new, rapid and easy-to-use strategies for wound infection diagnosis need to be developed. To this aim, wearable sensors for infection diagnosis have been recently developed. These sensors are incorporated into the wound dressings that are used to treat and protect the wound, and are able to detect certain biomarkers that can be correlated with the presence of wound infection. Among these biomarkers, the most commonly used ones are pH and uric acid, but a plethora of others (lactic acid, oxygenation, inflammatory mediators, bacteria metabolites or bacteria) have also been detected using wearable sensors. In this work, an overview of the main types of wearable sensors for wound infection detection will be provided. These sensors will be divided into electrochemical, colorimetric and fluorimetric sensors and the examples will be presented and discussed comparatively.

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